{"id":14576,"date":"2021-10-06T06:44:09","date_gmt":"2021-10-06T06:44:09","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14576"},"modified":"2021-10-09T16:23:20","modified_gmt":"2021-10-09T16:23:20","slug":"isopto-atropine","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/isopto-atropine\/","title":{"rendered":"Isopto-Atropine &#8211; Atropine sulphate uses, dose and side effects"},"content":{"rendered":"\n<p>1%&nbsp;eye drops,&nbsp;atropine sulphate&nbsp;solution<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Isopto-Atropine is and what it is used for<\/h2>\n\n\n\n<p>Isopto-Atropine is a painkiller and pupil dilator.&nbsp;It is used in certain types of eye infections and to improve vision in some cases.<\/p>\n\n\n\n<p>Isopto-Atropine&nbsp;eye drops&nbsp;can be used for treatment in children from 6 years of age and in adults.<\/p>\n\n\n\n<p>Atropine sulphate contained in Isopto-Atropine may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Isopto-Atropine<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Isopto-Atropine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to atropine sulphate or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are allergic to a group of medicines called belladonna alkaloids (atropine belongs to this group)<\/li><li>if you have or think you may have&nbsp;narrow-angle glaucoma&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>Warnings and cautions<\/strong><\/p>\n\n\n\n<p>Talk to your doctor or pharmacist before using Isopto-Atropine.<\/p>\n\n\n\n<p>Talk to your doctor as the use of Isopto-Atropine may cause:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased pressure in the eye, especially if you have a shallow anterior&nbsp;chamber of the eye&nbsp;or a narrow anterior&nbsp;chamber angle&nbsp;.&nbsp;You should have your eye pressure checked regularly and even before starting treatment.<\/li><li>behavioral changes, especially in the elderly, but reactions can occur at any age.<\/li><li>photosensitivity.&nbsp;Protect your eyes in bright light.<\/li><\/ul>\n\n\n\n<p>If you have a fever or are in a hot climate, talk to your doctor before using Isopto-Atropine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If Isopto-Atropine 1% is given to children 6 years of age and older, consult your doctor.&nbsp;Serious&nbsp;side effects&nbsp;may occur with the use of this medicine in children, especially children with low weight, or children with Down syndrome, spastic paralysis,&nbsp;epilepsy&nbsp;or brain damage.&nbsp;See also &#8220;How to use Isopto-Atropine&#8221;.<\/li><li>children must be kept under close supervision for at least 30 minutes after the medicine has been given.<\/li><li>if Isopto-Atropine misses the eye, wash it off immediately.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Isopto-Atropine<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>In particular, tell your doctor if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>antihistamines&nbsp;(medicines for&nbsp;allergies&nbsp;)<\/li><li>antidepressants<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Isopto-Atropine should not be used during pregnancy unless clearly necessary.<\/p>\n\n\n\n<p>Isopto-Atropine should not be used during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>This type of medicine can cause drowsiness, blurred vision, and photosensitivity.&nbsp;If you get any of these, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and \/ or&nbsp;side effects&nbsp;.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Isopto-Atropine contains benzalkonium chloride and boric acid<\/h2>\n\n\n\n<p>This medicine contains 0.0035 mg benzalkonium chloride per drop equivalent to 0.1 mg \/ ml.<\/p>\n\n\n\n<p>Benzalkonium chloride can be absorbed by soft contact lenses and can discolor the contact lenses.&nbsp;Remove contact lenses before using the medicine and wait at least 15 minutes before re-inserting the contact lenses.<\/p>\n\n\n\n<p>Benzalkonium chloride can be irritating to the eyes, especially if you have dry eyes or problems with the cornea (the clear membrane at the front of the eye).&nbsp;If you experience irritation, tingling, or pain in the eye after using the medicine, consult a doctor.<\/p>\n\n\n\n<p>Do not use the medicine in children younger than 2 years as it contains boron and may cause impaired&nbsp;fertility&nbsp;in the future.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Isopto-Atropine<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Adults, including the elderly<\/strong><\/p>\n\n\n\n<p>1-2 drops 1-3 times daily.<\/p>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>Always use the lowest possible&nbsp;dose&nbsp;needed to give the desired effect.<\/p>\n\n\n\n<p><strong>Children (6 years and older)<\/strong><\/p>\n\n\n\n<p>1 drop 1-2 times daily in the eye.<\/p>\n\n\n\n<p>Always use the lowest possible&nbsp;dose&nbsp;needed to give the desired effect.<\/p>\n\n\n\n<p>See also the sections \u201cWarnings and Cautions;&nbsp;Children \u201d,\u201c If you have used too much Isopto-Atropine \u201dand\u201c Possible side effects \u201d.<\/p>\n\n\n\n<p>Use only Isopto-Atropine to drip into the eye (s).<\/p>\n\n\n\n<p><strong>How to use Isopto-Atropine correctly:<\/strong><\/p>\n\n\n\n<p>If the safety collar is loose after the cover has been removed, it must be removed before using the product.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19640722000049#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/20713596-c348-4470-a7ff-33d21603297a\" alt=\"User instructions\" title=\"User instructions\"\/><\/a><\/figure>\n\n\n\n<ol class=\"wp-block-list\"><li>Bring out the bottle of Isopto-Atropine.<\/li><li>Wash your hands and sit in front of a mirror.<\/li><li>Unscrew the cap on the bottle.<\/li><li>Hold the bottle facing down between your thumb and forefinger (Fig. 1).<\/li><li>Tilt your head back.&nbsp;Pull down the lower eyelid with a clean finger, until a &#8220;pocket&#8221; is formed between the lower eyelid and the eye.&nbsp;This is where the drop should be placed.<\/li><li>Move the bottle tip close to the eye.&nbsp;Use a mirror if it helps.<\/li><li>Avoid touching the eye or eyelid, surrounding areas or other surfaces with the drip tip.&nbsp;It may contaminate the eye drops in the bottle.<\/li><li>Do not squeeze the bottle.&nbsp;It is designed so that a light pressure on the bottom is all that is needed (Fig. 2).<\/li><li>Gently press on the bottom of the bottle to release one drop of Isopto-Atropine at a time (Figure 3).<\/li><li>After using Isopto-Atropine, close the eyelid and gently press with a finger in the corner of the eye at the nose for 2 minutes (Fig. 4).&nbsp;It helps prevent Isopto-Atropine from entering the rest of the body.<\/li><li>If you are using Isopto-Atropine in both eyes, repeat steps 5 through 10 for your other eye.<\/li><li>Tighten the bottle cap firmly immediately after use.<\/li><\/ol>\n\n\n\n<p>If a drop misses the eye, wipe it off immediately and try again.<\/p>\n\n\n\n<p>If you are taking other medicines in the form of&nbsp;eye drops&nbsp;or eye ointments, wait at least 5 minutes between each use of the medicine.&nbsp;Eye ointments should be used last.<\/p>\n\n\n\n<p><strong>If you use more Isopto-Atropine than you should<\/strong><\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has ingested the medicine by mistake, contact a doctor, hospital or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<p>If you have used too much Isopto-Atropine, rinse everything out with warm water.&nbsp;Do not drip in more drops until it is time for the next scheduled&nbsp;dose&nbsp;.<\/p>\n\n\n\n<p>Symptoms of overdose may include:&nbsp;redness&nbsp;and dry skin (children may get a rash), blurred vision, rapid and irregular&nbsp;heartbeat&nbsp;, fever, bloated abdomen in infants, seizures, hallucinations or loss of coordination.<\/p>\n\n\n\n<p><strong>If you forget to use Isopto-Atropine<\/strong><\/p>\n\n\n\n<p>Continue with the next&nbsp;dose&nbsp;as planned.&nbsp;However, if it is almost time for your next&nbsp;dose&nbsp;, skip the missed&nbsp;dose&nbsp;and return to your regular dosing schedule.<\/p>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/p>\n\n\n\n<p><strong>If you stop using Isopto-Atropine<\/strong><\/p>\n\n\n\n<p>Do not stop using this medicine prematurely, even if your symptoms have disappeared.&nbsp;If you stop using this medicine too soon, the symptoms may return.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects&nbsp;, although not everybody gets them.<\/p>\n\n\n\n<p>You may get the following reactions in your eyes:<\/p>\n\n\n\n<p><em>Common (affects 1 to 10 users in 100):<\/em>&nbsp;photosensitivity, eye pain and visual impairment.<\/p>\n\n\n\n<p><em>Rare (affects 1 to 10 users in 10,000):&nbsp;<\/em>narrow-angle glaucoma&nbsp;.<\/p>\n\n\n\n<p><em>No known frequency (can not be calculated from the available data):<\/em>&nbsp;swollen eyelids, blurred vision, increased pupil size (prolonged effect of the drug),&nbsp;conjunctivitis&nbsp;, red eyes, swollen eyes and watery eyes.<\/p>\n\n\n\n<p>Reactions in other parts of the body:<\/p>\n\n\n\n<p><em>Common (affects 1 to 10 users in 100):<\/em>&nbsp;hallucinations, confusion, agitation, increased heart rate, constipation,&nbsp;flushing&nbsp;and fever.<\/p>\n\n\n\n<p><em>No known frequency (can not be calculated from the available data)<\/em>&nbsp;:&nbsp;allergy&nbsp;, confusion, dizziness, headache, lack of coordination, incoherent speech, restlessness, hyperactivity, seizures, inability to recognize other people, abnormal drowsiness, slower heart rate, decreased&nbsp;blood pressure&nbsp;, dilation of blood vessels, difficulty breathing, intestinal blockage, bloating, vomiting, decreased intestinal motility, skin inflammation or&nbsp;redness&nbsp;, rash, difficulty urinating, decreased&nbsp;secretion&nbsp;in the salivary and sweat glands,&nbsp;pharynx&nbsp;,&nbsp;bronchi&nbsp;and nasal passages.<\/p>\n\n\n\n<p><strong>Additional&nbsp;side effects&nbsp;are in children<\/strong><\/p>\n\n\n\n<p>Children, especially children with low weight and children with&nbsp;central nervous system disorders&nbsp;(eg&nbsp;epilepsy&nbsp;, brain damage or Down syndrome) are at increased risk of toxic effects.&nbsp;This can manifest as&nbsp;central nervous system disorders&nbsp;(similar to those listed above, eg, inconsistent speech, restlessness, hallucinations, hyperactivity, confusion) and can cause very high fever.&nbsp;Toxic effects can also appear as disorders of the heart, lungs and stomach.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Isopto-Atropine<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>The bottle is discarded 4 weeks after opening.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is atropine sulphate 10 mg.<\/li><li>The other ingredients are benzalkonium chloride (&nbsp;preservative&nbsp;), hypromellose, boric acid, sodium hydroxide and \/ or&nbsp;hydrochloric acid&nbsp;for&nbsp;pH&nbsp;adjustment and purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Isopto-Atropine is a colorless solution supplied in a 5 ml plastic bottle (DROPTAINER) of LDPE with a screw cap.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Alcon Nordic A \/ S<\/p>\n\n\n\n<p>Edvard Thomsens Vej 14<\/p>\n\n\n\n<p>2300 Copenhagen S<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Alcon Laboratories Belgium<\/p>\n\n\n\n<p>Lichterveld 3<\/p>\n\n\n\n<p>2870 Puurs-Sint-Amands<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p>Or<\/p>\n\n\n\n<p>SA Alcon-Couvreur NV<\/p>\n\n\n\n<p>Rijksweg 14<\/p>\n\n\n\n<p>2870 Puurs<\/p>\n\n\n\n<p>Belgium<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Isopto-Atropine is a painkiller and pupil dilator. It is used in certain types of eye infections and to improve vision in some cases.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[12116,2200],"tags":[12233,12236,4501,12238,12241,12242,12237,12235,12234,12239,12240],"class_list":["post-14576","post","type-post","status-publish","format-standard","hentry","category-i","category-medicines","tag-atropine-sulphate","tag-atropine-sulphate-eye-drops","tag-eye-drops","tag-isopto-atropine","tag-isopto-atropine-eye-drops","tag-isopto-atropine-side-effects","tag-side-effects-of-atropine-sulphate","tag-what-atropine-sulphate-is-used-for","tag-what-is-atropine-sulphate","tag-what-is-isopto-atropine","tag-what-isopto-atropine-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14576","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14576"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14576\/revisions"}],"predecessor-version":[{"id":14736,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14576\/revisions\/14736"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14576"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14576"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14576"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}