{"id":14152,"date":"2021-09-25T07:17:57","date_gmt":"2021-09-25T07:17:57","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14152"},"modified":"2021-10-21T07:50:37","modified_gmt":"2021-10-21T07:50:37","slug":"imatinib-mylan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/imatinib-mylan\/","title":{"rendered":"Imatinib Mylan &#8211; Imatinib uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg&nbsp;film-coated tablets<br>imatinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Imatinib Mylan is and what it is used for<\/h2>\n\n\n\n<p>Imantinib Mylan is a medicine that contains an active substance called imatinib.&nbsp;The drug acts by&nbsp;inhibiting the&nbsp;growth of abnormal cells in the diseases listed below.&nbsp;These include certain types of cancer.<\/p>\n\n\n\n<p><strong>Imatinib Mylan is a treatment for adults and children for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Chronic myeloid leukemia&nbsp;(CML).&nbsp;<\/strong>&nbsp;&nbsp;Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;usually help the body fight&nbsp;infection&nbsp;.&nbsp;Chronic myeloid leukemia&nbsp;is a form of&nbsp;leukemia in&nbsp;which certain abnormal&nbsp;white blood cells&nbsp;(so-called myeloid cells) begin to grow out of control.<\/li><li><strong>Philadelphia chromosome-positive&nbsp;acute lymphoblastic leukemia&nbsp;(&nbsp;Ph-&nbsp;positive ALL).&nbsp;<\/strong>Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;normally help the body fight&nbsp;infection&nbsp;.&nbsp;Acute lymphoblastic leukemia&nbsp;is a form of&nbsp;leukemia&nbsp;in which certain abnormal, immature&nbsp;white blood cells&nbsp;(so-called&nbsp;lymphoblasts&nbsp;) begin to grow out of control.&nbsp;Imatinib Mylan inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p><strong>Imatinib Mylan is also a treatment for adults for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Myelodysplastic \/ myeloproliferative disorders (MDS \/ MPD).&nbsp;<\/strong>These are a group of blood diseases in which certain blood cells begin to grow out of control.&nbsp;Imatinib Mylan inhibits the growth of these cells in a certain subset of these diseases.&nbsp;<\/li><li><strong>Hypereosinophilic syndrome (HES) and \/ or&nbsp;chronic&nbsp;eosinophilic&nbsp;leukemia&nbsp;(CEL).&nbsp;<\/strong>These are blood diseases in which certain blood cells (so-called&nbsp;eosinophils&nbsp;) begin to grow out of control.&nbsp;Imatinib Mylan inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Dermatofibrosarcoma protuberans (DFSP).&nbsp;<\/strong>DFSP is a cancer of the&nbsp;tissue&nbsp;under the skin in which certain cells begin to grow out of control.&nbsp;Imatinib Mylan inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p>In the rest of this leaflet, abbreviations will be used when talking about these diseases.<\/p>\n\n\n\n<p>Ask your doctor if you have any questions about how Imatinib Mylan works or why this medicine has been prescribed for you.<\/p>\n\n\n\n<p>Imantinib contained in Imantinib Mylan may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Imatinib Mylan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Imatinib Mylan<\/h2>\n\n\n\n<p>Imatinib Mylan will only be prescribed to you by a doctor with medical experience in treating different types of blood cancers or solid&nbsp;tumors.&nbsp;<\/p>\n\n\n\n<p>Follow all of your doctor&#8217;s instructions carefully, although these may differ from the general information in this leaflet.<\/p>\n\n\n\n<p><strong>Do not take Imatinib Mylan<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to imatinib or any of the other ingredients of this medicine (listed in section 6).If this applies to you,&nbsp;<strong>do not take Imatinib Mylan without telling your doctor<\/strong>&nbsp;.<\/li><\/ul>\n\n\n\n<p>If you think you may be allergic but are not sure, ask your doctor for further advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Imatinib Mylan.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had a liver, kidney or heart disease.<\/li><li>if you are taking the medicine levothyroxine because your&nbsp;thyroid&nbsp;has been removed.<\/li><li>if you have ever had or may now have a&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;.&nbsp;The reason for this is that Imatinib Mylan can cause your&nbsp;hepatitis&nbsp;B to become active again, which in some cases can be fatal.&nbsp;Patients will be closely monitored by their physician for signs of this&nbsp;infection&nbsp;before starting treatment.<\/li><li>if you get bruises, bleeding, fever, get very tired and confused when taking imatinib, contact your doctor.&nbsp;This may be a sign of an injury to the blood vessels called thrombotic microangiopathy (TMA).<\/li><\/ul>\n\n\n\n<p>If any of these apply to you,&nbsp;<strong>tell your doctor before taking Imatinib Mylan.<\/strong><\/p>\n\n\n\n<p>You may become more sensitive to the sun while taking Imatinib Mylan.&nbsp;It is important to cover exposed areas of the skin and use sunscreen with a high sun protection factor (SPF).&nbsp;These precautions also apply to children.<\/p>\n\n\n\n<p><strong>When taking Imatinib Mylan, tell your doctor immediately<\/strong>&nbsp;if you gain weight quickly.&nbsp;Imatinib Mylan may cause your body to bind fluid (severe&nbsp;fluid retention&nbsp;).<\/p>\n\n\n\n<p>When you take Imatinib Mylan, your doctor will regularly check that the medicine is working.&nbsp;You will also be given blood samples and weighed regularly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Imatinib Mylan is also a treatment for children with CML.&nbsp;There is no experience from children with CML under 2 years.&nbsp;There is limited experience from children with&nbsp;Ph-positive ALL and very limited experience from children with MDS \/ MPD, DFSP, and HES \/ CEL.<\/p>\n\n\n\n<p>Some children and adolescents taking Imatinib Mylan may grow more slowly than usual.&nbsp;Your doctor will regularly check your growth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Imatinib Mylan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription (eg&nbsp;paracetamol&nbsp;) and herbal medicines (eg&nbsp;St. John&#8217;s wort&nbsp;).&nbsp;Some medicines may affect the effect of Imatinib Mylan when taken together.&nbsp;They may increase or decrease the effect of Imatinib Mylan and either leads to more&nbsp;side effects&nbsp;or make Imatinib Mylan less effective.&nbsp;Imatinib Mylan can do the same for some other medicines.<\/p>\n\n\n\n<p>Tell your doctor if you are taking medicines that prevent the formation of blood clots.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<\/li><li>Imatinib Mylan is not recommended during pregnancy unless clearly necessary as it may harm your baby.&nbsp;Your doctor will discuss the possible risks of taking Imatinib Mylan during pregnancy.<\/li><li>Women who may become pregnant are advised to use effective contraception during treatment.<\/li><li>Do not breast-feed during treatment with Imatinib Mylan.<\/li><li>Patients who are concerned about their&nbsp;fertility&nbsp;when taking Imatinib Mylan are advised to consult their doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may feel dizzy or tired or have blurred vision when using this medicine.&nbsp;If this happens, do not drive or use any tools or machines until you feel well again.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Imatinib Mylan<\/h2>\n\n\n\n<p>Your doctor has prescribed Imatinib Mylan because you are suffering from a serious illness.&nbsp;Imatinib Mylan can help you fight this condition.<\/p>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;It is important that you do this as long as your doctor or pharmacist tells you to.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Do not stop taking Imatinib Mylan unless your doctor tells you to.&nbsp;If you can not take the medicine according to your doctor&#8217;s&nbsp;prescription&nbsp;or if you feel that you do not need it anymore, contact your doctor immediately.<\/p>\n\n\n\n<p><strong>How much Imatinib Mylan to take?<\/strong><\/p>\n\n\n\n<p><strong>Use for adults<\/strong><\/p>\n\n\n\n<p>Your doctor will tell you exactly how many Imatinib Mylan tablets to take.<\/p>\n\n\n\n<p><strong>If you are being treated for KML:<\/strong><\/p>\n\n\n\n<p>Depending on your condition, the usual starting dose is either 400 mg or 600 mg:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>400 mg taken as 4 tablets&nbsp;<strong>once<\/strong>&nbsp;a day,<\/li><li>600 mg taken as 6 tablets&nbsp;<strong>once<\/strong>&nbsp;a day.<\/li><\/ul>\n\n\n\n<p>Your doctor may prescribe a higher or lower&nbsp;dose&nbsp;depending on how you respond to the treatment.&nbsp;If your daily&nbsp;dose&nbsp;is 800 mg (8 tablets), you should take 4 tablets in the morning and 4 tablets in the evening.<\/p>\n\n\n\n<p><strong>&#8211; If you are being treated for&nbsp;Ph-positive<\/strong> ALL: The<br>the starting dose is 600 mg taken as 6 tablets&nbsp;<strong>once a day.<\/strong><\/p>\n\n\n\n<p><strong>&#8211; If you are being treated for MDS \/ MPD: The<br><\/strong>the starting dose is 400 mg taken as 4 tablets&nbsp;<strong>once a day.<\/strong><\/p>\n\n\n\n<p><strong>&#8211; If you are being treated for HES \/ CEL: The<br><\/strong>starting dose is 100 mg taken as a tablet once a day.&nbsp;Your doctor may decide to increase the&nbsp;dose to&nbsp;one to 400 mg taken as 4 tablets&nbsp;<strong>once<\/strong>&nbsp;a day<strong>,<\/strong>&nbsp;depending on how you respond to the treatment.<\/p>\n\n\n\n<p><strong>&#8211; If you are being treated for DFSP:<br><\/strong>Dose&nbsp;one is 800 mg per day (8 tablets) taken as 4 tablets in the morning and 4 tablets in the evening.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Your doctor will tell you how many Imatinib Mylan tablets to give to your child.&nbsp;The amount of Imatinib Mylan given depends on your baby&#8217;s condition, body weight, and height.&nbsp;The total&nbsp;dose&nbsp;for children should not exceed 800 mg for CML and 600 mg for&nbsp;Ph-positive ALL.&nbsp;The treatment can either be given to your child as a single dose or alternatively the daily&nbsp;dose can&nbsp;be given on two different occasions (half in the morning and a half in the evening).<\/p>\n\n\n\n<p><strong>When and how to take Imatinib Mylan<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Take Imatinib Mylan with a meal.&nbsp;<\/strong>It helps to protect against stomach problems when you take Imatinib Mylan.<\/li><li><strong>Swallow the tablets whole with a large glass of water.<\/strong><\/li><\/ul>\n\n\n\n<p>If you can not swallow the tablets, you can slurry them in a glass of non-carbonated water or apple juice.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take about 50 ml for each 100 mg tablet.<\/li><li>Stir with a spoon until the tablets have completely dissolved.<\/li><li>Once the tablet has dissolved, immediately drink the entire contents of the glass.&nbsp;Residues of the dissolved tablets may remain in the glass.<\/li><\/ul>\n\n\n\n<p><strong>How long to take Imatinib Mylan?<\/strong><\/p>\n\n\n\n<p>Continue to take Imatinib Mylan every day for as long as your doctor tells you to.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Imatinib Mylan than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested&nbsp;<strong>the<\/strong>&nbsp;medicine,&nbsp;contact&nbsp;<strong>a<\/strong>&nbsp;doctor, hospital, or the Poison Information Center i<strong>mmediately<\/strong>&nbsp;for risk assessment and advice.&nbsp;You may need medical attention.&nbsp;Take the medicine pack with you.&nbsp;Symptoms of an overdose include nausea, vomiting, diarrhea, rash, redness of the skin, fatigue, uncontrollable movements, muscle aches, abdominal pain, headache, decreased appetite, weakness and high body temperature.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Imatinib Mylan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, take it as soon as you remember.&nbsp;However, skip the missed&nbsp;dose&nbsp;if it is soon time to take the next&nbsp;dose&nbsp;.<\/li><li>Then continue with your normal schedule.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects&nbsp;, although not everybody gets them.&nbsp;They are usually of mild to moderate severity.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Tell your doctor immediately if you get any of the following:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Changes in the number of&nbsp;blood cells&nbsp;that can cause signs of&nbsp;infection&nbsp;such as fever, chills, sore throat or sore mouth (changes in the number of&nbsp;white blood cells&nbsp;), pale skin, tiredness and shortness of breath and dark urine (low number of&nbsp;red blood cells&nbsp;), bleeding and bruising which lasts longer than normal or occurs for no known reason, when you have not injured yourself (changes in the number of&nbsp;platelets&nbsp;).<\/li><li>Rapid weight gain.&nbsp;Imatinib Mylan can cause your body to bind water (severe&nbsp;fluid retention&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever with chills, rapid heartbeat, rapid breathing and \/ or confusion (signs of sepsis, severe reaction to an&nbsp;infection&nbsp;)<\/li><li>Chest pain (which may radiate to the arms), irregular heartbeat, shortness of breath, swelling in the feet or ankles due to accumulation of fluid (signs of heart problems).<\/li><li>Cough, difficulty breathing or painful breathing (signs of lung problems).<\/li><li>Nausea, with decreased appetite, dark urine, yellowing of the skin or eyes (signs of liver problems).<\/li><li>Skin rash,&nbsp;redness&nbsp;with blisters on lips, eyes, skin or mouth, flaking of the skin, fever, raised red or purple skin areas,&nbsp;itching&nbsp;, burning sensation, rash with small blisters (signs of skin problems).<\/li><li>Severe abdominal pain, vomiting or stool blood, black stools (signs of gastrointestinal disease).<\/li><li>Severe decreased urine output, thirst, dehydration, nausea, loss of appetite, weakness, fatigue, headache, general malaise (signs of kidney disease).<\/li><li>Severe headache, weakness or paralysis of the legs or face, difficulty speaking, sudden unconsciousness (signs of nervous system problems such as bleeding or swelling of the skull \/ brain).<\/li><li>Eye pain or impaired vision.&nbsp;Bleeding in the eyes.<\/li><li>Sudden swelling and&nbsp;redness&nbsp;of the skin (signs of a skin infection called&nbsp;cellulite&nbsp;).<\/li><li>Impaired hearing.<\/li><li>Muscle weakness and muscle cramps with abnormal heart rhythm (signs that indicate changes in the amount of&nbsp;potassium&nbsp;in your blood).<\/li><li>Severe pain in the upper abdomen, often with nausea and vomiting<\/li><li>Nausea, shortness of breath, irregular heartbeat, cloudy urine, fatigue and \/ or joint problems associated with abnormal laboratory values \u200b\u200b(eg high&nbsp;potassium&nbsp;,&nbsp;uric acid&nbsp;and calcium levels in the blood and low phosphorus levels in the blood).<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle cramps, with fever, red-brown urine, pain or weakness in your muscles (signs of muscle problems)<\/li><li>Nausea with diarrhea and vomiting, persistent constipation, abdominal pain or fever (signs of intestinal problems)<\/li><li>Pelvic pain sometimes with nausea and vomiting, with unexpected vaginal bleeding, dizziness or fainting due to low&nbsp;blood pressure&nbsp;(signs of ovarian or uterine problems).<\/li><li>Blood clots in small blood vessels (thrombotic microangiopathy).<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in unknown number of users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain in the hips or difficulty walking<\/li><li>Slow growth in children and adolescents&nbsp;<\/li><li>Chronic&nbsp;renal failure<\/li><li>Severe&nbsp;allergic reaction&nbsp;with rash,&nbsp;itching&nbsp;or&nbsp;hives&nbsp;, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or difficulty breathing.<\/li><li>Sudden severe headache, loss of vision, loss of coordination, slurred speech, shortness of breath, chest pain, numbness, heat or swelling in the arms or legs (signs of a blockage in a blood vessel caused by a blood clot).<\/li><li>Allergic reaction&nbsp;that may affect the skin or other parts of the body such as the liver or&nbsp;blood cells&nbsp;(DRESS syndrome).&nbsp;Symptoms include rash, fever, enlarged&nbsp;lymph nodes&nbsp;for a long time, yellow skin or yellow whites of the eyes, unusual bruising or bleeding, unexplained muscle aches, frequent&nbsp;infections&nbsp;.<\/li><li>Recurrence (reactivation) of&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;when you have previously had&nbsp;hepatitis&nbsp;B (a liver infection).<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor immediately<\/strong>&nbsp;if you get any of the above.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;may include:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache or fatigue.<\/li><li>Nausea, vomiting, diarrhea or indigestion.<\/li><li>Rash.<\/li><li>Muscle cramps or pain in joints, muscles or bones during treatment with Imatinib Mylan or after stopping Imatinib Mylan.<\/li><li>Swelling around joints or swollen eyes.<\/li><li>Weight gain.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite, weight loss or taste disorders.<\/li><li>Dizziness or weakness.<\/li><li>Sleep problems (&nbsp;insomnia&nbsp;).<\/li><li>Runny eyes with&nbsp;itching&nbsp;,&nbsp;redness&nbsp;and swelling (conjunctivitis), watery eyes or blurred vision.<\/li><li>Nosebleed.<\/li><li>Abdominal pain or distended abdomen, flatulence, heartburn, constipation.<\/li><li>Itching&nbsp;.<\/li><li>Unexpectedly heavy hair loss or thinning of the hair.<\/li><li>Numbness or tingling in the hands and feet.<\/li><li>Joint pain with swelling.<\/li><li>Dry&nbsp;mouth&nbsp;, dry skin or dry eyes.<\/li><li>Decreased or increased sensitivity of the skin.<\/li><li>Increased photosensitivity in the skin.<\/li><li>Hot flashes, chills or night sweats.<\/li><li>Increased levels of liver enzymes detected in blood tests.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Depression, anxiety.<\/li><li>Memory problem.<\/li><li>General malaise.<\/li><li>High&nbsp;blood pressure&nbsp;.<\/li><li>Feeling dizzy, dizzy or fainting (signs of low&nbsp;blood pressure&nbsp;).<\/li><li>Somnolence.<\/li><li>Restless legs,&nbsp;tremors&nbsp;.<\/li><li>Pain in the lower back, which radiates to the leg (sciatica).<\/li><li>Scams (&nbsp;vertigo&nbsp;).<\/li><li>Ringing in the ears.<\/li><li>Increased sweating.<\/li><li>Increased appetite.<\/li><li>Cracked fingernails or toenails.<\/li><li>Discoloration of the skin.<\/li><li>Skin rash, often with pain and blisters (&nbsp;shingles&nbsp;).<\/li><li>Numb or cold toes and fingers (signs of Raynaud&#8217;s syndrome).<\/li><li>Pain, discomfort when swallowing or difficulty swallowing.<\/li><li>Sore mouth, dry or chapped lips, sores in the mouth.<\/li><li>Cold sores.<\/li><li>Belching.<\/li><li>Stiff joints or muscles.<\/li><li>Frequent urination, pain when urinating, cloudy urine or blood in the urine.<\/li><li>Abundant or irregular menstruation.<\/li><li>Enlarged breasts (even in men), pain in the nipple.<\/li><li>Swollen&nbsp;lymph nodes&nbsp;in the neck, armpits or groin<\/li><li>Swelling of the scrotum.<\/li><li>Sexual problems, including difficulty maintaining or achieving an&nbsp;erection&nbsp;in men and decreased sexual desire.<\/li><li>Changes in the levels of certain chemicals in the blood that show how the body works and that are detected in blood tests.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Confusion.<\/li><li>Cramps.<\/li><li>Color changes on nails.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Redness&nbsp;and \/ or swelling in the palms and soles of the feet which may be accompanied by a stinging sensation or burning pain.<\/li><li>Painful changes in the skin with or without blisters.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Imatinib Mylan<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is imatinib mesylate.&nbsp;Each tablet contains imatinib mesylate equivalent to 100 mg imatinib.<\/li><li>The other ingredients are microcrystalline cellulose (E460), low-substituted hydroxypropylcellulose (E463), povidone (E1201), crospovidone (Type A) (E1202), anhydrous&nbsp;colloidal&nbsp;silica, magnesium stearate (E572)<\/li><li>The film coating contains hypromellose (E464), macrogol 400, talc (E553b), red iron oxide (E172), yellow iron oxide (E172)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Imatinib Mylan 100 mg is a dark yellow to brownish orange, round film-coated tablet with a score line on one side and the label \u201c100\u201d on the other side.&nbsp;The tablet can be divided into two equal&nbsp;doses&nbsp;.<\/p>\n\n\n\n<p>The packs contain 20, 60, 60&#215;1, 120 or 180 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Mylan AB<\/p>\n\n\n\n<p>Box 23033<\/p>\n\n\n\n<p>104 35 Stockholm<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Remedica Ltd<\/p>\n\n\n\n<p>Acharnon Street, Limassol Industrial Estate<\/p>\n\n\n\n<p>3056 Limassol<\/p>\n\n\n\n<p>Cyprus<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imantinib Mylan is a medicine that contains an active substance called imatinib. The drug acts by inhibiting the growth of abnormal cells in the diseases listed below. These include certain types of cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[13132,13151,13120,13146,13149,13125,13123,13150,13122,13148,13121,13147],"class_list":["post-14152","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-imatinib","tag-benefits-of-imatinib-mylan","tag-imatinib","tag-imatinib-mylan","tag-imatinib-mylan-tablet","tag-imatinib-side-effects","tag-imatinib-tablet","tag-side-effects-of-imatinib-mylan","tag-what-imatinib-is-used-for","tag-what-imatinib-mylan-is-used-for","tag-what-is-imatinib","tag-what-is-imatinib-mylan"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14152"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14152\/revisions"}],"predecessor-version":[{"id":15046,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14152\/revisions\/15046"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}