{"id":15670,"date":"2021-11-13T10:27:24","date_gmt":"2021-11-13T10:27:24","guid":{"rendered":"https:\/\/zeepedia.com\/?p=15670"},"modified":"2021-11-19T18:17:34","modified_gmt":"2021-11-19T18:17:34","slug":"jentadueto","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/jentadueto\/","title":{"rendered":"Jentadueto &#8211; Linagliptin \/ metformin hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 mg \/ 850 mg and 2.5 mg \/ 1,000 mg&nbsp;film-coated tablets<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/trajenta\/\">linagliptin<\/a> \/ metformin hydrochloride<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Jentadueto is and what it is used for<\/h2>\n\n\n\n<p>The name of your tablet is Jentadueto.&nbsp;It contains two different active substances, linagliptin and&nbsp;metformin.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Linagliptin belongs to a group of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors).<\/li><li>Metformin&nbsp;belongs to a group of medicines called biguanides.<\/li><\/ul>\n\n\n\n<p><strong>How Jentadueto works<\/strong><\/p>\n\n\n\n<p>The two active substances together help to regulate blood sugar levels in adult patients with a type of&nbsp;diabetes&nbsp;called &#8220;diabetes mellitus type 2&#8221;.&nbsp;Together with diet and exercise, this medicine helps to improve the level and effect of&nbsp;insulin&nbsp;after a meal and reduces the amount of sugar formed by your body.<\/p>\n\n\n\n<p>This medicine can be taken alone or in combination with certain other medicines for&nbsp;diabetes&nbsp;such as sulphonylureas, empagliflozin or&nbsp;insulin.<\/p>\n\n\n\n<p><strong>What is type 2&nbsp;diabetes?<\/strong><\/p>\n\n\n\n<p>Type 2&nbsp;diabetes&nbsp;is a condition that means that your body does not produce enough&nbsp;insulin&nbsp;and that the&nbsp;insulin&nbsp;that the body produces does not work as well as it should.&nbsp;Your body can also produce too much sugar.&nbsp;When this happens, sugar (&nbsp;glucose&nbsp;)&nbsp;accumulates&nbsp;in the blood.&nbsp;It can lead to serious medical problems such as heart disease, kidney disease, blindness and amputation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Jentadueto<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Jentadueto:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to linagliptin or&nbsp;metformin&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have severe renal impairment.<\/li><li>if you have uncontrolled&nbsp;diabetes&nbsp;with, for example, severe&nbsp;hyperglycaemia&nbsp;(high blood sugar), nausea, vomiting, diarrhea, rapid weight loss,&nbsp;lactic acidosis&nbsp;(see &#8220;Risk of lactic acidosis&#8221; below) or&nbsp;ketoacidosis&nbsp;.&nbsp;Ketoacidosis&nbsp;is a condition in which substances called&nbsp;ketone bodies&nbsp;accumulate in the blood, which can lead to diabetic precoma.&nbsp;Symptoms include stomach pain, rapid and deep breathing, drowsiness or that your breath has a different, fruity odor.<\/li><li>if you have ever had diabetes coma (&nbsp;ketoacidosis&nbsp;).<\/li><li>if you have a severe&nbsp;infection&nbsp;such as an&nbsp;infection&nbsp;of the lungs or&nbsp;bronchi&nbsp;or kidneys.&nbsp;Severe&nbsp;infections&nbsp;can cause kidney problems, which can put you at risk for lactic acidosis (see \u201cWarnings and Precautions\u201d).<\/li><li>if you have lost a lot of water (dehydration), e.g.&nbsp;due to prolonged or severe diarrhea, or if you have vomited several times in a row.&nbsp;Dehydration can cause kidney problems, which can put you at risk for lactic acidosis (see \u201cWarnings and Precautions\u201d).<\/li><li>if you are being treated for&nbsp;acute&nbsp;heart failure&nbsp;or have recently had a heart attack, have severe circulatory problems (such as&nbsp;shock&nbsp;), or have difficulty breathing.&nbsp;This can lead to a lack of oxygen supply to the&nbsp;tissues&nbsp;, and it can increase the risk of lactic acidosis (see section &#8220;Warnings and precautions&#8221;).<\/li><li>if you have liver problems.<\/li><li>if you drink too much alcohol either if you do it every day or only periodically (see the section \u201cGirl duo with alcohol\u201d).<\/li><\/ul>\n\n\n\n<p>Do not take Jentadueto if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to Jentadueto with your doctor, pharmacist or nurse:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have type 1&nbsp;diabetes&nbsp;(your body does not make&nbsp;insulin&nbsp;).&nbsp;Jentadueto should not be used in the treatment of this condition.<\/li><li>If you are taking&nbsp;insulin&nbsp;or a&nbsp;diabetes&nbsp;medicine&nbsp;called &#8220;sulphonylurea&#8221;, your doctor may want to reduce your&nbsp;dose of&nbsp;insulin&nbsp;or sulphonylurea when you take one of them with Jentadueto to avoid low blood sugar (&nbsp;hypoglycaemia&nbsp;).<\/li><li>if you have or have had a disease of the pancreas.<\/li><\/ul>\n\n\n\n<p>Contact your doctor if you have symptoms of&nbsp;acute&nbsp;pancreatitides, such as severe and persistent abdominal pain.<\/p>\n\n\n\n<p>If you get blisters on your skin, it could be a sign of a condition called bullous&nbsp;pemphigoid.&nbsp;Your doctor may tell you to stop taking Jentadueto.<\/p>\n\n\n\n<p>If you are not sure if any of the above applies to you, talk to your doctor, pharmacist or nurse before taking Jentadueto.<\/p>\n\n\n\n<p>Diabetic skin problems are a common complication of&nbsp;diabetes.&nbsp;You should follow the recommendations for skin and foot care from your doctor or nurse.<\/p>\n\n\n\n<p><strong>Risk of&nbsp;lactic acidosis<\/strong><\/p>\n\n\n\n<p>Because metformin content can Jentadueto cause the very rare, but very serious&nbsp;side effect&nbsp;a&nbsp;lactic acidosis, particularly if your kidneys are not working properly.&nbsp;The risk of developing&nbsp;lactic acidosis&nbsp;is also increased in uncontrolled&nbsp;diabetes, severe&nbsp;infections, prolonged fasting or alcohol intake, dehydration (see more information below), liver problems and conditions where part of the body has reduced oxygen supply (including&nbsp;acute&nbsp;severe heart disease).<\/p>\n\n\n\n<p>If any of the above apply to you, talk to your doctor for further information.<\/p>\n\n\n\n<p><strong>Stop taking Jentadueto for a short time if you have a condition that may be associated with dehydration,<\/strong>&nbsp;such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal.&nbsp;Talk to a doctor for further instructions.<\/p>\n\n\n\n<p><strong>Stop taking Jentadueto and contact a doctor or nearest hospital immediately if you get any of the symptoms of&nbsp;lactic acidosis<\/strong>&nbsp;as the condition may lead to&nbsp;coma.<\/p>\n\n\n\n<p>The symptoms of&nbsp;lactic acidosis&nbsp;include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting<\/li><li>abdominal pain (stomach pain)<\/li><li>muscle cramps<\/li><li>a general feeling of not feeling well and pronounced fatigue<\/li><li>hard to breathe<\/li><li>lowered body temperature and&nbsp;heart rate<\/li><\/ul>\n\n\n\n<p>Lactic acidosis&nbsp;is an&nbsp;acute&nbsp;medical condition that must be treated in a hospital.<\/p>\n\n\n\n<p>If you are going to undergo a major operation, you must stop taking Jentadueto during the operation and a certain time after it.&nbsp;Your doctor will decide when you need to stop taking Jentadueto and when you should start taking it again.<\/p>\n\n\n\n<p>During treatment with Jentadueto, your doctor will check your kidney function at least once a year or more often if you are older and\/or if your kidney function is deteriorating.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>This medicine is not recommended for children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Jentadueto<\/h2>\n\n\n\n<p>If you need to get an&nbsp;injection&nbsp;in the blood with contrast media that contain iodine, for example in connection with X-rays or&nbsp;computed tomography, you must stop taking Jentadueto before or at the time of&nbsp;injection.&nbsp;Your doctor will decide when you need to stop taking Jentadueto and when you should start taking it again.<\/p>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken or might take any other medicines.&nbsp;You may need to do more blood sugar and kidney function tests, or&nbsp;your&nbsp;doctor may need to adjust the&nbsp;dose&nbsp;of Jentadueto.&nbsp;You must mention the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs that increase urine production (&nbsp;diuretics&nbsp;)<\/li><li>drugs used to treat pain and&nbsp;inflammation&nbsp;(&nbsp;NSAIDs&nbsp;and COX 2 inhibitors, such as&nbsp;ibuprofen&nbsp;and celecoxib)<\/li><li>certain medicines for the treatment of high&nbsp;blood pressure&nbsp;(&nbsp;ACE inhibitors&nbsp;and&nbsp;angiotensin&nbsp;II receptor antagonists).<\/li><li>medicines that may alter the amount of&nbsp;metformin&nbsp;in your blood, especially if you have impaired kidney function (eg verapamil, rifampicin, cimetidine, <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tivicay\/\">dolutegravir<\/a>, ranolazine, trimethoprim, vandetanib, isavuconazole, crizotinib, olaparib).<\/li><li>carbamazepine, phenobarbital or&nbsp;phenytoin&nbsp;.&nbsp;These are medications used for seizures or&nbsp;chronic&nbsp;pain.<\/li><li>rifampicin.&nbsp;It is an&nbsp;antibiotic&nbsp;used to treat&nbsp;infections&nbsp;such as&nbsp;tuberculosis&nbsp;.<\/li><li>drugs used in the treatment of diseases with&nbsp;inflammation&nbsp;such as&nbsp;asthma&nbsp;and&nbsp;arthritis&nbsp;(&nbsp;corticosteroids&nbsp;).<\/li><li>bronchodilators&nbsp;(\u03b2\u2011&nbsp;sympathomimetics&nbsp;) used in the treatment of&nbsp;asthma&nbsp;.<\/li><li>medicines containing alcohol.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Girl duo with alcohol<\/h2>\n\n\n\n<p>Avoid high alcohol intake while taking Jentadueto as alcohol may increase the risk of&nbsp;lactic acidosis&nbsp;(see section &#8220;Warnings and precautions&#8221;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>You should not use Jentadueto during pregnancy.&nbsp;It is not known if this medicine is harmful to the unborn baby.<\/p>\n\n\n\n<p>Metformin is&nbsp;excreted in small amounts in breast milk.&nbsp;It is not known whether linagliptin is excreted in human milk.&nbsp;Talk to your doctor if you want to breastfeed while taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Jentadueto has no or negligible effect on the ability to drive and use machines.&nbsp;However, the use of Jentadueto with medicines called sulphonylureas or with&nbsp;insulin&nbsp;may cause low blood sugar (&nbsp;hypoglycaemia&nbsp;), which may affect your ability to drive and use machines and work without a secure foothold.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Jentadueto<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The amount of Jentadueto you should take varies depending on your condition and the&nbsp;dose&nbsp;you are currently taking&nbsp;metformin&nbsp;and\/or separate tablets of linagliptin and&nbsp;metformin.&nbsp;Your doctor will tell you exactly what&nbsp;dose&nbsp;of this medicine to take.<\/p>\n\n\n\n<p><strong>How to take this medicine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>take one tablet twice a day by mouth according to the&nbsp;dose&nbsp;prescribed by your doctor.<\/li><li>in connection with a meal to reduce the risk of stomach upset.<\/li><\/ul>\n\n\n\n<p>You should not exceed the maximum recommended daily&nbsp;dose&nbsp;of 5 mg linagliptin and 2,000 mg metformin hydrochloride.<\/p>\n\n\n\n<p>Continue to take Jentadueto for as long as your doctor prescribes it so that you can continue to control your blood sugar.&nbsp;Your doctor may prescribe this medicine together with another oral diabetes medicine or&nbsp;insulin.&nbsp;Remember to use all medications as directed by your doctor to achieve the best results for your health.<\/p>\n\n\n\n<p>You should continue with your diet during treatment with Jentadueto and ensure that your carbohydrate intake is evenly distributed throughout the day.&nbsp;If you are overweight, continue your calorie-restricted diet according to the instructions.&nbsp;This medicine alone is unlikely to cause abnormally low blood sugar (&nbsp;hypoglycaemia&nbsp;).&nbsp;However, when Jentadueto is used with a sulphonylurea or with&nbsp;insulin, low blood sugar may occur and your doctor may reduce the&nbsp;dose of&nbsp;one of your sulphonylurea or&nbsp;insulin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Jentadueto than you should<\/h2>\n\n\n\n<p>If you take more Jentadueto tablets than you should, you may get lactic acidosis.&nbsp;The symptoms of lactic acidosis are non-specific such as malaise or nausea, vomiting, stomach pain with muscle cramps, general malaise with severe fatigue, and difficulty breathing.&nbsp;Additional symptoms are decreased body temperature and heart rate.&nbsp;<strong>If you get such symptoms, you may need immediate hospitalization, as lactic acidosis can lead to&nbsp;coma.&nbsp;Stop taking this medicine immediately and contact your doctor or nearest hospital immediately (see section 2).&nbsp;Take the medicine pack with you.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Jentadueto<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose, take it as soon as you remember.&nbsp;If it is soon time for&nbsp;your&nbsp;next&nbsp;dose, skip the missed&nbsp;dose.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Never take two&nbsp;doses&nbsp;at the same time (morning or evening).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Jentadueto<\/h2>\n\n\n\n<p>Keep taking Jentadueto until your doctor tells you to stop.&nbsp;This is to keep control of your blood sugar.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Some symptoms require immediate medical attention<\/strong><\/p>\n\n\n\n<p>You should stop using Jentadueto and see a doctor immediately if you experience the following symptoms of low blood sugar (&nbsp;hypoglycaemia&nbsp;): tremors, sweating, anxiety, blurred vision, tingling in the lips, paleness, mood swings or confusion.&nbsp;Hypoglycaemia&nbsp;(frequency: very common (may affect more than 1 user in 10)) is an identified&nbsp;side effect&nbsp;of the combination of Jentadueto and sulphonylurea and the combination of Jentadueto and&nbsp;insulin.<\/p>\n\n\n\n<p>Jentadueto can cause the very rare (may affect up to 1 user in 10,000), but very serious&nbsp;side effects&nbsp;a&nbsp;lactic acidosis&nbsp;(see section &#8220;Warnings and precautions&#8221;).&nbsp;If this happens to you, you must&nbsp;stop taking Jentadueto and contact a doctor or nearest hospital immediately&nbsp;as&nbsp;lactic acidosis&nbsp;may lead to&nbsp;coma.<\/p>\n\n\n\n<p>Some patients have developed&nbsp;inflammation&nbsp;of the pancreas (&nbsp;pancreatitis, rare, may occur in up to 1 in 1,000 users).<\/p>\n\n\n\n<p>STOP taking Jentadueto and contact a doctor immediately if you notice any of the following serious side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe and persistent pain in the abdomen (stomach) that may radiate to the back, as well as nausea and vomiting, as this may be a sign of&nbsp;inflammation&nbsp;of the pancreas (&nbsp;pancreatitis&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;of Jentadueto include:<\/strong><\/p>\n\n\n\n<p>Some patients have experienced allergic reactions (frequency: rare) which may be severe, including wheezing and shortness of breath (bronchial hyperreactivity, frequency: uncommon (may affect up to 1 in 100 people)).&nbsp;Some patients have experienced skin rash (frequency: uncommon), hives (&nbsp;urticaria, frequency: rare) and swelling of the face, lips, tongue and throat which may cause difficulty breathing or swallowing (&nbsp;angioedema, frequency: rare).&nbsp;If you get any of the symptoms listed above, stop taking Jentadueto and contact your doctor immediately.&nbsp;Your doctor may&nbsp;prescribe&nbsp;a medicine to treat your allergic reaction and another medicine for your&nbsp;diabetes.<\/p>\n\n\n\n<p>Some patients experienced the following&nbsp;side effects&nbsp;while using Jentadueto:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Common (may affect up to 1 in 10 people): diarrhea, increase in&nbsp;enzyme&nbsp;and&nbsp;lipase&nbsp;in the blood, nausea<\/li><li>Uncommon:&nbsp;inflammation&nbsp;of the nose or throat (&nbsp;nasopharyngitis&nbsp;), cough, loss of appetite (decreased appetite), vomiting, increase of an&nbsp;enzyme&nbsp;in the blood (amylase),&nbsp;itching&nbsp;(&nbsp;pruritus&nbsp;)<\/li><li>Rare: blistering of the skin (bullous&nbsp;pemphigoid&nbsp;)<\/li><\/ul>\n\n\n\n<p>Some patients experienced the following&nbsp;side effects&nbsp;when using Jentadueto with&nbsp;insulin<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Uncommon: disorders of the liver function, constipation.<\/li><\/ul>\n\n\n\n<p><strong>Side effects&nbsp;are when using&nbsp;metformin&nbsp;alone, not described for Jentadueto<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Very common: stomach pain.<\/li><li>Common (may affect up to 1 in 10 people): a metallic taste in the mouth (taste changes).<\/li><li>Very rare (may affect up to 1 in 10,000 people): decreased\u00a0vitamin\u00a0B12 <\/li><li>levels,\u00a0hepatitis\u00a0(liver disease), skin reactions such as redness of the skin (\u00a0erythema\u00a0).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Jentadueto<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister, jar and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special temperature instructions.<\/p>\n\n\n\n<p><em>Blister:<\/em>&nbsp;Store in the original package.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p><em>Jar:<\/em>&nbsp;Close the jar tightly.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Do not use this medicine if the package is damaged or shows signs of tampering.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are linagliptin and metformin hydrochloride.<\/li><li>Each Jentadueto 2.5 mg \/ 850 mg film-coated tablet contains 2.5 mg linagliptin and 850 mg metformin hydrochloride.<\/li><li>Each Jentadueto 2.5 mg \/ 1,000 mg film-coated tablet contains 2.5 mg linagliptin and 1,000 mg metformin hydrochloride.<\/li><li>Other ingredients are:<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Tablet core:&nbsp;arginine&nbsp;, copovidone, magnesium stearate, corn starch,&nbsp;colloidal&nbsp;anhydrous silica.<\/li><li>Film coating: hypromellose, titanium dioxide (E171), talc, propylene glycol.Jentadueto 2.5 mg \/ 850 mg film-coated tablets also contain red iron oxide (E172) and yellow iron oxide (E172).Jentadueto 2.5 mg \/ 1,000 mg film-coated tablets also contain red iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Jentadueto 2.5 mg \/ 850 mg are oval, biconvex, light orange, film-coated tablets (tablets).&nbsp;They are embossed with &#8220;D2 \/ 850&#8221; on one side and embossed with the Boehringer Ingelheim logo on the other.<\/p>\n\n\n\n<p>Jentadueto 2.5 mg \/ 1,000 mg are oval, biconvex, light pink, film-coated tablets (tablets).&nbsp;They are embossed with &#8220;D2 \/ 1000&#8221; on one side and embossed with the Boehringer Ingelheim logo on the other.<\/p>\n\n\n\n<p>Jentadueto is available in perforated single-dose blisters with 10 x 1, 14 x 1, 28 x 1, 30 x 1, 56 x 1, 60 x 1, 84 x 1, 90 x 1, 98 x 1, 100 x 1 and 120 x 1 film-coated tablets and multipacks containing 120 x 1 (2 cartons of 60 x 1), 180 x 1 (2 cartons of 90 x 1), 180 x 1 (3 cartons of 60 x 1) and 200 x 1 (2 cartons of 100 x 1) ) film-coated tablets.<\/p>\n\n\n\n<p>Jentadueto is also available in plastic jars with plastic screw caps and a silica gel as a desiccant.&nbsp;The jars contain 14, 60 or 180 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Boehringer Ingelheim International GmbH<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Boehringer Ingelheim Pharma GmbH &amp; Co.&nbsp;KG<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Boehringer Ingelheim Ellas AE<\/p>\n\n\n\n<p>5th km Paiania &#8211; Markopoulo<\/p>\n\n\n\n<p>Koropi Attiki, 194 00<\/p>\n\n\n\n<p>Greece<\/p>\n\n\n\n<p>Dragenopharm Apotheker P\u00fcschl GmbH<\/p>\n\n\n\n<p>G\u00f6llstra\u00dfe 1<\/p>\n\n\n\n<p>84529 Tittmoning<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>SCS Boehringer Ingelheim Comm.VTel: +32 2 773 33 11<\/td><td><strong>Lithuania<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGLithuanian branchesTel: +370 5 2595942<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Boringer Inglerheim Rivgambi and Co.&nbsp;KG -clone of BulgariaTel: +359 2 958 79 98<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>SCS Boehringer Ingelheim Comm.VTel: +32 2 773 33 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Boehringer Ingelheim spol.&nbsp;s roTel: +420 234 655 111<\/td><td><strong>Hungary<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGMagyarorsz\u00e1gi Fi\u00f3ktelepeTel: +36 1 299 8900<\/td><\/tr><tr><td><strong>Denmark<\/strong>Boehringer Ingelheim Danmark A \/ STel: +45 39 15 88 88<\/td><td><strong>Malta<\/strong>Boehringer Ingelheim Ireland Ltd.Tel: +353 1 295 9620<\/td><\/tr><tr><td><strong>Germany<\/strong>Boehringer Ingelheim Pharma GmbH &amp; Co.&nbsp;KGTel: +49 (0) 800 77 90 900<\/td><td><strong>The Netherlands<\/strong>Boehringer Ingelheim bvTel: +31 (0) 800 22 55 889<\/td><\/tr><tr><td><strong>Eesti<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGEesti subsidiaryTel: +372 612 8000<\/td><td><strong>Norway<\/strong>Boehringer Ingelheim Norway KSTel: +47 66 76 13 00<\/td><\/tr><tr><td><strong>Greece<\/strong>Boehringer Ingelheim Ellas AET\u03b7\u03bb: +30 2 10 89 06 300<\/td><td><strong>Austria<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGTel: +43 1 80 105-7870<\/td><\/tr><tr><td><strong>Spain<\/strong>Boehringer Ingelheim Espa\u00f1a, SATel: +34 93 404 51 00<\/td><td><strong>Poland<\/strong>Boehringer Ingelheim Sp.&nbsp;z ooTel: +48 22 699 0 699<\/td><\/tr><tr><td><strong>France<\/strong>Boehringer Ingelheim France SASTel: +33 3 26 50 45 33<\/td><td><strong>Portugal<\/strong>Boehringer Ingelheim Portugal, Lda.Tel: +351 21 313 53 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>Boehringer Ingelheim Zagreb dooTel: +385 1 2444 600<\/td><td><strong>Romania<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGVienna &#8211; Sucursala BucharestTel: +40 21 302 2800<\/td><\/tr><tr><td><strong>Ireland<\/strong>Boehringer Ingelheim Ireland Ltd.Tel: +353 1 295 9620<\/td><td><strong>Slovenia<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG,Podru\u017enica LjubljanaTel: +386 1 586 40 00<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td><td><strong>Slovak Republic<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG,organizing serviceTel: +421 2 5810 1211<\/td><\/tr><tr><td><strong>Italy<\/strong>Boehringer Ingelheim Italia SpATel: +39 02 5355 1<\/td><td><strong>Finland \/ Finland<\/strong>Boehringer Ingelheim Finland KyPuh \/ Tel: +358 10 3102 800<\/td><\/tr><tr><td><strong>.\u03a0\u03c1\u03bf\u03c2<\/strong>Boehringer Ingelheim Ellas AET\u03b7\u03bb: +30 2 10 89 06 300<\/td><td><strong>Sweden<\/strong>Boehringer Ingelheim ABTel: +46 8 721 21 00<\/td><\/tr><tr><td><strong>Latvia<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGLatvian branchTel: +371 67 240 011<\/td><td><strong>United Kingdom&nbsp;<\/strong>&nbsp;<strong>(Northern Ireland)<\/strong>Boehringer Ingelheim Ireland Ltd.Tel: +353 1 295 9620<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The name of your tablet is Jentadueto. It contains two different active substances, linagliptin and metformin .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12117],"tags":[14901,14129,14317,14896,14900,14899,14125,14902,14128,3466,3469,4837,14897,14126,4836,14898,14127,14316],"class_list":["post-15670","post","type-post","status-publish","format-standard","hentry","category-medicines","category-j","tag-benefits-of-jentadueto","tag-benefits-of-linagliptin","tag-benefits-of-metformin-hydrochloride","tag-jentadueto","tag-jentadueto-side-effects","tag-jentadueto-tablet","tag-linagliptin","tag-linagliptin-side-effects-2","tag-linagliptin-tablet","tag-metformin-hydrochloride","tag-metformin-hydrochloride-side-effects","tag-metformin-hydrochloride-tablet","tag-what-is-jentadueto","tag-what-is-linagliptin","tag-what-is-metformin-hydrochloride","tag-what-jentadueto-is-used-for","tag-what-linagliptin-is-used-for","tag-what-metformin-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/15670","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=15670"}],"version-history":[{"count":7,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/15670\/revisions"}],"predecessor-version":[{"id":15810,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/15670\/revisions\/15810"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=15670"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=15670"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=15670"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}