{"id":16408,"date":"2021-12-07T10:02:46","date_gmt":"2021-12-07T10:02:46","guid":{"rendered":"https:\/\/zeepedia.com\/?p=16408"},"modified":"2022-10-21T17:30:11","modified_gmt":"2022-10-21T17:30:11","slug":"lergigan-comp","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/lergigan-comp\/","title":{"rendered":"Lergigan Comp &#8211; Prometazine Hydrochloride\/Caffeine\/Ephedrine Sulphate | Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p>10 mg \/ 50 mg \/ 10 mg&nbsp;tablet<br>Prometazine Hydrochloride \/ Caffeine \/ Ephedrine sulphate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Lergigan Comp Is And What It Is Used For<\/h2>\n\n\n\n<p><strong>Lergigan Comp English<\/strong> contains promethazine, caffeine, and&nbsp;ephedrine&nbsp;and belongs to the group of&nbsp;antihistamines.&nbsp;Promethazine blocks the effect of&nbsp;histamine, a substance found in the body&#8217;s&nbsp;tissues&nbsp;that, among other things, triggers&nbsp;itching&nbsp;in allergic reactions.&nbsp;Promethazine means that Lergigan comp also has a calming effect.&nbsp;Ephedrine&nbsp;and caffeine enhance the effects of <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/motion-sickness\/\">motion sickness<\/a> and pregnancy nausea.<\/p>\n\n\n\n<p>Lergigan comp is used against:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tension and <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/anxiety-strong-feelings-of-worry\/\">anxiety<\/a> in nervous disorders.<\/li><li>Alcohol abuse and drug addiction.<\/li><li><a href=\"https:\/\/amzn.to\/3VQLpYI\" rel=\"noopener\">Sleep disorders<\/a>.<\/li><li>Severe anxiety and as a sedative before surgery and dental procedures.<\/li><li>Motion sickness, such as seasickness.<\/li><li>Skin itching and\u00a0allergies.<\/li><li>Nausea and dizziness<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before Using Lergigan Comp<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"200\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/10\/lergigan-Comp-300x200.jpg\" alt=\"lergigan Comp\" class=\"wp-image-27493\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/10\/lergigan-Comp-300x200.jpg 300w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/10\/lergigan-Comp-1024x682.jpg 1024w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/10\/lergigan-Comp-768x512.jpg 768w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/10\/lergigan-Comp.jpg 1136w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Lergigan Comp<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to prometazine, caffeine, ephedrine sulphate, or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Lergigan comp as <em>lergigan side effects<\/em> vary person to person  :<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you suffer from an enlarged\u00a0prostate.<\/li><li>If you suffer from narrowing of the urethra.<\/li><li>If you suffer from narrowing of the lower\u00a0gastrointestinal tract\u00a0and\u00a0duodenum\u00a0(pyloroduodenal\u00a0obstruction\u00a0).<\/li><li>If you have <a href=\"https:\/\/zeepedia.com\/diseases\/hepatitis-a-infectious-jaundice\/\">jaundice<\/a> (\u00a0hepatitis\u00a0).<\/li><li>If you have\u00a0myasthenia gravis\u00a0(severe muscle weakness).<\/li><li>If you suffer from cardiovascular disease or changes in heart rhythm.<\/li><li>If you have a risk of cerebral haemorrhage (\u00a0stroke\u00a0).<\/li><li>If you have high\u00a0blood pressure.<\/li><li>Due to\u00a0dry mouth\u00a0(which is a common side effect), there is a risk of tooth and oral mucosal damage, especially with prolonged use.\u00a0You should therefore brush your teeth thoroughly with fluoride toothpaste twice daily.<\/li><\/ul>\n\n\n\n<p>Treatment with <em>Lergigan Comp English<\/em> can cause problems for contact lens wearers due to reduced tear flow.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Drugs And Lergigan Comp<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This also applies to over-the-counter medicines and herbal medicines.<\/p>\n\n\n\n<p>Lergigan Comp English may affect or be affected if taken at the same time as certain other medicinal substances against:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cardiac drugs are given directly into the bloodstream (eg\u00a0adenosine\u00a0).<\/li><li>Infection\u00a0(eg\u00a0ciprofloxacin\u00a0, norfloxacin).<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">Depression<\/a> (\u00a0tricyclic antidepressants\u00a0).<\/li><li>Allergic nasal congestion (eg phenylpropanolamine).<\/li><li>Epilepsy\u00a0(eg carbamazepine).<\/li><li>Certain psychiatric conditions (eg lithium and\u00a0neuroleptics\u00a0such as\u00a0haloperidol, clozapine, and\u00a0risperidone\u00a0).<\/li><li>Anxiety (eg\u00a0diazepam).<\/li><li>High\u00a0blood pressure\u00a0(eg\u00a0beta-blockers\u00a0and\u00a0alpha-blockers).<\/li><li>Arrhythmias in the heart (eg flecainide and\u00a0amiodarone).<\/li><li>Certain\u00a0antibiotics\u00a0(moxifloxacin and erythromycin).<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">Pain<\/a> conditions (eg\u00a0methadone).<\/li><li>Malaria drug (meflokin).<\/li><li>Intestinal disease (eg cisapride).<\/li><\/ul>\n\n\n\n<p>Avoid concomitant treatment with certain diuretics (thiazide diuretics), as these may reduce the level of potassium in the blood and thus increase the risk of arrhythmias in the heart.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lergigan Comp With Food, Drink, And Alcohol<\/h2>\n\n\n\n<p>Concomitant use of alcohol or central suppressants should be avoided due to the risk of enhanced drug effects.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lergigan Comp Pregnancy, Breastfeeding, and Fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Lergigan Comp pregnancy effects. <\/em><\/p>\n\n\n\n<p><em>Promethazine and&nbsp;ephedrine<\/em><\/p>\n\n\n\n<p>No known hazards during use.<\/p>\n\n\n\n<p><em>Caffeine<\/em><\/p>\n\n\n\n<p>Pregnant women are advised to limit their caffeine intake as available data suggest a possible risk to the fetus.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Caffeine passes into breast milk but probably does not affect breastfed babies.&nbsp;No information is available on promethazine and&nbsp;ephedrine&nbsp;passing into breast milk.&nbsp;Therefore, consult a physician before regular use during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines:<\/h2>\n\n\n\n<p>Lergigan comp side effects during treatment:<\/p>\n\n\n\n<p>During treatment with Lergigan comp, the ability to react may be reduced.&nbsp;This should be taken into account when sharper attention is required, eg when driving a car.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.<\/p>\n\n\n\n<p>\u00a0Descriptions of <em>Lergigan comp side effects<\/em> and effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lergigan Comp Contains Sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How To Use Lergigan Comp<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/li><li>Dose&nbsp;one is determined by the physician, who adjusts it individually for each patient.&nbsp;The usual&nbsp;dose&nbsp;is: 1 tablet 1-2 times daily.<\/li><li>Nausea and vomiting can be avoided if the tablets are taken with a meal.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Lergigan Side Effects<\/h2>\n\n\n\n<p><span style=\"text-decoration: underline;\">Lergigan side effects<\/span><\/p>\n\n\n\n<p>Like all medicines, Lergigan comp can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):&nbsp;<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dry mouth<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness<\/li><li>Headache<\/li><li>Difficulty <\/li><li>Throwing water<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/constipation\/\">Constipation<\/a><\/li><li>Difficulties for the eye to switch between near and far vision<\/li><li>Reduced tear flow<\/li><li>Nausea<\/li><li>Vomiting<\/li><li>Sweating<\/li><li>Thirst<\/li><li>Palpitations<\/li><li>Muscle weakness<\/li><li>Tremors<\/li><li>Anxiety<\/li><li>Ringing in the ears<\/li><li>Flicker of the eyes may occur at high&nbsp;doses<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Jaundice without signs of liver damage<\/li><li>Effects on heart rhythm<\/li><li>Irregular heartbeat<\/li><li>ECG&nbsp;changes associated with it<\/li><li>Cardiac arrest<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Lergigan Comp<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton.\u00a0The expiration date is the last day of the specified month.<\/li><li>The medicine should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines no longer required.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Pack And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<p>The active substances are:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>&nbsp;Promethazine hydrochloride 10 mg.<\/li><li>Caffeine 50 mg and&nbsp;ephedrine&nbsp;10 mg.<\/li><\/ol>\n\n\n\n<p>The other ingredients are:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>&nbsp;Titanium dioxide (E171)<\/li><li>Glycerol&nbsp;<\/li><li>Vanilla aroma<\/li><li>Magnesium stearate<\/li><li>Anhydrous&nbsp;colloidal&nbsp;silica<\/li><li>Calcium hydrogen phosphate dihydrate<\/li><li>Microcrystalline cellulose<\/li><li>Ethylcellulose<\/li><li>Hydroxypropylcellulose<\/li><li>Macrogol<\/li><li>Sodium starch glycolate<\/li><li>Sorbitanoleate.<\/li><\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">What the Medicine Looks Like And Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Lergigan comp film-coated tablets are 9 mm in diameter, white and round, and cupped with embossing LC within arches.<\/li><li>Plastic jar with child-resistant lid: 30 tablets.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p>Meda AB<\/p>\n\n\n\n<p>Box 906<\/p>\n\n\n\n<p>170 09 Solna<\/p>\n\n\n\n<p>Phone: 08-630 19 00<\/p>\n\n\n\n<p>Email: <a href=\"mailto:info@meda.se\">info@meda.se<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lergigan Comp is an H1 antagonist with anticholinergic, tranquilizer, antiemetic effects, and certain local numbing properties. It is used as an antiemetic or to stop motion sickness.<\/p>\n","protected":false},"author":2,"featured_media":27493,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2200,15579],"tags":[15600,11915,15604,15595,15599,15598,15601,11917,15606,11916,15605,15596,15602,15597,15603],"class_list":["post-16408","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicines","category-l","tag-benefits-of-lergigan-comp","tag-caffeine","tag-ephedrine-sulphate","tag-lergigan-comp","tag-lergigan-comp-side-effects","tag-lergigan-comptablet","tag-prometazine-hydrochloride","tag-what-caffeine-is-used-for","tag-what-ephedrine-sulphate-is-used-for","tag-what-is-caffeine","tag-what-is-ephedrine-sulphate","tag-what-is-lergigan-comp","tag-what-is-prometazine-hydrochloride","tag-what-lergigan-comp-is-used-for","tag-what-prometazine-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16408","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=16408"}],"version-history":[{"count":89,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16408\/revisions"}],"predecessor-version":[{"id":27684,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16408\/revisions\/27684"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/27493"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=16408"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=16408"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=16408"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}