{"id":16838,"date":"2021-12-22T07:41:14","date_gmt":"2021-12-22T07:41:14","guid":{"rendered":"https:\/\/zeepedia.com\/?p=16838"},"modified":"2022-12-03T17:59:27","modified_gmt":"2022-12-03T17:59:27","slug":"lithionite","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/lithionite\/","title":{"rendered":"Lithionite &#8211; Lithium Sulfate Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Lithionit 42 mg (6 mmol)&nbsp;Prolonged Release Lithium Sulfate Tablet<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Lithionite Is And What It Is Used For<\/h2>\n\n\n\n<p>Lithionite contains the active substance lithium and has a preventive effect against both manic (abnormal agitation) and depressive (pronounced <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">depression<\/a>) phases in patients with&nbsp;bipolar disorder.&nbsp;In hospitals, Lithionite can also be given in acute manic conditions.&nbsp;The full effect is then reached within about 1 week.&nbsp;The mechanism of action of lithium is not fully understood.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before Taking Lithionite<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Lithionite<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have severe kidney problems.<\/li><li>If you have cardiovascular disease.<\/li><li>If you have severely disturbed the salt and fluid balance.<\/li><li>If you are allergic to lithium sulfate or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Lithionite:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have heart problems (&nbsp;ECG&nbsp;changes).<\/li><li>If you have high&nbsp;blood pressure.<\/li><li>If you have&nbsp;myasthenia gravis&nbsp;(severe muscle weakness).<\/li><li>If you have&nbsp;epilepsy&nbsp;or other seizures.<\/li><li>If you have mild to moderate kidney problems.<\/li><li>If you have any kind of brain damage.<\/li><li>If you are on a low-salt diet or dieting diet.<\/li><li>If you drink large amounts of coffee or tea.<\/li><li>If you are elderly, especially if you are being treated with diuretics,&nbsp;ACE inhibitors,&nbsp;or anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;).<\/li><\/ul>\n\n\n\n<p><em>Always consult a doctor or clinic for extra check-ups at the following times:<\/em><\/p>\n\n\n\n<p>in diseases with <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">fever<\/a> and sweating (for example&nbsp;influenza&nbsp;), in long-term diarrhea or vomiting, and in connection with dieting or if troublesome&nbsp;side effects&nbsp;occur.<\/p>\n\n\n\n<p>Dietary habits, especially the salt in the food, must not be significantly changed after your <strong>Lithionit dosering<\/strong> has been adjusted using blood tests.&nbsp;The lithium content in the blood changes when you change the salt intake.&nbsp;Large amounts of coffee or tea can also affect the effect.&nbsp;Therefore, consult a physician in case of high consumption of coffee or tea.<\/p>\n\n\n\n<p>Treatment with lithium can lead to&nbsp;hypothyroidism&nbsp;(lack of thyroid hormone).&nbsp;Your doctor may therefore want to check the function of your&nbsp;thyroid gland&nbsp;regularly.<\/p>\n\n\n\n<p>Treatment with lithium can lead to hyperparathyroidism (overactive parathyroid glands).&nbsp;Your doctor may therefore want to check the calcium level in your blood regularly.<\/p>\n\n\n\n<p>Patients with kidney problems: The doctor should monitor the level of lithium in the blood and adjust the&nbsp;dose&nbsp;accordingly.&nbsp;You should not take Lithionite if you have severe&nbsp;kidney failure&nbsp;(see section 2 \u201cDo not take Lithionite\u201d).<\/p>\n\n\n\n<p>Kidney tumors: Patients with severe renal impairment who have received lithium for more than 10 years may be at risk of developing a benign or malignant kidney tumor (microcysts, oncocytoma, and kidney cell <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a>).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Drugs And Lithionite<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;The effect of the treatment can be affected if Lithionite is taken with certain other medicines.<\/p>\n\n\n\n<p>In particular, tell your doctor or pharmacist if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Non-steroidal anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;), e.g.&nbsp;indomethacin,&nbsp;diclofenac, meloxicam,&nbsp;ibuprofen, dexibuprofen, and&nbsp;naproxen&nbsp;(painkillers and anti-inflammatory drugs)<\/li><li>COX-2&nbsp;inhibitors, e.g.&nbsp;celecoxib, rofecoxib, parecoxib, and etoricoxib (analgesics and anti-inflammatory drugs)<\/li><li>ACE inhibitors, e.g.&nbsp;enalapril&nbsp;and lisinopril (antihypertensive drugs)<\/li><li>Angiotensin&nbsp;II&nbsp;receptor&nbsp;antagonist&nbsp;s, e.g.&nbsp;losartan&nbsp;(antihypertensive drug)<\/li><li>Aciclovir (antiviral medicine)<\/li><li>Neuroleptics, e.g.&nbsp;haloperidol&nbsp;and thioridazine (antipsychotic drugs)<\/li><li>Selective serotonin reuptake inhibitors (&nbsp;SSRIs&nbsp;), e.g.&nbsp;fluoxetine&nbsp;and fluvoxamine (antidepressants)<\/li><li>Venlafaxine&nbsp;(an antidepressant)<\/li><li>Sibutramine (weight loss medicine)<\/li><li>Sumatriptan (anti-migraine&nbsp;medicine&nbsp;)<\/li><li>Calcitonin (the drug that regulates calcium metabolism)<\/li><li>Metronidazole (drug against anaerobic bacteria and parasites)<\/li><li>Thiazides&nbsp;and loop&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;)<\/li><li>L-methyldopa (antihypertensive drug)<\/li><li>Carbamazepine (drugs against&nbsp;epilepsy&nbsp;)<\/li><li>Muscle relaxants<\/li><li>Xanthine derivatives, e.g.&nbsp;theophylline (a drug that dilates the trachea) and caffeine<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding And Fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>There is a risk of fetal harm.&nbsp;Do not use Lithionit during pregnancy except on certain&nbsp;prescribed&nbsp;by a doctor.<\/p>\n\n\n\n<p>The following symptoms may occur in newborns of mothers who have <strong>Lithionite uses <\/strong>during the last trimester (the last three months of pregnancy): <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tremors<\/li><li>Muscle stiffness and\/or weakness<\/li><li>Drowsiness<\/li><li>Anxiety<\/li><li>Difficulty breathing<\/li><li>Difficulty eating<\/li><\/ul>\n\n\n\n<p>If your child has any of these symptoms, you may need to consult a doctor.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Lithium passes into breast milk and there is a risk that the baby will be affected.&nbsp;Breast-feeding should therefore be avoided during treatment with Lithionite.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Lithium should not be given to children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>During treatment with Lithionite, the ability to concentrate and react may be impaired.&nbsp;You should therefore know how the treatment affects you before performing anything that requires sharpened attention (for example, driving a car or performing precision work).<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Lithionite<\/h2>\n\n\n\n<p><strong><em>Lithionite uses<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/li><li><strong>Lithionit dosering<\/strong> one is determined by the doctor who adjusts it individually for you.&nbsp;Dose&nbsp;one can vary quite a bit from one patient to another.&nbsp;Dose&nbsp;one is determined after repeated determination of the lithium concentration in the blood.&nbsp;This requires regular blood tests, usually every 2-3 months throughout the treatment period.<\/li><li><em><strong>The usual&nbsp;dosage&nbsp;for preventive treatment:<\/strong><\/em><ul><li>Initially&nbsp;1 tablet morning and evening.&nbsp;After one week of treatment, the concentration of lithium in the blood is measured.&nbsp;Based on this value, the doctor determines the continued&nbsp;dosage.<\/li><\/ul><\/li><li><em><strong>The usual&nbsp;dosage&nbsp;in the treatment of manic conditions:<\/strong><\/em><ul><li>Initially,&nbsp;2 tablets 4 times daily for a few days, then the&nbsp;dose is&nbsp;adjusted&nbsp;based on the blood test value.<\/li><\/ul><\/li><li><em>Never&nbsp;change the dosage&nbsp;<\/em>without consulting your doctor.&nbsp;Take the tablets at fixed times according to your doctor&#8217;s&nbsp;prescription<em>.<\/em><\/li><li><em>The tablets should be swallowed whole.&nbsp;<\/em>To reduce the risk of&nbsp;side effects&nbsp;in the gastrointestinal tract, Lithionite can be taken with a meal.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Lithionite Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Very common Lithionite side effects (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Renal&nbsp;diabetes insipidus&nbsp;(simultaneous increase in thirst and urine output)<\/li><li>Weight gain (avoid high-calorie drinks)<\/li><li>Trembling hand<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased amount of urine<\/li><li>Increased thirst<\/li><li>Fluid retention (edema)<\/li><li>Feeling tired in arms and legs<\/li><li>Diarrhea<\/li><li>Nausea and stomach <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> (especially during the first weeks)<\/li><li>Acne-like rash<\/li><li>ECG&nbsp;changes<\/li><li>Effect on thyroid function, e.g.&nbsp;goiter<\/li><li>Impaired ability to concentrate and react<\/li><li>Reversible&nbsp;leukocytosis&nbsp;(temporary increase in&nbsp;white blood cells&nbsp;)<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle weakness<\/li><li>Transient Parkinson&#8217;s-like symptoms<\/li><li>Psoriasis&nbsp;or worsening&nbsp;psoriasis<\/li><li>ECG&nbsp;-f\u00f6r\u00e4ndringar of severe type<\/li><li>Headache<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/fatigue-syndrome\/\">Fatigue<\/a> (especially during the first weeks)<\/li><li>Dry mouth<\/li><li>Hyperparathyroidism (overproduction of parathyroid hormone)<\/li><li>Malignant neuroleptic syndrome (mainly in combination with&nbsp;neuroleptics&nbsp;), a severe condition with symptoms such as <ul><li>High fever<\/li><li>Excessive sweating<\/li><li>Decreased level of consciousness<\/li><li>Stiff muscles <\/li><li>Benign or malignant kidney tumors (with long-term treatment)<\/li><\/ul><\/li><li>Impaired renal function (with long-term treatment) including&nbsp;renal failure<\/li><li>Rash on the skin or mucous membranes (lichenoid drug reaction)<\/li><li>Hair loss<\/li><\/ul>\n\n\n\n<p>Many&nbsp;side effects&nbsp;occur at the beginning of treatment, such as <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thirst<\/li><li>Diarrhea<\/li><li>Fatigue<\/li><li>Trembling<\/li><\/ul>\n\n\n\n<p>They often disappear on their own after a while or can be remedied.&nbsp;If they become too troublesome, consult a doctor.&nbsp;Some patients also experience transient muscle fatigue.&nbsp;Stomach problems can be alleviated by taking the tablets with meals.<\/p>\n\n\n\n<p>Weight gain is not uncommon and it is therefore important to pay attention to calorie intake and to watch out for calorie-rich drinks.&nbsp;Thyroid,&nbsp;parathyroid&nbsp;and renal function should be checked by regular sampling.<\/p>\n\n\n\n<p>See also section &#8220;If you have taken too much Lithionite&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"> How To Store Lithionite<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the blister, label, or carton after EXP or EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Do not store above 25 \u00b0 C.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Pack And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is anhydrous lithium sulfate equivalent to 42 mg (6 mmol) lithium.<\/li><li>The other ingredients are polyacrylate, hypromellose, and magnesium stearate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Lithionite 42 mg&nbsp;prolonged-release tablets&nbsp;are white, round&nbsp;prolonged-release tablets<\/li><li><em>Blister Pack:<\/em>&nbsp;100 and 250&nbsp;prolonged-release tablets<\/li><li><em>Glass jar:<\/em>&nbsp;500&nbsp;prolonged-release tablets&nbsp;are<\/li><li>Not all pack sizes may be marketed<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Lithionite is a global brand name for lithium used to feast and control episodes of obsession in people with bipolar disorder. Lithium is in a class of medicines called antimanic mechanisms, which decrease abnormal activity in the brain.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15579],"tags":[16103,16097,16098,16102,16101,16092,16096,16095,16099,16093,16100,16094],"class_list":["post-16838","post","type-post","status-publish","format-standard","hentry","category-medicines","category-l","tag-benefits-of-lithionite","tag-benefits-of-lithium-sulfate","tag-lithionite","tag-lithionite-side-effects","tag-lithionite-tablet","tag-lithium-sulfate","tag-lithium-sulfate-side-effects","tag-lithium-sulfate-tablet","tag-what-is-lithionite","tag-what-is-lithium-sulfate","tag-what-lithionite-is-used-for","tag-what-lithium-sulfate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=16838"}],"version-history":[{"count":74,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16838\/revisions"}],"predecessor-version":[{"id":38195,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16838\/revisions\/38195"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=16838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=16838"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=16838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}