{"id":14471,"date":"2021-10-01T05:53:19","date_gmt":"2021-10-01T05:53:19","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14471"},"modified":"2022-12-24T08:18:37","modified_gmt":"2022-12-24T08:18:37","slug":"ipramol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ipramol\/","title":{"rendered":"Ipramol &#8211; Ipratropium Bromide \/ Salbutamol Sulfate Uses, Dose And Side Effects"},"content":{"rendered":"\n<p>Ipramol 0.5 mg \/ 2.5 mg per 2.5 mL,&nbsp;solution&nbsp;nebulizer<br>ipratropium bromide, salbutamol sulfate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Ipramol Is And What Is Ipramol Used For<\/h2>\n\n\n\n<p>Your medicine is called Ipramol.\u00a0The active substances are ipratropium bromide and\u00a0salbutamol\u00a0.\u00a0Both ipratropium bromide and\u00a0salbutamol\u00a0belong to a class of medicines called\u00a0bronchodilators, which facilitate breathing by widening the airways.\u00a0The smooth muscles surrounding the airways are prevented from contracting; thus, the airways are kept open.\u00a0Ipratropium bromide works by blocking the nerve signals sent to the muscles that surround the airways, and\u00a0salbutamol\u00a0works by stimulating specific\u00a0receptors\u00a0in the muscles.<\/p>\n\n\n\n<p>Ipramol is used to treat breathing problems in people who have long-term breathing difficulties due to a disease called &#8220;chronic obstructive pulmonary disease&#8221; or &#8220;COPD.&#8221;\u00a0Ipramol relieves wheezing, shortness of breath, and tightness in the chest by dilating your airways.<\/p>\n\n\n\n<p>Ipratropium bromide and\u00a0salbutamol\u00a0contained in Ipramol may also be approved for treating other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before You Use Ipramol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Ipramol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to ipratropium bromide or\u00a0salbutamol,\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you are allergic to medicines containing atropine or similar medicines<\/li><li>If you have heart rhythm disorders, e.g.,\u00a0fast\u00a0pulse\u00a0or palpitations (called\u00a0tachyarrhythmia\u00a0)<\/li><li>If you know that your heart is enlarged or you have a condition called\u00a0hypertrophic\u00a0obstructive\u00a0cardiomyopathy, the wall between the two sides of the heart becomes thicker and blocks blood flow.<\/li><\/ul>\n\n\n\n<p>If unsure, talk to your doctor or pharmacist before taking Ipramol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Ipramol:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have or think you may have an eye disease called\u00a0glaucoma\u00a0(increased pressure in the eyes) or any other eye disease.\u00a0Your doctor may recommend that you protect your eyes while using Ipramol;<\/li><li>If you are a man and know that you have an enlarged\u00a0prostate\u00a0or if you have problems emptying your bladder (urinating);<\/li><li>If you have recently had a heart attack,\u00a0if you have other vascular problems or get leg <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> when you walk;<\/li><li>If you have previously had heart disease, irregular heartbeat, or angina (angina), tell your doctor before taking this medicine;<\/li><li>If you have <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">diabetes<\/a>;<\/li><li>If you have an overactive thyroid gland;<\/li><li>If you have cystic fibrosis;<\/li><li>If you have been informed that you have an adrenal tumor.<\/li><\/ul>\n\n\n\n<p>A condition called lactic acidosis (increased acidity (\u00a0lactic acid\u00a0) in the blood) has been reported with high\u00a0doses\u00a0of\u00a0salbutamol, especially in patients being treated for\u00a0acute\u00a0bronchospasm\u00a0(tracheal spasm) (see sections 3 and 4).\u00a0An increase in lactate levels (lactic acid level) can lead to difficulty breathing and hyperventilation (rapid and shallow breathing), even if other symptoms, such as wheezing, improve.\u00a0If you experience that your medicine does not work as well as usual and you need to use the<strong> Ipramol nebulizer <\/strong>more than your doctor has prescribed, talk to a doctor immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>Ipramol is not recommended for use in children 12 years of age or younger as safety and efficacy have not been established in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Ipramol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Some medicines can affect Ipramol and aggravate the&nbsp;side effects&nbsp;or weaken the effect of Ipramol.&nbsp;You must tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other asthma medications, including\u00a0inhalers\u00a0and\u00a0asthma\u00a0tablets.\u00a0This applies to medicines used &#8220;as needed,&#8221; such as\u00a0salbutamol, and &#8220;preventive medicine,&#8221; such as beclomethasone dipropionate.\u00a0These drugs may increase the effect of Ipramol and aggravate the side effects;<\/li><li>Beta-blockers, i.e., medicines commonly used for heart problems, such as <ul><li>Chest pain during exertion (angina pectoris)<\/li><li>Irregular heartbeat or\u00a0arrhythmias<\/li><li>High\u00a0blood pressure.\u00a0These medications include drugs such as propranolol.\u00a0These drugs inhibit Ipramol&#8217;s bronchodilator effect;<\/li><\/ul><\/li><li>Certain drugs are used to treat <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">depression<\/a> and anxiety, so-called &#8220;antidepressants.&#8221;\u00a0This class of drugs includes medicines such as\u00a0monoamine oxidase inhibitors\u00a0(e.g., phenelzine) and\u00a0tricyclic antidepressants\u00a0(e.g., amitriptyline);<\/li><li>Digoxin\u00a0(for heart problems) can cause heart rhythm problems when given with Ipramol;<\/li><li>diuretics\u00a0(&#8221;\u00a0diuretics\u00a0&#8220;) and steroid tablets(medicines that reduce\u00a0inflammation\u00a0such as\u00a0prednisolone\u00a0).\u00a0These drugs may increase the risk of decreased potassium in the blood;<\/li><li>Anesthetics can increase the sensitivity to the effect of salbutamol on the heart &#8211; you will be closely monitored, and your doctor may decide to discontinue Ipramol if you are having surgery.<\/li><\/ul>\n\n\n\n<p>If you are going to have an operation under anesthesia, you must tell the anesthetist which medicines you are taking.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ipramol With Food And Drink<\/h2>\n\n\n\n<p>Intake of food and drink does not affect Ipramol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Ipramol should not be used during pregnancy or breastfeeding unless your doctor decides that the benefits to the mother outweigh the risks to the baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Ipramol may cause dizziness, and you may have difficulty focusing or blurred vision.\u00a0If this happens to you, do not drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use Ipramol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Ipramol inhalation<\/strong> is used after nebulization.<\/li><li>Always take Ipramol exactly as your doctor or pharmacist has told you.\u00a0If you are not sure, talk to your doctor or nurse.<\/li><li>The recommended\u00a0dose\u00a0for adults and children over 12 years of age consists of one\u00a0ampoule three or four times a day.<\/li><li>Elderly patients should take the normal adult dose.<\/li><li><strong>Ipramol inhalation<\/strong> is\u00a0not\u00a0recommended\u00a0for children under 12 years of age.<\/li><li>The label says how much you should take and how often.<\/li><\/ul>\n\n\n\n<p><strong>Never take more medicine than your doctor has prescribed.\u00a0Tell your doctor if your breathing problems worsen, if the medicine does not alleviate your breathing problems as much as before, or if you use your blue short-acting\u00a0inhaler\u00a0with &#8220;on-demand medicine&#8221; more often than usual.<\/strong><\/p>\n\n\n\n<p><strong>Instructions for use<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Prepare the nebulizer according to the manufacturer&#8217;s and physician&#8217;s instructions.<\/li><li>Carefully twist and pull a new\u00a0ampoule\u00a0from the\u00a0ampoule\u00a0map (Fig. A).\u00a0Never use medicines from an\u00a0ampoule\u00a0that has been opened before or if the solution is discolored.<\/li><li>Hold the\u00a0ampoule\u00a0upright and turn off the top (picture B).<\/li><li>Squeeze the contents into the nebulizer chamber (Fig. C).<\/li><li>Prepare and use the <strong> Ipramol nebulizer <\/strong>according to the manufacturer&#8217;s and physician&#8217;s instructions.<\/li><li>After using the nebulizer, discard any solution remaining in the chamber.\u00a0Also, discard any solution that may remain in the\u00a0ampoule.<\/li><li>Thoroughly clean the nebulizer according to the manufacturer&#8217;s instructions.\u00a0It is important to keep the <strong> Ipramol nebulizer <\/strong>clean.<\/li><\/ul>\n\n\n\n<p>Do not dilute or mix the solution with other medicines unless your doctor tells you to.<br>Endosampullerna with Ipramol contains no\u00a0preservatives; therefore, it is important to use the contents as soon as the\u00a0ampoule\u00a0is opened.\u00a0When you use Ipramol in your\u00a0nebulizer, you must use a new\u00a0ampoule.<br>You should be discarded if a partly used, opened, or damaged Ipramol-\u00a0cartridge is present.\u00a0<strong>Never<\/strong>\u00a0use\u00a0an\u00a0ampoule\u00a0that has been opened before.<\/p>\n\n\n\n<p>You must follow these instructions so as not to contaminate the solution in the\u00a0ampoules.<\/p>\n\n\n\n<p>Swallow\u00a0<strong>is not<\/strong>\u00a0the solution, and uses it for\u00a0injection.<\/p>\n\n\n\n<p>The solution or mist from the solution must&nbsp;<strong>not<\/strong>&nbsp;get into the eyes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Ipramol Than You Should<\/h2>\n\n\n\n<p>If you have taken a slightly larger\u00a0dose\u00a0than usual, you may experience a faster heartbeat (palpitations) or tremors.\u00a0Other symptoms may include <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest pain<\/li><li>High blood pressure<\/li><li>Hot flashes<\/li><li>Restlessness<\/li><li>Dizziness<\/li><\/ul>\n\n\n\n<p>These effects usually go away in a couple of hours.\u00a0The potassium level in the blood can drop; the doctor may sometimes want to take blood samples to check the potassium level.\u00a0Tell your doctor if you are worried about any of these symptoms or if they persist.<\/p>\n\n\n\n<p>If you have taken more medicine than you should, tell your doctor immediately or go to the nearest hospital.\u00a0If you need to go to a doctor or hospital, take all the medicines you take with you, even those you bought without a prescription.\u00a0If possible, take the medicines in their original packaging.\u00a0Take this leaflet with you and show it to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Ipramol<\/h2>\n\n\n\n<p><strong>Ipramol dose<\/strong><\/p>\n\n\n\n<p>If you forget to take a\u00a0dose\u00a0at the right time, take it as soon as you find that you have forgotten to take a\u00a0dose.\u00a0Do not take a double\u00a0<strong>Ipramol dose\u00a0<\/strong>to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Using Ipramol<\/h2>\n\n\n\n<p>It would help if you did not stop using Ipramol without first discussing it with your doctor.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Ipramol Side Effects<\/h2>\n\n\n\n<p>Ipramol can cause side effects like all medicines, although not everybody gets them.\u00a0Some of the\u00a0side effects\u00a0can be serious and require medical attention.<\/p>\n\n\n\n<p><strong>Serious\u00a0ipramol side effects\u00a0are<\/strong><br>If your asthma or wheezing worsens immediately after inhaling Ipramol, or if you find it harder to breathe and get short of breath, you should not take more Ipramol.\u00a0Use your short-acting\u00a0inhaler\u00a0with &#8220;on-demand medicine&#8221;\u00a0immediately.\u00a0You should stop using Ipramol and contact your doctor immediately.\u00a0Your doctor may\u00a0prescribe\u00a0another treatment for your condition.<\/p>\n\n\n\n<p>If you get pain or irritation in your eyes, blurred vision, or red eyes, or if you see light rings (halophenomas) or colored dots, you should contact a doctor immediately as these symptoms may need to be treated.<\/p>\n\n\n\n<p>If you think you may be allergic to Ipramol or if you think you may have had an&nbsp;allergic reaction&nbsp;to the solution, stop taking Ipramol immediately and contact your doctor.<\/p>\n\n\n\n<p>Ipramol contains\u00a0salbutamol, which can lower the level of potassium in the blood (\u00a0hypokalaemia\u00a0) and can cause muscle weakness, twitching, or abnormal heart rhythm.\u00a0This is more likely to happen if you use Ipramol with another asthma treatment,\u00a0inhaled steroids, steroid tablets, or\u00a0diuretics\u00a0(&#8221;\u00a0diuretics\u00a0&#8220;).\u00a0Your doctor may sometimes need a blood test to check your potassium levels.<\/p>\n\n\n\n<p><strong>Frequency of&nbsp;<\/strong><strong>side effects<\/strong><br><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Palpitations or fast\u00a0pulse<\/li><li>Dry mouth<\/li><li>Nausea<\/li><li>Mouth and throat irritation<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">Cough<\/a><\/li><li>Speech difficulties<\/li><li>Dizziness<\/li><li>High\u00a0blood pressure<\/li><li>Restlessness<\/li><li>Tremors<\/li><li>Difficulty emptying the bladder (urination)<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reactions, including swelling of the tongue, lips, and face<\/li><li>Difficulty breathing and shortness of breath<\/li><li>Sweating<\/li><li>Hot flashes<\/li><li>Lowered\u00a0blood pressure<\/li><li>Irregular heartbeat<\/li><li>Chest pain (due to heart problems)<\/li><li>Vomiting<\/li><li>Stomach upset (including intestinal obstruction)<\/li><li>Itching<\/li><li>Rash<\/li><li>Muscle pain, muscle weakness, and muscle cramps<\/li><li>Memory disorders<\/li><li>Anxiety<\/li><li>Hyperactivity in children<\/li><li>Eye pain or other eye problems, including <ul><li>Burred vision<\/li><li>Severe pupillary enlargement<\/li><li>Glaucoma\u00a0(increased pressure in the eyes)<\/li><\/ul><\/li><li>Low potassium levels in the blood<\/li><\/ul>\n\n\n\n<p>Although it is not known exactly how often it occurs, some people can sometimes experience chest pain (caused by heart problems such as angina).\u00a0Tell your doctor as soon as possible if you get these symptoms while being treated with Ipramol, but do not stop the treatment unless your doctor recommends it.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have also been reported and occur in an unknown number of users:<\/p>\n\n\n\n<p>A condition called lactic acidosis (increased acidity (\u00a0lactic acid\u00a0)) can cause <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abdominal pain<\/li><li>Hyperventilation (rapid and shallow breathing)<\/li><li>Difficulty breathing (although other symptoms such as wheezing improve)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Cold<\/a> hands and feet<\/li><li>Irregular heartbeat<\/li><li>Thirst<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you get any side effects.\u00a0This also applies to any side effects not mentioned in this information.\u00a0You can also report side effects directly to the Medical Products Agency.\u00a0By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Ipramol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the carton.\u00a0The expiration date is the last day of the specified month.<\/li><li>Store in the outer carton.\u00a0Sensitive to light.\u00a0Do not store above 25 \u00b0 C.\u00a0Do not freeze.<\/li><li>Do not use this medicine if the solution is discolored or cloudy.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are: 0.5 mg ipratropium bromide (as monohydrate) and 2.5 mg\u00a0salbutamol\u00a0(as sulfate);<\/li><li>The other ingredients are: sodium chloride, injection water, and dilute\u00a0hydrochloric acid.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p>Each&nbsp;plastic ampoule&nbsp;of Ipramol contains a clear solution.&nbsp;Cards with 5&nbsp;ampoules&nbsp;are packed in foil bags, which in turn are packed in cardboard boxes containing 5, 10, 15, 20, 25, 30, 40, 50, 60, or 60 (2 cartons of 30&nbsp;ampoules&nbsp;)&nbsp;ampoules&nbsp;with Ipramol.<br>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>IVAX Pharmaceuticals UK, Preston Brook, Runcorn, Cheshire, WA7 3FA, UK<\/p>\n\n\n\n<p>Merckle GmbH, Ludwig-Merckle-Str.&nbsp;3, 89143 Blaubeuren, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ipramol Steri-Neb is used to treat breathing difficulties in people with long-standing breathing problems in an infection called &#8216;chronic obstructive pulmonary condition&#8217; or &#8216;COPD.&#8217; Ipramol Steri-Neb will relieve wheezing, shortness of breath, and chest tightness by opening up your airways.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[12464,12443,12459,12461,6729,12456,12460,12465,9678,12463,9676,12462,6730,12457,12458],"class_list":["post-14471","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-ipramol","tag-benefits-of-ipratropium-bromide","tag-benefits-of-salbutamol-sulfate","tag-ipramol","tag-ipratropium-bromide","tag-salbutamol-sulfate","tag-salbutamol-sulfate-side-effects","tag-side-effects-of-ipramol","tag-side-effects-of-ipratropium-bromide","tag-what-ipramol-is-used-for","tag-what-ipratropium-bromide-is-used-for","tag-what-is-ipramol","tag-what-is-ipratropium-bromide","tag-what-is-salbutamol-sulfate","tag-what-salbutamol-sulfate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14471","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14471"}],"version-history":[{"count":46,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14471\/revisions"}],"predecessor-version":[{"id":41343,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14471\/revisions\/41343"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14471"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14471"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14471"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}