{"id":16198,"date":"2021-12-03T06:19:50","date_gmt":"2021-12-03T06:19:50","guid":{"rendered":"https:\/\/zeepedia.com\/?p=16198"},"modified":"2021-12-09T07:24:10","modified_gmt":"2021-12-09T07:24:10","slug":"lasix-retard","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/lasix-retard\/","title":{"rendered":"Lasix Retard &#8211; Furosemide uses, dose and side effects"},"content":{"rendered":"\n<p>30 mg and 60 mg&nbsp;hard&nbsp;prolonged-release&nbsp;capsule<br>furosemide, respectively<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Lasix Retard is and what it is used for<\/h2>\n\n\n\n<p>Lasix\u00a0Retard\u00a0is a\u00a0diuretic, a diuretic, which is used for fluid retention in the body&#8217;s\u00a0tissues\u00a0(\u00a0edema\u00a0) and high\u00a0blood pressure.\u00a0Lasix\u00a0Retard\u00a0inhibits the kidneys&#8217; ability to reabsorb water and salt, leading to increased urinary excretion.\u00a0Thus, the\u00a0edema\u00a0decreases or disappears.<\/p>\n\n\n\n<p>Furosemide\u00a0contained in Lasix\u00a0Retard\u00a0may also be approved for the treatment of other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Lasix Retard<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Lasix Retard<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;furosemide&nbsp;, related&nbsp;sulfonamides&nbsp;(eg antidiabetic drugs) or any of the other ingredients of this medicine (listed in section 6)<\/li><li>in severe liver or kidney disease<\/li><li>you are at risk of dehydration<\/li><li>you suffer from almost completely eliminated urine excretion<\/li><li>you suffer from very low&nbsp;potassium&nbsp;and sodium levels in your blood<\/li><li>you are breastfeeding (the active substance passes into breast milk)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Lasix&nbsp;Retard&nbsp;if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>your kidneys are not working well<\/li><li>you are taking heart medication that contains&nbsp;digoxin<\/li><li>you are on a strictly low-salt diet<\/li><li>you have difficulty emptying your bladder or if you suspect that there may be obstruction to your urine output<\/li><li>you have low&nbsp;blood pressure<\/li><li>you get sharp drops in blood pressure<\/li><li>you have&nbsp;diabetes<\/li><li>you have&nbsp;gout<\/li><li>you have low egg white levels in your blood.&nbsp;(If it occurs dose adjustment is required)<\/li><li>you have systemic lupus erythematosus (disease in which the body&#8217;s immune system attacks the body)<\/li><li>you are older, if you are taking other medicines that can lower&nbsp;your blood pressure&nbsp;, or if you have any other illness that carries a risk of lowering your&nbsp;blood pressure<\/li><\/ul>\n\n\n\n<p>If you suffer from vomiting, diarrhea, and heavy sweating, there may be an increased risk of disturbing the salt and electrolyte balance in the body.\u00a0There may then be a need to take an extra blood sample.\u00a0Contact your doctor if you feel unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Lasix Retard<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The effect of the treatment can be affected if this medicine and certain other medicines are taken at the same time, this also applies to over-the-counter medicines, natural medicines, or other natural products.\u00a0The treating physician, therefore, needs to be aware of such concomitant medication.<\/p>\n\n\n\n<p>The following drugs should be avoided during concomitant treatment with Lasix Retard:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>gentamicin (used for&nbsp;infections&nbsp;)<\/li><li>chloral hydrate (a kind of sleeping pill)<\/li><li>risperidone&nbsp;(used in schizophrenia, among others)<\/li><li>drugs known to adversely affect hearing such as certain&nbsp;antibiotics&nbsp;(&nbsp;aminoglycosides&nbsp;) and diuretics (ethacrynic acid)<\/li><\/ul>\n\n\n\n<p>The following medicines may be taken with Lasix&nbsp;Retard&nbsp;but may need to be dose-adjusted:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>ACE inhibitors&nbsp;and angiotensin II&nbsp;receptor&nbsp;blockers (used for high&nbsp;blood pressure,&nbsp;among other things&nbsp;)<\/li><li>medicines for high&nbsp;blood pressure<\/li><li>digitalis glycosides&nbsp;and other drugs that affect the rhythm of the heart<\/li><li>lithium (used in manic depressive illness)<\/li><li>NSAID-&nbsp;type&nbsp;anti-inflammatory&nbsp;and analgesic agents&nbsp;such as ibumetin and <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a><\/li><li>drugs known to adversely affect the kidneys<\/li><li>cephalosporins&nbsp;(used for&nbsp;infections&nbsp;)<\/li><li>sotalol (used for high&nbsp;blood pressure,&nbsp;among other things&nbsp;)<\/li><li>cisplatin (used in cancer)<\/li><li>sucralfate (used for&nbsp;stomach ulcers&nbsp;)<\/li><li>phenytoin&nbsp;(used in&nbsp;epilepsy&nbsp;)<\/li><li>ciclosporin A (used in organ transplantation)<\/li><li>methotrexate (used in cancers, among others)<\/li><li>drugs against&nbsp;diabetes<\/li><li>adrenaline&nbsp;(used in anesthetics and in&nbsp;hypersensitivity reactions&nbsp;)<\/li><li>norepinephrine&nbsp;(for low&nbsp;blood pressure&nbsp;)<\/li><li>curare-like muscle relaxants<\/li><li>theophylline (used in&nbsp;asthma&nbsp;)<\/li><li>corticosteroids&nbsp;(used for&nbsp;inflammation&nbsp;, among other things&nbsp;)<\/li><li>carbenoxolone (used for&nbsp;stomach ulcers&nbsp;)<\/li><li>large amounts of licorice<\/li><li>long-term use of&nbsp;laxatives<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>There is a risk that the fetus is affected.&nbsp;Therefore, always consult a doctor before using Lasix&nbsp;Retard&nbsp;during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>A breastfed baby may be affected.\u00a0Use therefore not Lasix\u00a0Retard\u00a0during lactation except on certain\u00a0prescriptions\u00a0from the doctor.\u00a0Breastfeeding mothers should be aware that the amount of milk may decrease.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Due to certain\u00a0side effects\u00a0(eg a sharp drop in blood pressure), the degree of alertness and reaction time can change to such an extent that it is not possible to drive motor vehicles or safely handle machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lasix Retard contains sucrose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Lasix Retard<\/h2>\n\n\n\n<p>Dose&nbsp;one is determined by the doctor who adapts it for you.&nbsp;Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;for adults is 1 capsule of 30 mg or 1 capsule of 60 mg daily, which is usually taken as a single dose in the morning.<\/p>\n\n\n\n<p><em>The capsules should be swallowed whole and with at least half a glass of liquid.<\/em><\/p>\n\n\n\n<p><strong>Instructions for use for plastic pipes<\/strong><\/p>\n\n\n\n<p>The plastic tube opens most easily if you squeeze it in the middle of the tube.\u00a0Place your thumb under the knurled edge on the side of the lid and move the lid upwards with a gentle movement.\u00a0If the lid does not come off immediately, move your thumb slightly to the side and try again.\u00a0(If you grab the lid and pull sharply upwards, the pipe can be difficult to open).<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19820429000027#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/sanofi\/Media\/Lasix20retard\/LasixRetardBild1.jpg\" alt=\"The picture shows how you can most easily open up the plastic pipe\" title=\"The picture shows how you can most easily open up the plastic pipe\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Lasix\u00a0Retard\u00a0can in very rare cases affect the white\u00a0blood cells\u00a0so that the\u00a0defense against\u00a0infection deteriorates.\u00a0If you get an\u00a0infection\u00a0with symptoms such as fever with severe general condition or fever with local infection symptoms such as sore throat\/pharynx\/mouth or urination problems, you should see a doctor as soon as possible so that a blood test can rule out a lack of\u00a0white blood cells\u00a0(\u00a0agranulocytosis\u00a0).\u00a0It is important that you then have information about your medication.<\/p>\n\n\n\n<p><em>Very common (more than 1 in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Disorders of the body&#8217;s salt balance or dehydration, especially in the elderly.&nbsp;Detected using blood tests.&nbsp;May cause symptoms such as fatigue, headache and dizziness.<\/li><li>Decreased blood volume, especially in the elderly, is detected with the help of a blood test.<\/li><li>Increased blood creatinine levels, which may be a sign of impaired kidney function.&nbsp;Detected using blood tests.<\/li><li>Increased levels of&nbsp;triglycerides&nbsp;in the blood (blood fats) which may increase the risk of atherosclerosis \/ increase the risk of cardiovascular disease.&nbsp;Detected using blood tests.<\/li><\/ul>\n\n\n\n<p><em>Common (more than 1 in 100):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Elevated uric acid levels in the blood, which can lead to&nbsp;gout&nbsp;.&nbsp;Gout&nbsp;can be experienced as sore and swollen joints.<\/li><li>Increased blood cholesterol (blood fats) which can increase the risk of atherosclerosis \/ increase the risk of cardiovascular disease.&nbsp;Detected using blood tests.<\/li><li>Increased urine volume.<\/li><li>Concentration of the blood, ie reduced amount of fluid in the blood, which gives increased concentration of blood components and can increase the risk of blood clots.&nbsp;Detected via blood test.&nbsp;May occur due to excessive&nbsp;diuretic&nbsp;effect.<\/li><li>Brain effects in users with impaired liver function.<\/li><li>Gout attacks.<\/li><\/ul>\n\n\n\n<p><em>Uncommon (more than 1 in 1000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea.<\/li><li>Hearing loss.<\/li><li>Decreased&nbsp;platelet count&nbsp;(&nbsp;platelets&nbsp;), which can cause bruising and bleeding.<\/li><li>Skin reactions such as&nbsp;itching&nbsp;,&nbsp;hives&nbsp;, blisters, flaking,&nbsp;redness&nbsp;and&nbsp;inflammation&nbsp;of the skin, slight bleeding in the skin and mucous membranes.&nbsp;Sensitivity to sunlight.<\/li><li>Impaired glucose tolerance, which manifests itself as elevated blood sugar levels.&nbsp;Risk of developing&nbsp;diabetes&nbsp;.<\/li><li>Deafness (sometimes persistent).<\/li><\/ul>\n\n\n\n<p><em>Rare (less than 1 in 1000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting.<\/li><li>Diarrhea.<\/li><li>Inflammation\u00a0of blood vessels.\u00a0The symptoms depend on where the vessel \/ vessels are located.<\/li><li>Kidney inflammation, which can cause symptoms in the form of fever and pain.<\/li><li>Earwax.<\/li><li><span style=\"background-color: rgb(255, 255, 255); color: rgb(30, 30, 30);\">Abnormal sensations, such as ant crawling, tingling and a &#8220;sugar drinking feeling&#8221;.<\/span><\/li><li>Low number of\u00a0white blood cells\u00a0, which increases the risk of\u00a0infection\u00a0.<\/li><li>Fever.<\/li><\/ul>\n\n\n\n<p><em>Very rare (less than 1 in 10,000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute&nbsp;inflammation&nbsp;of the pancreas, which can be experienced as pain to varying degrees in the upper abdomen or between the shoulder blades, vomiting and fever.<\/li><li>High liver enzyme values \u200b\u200bdetected using blood tests.<\/li><li>Bile duct obstruction, which can cause symptoms such as pain, nausea and vomiting.<\/li><li>Impact on the blood picture and&nbsp;anemia&nbsp;.<\/li><\/ul>\n\n\n\n<p><em>No known frequency (can not be calculated from the available data):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High&nbsp;pH&nbsp;in the blood, which can cause very serious conditions such as lack of oxygen in the blood.<\/li><li>Lack of&nbsp;calcium&nbsp;or&nbsp;magnesium&nbsp;, which is detected by blood tests.&nbsp;May increase the risk of osteoporosis.<\/li><li>Increased level of&nbsp;urea&nbsp;in the blood, which is detected with the help of blood tests.<\/li><li>Blood clot.<\/li><li>Increased levels of&nbsp;sodium&nbsp;and chloride in the urine, which is detected with the help of blood tests.<\/li><li>Difficulty urinating.<\/li><li>Impaired renal function.<\/li><li>Skin and mucous membrane changes (sometimes severe).<\/li><li>Severe widespread skin damage (skin detachment).<\/li><li>Lichenoid reactions, characterized by small, itchy, reddish-purple, angular rashes on the skin, genitals or in the mouth.<\/li><li>Pseudo-Bartter syndrome (unusual genetic kidney disease).<\/li><li>Deterioration or activation of systemic lupus erythematosus (disease in which the body&#8217;s immune system attacks the body).<\/li><li>Acute&nbsp;generalized exanthematous&nbsp;pustulosis&nbsp;(AGEP) (sudden drug rash with fever).<\/li><li>Headache, dizziness, fainting and unconsciousness (caused by low&nbsp;blood pressure&nbsp;or other causes).<\/li><li>Muscle rupture (&nbsp;rhabdomyolysis&nbsp;) is often associated with very low potassium levels in the blood (severe&nbsp;hypokalaemia&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Lasix Retard<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.\u00a0Do not use this medicine after the expiry date which is stated on the carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is\u00a0furosemide.\u00a0One capsule contains 30 mg or 60 mg of\u00a0furosemide.<\/p>\n\n\n\n<p>The other ingredients are sucrose, corn starch, povidone, talc, shellac, stearic acid, alumina hydrate, gelatin, and dyes (yellow iron oxide E172, indigo carmine E132, titanium dioxide E171).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Appearance: hard capsules, green\/yellow.<\/p>\n\n\n\n<p><em>Depot capsule&nbsp;30 mg:<\/em><\/p>\n\n\n\n<p>Blister 30 pcs, 100&#215;1 (single-dose packaging)<\/p>\n\n\n\n<p>Plastic pipes 100 pcs<\/p>\n\n\n\n<p>Plastic jar 500 pcs (only for dose dispensing).<\/p>\n\n\n\n<p><em>Depot capsule&nbsp;60 mg:<\/em><\/p>\n\n\n\n<p>Blister 100&#215;1 (single dose pack)<\/p>\n\n\n\n<p>Plastic pipe 100 (2&#215;50) pcs<\/p>\n\n\n\n<p>Plastic jar 500 pcs (only for dose dispensing).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Sanofi Winthrop Industry<\/p>\n\n\n\n<p>1, rue de la Vierge<\/p>\n\n\n\n<p>Amber\u00e8s<\/p>\n\n\n\n<p>33565&nbsp;Carbon&nbsp;-Blanc C\u00e9dex<\/p>\n\n\n\n<p>France<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lasix Retard is a diuretic , a diuretic, which is used for fluid retention in the body&#8217;s tissues ( edema ) and for high blood pressure . Lasix Retard inhibits the kidneys&#8217; ability to reabsorb water and salt, leading to increased urinary excretion. Thus, the edema decreases or disappears .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15579],"tags":[12934,15488,2375,15483,2401,15484,15487,12932,12931,15485,15486],"class_list":["post-16198","post","type-post","status-publish","format-standard","hentry","category-medicines","category-l","tag-benefits-of-furosemide","tag-benefits-of-lasix-retard","tag-furosemide","tag-furosemide-capsule","tag-furosemide-side-effects","tag-lasix-retard","tag-lasix-retard-side-effects","tag-what-furosemide-is-used-for","tag-what-is-furosemide","tag-what-is-lasix-retard","tag-what-lasix-retard-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16198","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=16198"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16198\/revisions"}],"predecessor-version":[{"id":16296,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/16198\/revisions\/16296"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=16198"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=16198"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=16198"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}