{"id":16412,"date":"2021-12-07T10:05:22","date_gmt":"2021-12-07T10:05:22","guid":{"rendered":"https:\/\/zeepedia.com\/?p=16412"},"modified":"2021-12-08T09:32:26","modified_gmt":"2021-12-08T09:32:26","slug":"lergigan-3","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/lergigan-3\/","title":{"rendered":"Lergigan &#8211; Promethazine hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>Lergigan mite 5 mg, Lergigan 25 mg, Lergigan forte 50 mg&nbsp;film-coated tablets<br>promethazine hydrochloride<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Lergigan is and what it is used for<\/h2>\n\n\n\n<p>Lergigan contains promethazine and belongs to the group of\u00a0antihistamines.<\/p>\n\n\n\n<p>Lergigan blocks the effect of\u00a0histamine, a substance that is found in the body&#8217;s\u00a0tissues\u00a0and which, among other things, triggers\u00a0itching\u00a0in allergic reactions.\u00a0Like many histamine blocking substances, Lergigan also has a calming effect.\u00a0Lergigan is not addictive.<\/p>\n\n\n\n<p>Lergigan is used against:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tension and anxiety in nervous disorders.<\/li><li>Alcohol abuse.<\/li><li>Sleep disorders.<\/li><li>Severe anxiety and as a sedative before surgery and dental procedures.<\/li><li>Motion sickness, such as seasickness.<\/li><li>Skin itching and&nbsp;allergies&nbsp;.<\/li><li>Nausea and dizziness.<\/li><li>Excessive elation.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Lergigan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Lergigan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to prometazine or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Lergigan:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you suffer from an enlarged&nbsp;prostate<\/li><li>if you suffer from narrowing of the urethra<\/li><li>if you suffer from narrowing of the lower&nbsp;gastrointestinal tract&nbsp;and&nbsp;duodenum&nbsp;(pyloroduodenal&nbsp;obstruction&nbsp;)<\/li><li>if you have jaundice (&nbsp;hepatitis&nbsp;)<\/li><li>if you have&nbsp;myasthenia gravis&nbsp;(severe muscle weakness)<\/li><li>if you suffer from cardiovascular disease or changes in heart rhythm<\/li><li>if you have a risk of cerebral haemorrhage (&nbsp;stroke&nbsp;)<\/li><\/ul>\n\n\n\n<p>Due to\u00a0dry mouth\u00a0(which is a common side effect), there is a risk of tooth and oral mucosal damage, especially with prolonged use.\u00a0You should therefore brush your teeth thoroughly with fluoride toothpaste twice daily.<\/p>\n\n\n\n<p>Treatment with Lergigan can cause problems for contact lens wearers due to reduced tear flow.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Lergigan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This also applies to over-the-counter medicines and herbal medicines.<\/p>\n\n\n\n<p>Lergigan may affect or be affected if taken concomitantly with certain other medicinal substances against:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>arrhythmias in the heart (eg flecainide and&nbsp;amiodarone&nbsp;)<\/li><li>certain&nbsp;antibiotics&nbsp;(moxifloxacin and erythromycin)<\/li><li>pain conditions (eg&nbsp;methadone&nbsp;)<\/li><li>malaria drug (meflokin)<\/li><li>intestinal disease (eg cisapride)<\/li><li>mental disorders (eg lithium and&nbsp;neuroleptics&nbsp;such as&nbsp;haloperidol&nbsp;, clozapine and&nbsp;risperidone&nbsp;)<\/li><li>depression (&nbsp;tricyclic antidepressants&nbsp;)<\/li><li>anxiety (eg&nbsp;diazepam&nbsp;)<\/li><\/ul>\n\n\n\n<p>Avoid concomitant treatment with certain diuretics (thiazide diuretics), as these may reduce the level of potassium in the blood and thus increase the risk of arrhythmias in the heart.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lergigan with food, drink and alcohol<\/h2>\n\n\n\n<p>Concomitant use of alcohol and central depressants should be avoided due to the risk of the enhanced effect of Lergigan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em><strong>Pregnancy<\/strong><\/em><\/p>\n\n\n\n<p>No adverse effects on the fetus have been demonstrated.<\/p>\n\n\n\n<p><em><strong>Breast-feeding<\/strong><\/em><\/p>\n\n\n\n<p>It is not known if promethazine hydrochloride passes into breast milk.\u00a0Therefore, consult a physician before regular use during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>During treatment with Lergigan, the ability to react may be reduced.&nbsp;This should be taken into account when sharper attention is required, eg when driving a car.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lergigan mite contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Lergigan<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dose&nbsp;one is determined by the physician, who adjusts it individually for each patient.&nbsp;The usual&nbsp;dose&nbsp;of tablets is:<\/p>\n\n\n\n<p><em>Nervous conditions:<\/em>&nbsp;Adults: 5-50 mg 1-3 times daily.&nbsp;Children: 2-5 years: 5 mg 1-3 times daily, children 5-12 years: 10 mg 1-3 times daily.<\/p>\n\n\n\n<p><em>Severe anxiety and hyperactivity:<\/em>&nbsp;Adults: 25-50 mg, up to 400-500 mg per day.<\/p>\n\n\n\n<p><em>Sleep disorders:<\/em>&nbsp;Adults: 25-50 mg at night.&nbsp;Children 2-5 years: 5-20 mg at night, children 5-12 years: 20-25 mg at night.&nbsp;Sometimes the medication is interrupted every three or four nights.<\/p>\n\n\n\n<p><em>Motion sickness:<\/em>\u00a0Adults: 25 mg 1-2 hours before the trip or the evening before the trip.\u00a0If necessary, two more\u00a0doses can\u00a0be taken in one day.<\/p>\n\n\n\n<p>Children: 2-5 years: 5 mg 1-2 hours before the trip or the evening before the trip.\u00a0If necessary, two more\u00a0doses can\u00a0be taken in one day.<\/p>\n\n\n\n<p>Children 5-12 years: 10 mg 1-2 hours before the trip or the evening before the trip.\u00a0If necessary, two more\u00a0doses can\u00a0be taken in one day.<\/p>\n\n\n\n<p><em>Allergic conditions:<\/em>&nbsp;Adults: 25 (-50) mg at night.&nbsp;Children 2-5 years: 5 mg 1-3 times daily, children 5-12 years: 10 mg 1-3 times daily.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Lergigan can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10<\/em>\u00a0people\u00a0<em>)<\/em>\u00a0: Drowsiness.\u00a0Dry mouth.\u00a0When Lergigan is taken at night, you may feel a little drowsy the next morning.\u00a0This disappears after a few days of treatment.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>: Difficulty disposing of water.\u00a0Constipation.\u00a0Difficulties for the eye to switch between near and far vision.\u00a0Reduced tear flow.<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em>\u00a0Jaundice without signs of liver damage.\u00a0Effects on heart rate, irregular heartbeat, and\u00a0ECG\u00a0changes associated with it.\u00a0Cardiac arrest.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Lergigan<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>The medicine should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><em>The active substance is<\/em>&nbsp;: promethazine hydrochloride 5 mg, 25 mg and 50 mg respectively.<\/li><li><em>Other ingredients are:<\/em>&nbsp;titanium dioxide (E171),&nbsp;glycerol&nbsp;, vanilla flavor, magnesium stearate, sorbitan oleate, anhydrous&nbsp;colloidal&nbsp;silica, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, ethyl cellulose, hydroxypropyl cellulose, macrogol 8000, crospovidone (not included in Lergigan&nbsp;mite&nbsp;).&nbsp;Lergigan&nbsp;mite&nbsp;also contains sodium starch glycolate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p><em>Lergigan&nbsp;mite&nbsp;5 mg:<\/em><\/p>\n\n\n\n<p>White, round, film-coated tablet, cupped, with embossing LM within arches, diameter 6 mm.&nbsp;30 pcs and 100 pcs in plastic jars with child-resistant lids.<\/p>\n\n\n\n<p><em>Lergigan 25 mg:<\/em><\/p>\n\n\n\n<p>White, round, film-coated tablet, cupped, with embossing LE in frames, diameter 6 mm.&nbsp;30 pcs and 100 pcs in plastic jars with child-resistant lids.<\/p>\n\n\n\n<p><em>Lergigan&nbsp;forte&nbsp;50 mg:<\/em><\/p>\n\n\n\n<p>White, round, film-coated tablet, cupped, with embossing LF within arches, diameter 6 mm.&nbsp;100 pcs in plastic jars with child-resistant lids.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p>Meda AB<\/p>\n\n\n\n<p>Box 906<\/p>\n\n\n\n<p>170 09 Solna<\/p>\n\n\n\n<p>Phone: 08-630 19 00<\/p>\n\n\n\n<p>Email: info@meda.se<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lergigan contains promethazine and belongs to the group of antihistamines .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15579],"tags":[15593,15587,15588,15592,15591,15582,15586,15585,15589,15583,15590,15584],"class_list":["post-16412","post","type-post","status-publish","format-standard","hentry","category-medicines","category-l","tag-benefits-of-lergigan","tag-benefits-of-promethazine-hydrochloride","tag-lergigan","tag-lergigan-side-effects","tag-lergigan-tablet","tag-promethazine-hydrochloride","tag-promethazine-hydrochloride-side-effects","tag-promethazine-hydrochloride-tablet","tag-what-is-lergigan","tag-what-is-promethazine-hydrochloride","tag-what-lergigan-is-used-for","tag-what-promethazine-hydrochloride-is-usd-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16412","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=16412"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16412\/revisions"}],"predecessor-version":[{"id":16433,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16412\/revisions\/16433"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=16412"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=16412"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=16412"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}