{"id":14564,"date":"2021-10-04T15:52:49","date_gmt":"2021-10-04T15:52:49","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14564"},"modified":"2021-10-09T16:28:46","modified_gmt":"2021-10-09T16:28:46","slug":"isomex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/isomex\/","title":{"rendered":"Isomex &#8211; Isosorbide mononitrate uses, dose and side effects"},"content":{"rendered":"\n<p>30 mg&nbsp;prolonged-release tablet&nbsp;is<br>isosorbide mononitrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Isomex is and what it is used for<\/h2>\n\n\n\n<p>Isomex contains the active ingredient&nbsp;isosorbide mononitrate, which belongs to a group of medicines called nitrates.&nbsp;This type of medicine works by dilating the blood vessels, thereby facilitating the heart&#8217;s work in case of angina in the heart.<\/p>\n\n\n\n<p>Isomex is used to prevent angina in the heart (&nbsp;angina pectoris&nbsp;).<\/p>\n\n\n\n<p>Isosorbide mononitrate contained&nbsp;in Isomex may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Isomex<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Isomex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;isosorbide mononitrate&nbsp;or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are taking medicines to treat&nbsp;impotence&nbsp;or&nbsp;pulmonary&nbsp;arterial&nbsp;hypertension&nbsp;(PAH)&nbsp;at the same time&nbsp;;&nbsp;for example&nbsp;Viagra (sildenafil), Cialis (tadalafil), or Levitra (vardenafil).&nbsp;See section \u201cOther medicines and Isomex\u201d.<\/li><li>if you suffer from failing circulation (&nbsp;acute&nbsp;circulatory failure&nbsp;,&nbsp;shock&nbsp;)<\/li><li>if you have a disease in your heart muscle (constrictive&nbsp;cardiomyopathy&nbsp;)<\/li><li>if you have certain diseases of the pericardium (constrictive pericarditis, pericardial tamponade)<\/li><li>if you have early signs of a heart attack (chest pain or pressure over the chest, pain spreading to your jaw or shoulder, nausea, sweating).<\/li><li>if you are also taking riociguat.&nbsp;See section &#8220;Other medicines and Isomex&#8221;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Isomex<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you suffer from severely reduced blood flow to the brain<\/li><li>if you have any heart disease<\/li><li>if you have&nbsp;anemia&nbsp;(&nbsp;anemia&nbsp;)<\/li><li>if you have low blood oxygen (&nbsp;hypoxemia&nbsp;)<\/li><li>if you have unstable&nbsp;blood pressure&nbsp;such as low&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;) and decreased blood volume (&nbsp;hypovolemia&nbsp;)<\/li><li>if you have&nbsp;hypothyroidism&nbsp;(&nbsp;hypothyroidism&nbsp;)<\/li><li>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>This medicine is not intended for use in children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Isomex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.&nbsp;Some medicines may affect or be affected by treatment with Isomex.<\/p>\n\n\n\n<p>Do not use Isomex at the same time as medicines such as Viagra (sildenafil), Cialis (tadalafil), or Levitra (vardenafil), which are used for&nbsp;impotence&nbsp;(&nbsp;erectile dysfunction&nbsp;) or&nbsp;pulmonary&nbsp;arterial&nbsp;hypertension&nbsp;(PAH).&nbsp;If you are taking such a medicine while taking Isomex, it may cause a severe drop in blood pressure which may lead to fainting or heart attack.&nbsp;Do not use Isomex at the same time as riociguat as this may cause abnormally low levels&nbsp;<\/p>\n\n\n\n<p>of blood pressure.&nbsp;Isomex should not be used at the same time as dihydroergotamine as it may&nbsp;<\/p>\n\n\n\n<p>enhance the antihypertensive effect of dihydroergotamine.<\/p>\n\n\n\n<p>Drugs that dilate blood vessels or lower&nbsp;blood pressure&nbsp;can affect the effect of Isomex.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Isomex with food, drink and alcohol<\/h2>\n\n\n\n<p>Taking alcohol while taking Isomex may make your&nbsp;blood pressure&nbsp;worse&nbsp;and you may feel dizzy or faint.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>As a precautionary measure, it is best to avoid using Isomex during pregnancy.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>There is limited experience with the use of Isomex during pregnancy.&nbsp;Therefore, consult a doctor before taking Isomex during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>It is unknown whether&nbsp;isosorbide mononitrate is excreted&nbsp;in human milk.&nbsp;Risk to the breastfeeding child cannot be ruled out.&nbsp;Therefore, you should not use Isomex during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Isomex can cause headaches and dizziness.&nbsp;You should not drive, use advanced machines or engage in any other potentially hazardous activities until you know if this medicine affects your ability to perform these activities.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Isomex contains lactose<\/h2>\n\n\n\n<p>Isomex contains a sugar called&nbsp;lactose.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Isomex<\/h2>\n\n\n\n<p>Always take this medicine exactly as described in this leaflet or as your doctor advised.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Your doctor will decide which&nbsp;dose&nbsp;is right for you.&nbsp;The usual&nbsp;dose&nbsp;for adults is 60 mg (two tablets) of Isomex once daily in the morning.<\/p>\n\n\n\n<p>Your doctor may ask you to start with a lower&nbsp;dose&nbsp;so that the risk of you getting a headache when you start taking Isomex is less.&nbsp;Your doctor may prescribe a different&nbsp;dosage&nbsp;depending on your symptoms, your age, and other medicines you are taking.&nbsp;Dose&nbsp;one can be increased to 120 mg daily.<\/p>\n\n\n\n<p><em>Use for the elderly<\/em><\/p>\n\n\n\n<p>Dose&nbsp;one for elderly patients (over 65 years) is the same as for adults.<\/p>\n\n\n\n<p><strong>Method of administration<\/strong><\/p>\n\n\n\n<p>Isomex should be swallowed whole and must not be crushed or chewed.&nbsp;Always swallow the tablets with at least half a glass of water.&nbsp;The tablets can be taken with or without food.<\/p>\n\n\n\n<p>Sometimes some users may see remnants of the tablet in the stool.&nbsp;This is normal and does not mean that the medicine has not been absorbed into the body.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Isomex than you should<\/h2>\n\n\n\n<p>If you have ingested too much or if e.g.&nbsp;If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<p>Signs of overdose may include throbbing headache, nervousness,&nbsp;redness, cold sweats, nausea, vomiting, dizziness, fainting, and rapid&nbsp;heartbeat.&nbsp;If you suddenly experience any of the above, lie down with slightly raised legs as it can relieve the symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Isomex<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Isomex<\/h2>\n\n\n\n<p>Do not suddenly stop taking Isomex tablets as this may make your angina worse.&nbsp;If your treatment is to be stopped, this should be done gradually.&nbsp;Be sure to follow your doctor&#8217;s instructions.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you get any of the following symptoms as they may be severe;<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness, nausea (common, may affect up to 1 in 10 people)<\/li><li>fainting (rare, may affect up to 1 in 1,000 people)<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache that disappears or subsides with continued use<\/li><li>low&nbsp;blood pressure&nbsp;&#8211; which can cause dizziness and nausea<\/li><li>palpitations (&nbsp;tachycardia&nbsp;)<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting<\/li><li>diarrhea<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash,&nbsp;itching<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect less than 1 in 10,000 users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle pain (&nbsp;myalgia&nbsp;)<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Isomex<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;isosorbide mononitrate&nbsp;.&nbsp;Each tablet contains 30 mg of&nbsp;isosorbide mononitrate&nbsp;.<\/li><li>The other ingredients are: hypromellose,&nbsp;lactose monohydrate&nbsp;, pregelatinized&nbsp;starch&nbsp;, magnesium stearate, anhydrous&nbsp;colloidal&nbsp;silica.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Isomex tablets are white\/off-white, oval&nbsp;prolonged-release tablets.<\/p>\n\n\n\n<p>Isomex is available in a bottle containing 100 tablets or in a blister pack containing 28 or 98 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Recipharm Fontaine<\/p>\n\n\n\n<p>Rue de Pr\u00e8s Potets<\/p>\n\n\n\n<p>21121 Fontaine-l\u00e8s-Dijon<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>Astimex Pharma AB<\/p>\n\n\n\n<p>Isafjordsgatan 36<\/p>\n\n\n\n<p>164 40 Kista<\/p>\n\n\n\n<p>Tel.&nbsp;08-5151 1535<\/p>\n\n\n\n<p>info@astimex.se<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Sweden<br>Denmark<br>NorwayNetherlands<\/td><td>Isomex 30 mg prolonged-release tablets&nbsp;<br>Isomex, 30 mg&nbsp;prolonged-release tablet&nbsp;is<br>Isomex 30 mg&nbsp;prolonged-release tablet&nbsp;isIsosorbide Mononitrate&nbsp;Retard&nbsp;RPH 30 mg, controlled release tablets<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Isomex contains the active ingredient isosorbide mononitrate, which belongs to a group of medicines called nitrates. This type of medicine works by dilating the blood vessels, thereby facilitating the heart&#8217;s work in case of angina in the heart.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[12116,2200],"tags":[12263,12266,12209,12213,12267,12219,2210,12264,12210,12265,12211],"class_list":["post-14564","post","type-post","status-publish","format-standard","hentry","category-i","category-medicines","tag-isomex","tag-isomex-tablet","tag-isosorbide-mononitrate","tag-isosorbide-mononitrate-tablet","tag-side-effects-of-isomex","tag-side-effects-of-isosorbide-mononitrate","tag-tablet","tag-what-is-isomex","tag-what-is-isosorbide-mononitrate","tag-what-isomex-is-used-for","tag-what-isosorbide-mononitrate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14564","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14564"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14564\/revisions"}],"predecessor-version":[{"id":14741,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14564\/revisions\/14741"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14564"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14564"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14564"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}