{"id":14150,"date":"2021-09-25T07:16:30","date_gmt":"2021-09-25T07:16:30","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14150"},"modified":"2021-10-21T07:50:42","modified_gmt":"2021-10-21T07:50:42","slug":"imatinib-krka-dd","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/imatinib-krka-dd\/","title":{"rendered":"Imatinib Krka dd &#8211; imatinib uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg&nbsp;film-coated tablets<br>imatinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Imatinib Krka dd is and what it is used for<\/h2>\n\n\n\n<p>Imatinib Krka dd is a medicine that contains an active substance called imatinib.&nbsp;The drug acts by&nbsp;inhibiting the&nbsp;growth of abnormal cells in the diseases listed below.&nbsp;These include certain types of cancer.<\/p>\n\n\n\n<p><strong>Imatinib Krka dd is a treatment for adults and children for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Chronic myeloid leukemia&nbsp;(CML)<\/strong>&nbsp;.&nbsp;Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;usually help the body fight&nbsp;infection&nbsp;.&nbsp;Chronic myeloid leukemia&nbsp;is a form of&nbsp;leukemia in&nbsp;which certain abnormal&nbsp;white blood cells&nbsp;(so-called myeloid cells) begin to grow out of control.<\/li><li><strong>Philadelphia chromosome-positive&nbsp;acute lymphoblastic leukemia&nbsp;(&nbsp;Ph-&nbsp;positive ALL)<\/strong>&nbsp;.&nbsp;Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;normally help the body fight&nbsp;infection&nbsp;.&nbsp;Acute lymphoblastic leukemia&nbsp;is a form of&nbsp;leukemia&nbsp;in which certain abnormal, immature&nbsp;white blood cells&nbsp;(so-called&nbsp;lymphoblasts&nbsp;) begin to grow out of control.&nbsp;Imatinib Krka dd inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p><strong>Imatinib Krka dd is also a treatment for adults for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Myelodysplastic \/ myeloproliferative disorders (MDS \/ MPD)<\/strong>&nbsp;.&nbsp;These are a group of blood diseases in which certain blood cells begin to grow out of control.&nbsp;Imatinib Krka dd inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Hypereosinophilic syndrome (HES) and \/ or&nbsp;chronic&nbsp;eosinophilic&nbsp;leukemia&nbsp;(CEL)<\/strong>&nbsp;.&nbsp;These are blood diseases in which certain blood cells (so-called&nbsp;eosinophils&nbsp;) begin to grow out of control.&nbsp;Imatinib Krka dd inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Dermatofibrosarcoma protuberance (DFSP)<\/strong>&nbsp;.&nbsp;DFSP is a cancer of the&nbsp;tissue&nbsp;under the skin in which certain cells begin to grow out of control.&nbsp;Imatinib Krka dd inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p>In the rest of this leaflet, abbreviations will be used when talking about these diseases.<\/p>\n\n\n\n<p>Ask your doctor if you have any questions about how this medicine works or why this medicine has been prescribed for you.<\/p>\n\n\n\n<p>Imatinib contained in Imatinib Krka dd may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Imatinib Krka dd<\/h2>\n\n\n\n<p>Imatinib Krka dd will only be prescribed to you by a doctor with medical experience in treating different types of blood cancers or solid&nbsp;tumors.<\/p>\n\n\n\n<p>Follow all of your doctor&#8217;s instructions carefully, although these may differ from the general information in this leaflet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Imatinib Krka dd<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to imatinib or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p><strong>If this applies to you,&nbsp;do not take Imatinib Krka dd but tell your doctor<\/strong>.<\/p>\n\n\n\n<p>If you think you may be allergic but are not sure, ask your doctor for further advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Imatinib Krka dd:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had a liver, kidney or heart disease<\/li><li>if you are taking the medicine levothyroxine due to&nbsp;that your&nbsp;thyroid gland&nbsp;has been removed<\/li><li>if you have ever had or may now have a&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;.&nbsp;The reason for this is that Imatinib Krka dd can cause your&nbsp;hepatitis&nbsp;B to become active again, which in some cases can be fatal.&nbsp;Patients will be closely monitored by their physician for signs of this&nbsp;infection&nbsp;before starting treatment.<\/li><li>if you get bruises, bleeding, fever, get very tired and confused when taking Imatinib Krka dd, contact your doctor.&nbsp;This may be a sign of an injury to the blood vessels called thrombotic microangiopathy (TMA).<\/li><\/ul>\n\n\n\n<p>If any of these apply to you<strong>,&nbsp;tell your doctor before taking Imatinib Krka dd<\/strong><\/p>\n\n\n\n<p>You may become more sensitive to the sun while taking Imatinib Krka dd It is important to cover exposed areas of the skin and use sunscreen with a high sun protection factor (SPF).&nbsp;These precautions also apply to children.<\/p>\n\n\n\n<p><strong>When taking Imatinib Krka dd, tell your doctor immediately<\/strong>&nbsp;if you gain weight quickly.&nbsp;Imatinib Krka dd may cause your body to bind fluid (severe&nbsp;fluid retention&nbsp;).<\/p>\n\n\n\n<p>When you take Imatinib Krka dd, your doctor will regularly check that the medicine is working.&nbsp;You will also be given blood samples and weighed regularly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Imatinib Krka dd is also a treatment for children with CML.&nbsp;There is no experience from children with CML under 2 years.&nbsp;There is limited experience from children with&nbsp;Ph-positive ALL and very limited experience from children with MDS \/ MPD, DFSP, and HES \/ CEL.<\/p>\n\n\n\n<p>Some children and adolescents taking Imatinib Krka dd may grow more slowly than usual.&nbsp;The doctor will regularly check the growth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Imatinib Krka dd<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription (eg&nbsp;paracetamol&nbsp;) and herbal medicines (eg&nbsp;St. John&#8217;s wort&nbsp;).&nbsp;Some medicines may affect the effect of Imatinib Krka dd when taken together.&nbsp;They may increase or decrease the effect of Imatinib Krka dd and either leads to more&nbsp;side effects&nbsp;or make Imatinib Krka dd less effective.&nbsp;Imatinib Krka dd may do the same against certain other medicines.<\/p>\n\n\n\n<p>Tell your doctor if you are taking medicines that prevent the formation of blood clots.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Imatinib Krka dd is not recommended during pregnancy unless it is necessary as it may harm your baby.&nbsp;Your doctor will discuss the possible risks of taking Imatinib Krka dd during pregnancy.<\/li><li>Women who may become pregnant are advised to use effective contraception during treatment.<\/li><li>Do not breast-feed during treatment with Imatinib Krka dd<\/li><li>Patients who are concerned about their&nbsp;fertility&nbsp;when taking Imatinib Krka dd are advised to consult their doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may feel dizzy or tired or have blurred vision when using this medicine.&nbsp;If this happens, do not drive or use any tools or machines until you feel well again.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Imatinib Krka dd contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Imatinib Krka dd<\/h2>\n\n\n\n<p>Your doctor has prescribed Imatinib Krka dd because you are suffering from a serious illness.&nbsp;Imatinib Krka dd can help you fight this condition.<\/p>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;You must do this as long as your doctor or pharmacist tells you to.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Do not stop taking Imatinib Krka dd unless your doctor tells you to.&nbsp;If you can not take the medicine according to your doctor&#8217;s&nbsp;prescription&nbsp;or if you feel that you do not need it anymore, contact your doctor immediately.<\/p>\n\n\n\n<p><strong>How much Imatinib Krka dd to take?<\/strong><\/p>\n\n\n\n<p><strong>Use for adults<\/strong><\/p>\n\n\n\n<p>Your doctor will tell you exactly how many Imatinib Krka dd tablets to take.<\/p>\n\n\n\n<p><strong><em>If you are being treated for KML:<\/em><\/strong><\/p>\n\n\n\n<p>Depending on your condition, the usual starting dose is either 400 mg or 600 mg:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>400 mg<\/strong>&nbsp;to be taken as 4 tablets&nbsp;<strong>a<\/strong>&nbsp;once a day,<\/li><li><strong>600 mg<\/strong>&nbsp;taken as 6 tablets&nbsp;<strong>a<\/strong>&nbsp;once a day.<\/li><\/ul>\n\n\n\n<p>For CML, your doctor may prescribe a higher or lower&nbsp;dose&nbsp;depending on how you respond to treatment.&nbsp;If your daily&nbsp;dose&nbsp;is 800 mg (8 tablets), you should take 4 tablets in the morning and 4 tablets in the evening.<\/p>\n\n\n\n<p><em><strong>If you are being treated for&nbsp;Ph-positive ALL:<\/strong><\/em><\/p>\n\n\n\n<p>The starting dose is 600 mg taken as 6 tablets&nbsp;<strong>once<\/strong>&nbsp;a day.<\/p>\n\n\n\n<p><em><strong>If you are being treated for MDS \/ MPD:<\/strong><\/em><\/p>\n\n\n\n<p>The starting dose is 400 mg taken as 4 tablets&nbsp;<strong>once<\/strong>&nbsp;daily.<\/p>\n\n\n\n<p><em><strong>If you are being treated for HES \/ CEL:<\/strong><\/em><\/p>\n\n\n\n<p>The starting dose is 100 mg taken as a tablet&nbsp;<strong>once<\/strong>&nbsp;a day.<\/p>\n\n\n\n<p>Your doctor may decide to increase the&nbsp;dose from&nbsp;one to 400 mg, which is taken as 4 tablets&nbsp;<strong>once<\/strong>&nbsp;a day, depending on how you respond to the treatment.<\/p>\n\n\n\n<p><em><strong>If you are being treated for DFSP:<\/strong><\/em><\/p>\n\n\n\n<p>Dose&nbsp;one is 800 mg per day (8 tablets) taken as 4 tablets in the morning and 4 tablets in the evening.<\/p>\n\n\n\n<p><strong>When and how to take Imatinib Krka dd?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take Imatinib Krka dd with a meal.&nbsp;It helps to protect against stomach problems when you take Imatinib Krka dd<\/li><li>Swallow the tablets whole with a large glass of water.<\/li><\/ul>\n\n\n\n<p>If you can not swallow the tablets, you can slurry them in a glass of non-carbonated water or apple juice:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take about 50 ml for each 100 mg tablet.<\/li><li>Stir with a spoon until the tablets have completely dissolved.<\/li><li>Once the tablet has dissolved, immediately drink the entire contents of the glass.&nbsp;Residues of the dissolved tablets may remain in the glass.<\/li><\/ul>\n\n\n\n<p><strong>How long to take Imatinib Krka dd?<\/strong><\/p>\n\n\n\n<p>Continue to take Imatinib Krka dd every day for as long as your doctor tells you to.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Your doctor will tell you how many Imatinib Krka dd tablets to give to your child.&nbsp;The amount of Imatinib Krka dd given depends on your child&#8217;s condition, body weight, and height.&nbsp;The total&nbsp;dose&nbsp;for children should not exceed 800 mg for CML and 600 mg for&nbsp;Ph-positive ALL.&nbsp;The treatment can either be given to your child as a single dose or the daily&nbsp;dose can&nbsp;be given on two different occasions (half in the morning and a half in the evening).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Imatinib Krka dd than you should &nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has accidentally ingested the medicine, contact a doctor, hospital, pharmacy staff, or the Poison Information Center immediately for assessment of the risk and advice.&nbsp;You may need medical attention.&nbsp;Take the medicine pack with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Imatinib Krka dd<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, take it as soon as you remember.&nbsp;However, skip the missed&nbsp;dose&nbsp;if it is soon time to take the next&nbsp;dose&nbsp;.<\/li><li>Then continue with your normal schedule.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;They are usually of mild to moderate severity.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Tell your doctor immediately if you get any of the following:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10)&nbsp;<strong>or common<\/strong>&nbsp;(may affect up to 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Rapid weight gain.&nbsp;Imatinib Krka dd may cause your body to bind water (severe&nbsp;fluid retention&nbsp;).<\/li><li>Signs of&nbsp;infection&nbsp;, e.g.&nbsp;fever, frostbite, sore throat or sore mouth.&nbsp;Imatinib Krka dd may lead to a reduction in the number of&nbsp;white blood cells&nbsp;so that you can get&nbsp;infection&nbsp;more easily&nbsp;.<\/li><li>Sudden bleeding or sores (when you have not injured yourself).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 users)&nbsp;<strong>or rare<\/strong>&nbsp;(may affect up to 1 in 1,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest pain, irregular heartbeat (signs of heart problems).<\/li><li>Cough, difficulty breathing or painful breathing (signs of lung problems).<\/li><li>Feeling dizzy, dizzy or fainting (signs of low&nbsp;blood pressure&nbsp;).<\/li><li>Nausea, with decreased appetite, dark urine, yellowing of the skin or eyes (signs of liver problems).<\/li><li>Skin rash,&nbsp;redness&nbsp;with blisters on lips, eyes, skin or mouth, flaking of the skin, fever, raised red or purple skin areas,&nbsp;itching&nbsp;, burning sensation, rash with small blisters (signs of skin problems).<\/li><li>Severe abdominal pain, blood in vomit, stool or urine, black stools (signs of gastrointestinal disease).<\/li><li>Severe decreased urine output, thirst (signs of kidney problems).<\/li><li>Nausea, with diarrhea and vomiting, abdominal pain or fever (signs of intestinal problems).<\/li><li>Severe headache, weakness or paralysis of the legs or face, difficulty speaking, sudden unconsciousness (signs of nervous system problems such as bleeding or swelling of the skull \/ brain).<\/li><li>Paleness, fatigue and shortness of breath with dark urine (signs of low level of&nbsp;red blood cells&nbsp;).<\/li><li>Eye pain or impaired vision, bleeding in the eyes.<\/li><li>Pain in the hips or difficulty walking.<\/li><li>Numb or cold toes and fingers (signs of Raynaud&#8217;s syndrome).<\/li><li>Sudden swelling and&nbsp;redness&nbsp;of the skin (signs of a skin infection called&nbsp;cellulite&nbsp;).<\/li><li>Impaired hearing.<\/li><li>Muscle weakness and muscle cramps with abnormal heart rhythm (signs that indicate changes in the amount of&nbsp;potassium&nbsp;in your blood).<\/li><li>Tendency to get bruises.<\/li><li>Stomach pain, with nausea.<\/li><li>Muscle cramps, with fever, red-brown urine, pain or weakness in your muscles (signs of muscle problems).<\/li><li>Pelvic pain sometimes with nausea and vomiting, with unexpected vaginal bleeding, dizziness or fainting due to low&nbsp;blood pressure&nbsp;(signs of ovarian or uterine problems).<\/li><li>Nausea, shortness of breath, irregular heartbeat, cloudy urine, fatigue and \/ or joint problems associated with abnormal laboratory values \u200b\u200b(eg high&nbsp;potassium&nbsp;,&nbsp;uric acid&nbsp;and calcium levels, as well as low phosphorus levels in the blood).<\/li><li>Blood clots in small blood vessels (thrombotic microangiopathy).<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Combination of severe skin rash, nausea, fever, high levels of certain&nbsp;white blood cells&nbsp;or yellow skin or eyes (signs of jaundice) with shortness of breath, chest pain \/ discomfort, greatly reduced urine production and feeling of thirst, etc. (signs of treatment-&nbsp;related allergic reaction&nbsp;).<\/li><li>Chronic&nbsp;renal failure<\/li><li>Recurrence (reactivation) of&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;when you have previously had&nbsp;hepatitis&nbsp;B (a liver infection).<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor immediately<\/strong>&nbsp;if you get any of the above.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;may include:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache or fatigue.<\/li><li>Nausea, vomiting, diarrhea or indigestion.<\/li><li>Rash.<\/li><li>Muscle cramps or pain in joints, muscles or bones during treatment with Imatinib Krka dd or after stopping Imatinib Krka dd<\/li><li>Swelling around joints or swollen eyes.<\/li><li>Weight gain.<\/li><li>Tell your doctor if any of these affect you seriously.<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite, weight loss or taste disorders.<\/li><li>Dizziness or weakness.<\/li><li>Sleep problems (&nbsp;insomnia&nbsp;).<\/li><li>Runny eyes with&nbsp;itching&nbsp;,&nbsp;redness&nbsp;and swelling (conjunctivitis), watery eyes or blurred vision.<\/li><li>Nosebleed.<\/li><li>Abdominal pain or distended abdomen, flatulence, heartburn, constipation.<\/li><li>Itching&nbsp;.<\/li><li>Unexpectedly heavy hair loss or thinning of the hair.<\/li><li>Numbness in hands and feet.<\/li><li>Sores in the mouth.<\/li><li>Joint pain with swelling.<\/li><li>Dry&nbsp;mouth&nbsp;, dry skin or dry eyes.<\/li><li>Decreased or increased sensitivity of the skin.<\/li><li>Hot flashes, chills or night sweats.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Redness&nbsp;and \/ or swelling in the palms and soles of the feet which may be accompanied by a stinging sensation or burning pain.<\/li><li>Painful changes in the skin with or without blisters.<\/li><li>Slow growth in children and adolescents.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if any of these affect you seriously.<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Imatinib Krka dd<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is imatinib.<\/p>\n\n\n\n<p>Each film-coated tablet contains 100 mg imatinib (as mesilate).<\/p>\n\n\n\n<p>The other ingredients (excipients) are&nbsp;lactose monohydrate,&nbsp;maize&nbsp;starch, hydroxypropyl cellulose, microcrystalline cellulose (E460), crospovidone,&nbsp;colloidal&nbsp;anhydrous silica and magnesium stearate (E470b) in the tablet core, as well as poly (vinyl alcohol), titanium dioxide (E17) ) and yellow iron oxide (E172) in the film coating.&nbsp;See section 2 &#8220;Imatinib Krka dd contains lactose&#8221;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>The film-coated tablets are orange-brown, round (diameter 11 mm), slightly biconvex with bevelled edges, and a notch on one side.&nbsp;The tablet can be divided into two equal&nbsp;doses.<\/p>\n\n\n\n<p>Imatinib Krka dd is supplied in blister packs of 20, 30, 60, 90, 120, or 180 film-coated tablets (tablets) in a carton.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p><em>Local representative<\/em><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p>TAD Pharma GmbH, Heinz-Lohmann-Stra\u00dfe 5, 27472 Cuxhaven, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imatinib Krka dd is a medicine that contains an active substance called imatinib. The drug acts by inhibiting the growth of abnormal cells in the diseases listed below. These include certain types of cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[13132,13156,13120,13152,13157,13155,13125,13123,13122,13154,13121,13153],"class_list":["post-14150","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-imatinib","tag-benefits-of-imatinib-krka-dd","tag-imatinib","tag-imatinib-krka-dd","tag-imatinib-krka-dd-side-effects","tag-imatinib-krka-dd-tablet","tag-imatinib-side-effects","tag-imatinib-tablet","tag-what-imatinib-is-used-for","tag-what-imatinib-krka-dd-is-used-for","tag-what-is-imatinib","tag-what-is-imatinib-krka-dd"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14150","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14150"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14150\/revisions"}],"predecessor-version":[{"id":15047,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14150\/revisions\/15047"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14150"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14150"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14150"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}