{"id":15906,"date":"2021-11-24T07:06:51","date_gmt":"2021-11-24T07:06:51","guid":{"rendered":"https:\/\/zeepedia.com\/?p=15906"},"modified":"2021-11-25T11:46:53","modified_gmt":"2021-11-25T11:46:53","slug":"konakion-novum","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/konakion-novum\/","title":{"rendered":"Konakion Novum &#8211; Phytomenadione uses, dose and side effects"},"content":{"rendered":"\n<p>10 mg \/ ml&nbsp;injection&nbsp;solution<br>phytomenadione<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Konakion Novum is and what it is used for<\/h2>\n\n\n\n<p>Konakion Novum contains&nbsp;vitamin&nbsp;K&nbsp;<sub>1<\/sub>&nbsp;(phytomenadione), which is necessary for the blood to coagulate (coagulate).<\/p>\n\n\n\n<p>Konakion Novum is used for bleeding and the risk of bleeding due to vitamin K deficiency.<\/p>\n\n\n\n<p>Konakion Novum is also given as a preventive treatment to newborns.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Konakion Novum<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Konakion Novum<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to phytomenadione or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Konakion Novum.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you suffer from an increased risk of blood clots, e.g.&nbsp;due to heart valve prosthesis.<\/li><li>If you have impaired liver function.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Konakion Novum<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Konakion Novum counteracts the effects of&nbsp;warfarin&nbsp;and other anti-&nbsp;vitamin&nbsp;K drugs (drugs that inhibit the blood&#8217;s ability to clot).<\/p>\n\n\n\n<p>Antiepileptic&nbsp;drugs&nbsp;can affect the effect of&nbsp;vitamin&nbsp;K.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy:<\/em><\/p>\n\n\n\n<p>No known risks when used during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding:<\/em><\/p>\n\n\n\n<p>Konakion Novum passes into breast milk but is unlikely to affect breastfed infants.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No effect on the ability to drive and use machines has been observed.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Konakion Novum contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per\u00a0ampoule, ie essentially &#8216;sodium-free.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Konakion Novum<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong><em>In case of bleeding or risk of bleeding due to vitamin K deficiency:<\/em><\/strong><\/p>\n\n\n\n<p>Your doctor will decide which\u00a0dose\u00a0is right for you and how the medicine should be given to you.\u00a0Konakion Novum is given either\u00a0intravenously\u00a0(\u00a0injection\u00a0into a vein) or orally (orally).\u00a0For\u00a0injection, Konakion Novum must not be mixed with any other injection.\u00a0Konakion Novum can be diluted with glucose solution 50 mg\/ml (1: 5 or 1:10) but not sodium chloride solution.<\/p>\n\n\n\n<p><em>How to take Konakion Novum orally (by mouth):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Withdraw the desired amount of liquid from an&nbsp;ampoule&nbsp;using a&nbsp;syringe&nbsp;.<\/li><li>Remove the needle from the syringe and&nbsp;inject the&nbsp;contents directly into your mouth.<\/li><li>Rinse with liquid.<\/li><\/ul>\n\n\n\n<p><strong><em>Preventive treatment for newborns:<\/em><\/strong><\/p>\n\n\n\n<p>Konakion Novum can be given to your child as an\u00a0injection\u00a0into a vein,\u00a0injection\u00a0into a muscle, or through the mouth.\u00a0How it is given depends on what the medicine is used for and if your baby was born prematurely.<\/p>\n\n\n\n<p>Preventive treatment for bleeding due to vitamin K deficiency<\/p>\n\n\n\n<p><em>Healthy children who were born full or almost full<\/em><\/p>\n\n\n\n<p>These children may either:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>One&nbsp;injection&nbsp;(1 mg) at birth or shortly after, or<\/li><li>By mouth (orally) a first&nbsp;dose&nbsp;(2 mg) at birth or shortly after birth.&nbsp;This is followed by a second&nbsp;dose&nbsp;of 2 mg after 4-7 days and a third&nbsp;dose&nbsp;of 2 mg at 1 month of age.&nbsp;In children who only receive infant formula, the third&nbsp;dose&nbsp;may be&nbsp;excluded.<\/li><\/ul>\n\n\n\n<p><em>Premature babies or full-term babies with a special risk of bleeding<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>These babies will receive Konakion Novum as an&nbsp;injection&nbsp;at birth or shortly after birth.<\/li><li>More&nbsp;injections&nbsp;may be given later if there is still a risk of bleeding in your baby.<\/li><\/ul>\n\n\n\n<p>Additional dosage:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Children who receive&nbsp;vitamin&nbsp;K through the mouth and who are breastfed (who do not receive infant formula) may need several&nbsp;doses&nbsp;of&nbsp;vitamin&nbsp;K through the mouth.<\/li><li>Children who are fed a bottle of infant formula and who have received two&nbsp;doses&nbsp;of&nbsp;vitamin&nbsp;K by mouth may not need additional&nbsp;doses&nbsp;of&nbsp;vitamin&nbsp;K. This is because it is included in the infant formula.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Konakion Novum than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center (tel. 112) for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Konakion Novum<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Very rare (affects less than 1 user in 10,000):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity reaction&nbsp;with fever, rash, swelling and sometimes drop in blood pressure associated with&nbsp;intravenous&nbsp;injection&nbsp;.<\/li><li>Local reactions at the injection site.<\/li><\/ul>\n\n\n\n<p>If you get\u00a0any side effects, talk to your doctor or pharmacist.\u00a0This also applies to any\u00a0side effects\u00a0not mentioned in this information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Konakion Novum<\/h2>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Do not freeze.&nbsp;Store&nbsp;ampoule&nbsp;one in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and label after EXP:\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not use this medicine if the liquid in the&nbsp;ampoule&nbsp;is cloudy or has stratified.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is phytomenadione 10 mg per ml.<\/li><li>The other ingredients are glycocholic acid, sodium hydroxide, lecithin,&nbsp;hydrochloric acid&nbsp;, water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Clear or yellowish solution.<\/p>\n\n\n\n<p>Pack sizes: 5 x 1 ml.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>CHEPLAPHARM Arzneimittel GmbH<\/p>\n\n\n\n<p>Ziegelhof 24<\/p>\n\n\n\n<p>17489 Greifswald<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>CHEPLAPHARM Arzneimittel GmbH<\/p>\n\n\n\n<p>Ziegelhof 23-24<\/p>\n\n\n\n<p>17489 Greifswald<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Information is provided by<\/strong><\/p>\n\n\n\n<p>ProPharma Group Sweden AB<\/p>\n\n\n\n<p>Fleminggatan 18<\/p>\n\n\n\n<p>112 26 Stockholm<\/p>\n\n\n\n<p>Sweden<\/p>\n\n\n\n<p>email: pharmacovigilanceSE@propharmagroup.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Konakion Novum contains vitamin K 1 (phytomenadione), which is necessary for the blood to coagulate (coagulate).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12118],"tags":[15120,15115,15116,15119,15111,15114,15117,15112,15118,15113],"class_list":["post-15906","post","type-post","status-publish","format-standard","hentry","category-medicines","category-k","tag-benefits-of-konakion-novum","tag-benefits-of-phytomenadione","tag-konakion-novum","tag-konakion-novum-side-effects","tag-phytomenadione","tag-phytomenadione-side-effects","tag-what-is-konakion-novum","tag-what-is-phytomenadione","tag-what-konakion-novum-is-used-for","tag-what-phytomenadione-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/15906","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=15906"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/15906\/revisions"}],"predecessor-version":[{"id":15952,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/15906\/revisions\/15952"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=15906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=15906"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=15906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}