{"id":16320,"date":"2021-12-06T09:58:35","date_gmt":"2021-12-06T09:58:35","guid":{"rendered":"https:\/\/zeepedia.com\/?p=16320"},"modified":"2021-12-09T07:13:07","modified_gmt":"2021-12-09T07:13:07","slug":"laxiriva","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/laxiriva\/","title":{"rendered":"Laxiriva &#8211; macrogol 3350 \/ sodium chloride \/ sodium bicarbonate \/ potassium chloride uses, dose and side effects"},"content":{"rendered":"\n<p>macrogol 3350 \/ sodium chloride \/ sodium bicarbonate \/ potassium chloride&nbsp;powder for&nbsp;oral&nbsp;solution<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Laxiriva is and what it is used for<\/h2>\n\n\n\n<p>Laxiriva is a\u00a0laxative\u00a0for the temporary treatment of constipation in adults, adolescents, and the elderly.\u00a0It is not recommended for children under 12 years.<\/p>\n\n\n\n<p>Macrogol 3350 (one of the active substances in the medicine) softens your stools, makes it easier to have stools, and relieves constipation.\u00a0The salts contained in the product helps maintain normal\u00a0sodium,\u00a0potassium,\u00a0and fluid balance during treatment.<\/p>\n\n\n\n<p>Macrogol 3350 contained in Laxiriva may also be approved for the treatment of other diseases not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Laxiriva<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Laxiriva<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to macrogol 3350, sodium chloride, sodium bicarbonate, potassium chloride or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if your intestinal wall is perforated (a wound in the intestinal wall).<\/li><li>if you have intestinal obstruction (so-called intestinal obstruction,&nbsp;ileus&nbsp;).<\/li><li>if you have a severe&nbsp;inflammatory&nbsp;bowel disease, such as&nbsp;ulcerative colitis&nbsp;,&nbsp;Crohn&#8217;s disease&nbsp;or toxic megacolon.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>If you develop\u00a0side effects\u00a0such as swelling, shortness of breath, fatigue, dehydration (symptoms include increased thirst,\u00a0dry mouth,\u00a0and weakness), or heart problems, you should stop taking Laxiriva and contact your doctor immediately.<\/p>\n\n\n\n<p>If you experience sudden abdominal pain or rectal bleeding while taking Laxiriva for bowel cleansing, you should contact a doctor immediately or seek medical attention.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Do not give this medicine to children under 12 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Laxiriva<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The effect of certain drugs, e.g.&nbsp;epilepsy medications, may be weaker than normal during treatment with Laxiriva.&nbsp;Therefore, other medicines should not be taken orally within one hour before and one hour after taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Laxiriva can be used during pregnancy and lactation.\u00a0If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>This medicine does not affect your ability to drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Laxiriva contains sodium, sorbitol and potassium<\/h2>\n\n\n\n<p>This medicine contains 188 mg of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per\u00a0sachet.\u00a0This corresponds to 9.4% of the highest recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<p>When used to treat constipation, the highest recommended daily\u00a0dose\u00a0of this medicine is 564 mg of\u00a0sodium\u00a0(found in table salt).\u00a0This corresponds to 28.2% of the highest recommended daily intake of\u00a0sodium.<\/p>\n\n\n\n<p>Consult a physician or pharmacist if you need 3 sachets or more daily for an extended period, especially if you have been prescribed a low-salt (sodium-poor) diet.<\/p>\n\n\n\n<p>This medicine contains 0.6 mmol (or 24.4 mg)\u00a0potassium\u00a0per\u00a0sachet.\u00a0This should be considered by patients with\u00a0impaired\u00a0renal function or patients on a low-potassium diet.<\/p>\n\n\n\n<p>The lemon and lime aromas in this medicine contain 0.8 mg sorbitol (E420) per\u00a0sachet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Laxiriva<\/h2>\n\n\n\n<p>Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Constipation<\/strong><\/p>\n\n\n\n<p>A\u00a0dose\u00a0of Laxiriva is a\u00a0sachet\u00a0to be dissolved in 125 ml (half a glass) of water.\u00a0Take this\u00a0dose\u00a01-3 times daily according to the severity of constipation.<\/p>\n\n\n\n<p>The treatment with this drug usually lasts for about 2 weeks.\u00a0If you need to take this medicine for a long time, see a doctor.\u00a0If the constipation is caused by a disease, e.g.\u00a0Parkinson&#8217;s disease\u00a0or\u00a0multiple sclerosis, or if you are taking medicines that cause constipation, your doctor may recommend that you take this medicine for more than 2 weeks.\u00a0If you need to take this medicine for a long time, see a doctor.\u00a0With long-term treatment, the\u00a0dose\u00a0can\u00a0usually be reduced to 1 or 2 sachets daily.<\/p>\n\n\n\n<p><strong>Mixing the solution<\/strong><br>Open a&nbsp;sachet&nbsp;and pour the contents into a drinking glass.&nbsp;Pour in about 125 ml (half a glass) of water.&nbsp;Stir well until all the powder has dissolved and the solution is clear or slightly cloudy, then drink the solution.<\/p>\n\n\n\n<p>This medicine should be taken orally.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children<\/h2>\n\n\n\n<p>Do not give this medicine to children under 12 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Laxiriva than you should<\/h2>\n\n\n\n<p>This can cause severe stomach pain and bloating vomiting (nausea), or diarrhea.\u00a0Severe diarrhea can lead to dehydration.\u00a0If this happens, stop taking this medicine and drink plenty of fluids.\u00a0If you have any further questions, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>If you get any of the following\u00a0side effects, stop taking Laxiriva and contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>signs of&nbsp;allergy&nbsp;, such as rash,&nbsp;itching&nbsp;, redness of the skin, shortness of breath, difficulty breathing or swelling of the face, lips, tongue or throat<\/li><li>signs of changes in the body&#8217;s fluid or electrolyte balance, such as swelling (mainly in the ankles), feeling of weakness, dehydration, increasing fatigue or increased thirst in combination with headache.&nbsp;These symptoms may be a sign that the potassium levels in the blood are higher or lower than normal.<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swollen hands, feet or ankles<\/li><li>headache<\/li><li>indigestion, stomach pain or rumbling stomach<\/li><li>bloating, flatulence, nausea or vomiting<\/li><li>tenderness around the rectal opening<\/li><li>diarrhea (when you start taking this medicine).<\/li><li>change in the body&#8217;s fluid or electrolyte levels (low level of&nbsp;potassium&nbsp;, low level of&nbsp;sodium&nbsp;).<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;are usually alleviated if you reduce the&nbsp;dose&nbsp;of Laxiriva.<\/p>\n\n\n\n<p>The frequency of occurrence of these&nbsp;side effects&nbsp;is not known (can not be calculated from the available data).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Laxiriva<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and sachet after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>The prepared solution with Laxiriva can be stored covered in a refrigerator (2 \u00b0 C \u2013 8\u00a0<sup>\u00b0<\/sup>\u00a0C).\u00a0The solution should be used within 24 hours.\u00a0Any remaining solution should be discarded 24 hours after the powder has dissolved.<\/p>\n\n\n\n<p>Do not use this medicine if you notice that any of the sachets are damaged.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substances in a&nbsp;sachet&nbsp;are:<\/p>\n\n\n\n<p>macrogol 3350 13.125 g<\/p>\n\n\n\n<p>sodium chloride 350.7 mg<\/p>\n\n\n\n<p>sodium bicarbonate 178.5 mg<\/p>\n\n\n\n<p>potassium chloride 46.6 mg<\/p>\n\n\n\n<p>The other ingredients are\u00a0colloidal\u00a0anhydrous silica, saccharin sodium, orange aroma (orange aroma contains: flavoring substances and preparations, maltodextrin, acacia gum [E414], alpha-tocopherol [E307]), and lemon and lime aromas (lemon and lemon aroma, natural, lemon aroma, natural lime aroma powder, maltodextrin, mannitol [E421], gluconolactone [E575], sorbitol [E420], acacia rubber [E414],\u00a0colloidal\u00a0anhydrous silica [E551]).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Laxiriva is a white crystalline powder.<\/p>\n\n\n\n<p>The sachet consists of PAP \/ ALU \/ PE.<\/p>\n\n\n\n<p>Each\u00a0sachet\u00a0contains 13.8 g of powder and is supplied in cardboard boxes of 2, 6, 8, 10, 20, 30, or 50 sachets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen, Denmark<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Salutas Pharma GmbH, Otto-von-Guericke-Allee 1, 39179 Barleben, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Laxiriva is a laxative for the temporary treatment of constipation in adults, adolescents and the elderly. It is not recommended for children under 12 years.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15579],"tags":[15578,15574,15577,15419,4230,14699,11616,15575,15576],"class_list":["post-16320","post","type-post","status-publish","format-standard","hentry","category-medicines","category-l","tag-benefits-of-laxiriva","tag-laxiriva","tag-laxiriva-side-effects","tag-macrogol-3350","tag-potassium-chloride","tag-sodium-bicarbonate","tag-sodium-chloride","tag-what-is-laxiriva","tag-what-laxiriva-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=16320"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16320\/revisions"}],"predecessor-version":[{"id":16391,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16320\/revisions\/16391"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=16320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=16320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=16320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}