Breast-feeding<\/em><\/p>\n\n\n\nTell your doctor if you are breastfeeding or planning to start breastfeeding.\u00a0Losartan\u00a0Actavis is not recommended for breastfeeding and your doctor may choose another treatment for you if you want to breastfeed your baby, especially if your baby is newborn or born prematurely.<\/p>\n\n\n\n
Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
No studies on the ability to drive and use machines have been performed.<\/p>\n\n\n\n
Losartan\u00a0Actavis is\u00a0unlikely to\u00a0directly affect your ability to drive or use machines, but like many other\u00a0antihypertensive\u00a0drugs,\u00a0Losartan\u00a0Actavis may cause dizziness or drowsiness in some people.\u00a0If you experience dizziness or drowsiness, consult your doctor before performing any such activity.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Losartan Actavis contains sodium<\/h2>\n\n\n\n
This medicine contains less than 1 mmol (23 mg) sodium per tablet, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
3. How to use Losartan Actavis<\/h2>\n\n\n\n
Always use this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure. Your doctor will decide on the appropriate dose of Losartan Actavis, depending on your condition and whether you are taking other medicines.<\/p>\n\n\n\n
Adult patients with high blood pressure<\/strong><\/p>\n\n\n\nTreatment is usually started with 50 mg\u00a0losartan\u00a0(a\u00a050 mg\u00a0tablet\u00a0Losartan\u00a0Actavis) once daily.\u00a0Maximum blood pressure-lowering effect is obtained after 3-6 weeks after starting treatment.\u00a0In some patients, the\u00a0dose\u00a0may\u00a0need to be increased to 100 mg\u00a0losartan\u00a0(two\u00a0Losartan\u00a0Actavis 50 mg\u00a0tablets\u00a0or one\u00a0Losartan\u00a0Actavis 100 mg\u00a0tablet\u00a0) once daily.<\/p>\n\n\n\n
Use for children and adolescents<\/strong><\/p>\n\n\n\nChildren under 6 years of age<\/em><\/p>\n\n\n\nLosartan Actavis is not recommended for use in children below 6 years of age, as it has not been shown to work in this age group.<\/p>\n\n\n\n
Children aged 6 to 18 years<\/em><\/p>\n\n\n\nThe recommended starting dose for patients weighing between 20 and 50 kg is 0.7 mg losartan per kg body weight once daily (up to 25 mg Losartan Actavis). Your doctor may need to increase the dose in case of insufficient blood pressure control.<\/p>\n\n\n\n
Other dosage forms of this medicine may be more suitable for children, consult a doctor or pharmacist.<\/p>\n\n\n\n
Adult patients with high blood pressure and type 2 diabetes<\/strong><\/p>\n\n\n\nTreatment is usually started with 50 mg losartan (one Losartan Actavis 50 mg tablet ) once daily. Dose one can then be increased to 100 mg losartan (two tablets Losartan Actavis 50 mg or one tablet Losartan Actavis 100 mg) once daily depending on your blood pressure response.<\/p>\n\n\n\n
Losartan tablets can be given with other antihypertensive drugs<\/p>\n\n\n\n
(eg diuretic calcium channel blockers, alpha- or beta-blockers and centrally acting drugs) as well as insulin and other commonly used drugs that lower blood glucose levels (eg sulphonylureas, glitazones and glucosidase inhibitors).<\/p>\n\n\n\n
Adult patients with heart failure<\/strong><\/p>\n\n\n\nTreatment is usually started with 12.5 mg losartan (one Losartan Actavis 12.5 mg tablet ) once daily. Depending on your condition, the dose should be increased step by step, weekly (ie 12.5 mg daily during the first week, 25 mg daily during the second week, 50 mg daily during the third week, 100 mg daily during the fourth week, 150 mg daily for the fifth week), up to a maintenance dose determined by your doctor. A maximum dose of 150 mg losartan (eg three tablets Losartan Actavis 50 mg or one tablet of both Losartan Actavis 100 mg and Losartan Actavis 50 mg) once daily can be used.<\/p>\n\n\n\n
In the treatment of\u00a0heart failure,\u00a0losartan is\u00a0often combined\u00a0with a diuretic (a medicine that increases the excretion of urine from your kidneys) and\/or\u00a0digitalis\u00a0(a medicine that helps the heart to function better and more efficiently) and\/or a \u03b2-blocker.<\/p>\n\n\n\n
Dosage for special patient groups<\/strong><\/p>\n\n\n\nDoctors may\u00a0prescribe\u00a0lower\u00a0doses, especially at the start of treatment for patients treated with\u00a0high-dose\u00a0diuretics, patients with hepatic impairment, and patients over 75 years of age.\u00a0Losartan\u00a0Actavis is not recommended for patients with severe hepatic impairment (see section \u201cDo not use\u00a0Losartan\u00a0Actavis\u201d).<\/p>\n\n\n\n
Administration<\/strong><\/p>\n\n\n\nThe tablets should be swallowed with a glass of water.\u00a0Try to take your daily\u00a0dose\u00a0at about the same time each day.\u00a0You must continue to take\u00a0Losartan\u00a0Actavis until your doctor tells you otherwise<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
If you experience any of the following, stop taking Losartan Actavis and talk to your doctor immediately or seek medical attention:<\/p>\n\n\n\n
A severe\u00a0allergic reaction\u00a0(rash,\u00a0itching, swelling of the face, lips, mouth, or throat, which can cause difficulty swallowing and breathing) (\u00a0angioedema\u00a0).<\/p>\n\n\n\n
This is a serious but rare\u00a0side effect, which may affect up to 1 in 1,000 patients.\u00a0You may need\u00a0emergency\u00a0medical care or hospitalization<\/p>\n\n\n\n
The following side effects have been reported with losartan:<\/p>\n\n\n\n
Common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n- dizziness<\/li>
- a feeling of spinning ( vertigo )<\/li>
- low blood pressure (especially after heavy fluid loss from the body eg in patients with severe heart failure or during treatment with high-dose diuretics)<\/li>
- dose-related orthostatic effects such as a drop in blood pressure when getting up quickly from a lying or sitting position<\/li>
- impotence<\/li>
- fatigue<\/li>
- low blood sugar ( hypoglycaemia )<\/li>
- excess potassium in the blood ( hyperkalaemia )<\/li>
- change in renal function including renal failure<\/li>
- decreased number of red blood cells ( anemia )<\/li>
- increase in urea in the blood and increase in serum creatinine and serum potassium in patients with heart failure .<\/li><\/ul>\n\n\n\n
Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n- somnolence<\/li>
- headache<\/li>
- sleep disorders<\/li>
- feeling of heart beating (palpitations)<\/li>
- severe chest pain ( angina pectoris )<\/li>
- shortness of breath ( dyspnoea )<\/li>
- abdominal pain<\/li>
- constipation<\/li>
- diarrhea<\/li>
- nausea<\/li>
- vomiting<\/li>
- hives ( urticaria )<\/li>
- itching ( pruritus )<\/li>
- rash<\/li>
- local swelling ( edema )<\/li>
- cough.<\/li><\/ul>\n\n\n\n
Rare (may <\/em>affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n- hypersensitivity<\/li>
- inflammation of the blood vessels ( vasculitis including Henoch-Sch\u00f6nlein purpura)<\/li>
- numbness or tingling ( paresthesias )<\/li>
- fainting ( syncope )<\/li>
- fast and irregular heartbeat ( atrial fibrillation )<\/li>
- stroke<\/li>
- inflammation of the liver ( hepatitis )<\/li>
- elevated liver enzyme levels ( alanine aminotransferase (S- ALAT )), usually reversible after discontinuation of treatment.<\/li><\/ul>\n\n\n\n
Has been reported (occurs in an unknown number of users <\/em>)<\/em> <\/p>\n\n\n\n- decreased platelet count<\/li>
- migraine<\/li>
- abnormal liver function<\/li>
- muscle and joint pain<\/li>
- flu-like symptoms<\/li>
- back pain and urinary tract infection<\/li>
- increased sensitivity to sunlight ( photosensitivity )<\/li>
- unexplained muscle pain with dark (tea colored) urine ( rhabdomyolysis )<\/li>
- impotence<\/li>
- inflammation of the pancreas ( pancreatitis )<\/li>
- low levels of sodium in the blood ( hyponatremia )<\/li>
- Depression<\/li>
- general malaise<\/li>
- ringing, buzzing, throbbing or clicking in the ears ( tinnitus )<\/li>
- taste changes ( dysgeusia ).<\/li><\/ul>\n\n\n\n
Side effects in children are similar to those reported in adults.<\/p>\n\n\n\n
How to store Losartan Actavis<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton and label after EXP, or blisters after EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n
12.5 mg, 25 mg in blisters:<\/em><\/p>\n\n\n\nStore in the original package. Sensitive to light.<\/p>\n\n\n\n
50 mg, 100 mg in blisters:<\/em><\/p>\n\n\n\nDo not store above 25 \u00b0 C. Store in the original package. Sensitive to light.<\/p>\n\n\n\n
Can:<\/em><\/p>\n\n\n\nNo special storage instructions.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is losartan potassium.Losartan Actavis 12.5 mg film-coated tablets: Each Losartan Actavis 12.5 mg film-coated tablet contains 12.5 mg of losartan potassium.Losartan Actavis 25 mg film-coated tablets: Each Losartan Actavis 25 mg film-coated tablet contains 25 mg of losartan potassium.Losartan Actavis 50 mg film-coated tablets: Each Losartan Actavis 50 mg film-coated tablet contains 50 mg of losartan potassium.Losartan Actavis 100 mg film-coated tablets: Each Losartan Actavis 100 mg film-coated tablet contains 100 mg of losartan potassium.<\/li>
- Other ingredients are:Tablet core<\/em> : mannitol, microcrystalline cellulose, croscarmellose sodium, povidone K29 \/ 32, magnesium stearate.Film coating<\/em> : Hypromellose 6, titanium dioxide (E171), talc, propylene glycol<\/li><\/ul>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Losartan\u00a0Actavis 12.5 mg film-coated tablets: white, round biconvex film-coated tablets, without the notch, labeled 1L, size: 6 mm<\/p>\n\n\n\n
Losartan\u00a0Actavis 25 mg film-coated tablets: white, round biconvex, film-coated tablets, without the notch, labeled 2L, size: 8 mm<\/p>\n\n\n\n
Losartan Actavis 50 mg film-coated tablets: white, round biconvex, film-coated tablets, scored, marked 3L, size: 10 mm<\/p>\n\n\n\n
Losartan Actavis 100 mg film-coated tablets: white, oval biconvex, film-coated tablets, scored, 4L, size: 18.3×9.2 mm<\/p>\n\n\n\n
The 50 mg and 100 mg tablets can be divided into two equal\u00a0doses.<\/p>\n\n\n\n
Pack sizes:<\/p>\n\n\n\n
Blister:<\/p>\n\n\n\n
7, 10, 14, 15, 20, 21, 28, 30, 50, 56, 90, 98, 100, 210 tablets<\/p>\n\n\n\n
Hospital packaging: 280 tablets<\/p>\n\n\n\n
Can:<\/p>\n\n\n\n
100, 250 film-coated tablets.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/em><\/p>\n\n\n\nActavis Group PTC EHF<\/p>\n\n\n\n
Reykjavikurvegur 76-78<\/p>\n\n\n\n
220 Hafnarfj\u00f6r\u00f0ur<\/p>\n\n\n\n
Iceland<\/p>\n\n\n\n
Manufacturer<\/em><\/p>\n\n\n\nBalkanpharma Dupnitsa AD<\/p>\n\n\n\n
3 Samokovsko Schosse Str.<\/p>\n\n\n\n
Dupnitsa 2600<\/p>\n\n\n\n
Bulgaria<\/p>\n\n\n\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Losartan Actavis belongs to a group of medicines called angiotensin II receptor antagonists. Angiotensin II is a body-specific substance that binds to receptors in blood vessels and causes them to constrict. This causes blood pressure to rise. Losartan Actavis prevents the binding of angiotensin II to these receptors , which causes the blood vessels to dilate and the blood pressure to drop. Losartan prevents further renal impairment in patients with high blood pressure and type 2 diabetes .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15579],"tags":[16457,16451,16452,16455,16456,6501,6503,6504,16453,6502,16454,16450],"class_list":["post-17098","post","type-post","status-publish","format-standard","hentry","category-medicines","category-l","tag-benefits-of-losartan-actavis","tag-benefits-of-losartan-potassium","tag-losartan-actavis","tag-losartan-actavis-side-effects","tag-losartan-actavis-tablet","tag-losartan-potassium","tag-losartan-potassium-side-effects","tag-losartan-potassium-tablet","tag-what-is-losartan-actavis","tag-what-is-losartan-potassium","tag-what-losartan-actavis-is-used-for","tag-what-losartan-potassium-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17098","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17098"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17098\/revisions"}],"predecessor-version":[{"id":17141,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17098\/revisions\/17141"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17098"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17098"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}