25 mg or 50 mg film-coated tablets
eplerenone<\/p>\n\n\n\n
Inspra belongs to a group of medicines called selective aldosterone antagonists. These antagonists inhibit the effect of aldosterone, a substance that the body produces to regulate blood pressure and heart function. High levels of aldosterone can cause changes in the body that lead to heart failure.<\/p>\n\n\n\n
Inspra is used to treat your heart failure to prevent worsening and reduce the number of hospital stays if you have:<\/p>\n\n\n\n
Eplerenone contained in Inspra may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n
Talk to a doctor, pharmacist, or nurse before taking Inspra<\/strong> :<\/p>\n\n\n\n The safety and efficacy of eplerenone in children and adolescents have not been established.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n Inspra<\/strong> can be taken with or without food.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. The effect of Inspra<\/strong> during human pregnancy has not been studied.<\/p>\n\n\n\n It is not known whether eplerenone is excreted in human breast milk. Discuss with your doctor before deciding whether to stop breastfeeding or stop taking the medicine.<\/p>\n\n\n\n You may feel dizzy after taking Inspra<\/strong>. In this case, do not drive, use any tools or machines.<\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n Inspra contains lactose monohydrate lactose (a sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n Inspra contains less than 1 mmol (23 mg) sodium per tablet, ie it is essentially ‘sodium-free.<\/p>\n\n\n\n Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n Inspra<\/strong> can be taken with food or on an empty stomach. Swallow the tablets whole along with a copious amount of liquid.<\/p>\n\n\n\n Inspra<\/strong> is normally given together with other medicines for heart failure, such as beta-blockers. The usual starting dose is 25 mg once a day, which after about 4 weeks is increased to 50 mg once a day (either as a 50 mg tablet or two 25 mg tablets). The maximum dosage is 50 mg daily.<\/p>\n\n\n\n Potassium levels in the blood should be checked before treatment with Inspra<\/strong>, during the first week of treatment, and one month after starting a treatment or changing the dose.<\/p>\n\n\n\n Dose one may need to be adjusted by your doctor, depending on the potassium levels in your blood.<\/p>\n\n\n\n If you have mild renal impairment, you should start with a 25 mg tablet every day. And if you have moderate renal impairment, you should start with a 25 mg tablet every other day. These doses can be adjusted if your doctor recommends so and based on the levels of potassium in your blood.<\/p>\n\n\n\n Inspra<\/strong> is not recommended for patients with severe renal impairment.<\/p>\n\n\n\n The starting dose does not need to be adjusted in patients with mild to moderate hepatic impairment. If you have liver or kidney problems, your potassium levels in the blood may need to be checked more often (see also “Do not take Inspra<\/strong> “).<\/p>\n\n\n\n Elderly: No adjustment of the starting dose is required.<\/p>\n\n\n\n Children and adolescents: Inspra<\/strong> is not recommended.<\/p>\n\n\n\n If you have ingested too much medicine or if e.g. If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n If you have taken too much of your medicine, the most likely symptoms will be low blood pressure (may manifest as a “slight” feeling in your head, dizziness, blurred vision, weakness, acute unconsciousness) or hyperkalemia, elevated levels of potassium in the blood. (may manifest as muscle cramps, diarrhea, nausea, dizziness, or headache).<\/p>\n\n\n\n If it is soon time for your next dose, skip the missed tablet and take the next one as usual.<\/p>\n\n\n\n Otherwise, take it as soon as you remember, provided it takes more than 12 hours for you to take the next tablet. Then return to your regular medication.<\/p>\n\n\n\n Do not take a double dose to make up for a forgotten tablet.<\/p>\n\n\n\n It is important to continue taking Inspra<\/strong> as prescribed unless your doctor tells you to stop your treatment.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n If you experience any of the following:<\/p>\n\n\n\n Should you seek immediate medical attention:<\/strong><\/p>\n\n\n\n These are symptoms of angioneurotic edema, a less common (affects up to 1 in 100 people) side effect.<\/p>\n\n\n\n Other reported side effects include:<\/p>\n\n\n\n Common side effects are<\/strong> (may affect up to 1 in 10):<\/p>\n\n\n\n Less common side effects are<\/strong> (may affect up to 1 in 100):<\/p>\n\n\n\n Reporting of side effects<\/em><\/p>\n\n\n\n If you get any side effects, talk to your doctor, pharmacist, or nurse. This also applies to any side effects not mentioned in this information. You can also report side effects directly to the Medical Products Agency. By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n Keep out of sight and reach of children.<\/p>\n\n\n\n No special storage instructions.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. dat \u201dor\u201c EXP \u201d. The expiration date is the last day of the specified month.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substance in Inspra<\/strong> film-coated tablets is eplerenone. One tablet contains 25 mg or 50 mg of eplerenone.<\/p>\n\n\n\n The other ingredients are lactose monohydrate, microcrystalline cellulose (E460), croscarmellose sodium (E468), hypromellose (E464), sodium lauryl sulphate, talc (E553b), and magnesium stearate (E470b).<\/p>\n\n\n\n The tablet coating of Inspra<\/strong> consists of hypromellose (E464), titanium dioxide (E171), macrogol 400, polysorbate 80 (E433), yellow iron oxide (E172), and red iron oxide (E172).<\/p>\n\n\n\n Inspra<\/strong> 25 mg tablet is yellow and film-coated. The tablets are marked with “Pfizer” on one side of the tablet and “NSR” over “25” on the other side.<\/p>\n\n\n\n Inspra<\/strong> 50 mg tablet is yellow and film-coated. The tablets are marked with “Pfizer” on one side of the tablet and “NSR” above “50” on the other side.<\/p>\n\n\n\n Inspra<\/strong> 25 mg and 50 mg film-coated tablets are available in opaque PVC \/ Al pressure packs of 10, 20, 28, 30, 50, 90, 100 and 200 tablets respectively and in opaque PVC \/ Al perforated unit dose blisters containing 10×1, 20×1, 30×1, 50×1, 90×1, 100×1 or 200×1 (10 packs of 20×1) tablets. However, not all pack sizes will be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder:<\/p>\n\n\n\n Upjohn EESV<\/p>\n\n\n\n Rivium Westlaan 142<\/p>\n\n\n\n 2909 LD Capelle aan den IJssel<\/p>\n\n\n\n Netherlands<\/p>\n\n\n\n Local representative:<\/p>\n\n\n\n Pfizer AB<\/p>\n\n\n\n 191 90 Sollentuna<\/p>\n\n\n\n Tel: 08-550 520 00<\/p>\n\n\n\n Email: eumedinfo@pfizer.com<\/p>\n\n\n\n Manufacturer:<\/p>\n\n\n\n Fareva Amboise<\/p>\n\n\n\n Industrial Zone<\/p>\n\n\n\n 29 route des Industries<\/p>\n\n\n\n 37530 Poc\u00e9-sur-Cisse<\/p>\n\n\n\n France<\/p>\n","protected":false},"excerpt":{"rendered":" Inspra belongs to a group of medicines called selective aldosterone antagonists. These antagonists inhibit the effect of aldosterone, a substance that the body produces to regulate blood pressure and heart function. High levels of aldosterone can cause changes in the body that lead to heart failure.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[12686,12692,3996,12685,12688,12691,12687,12693,12684,12690,3997,12689],"class_list":["post-14376","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-eplerenone","tag-benefits-of-inspra","tag-eplerenone","tag-eplerenone-tablet","tag-inspra","tag-inspra-tablet","tag-side-effects-of-eplerenone","tag-side-effects-of-inspra","tag-what-eplerenone-is-used-for","tag-what-inspra-is-used-for","tag-what-is-eplerenone","tag-what-is-inspra"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14376","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14376"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14376\/revisions"}],"predecessor-version":[{"id":14916,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14376\/revisions\/14916"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14376"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14376"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14376"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Children and young people<\/h2>\n\n\n\n
Other medicines and Inspra<\/h2>\n\n\n\n
Inspire with food, drink and alcohol<\/h2>\n\n\n\n
Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Inspra contains lactose<\/h2>\n\n\n\n
3. How to use Inspra<\/h2>\n\n\n\n
If you use too much of Inspra <\/h2>\n\n\n\n
If you forget to use Inspra<\/h2>\n\n\n\n
If you stop using Inspra<\/h2>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
5. How to store Inspra<\/h2>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n