{"id":14231,"date":"2021-09-27T07:24:10","date_gmt":"2021-09-27T07:24:10","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14231"},"modified":"2021-10-18T07:59:36","modified_gmt":"2021-10-18T07:59:36","slug":"imolopesim","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/imolopesim\/","title":{"rendered":"Imolopesim &#8211; Loperamide hydrochloride \/ Dimethicone uses, dose and side effects"},"content":{"rendered":"\n<p>2 mg \/ 125 mg&nbsp;tablets<br>loperamide hydrochloride \/ dimethicone<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Imolopesim is and what it is used for<\/h2>\n\n\n\n<p>Imolopesim is used to treat temporary diarrhea when the diarrhea is associated with stomach cramps, bloating, and flatulence.<\/p>\n\n\n\n<p>The tablets contain two active substances:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>loperamide hydrochloride, which helps reduce diarrhea by normalizing excessive bowel movements.&nbsp;It also helps the body absorb more water and salts from the gut.<\/li><li>dimethicone, which dissolves the gas that is trapped in the intestine and which causes stomach cramps and bloating.<\/li><\/ul>\n\n\n\n<p>Imolopesim is used in adults and adolescents over 12 years of age.<\/p>\n\n\n\n<p>You must talk to a doctor if you do not feel better or if you feel worse after two days.<\/p>\n\n\n\n<p>Loperamide hydrochloride\/dimethicone (simethicone) contained in Imolopesim may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Imolopesim<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Imolopesim<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>to a child under 12 years of age.<\/li><li>if you are allergic to loperamide hydrochloride, dimethicone (simethicone) or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have a high fever (eg above 38 \u00b0 C) or blood in the stool.<\/li><li>if you have a flare-up of&nbsp;inflammatory&nbsp;bowel disease such as&nbsp;ulcerative colitis&nbsp;.<\/li><li>if you have severe diarrhea after using&nbsp;antibiotics&nbsp;.<\/li><li>if you are constipated or your stomach appears to be swollen.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Imolopesim:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Imolopesim only treats the symptoms of diarrhea.&nbsp;In some cases, the cause of your diarrhea may require treatment.&nbsp;If symptoms persist or worsen, consult your doctor.<\/li><li>If you have severe diarrhea, because your body loses more fluid, sugar and salts than normal.&nbsp;You need to replace the fluid by drinking more fluid than usual.&nbsp;Ask your pharmacy staff about special liquid substitutes to replace sugar and salts.<\/li><li>If you have&nbsp;AIDS&nbsp;and your stomach swells, stop taking the tablets immediately and contact your doctor.<\/li><li>If you have liver disease, you should consult your doctor before using the tablets.&nbsp;Some of the&nbsp;side effects&nbsp;can be more bothersome.<\/li><\/ul>\n\n\n\n<p>Do not take this medicine for anything other than its intended use (see section 1) and never take more than the recommended dose (see section 3).&nbsp;Severe heart problems (with symptoms such as fast or irregular heartbeat) have been reported in patients who have taken too much loperamide, the active substance in Imolopesim.<\/p>\n\n\n\n<p>In case of temporary diarrhea, the symptoms usually stop within 2 days.&nbsp;If symptoms persist after that period, discontinue treatment and consult a physician.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Imolopesim<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines including:&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Quinidine&nbsp;(used to treat abnormal heart rhythm or&nbsp;malaria&nbsp;)<\/li><li>Itraconazole or&nbsp;ketoconazole&nbsp;(&nbsp;antifungal&nbsp;)<\/li><li>Gemfibrozil (used to treat high&nbsp;cholesterol&nbsp;)<\/li><li>Ritonavir (used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;and&nbsp;AIDS&nbsp;)<\/li><li>Desmopressin (used to control thirst and urine output in patients with&nbsp;diabetes insipidus&nbsp;)<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, as Imolopesim may&nbsp;interact&nbsp;with&nbsp;you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, fertility<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Breast-feeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Do not take this medicine without consulting a doctor if you are breast-feeding, as small amounts of the medicine may pass into the milk.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>This medicine may make you feel dizzy, tired, or drowsy.&nbsp;If you notice this, do not drive or use any machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Imolopesim contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie it is essentially &#8216;sodium-free.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Imolopesim<\/h2>\n\n\n\n<p>Always take this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swallow the right number of tablets whole with water.<\/li><li>Do not use more than the recommended&nbsp;dose&nbsp;.<\/li><li>The notch is only for you to be able to divide the tablet if you have difficulty swallowing it whole.&nbsp;<\/li><\/ul>\n\n\n\n<p><strong>Use for adults over 18 years<\/strong><\/p>\n\n\n\n<p>Take 2 tablets first and then 1 tablet after each loose stool.&nbsp;Take a maximum of 4 tablets per day for a maximum of 2 days.&nbsp;If you do not get better after 2 days, stop taking the tablets and contact your doctor.<\/p>\n\n\n\n<p><strong>Use for young people between 12 and 18 years<\/strong><\/p>\n\n\n\n<p>Take 1 tablet first and then 1 tablet after each loose stool.&nbsp;Take a maximum of 4 tablets per day for a maximum of 2 days.&nbsp;If you do not get better after 2 days, stop taking the tablets and contact your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents under 12 years of age<\/h2>\n\n\n\n<p>Do not give the tablets to children under 12 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Imolopesim than you should<\/h2>\n\n\n\n<p>If you take more Imolopesim than you should, contact your doctor or hospital immediately for advice.&nbsp;Symptoms may include increased heart rate, irregular heartbeat, changes in a heartbeat (these symptoms can potentially have serious, life-threatening consequences), muscle stiffness, uncoordinated movements, drowsiness, difficulty urinating, or poor breathing.&nbsp;You may become dry in the mouth or have reduced&nbsp;pupils.&nbsp;You may have a stomach ache, feel sick or vomit or become constipated.<\/p>\n\n\n\n<p>Children react more strongly than adults to large amounts of Imolopesim.&nbsp;Contact a doctor immediately if a child has ingested too much of the medicine or has any of the above symptoms.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;a child inhaled the medicine accidentally contact a doctor, hospital, or the Poison Information Center for risk assessment and advice<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Imolopesim<\/h2>\n\n\n\n<p>Take one tablet after the next loose stool.<\/p>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p><strong>If you get any of the following&nbsp;side effects, stop using the medicine and seek medical advice immediately:<\/strong><\/p>\n\n\n\n<p>Allergic reactions to the symptoms<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, tongue or throat<\/li><li>difficulty swallowing<\/li><li>inexplicable hissing sound when breathing, shortness of breath that may be accompanied by skin rash or hives.<\/li><\/ul>\n\n\n\n<p><strong>If you get any of the following&nbsp;side effects, stop using this medicine and talk to your doctor:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty throwing water<\/li><li>Severe abdominal pain, bulging or swollen stomach or fever which may be a sign of blocked or enlarged bowel<\/li><li>Severe constipation.<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;that may occur<\/strong><\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache, nausea, or a changed experience of how certain things taste.<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drowsiness, dizziness, weakness, constipation.&nbsp;<\/li><li>vomiting, indigestion, flatulence,&nbsp;dry mouth&nbsp;, rash.&nbsp;<\/li><\/ul>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Unconsciousness or decreased level of consciousness, small&nbsp;pupils&nbsp;, skin rash that can lead to severe blistering and skin detachment, hives,&nbsp;itching&nbsp;, fatigue.&nbsp;<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency. By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Imolopesim<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substances are:<\/p>\n\n\n\n<p>Loperamide hydrochloride (2 mg per tablet) and simethicone equivalent to 125 mg dimethicone per tablet.<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p>microcrystalline cellulose (E460), sodium starch glycolate, hypromellose (E464), povidone (E2101), calcium phosphate (E341), mannitol (E421), and magnesium stearate (E572).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>The tablets are white to off-white capsule-shaped tablets with \u201cLO-SI\u201d debossed on one side and \u201c2\u201d and \u201c125\u201d debossed on the other side, on either side of a breaker.<\/p>\n\n\n\n<p>Each pack contains 6, 8, 10, 12, 15, or 16 tablets in blister strips.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Orifarm Generics A \/ S<\/p>\n\n\n\n<p>Energivej 15<\/p>\n\n\n\n<p>5260 Odense S<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Local representative:<\/strong><\/p>\n\n\n\n<p>Orifarm Generics AB,<\/p>\n\n\n\n<p>Box 56048<\/p>\n\n\n\n<p>102 17 Stockholm<\/p>\n\n\n\n<p>info@orifarm.com<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>NL: Losidaru<\/p>\n\n\n\n<p>DK: Imolopesim<\/p>\n\n\n\n<p>SE: Imolopesim<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imolopesim is used to treat temporary diarrhea when the diarrhea is associated with stomach cramps, bloating, and flatulence.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[12979,12973,12971,5539,5541,5542,12975,12978,5527,5530,12980,12974,12970,12977,5540,12976,5528,12972],"class_list":["post-14231","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-imolopesim","tag-benefits-of-loperamide-hydrochloride","tag-benefits-opf-dimethicone","tag-dimethicone","tag-dimethicone-side-effects","tag-dimethicone-tablet","tag-imolopesim","tag-imolopesim-tablet","tag-loperamide-hydrochloride","tag-loperamide-hydrochloride-tablet","tag-side-effects-of-imolopesim","tag-side-effects-of-loperamide-hydrochloride","tag-what-dimethicone-is-used-for","tag-what-imolopesim-is-used-for","tag-what-is-dimethicone","tag-what-is-imolopesim","tag-what-is-loperamide-hydrochloride","tag-what-loperamide-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14231","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14231"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14231\/revisions"}],"predecessor-version":[{"id":14987,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14231\/revisions\/14987"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14231"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14231"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14231"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}