{"id":14581,"date":"2021-10-06T06:46:19","date_gmt":"2021-10-06T06:46:19","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14581"},"modified":"2021-10-09T16:22:21","modified_gmt":"2021-10-09T16:22:21","slug":"isosorbide-mononitrate-astimex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/isosorbide-mononitrate-astimex\/","title":{"rendered":"Isosorbide mononitrate Astimex &#8211; Isosorbide mononitrate uses, dose and side effects"},"content":{"rendered":"\n<p>60 mg&nbsp;prolonged-release tablet&nbsp;is<br>isosorbide mononitrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Is Astosex Isosorbide Mononitrate is and what it is used for<\/h2>\n\n\n\n<p>Isosorbide mononitrate Astimex 60 mg&nbsp;prolonged-release tablets&nbsp;(hereinafter referred to&nbsp;as&nbsp;Isosorbide&nbsp;mononitrate&nbsp;Astimex in this leaflet) contain the active substance&nbsp;isosorbide mononitrate.&nbsp;It belongs to the group of medicines called nitrates.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>It is used to prevent chest pain \/ angina (angina).&nbsp;Anxiety is an oppressive pain or a feeling of pressure over the chest, but the pain can also be felt in the neck or arm.&nbsp;The pain occurs when the heart muscle does not get enough oxygen to be able to pump around the blood.<\/li><li>It works by causing the blood vessels to relax and dilate.&nbsp;This makes it easier for the heart to pump around the blood in the body, which improves the flow of blood and oxygen to the heart muscle.<\/li><\/ul>\n\n\n\n<p>The tablets are made so that the drug is released slowly over several hours.<\/p>\n\n\n\n<p>Isosorbide mononitrate contained in&nbsp;Isosorbide mononitrate&nbsp;Astimex may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Astosex Isosorbide Mononitrate<\/h2>\n\n\n\n<p>DO NOT use these tablets to treat sudden chest pain (acute angina).&nbsp;Instead, seek medical attention immediately.&nbsp;These tablets act too slowly to treat this and are used only to prevent angina symptoms.<\/p>\n\n\n\n<p><strong>Do not use Isosorbide Mononitrate Astimex:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to isosorbide mononitrate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have ever had a&nbsp;stroke&nbsp;.<\/li><li>if you have very low blood pressure.<\/li><li>if you have severe anemia.<\/li><li>if you have heart problems called &#8220;cardiomyopathy&#8221; or &#8220;pericarditis&#8221; or have narrow heart valves.<\/li><li>if you are taking sildenafil or a similar medicine called phosphodiesterase type 5 inhibitor (used in male impotence).&nbsp;See section \u201cOther medicines and Isosorbide mononitrate Astimex\u201d.<\/li><\/ul>\n\n\n\n<p>Isosorbide mononitrate should not be used in patients with&nbsp;acute&nbsp;myocardial infarction with low filling pressure, head injury, cerebral haemorrhage, severe hypotension, or low blood volume.<\/p>\n\n\n\n<p>Do not take Astosex Isosorbide Mononitrate if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Astimex Isosorbide Mononitrate:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have impaired thyroid function.<\/li><li>if you have hypoxemia (low oxygen content in the blood, eg due to a lung disease).<\/li><li>if you have hypothermia (symptoms are chills, unusual sleepiness, confusion).<\/li><li>if you are malnourished.<\/li><li>if you have severe liver or kidney disease.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Isosorbide mononitrate Astimex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This includes over-the-counter medicines and herbal medicines.&nbsp;This is because Astosex Isosorbide Mononitrate may affect the way other medicines work and other&nbsp;Astimex&nbsp;Isosorbide Mononitrate&nbsp;may affect.<\/p>\n\n\n\n<p>Do not take Isime sorbid mononitrate Astimex if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sildenafil or similar medicines called phosphodiesterase type 5 inhibitors (used in male impotence)<\/li><\/ul>\n\n\n\n<p>If you are taking any of these medicines for erectile dysfunction, concomitant use of nitrate medicines such as Isosorbide mononitrate Astimex may cause a severe and potentially dangerous drop in blood pressure.&nbsp;This can lead to fainting or, in the worst case, a heart attack.<\/p>\n\n\n\n<p>The following medicines may affect the effect of Astosex Isosorbide Mononitrate:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>norepinephrine (used to treat severe and severe hypotension)<\/li><li>acetylcholine (used to reduce&nbsp;pupil&nbsp;one during cataract surgery and other eye surgeries)<\/li><li>histamine (mainly used to diagnose certain diseases)<\/li><li>all blood pressure medications (eg beta blockers, calcium channel blockers,&nbsp;vasodilators&nbsp;, angiotensin II receptor antagonists, ACE inhibitors).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Isosorbide mononitrate Astimex with alcohol<\/h2>\n\n\n\n<p>Avoid drinking alcohol while taking Isosorbide mononitrate Astimex, as the&nbsp;side effect of&nbsp;low blood pressure may be worse than usual and you may feel dizzy or faint.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may have a headache or feel dizzy after taking&nbsp;Astosex&nbsp;Isosorbide Mononitrate.&nbsp;If so, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are always responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharp attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects.&nbsp;Descriptions of these effects and side effects can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Isosorbide mononitrate Astimex contains lactose and sucrose.<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Astimex Isosorbide Mononitrate<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>How to take the medicine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The tablets can be divided into two equal doses.<\/li><li>Take the tablets with half a glass of water.<\/li><li>Do not crush or chew the tablets.<\/li><\/ul>\n\n\n\n<p><strong>How much to take<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended dose is one or two Isosorbide Mononitrate Astimex 60 mg per day.<\/li><li>Take the medicine in the morning.<\/li><li>Your doctor may prescribe you a lower starting dose to avoid the&nbsp;side effects&nbsp;of treatment with Isosorbide mononitrate Astimex.&nbsp;Your&nbsp;dose&nbsp;can be from half a tablet (30 mg) up to two tablets (120 mg) per day.<\/li><\/ul>\n\n\n\n<p><strong>Do not take Astimex Isosorbide Mononitrate in case of a sudden angina attack.&nbsp;If you have a sudden attack, take a tablet of&nbsp;glyceryl trinitrate&nbsp;(follow the instructions on the label).<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children<\/h2>\n\n\n\n<p>Do not give these tablets to children.<\/p>\n\n\n\n<p><strong>Use for the elderly<\/strong><\/p>\n\n\n\n<p>If you are older, your dose should be the same as above, except if you have low blood pressure or severe liver or kidney disease &#8211; you should always follow your doctor&#8217;s instructions.<\/p>\n\n\n\n<p>If you are already taking medicines such as beta-blockers or calcium channel blockers, tell your doctor or pharmacist, as your doctor may need to adjust your dose of Isosorbide mononitrate Astimex or your other treatment (see section 2 \u201cWhat you need to know before taking Isosorbide mononitrate Astimex\u201d).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Isomezoride mononitrate Astimex than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.&nbsp;If you go to the hospital, bring the medicine pack so that the tablets can be identified.<\/p>\n\n\n\n<p>Symptoms of overdose may include:<\/p>\n\n\n\n<p>Throbbing headaches, agitation, cold sweats, nausea, vomiting, dizziness, fainting, and palpitations.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Isosorbide mononitrate Astimex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you miss a&nbsp;dose&nbsp;, take it as soon as you remember.&nbsp;But if it&#8217;s almost time for your next dose, skip the missed&nbsp;dose&nbsp;.<\/li><li>Do not take a double dose to make up for a forgotten tablet.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Isime sorbid mononitrate Astimex<\/h2>\n\n\n\n<p><strong>Do <\/strong>not <strong>suddenly&nbsp;stop&nbsp;taking&nbsp;Isosorbide Mononitrate&nbsp;Astimex tablets as this may make your angina worse.&nbsp;<\/strong>If your treatment is to be stopped, this should be done gradually.&nbsp;Be sure to follow your doctor&#8217;s instructions.&nbsp;If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Headaches can occur when treatment is started but usually disappear after 1-2 weeks of treatment.<\/p>\n\n\n\n<p>Low blood pressure with symptoms such as dizziness and nausea with dizziness in isolated cases has been reported occasionally.&nbsp;These symptoms usually disappear with continued treatment.<\/p>\n\n\n\n<p>Other possible side effects:<\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Low blood pressure.&nbsp;This can make you feel weak or dizzy.<\/li><li>Increased&nbsp;heart rate&nbsp;.<\/li><li>Headache<\/li><li>Dizziness<\/li><li>Nausea<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting<\/li><li>Diarrhea<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fainting<\/li><li>Rash<\/li><li>Itching<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle pain<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Isosorbide mononitrate Astimex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children<\/li><li>Do not store above 25 \u00b0 C<\/li><li>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is isosorbide mononitrate.&nbsp;Each tablet contains 60 mg of the active substance.<\/li><li>The other ingredients are hydroxypropyl methylcellulose 2208,&nbsp;lactose&nbsp;, sucrose, maltodextrin, magnesium stearate, silica&nbsp;colloidal&nbsp;anhydrous, iron oxide yellow (E \u2011 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Isosorbide mononitrate Astimex tablets are light yellow biconvex, oval, with a scoreline on both sides and marked &#8220;DX 31&#8221; on one side.<\/p>\n\n\n\n<p>Isosorbide mononitrate&nbsp;Astimex is available in blister packs containing 28, 30, or 98 tablets.&nbsp;Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Dexcel Pharma GmbH<\/p>\n\n\n\n<p>Carl-Zeiss-Stra\u00dfe 2<\/p>\n\n\n\n<p>63755 Alzenau,<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer&nbsp;<\/strong><strong>&nbsp;and agent:&nbsp;<\/strong><\/p>\n\n\n\n<p>Astimex pharma AB&nbsp;<\/p>\n\n\n\n<p>Isafjordsgatan 36<\/p>\n\n\n\n<p>164 40 Kista<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Isosorbide mononitrate Astimex 60 mg prolonged-release tablets (hereinafter referred to as Isosorbide mononitrate Astimex in this leaflet) contain the active substance isosorbide mononitrate. It belongs to the group of medicines called nitrates.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[12116,2200],"tags":[12209,12220,12223,12213,12219,12224,2210,12210,12221,12222,12211],"class_list":["post-14581","post","type-post","status-publish","format-standard","hentry","category-i","category-medicines","tag-isosorbide-mononitrate","tag-isosorbide-mononitrate-astimex","tag-isosorbide-mononitrate-astimex-tablet","tag-isosorbide-mononitrate-tablet","tag-side-effects-of-isosorbide-mononitrate","tag-side-effects-of-isosorbide-mononitrate-astimex","tag-tablet","tag-what-is-isosorbide-mononitrate","tag-what-is-isosorbide-mononitrate-astimex","tag-what-isosorbide-mononitrate-astimex-is-used-for","tag-what-isosorbide-mononitrate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14581"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14581\/revisions"}],"predecessor-version":[{"id":14734,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14581\/revisions\/14734"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}