{"id":14148,"date":"2021-09-25T07:15:05","date_gmt":"2021-09-25T07:15:05","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14148"},"modified":"2021-10-21T07:50:48","modified_gmt":"2021-10-21T07:50:48","slug":"imatinib-grindeks","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/imatinib-grindeks\/","title":{"rendered":"Imatinib Grindeks &#8211; Imatinib uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg&nbsp;Hard capsules<br>Imatinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Imatinib Grindeks is and what it is used for<\/h2>\n\n\n\n<p>Imatinib Grindeks is a medicine that contains an active substance called imatinib.&nbsp;The drug acts by&nbsp;inhibiting the&nbsp;growth of abnormal cells in the diseases listed below.&nbsp;These include certain types of cancer.<\/p>\n\n\n\n<p><strong>Imatinib Grindeks is a treatment for adults and children with:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Chronic myeloid leukemia&nbsp;(CML).&nbsp;<\/strong>Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;usually help the body fight&nbsp;infection&nbsp;.&nbsp;Chronic myeloid leukemia&nbsp;is a form of&nbsp;leukemia in&nbsp;which certain abnormal&nbsp;white blood cells&nbsp;(so-called myeloid cells) begin to grow out of control.In adult patients, Imatinib Grindeks is used to treat a late stage of&nbsp;chronic&nbsp;myeloid&nbsp;leukemia&nbsp;called blast crisis.&nbsp;In children and adolescents, however, it can be used to treat all stages of the disease.<\/li><li><strong>Philadelphia chromosome-positive&nbsp;acute lymphoblastic leukemia&nbsp;(&nbsp;Ph-&nbsp;positive ALL).&nbsp;<\/strong>Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;normally help the body fight&nbsp;infection&nbsp;.&nbsp;Acute lymphoblastic leukemia&nbsp;is a form of&nbsp;leukemia&nbsp;in which certain abnormal, immature&nbsp;white blood cells&nbsp;(so-called&nbsp;lymphoblasts&nbsp;) begin to grow out of control.&nbsp;Imatinib Grindeks inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p><strong>Imatinib Grindeks&nbsp;<\/strong><strong>is also a treatment for adults for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Myelodysplastic \/ myeloproliferative disorders (MDS \/ MPD).&nbsp;<\/strong>These are a group of blood diseases in which certain blood cells begin to grow out of control.&nbsp;Imatinib Grindeks inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Hypereosinophilic syndrome (HES) and \/ or&nbsp;chronic&nbsp;eosinophilic&nbsp;leukemia&nbsp;(CEL).&nbsp;<\/strong>These are blood diseases in which certain blood cells (so-called&nbsp;eosinophils&nbsp;) begin to grow out of control.&nbsp;Imatinib Grindeks inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Dermatofibrosarcoma protuberans (DFSP).&nbsp;<\/strong>DFSP is a cancer of the&nbsp;tissue&nbsp;under the skin in which certain cells begin to grow out of control.&nbsp;Imatinib Grindeks inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p>In the rest of this leaflet, abbreviations will be used when talking about these diseases.<\/p>\n\n\n\n<p>Ask your doctor if you have any questions about how this medicine works or why this medicine has been prescribed for you.<\/p>\n\n\n\n<p>Imatinib contained in Imatinib Grindeks may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions and always follow their instructions<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Imatinib Grindeks<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Imatinib Grindeks<\/h2>\n\n\n\n<p>Imatinib Grindeks will only be prescribed to you by a doctor with medical experience in the treatment of blood cancer or solid&nbsp;tumors.<\/p>\n\n\n\n<p>Follow your doctor&#8217;s instructions carefully, even if they differ from the general information in this leaflet.<\/p>\n\n\n\n<p><strong>Do not take Imatinib Grindeks&nbsp;<\/strong><strong>:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to imatinib or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p>If this applies to you,&nbsp;<strong>do not take Imatinib Grindeks without telling your doctor.<\/strong><\/p>\n\n\n\n<p>If you think you may be allergic but are not sure, talk to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Imatinib Grindeks:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had a liver, kidney or heart disease.<\/li><li>if you are taking the medicine levothyroxine because your&nbsp;thyroid&nbsp;has been removed.<\/li><li>if you have ever had or may now have a&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;.&nbsp;The reason for this is that Imatinib Grindeks can cause your&nbsp;hepatitis&nbsp;B to become active again, which in some cases can be fatal.&nbsp;Patients will be closely monitored by their doctor for signs of this&nbsp;infection&nbsp;before starting treatment<\/li><li>if you get bruises, bleeding, fever, get very tired and confused when you take Imatinib Grindeks, contact your doctor.&nbsp;This may be a sign of an injury to the blood vessels called thrombotic microangiopathy (TMA).<\/li><\/ul>\n\n\n\n<p>If any of these apply to you,&nbsp;<strong>tell your doctor before taking Imatinib Grindeks.<\/strong><\/p>\n\n\n\n<p>You may become more sensitive to the sun while taking Imatinib Grindeks.&nbsp;It is important to cover exposed areas of the skin and use sunscreen with a high sun protection factor (SPF).&nbsp;These precautions also apply to children.<\/p>\n\n\n\n<p><strong>When taking Imatinib Grindeks, tell your doctor immediately<\/strong>&nbsp;if you are gaining weight fast.&nbsp;Imatinib Grindeks can cause your body to bind fluid (severe&nbsp;fluid retention&nbsp;).<\/p>\n\n\n\n<p>When you are taking Imatinib Grindeks, your doctor will regularly check that the medicine is working.&nbsp;You will also be given blood samples and weighed regularly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Imatinib Grindeks is also a treatment for children with CML.&nbsp;There is no experience from children with CML under 2 years.&nbsp;There is limited experience from children with&nbsp;Ph-positive ALL and very limited experience from children with MDS \/ MPD, DFSP, and HES \/ CEL.<\/p>\n\n\n\n<p>Some children and adolescents taking Imatinib Grindeks may grow more slowly than usual.&nbsp;The doctor will regularly check the growth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Imatinib Grindeks<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription (eg&nbsp;paracetamol&nbsp;) and herbal medicines (eg&nbsp;St. John&#8217;s wort&nbsp;).&nbsp;Some medicines may affect the effect of Imatinib Grindek when taken together.&nbsp;They may increase or decrease the effect of Imatinib Grindeks and either leads to more&nbsp;side effects&nbsp;or make Imatinib Grindeks less effective.&nbsp;Imatinib Grindeks can do the same for certain other medicines.<\/p>\n\n\n\n<p>Tell your doctor if you are taking medicines that prevent the formation of blood clots.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.<\/li><li>Imatinib Grindeks is not recommended during pregnancy unless it is necessary as it may harm your baby.&nbsp;Your doctor will discuss the possible risks of taking Imatinib Grindeks during pregnancy.<\/li><li>Women who may become pregnant are advised to use effective contraception during treatment.<\/li><li>Do not breast-feed during treatment with Imatinib Grindeks.<\/li><li>Patients who are concerned about their&nbsp;fertility&nbsp;when taking Imatinib Grindeks are advised to consult their doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may feel dizzy or tired or have blurred vision when using this medicine.&nbsp;If this happens, do not drive or use any tools or machines until you feel well again.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Imatinib Grindeks<\/h2>\n\n\n\n<p>Your doctor has prescribed Imatinib Grindeks because you are suffering from a serious illness.&nbsp;Imatinib Grindeks can help you fight this condition.<\/p>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;You must do this as long as your doctor or pharmacist tells you to.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Do not stop taking Imatinib Grindeks unless your doctor tells you to.&nbsp;If you can not take the medicine according to your doctor&#8217;s&nbsp;prescription&nbsp;or if you feel that you do not need it anymore, contact your doctor immediately.<\/p>\n\n\n\n<p><strong>How much Imatinib Grindeks to take?<\/strong><\/p>\n\n\n\n<p><strong>Use for adults<\/strong><\/p>\n\n\n\n<p>Your doctor will tell you exactly how many Imatinib Grindeks capsules to take.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you are being treated for KML:<\/strong>The usual dose is&nbsp;<strong>600 mg<\/strong>&nbsp;taken as 6 capsules&nbsp;<strong>a<\/strong>&nbsp;once daily.<\/li><\/ul>\n\n\n\n<p>For CML, your doctor may prescribe a higher or lower&nbsp;dose&nbsp;depending on how you respond to treatment.&nbsp;If your daily&nbsp;dose&nbsp;is 800 mg (8 capsules), take 4 capsules in the morning and 4 capsules in the evening.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you are being treated for&nbsp;Ph-&nbsp;positive ALL:<\/strong>starting dose is 600 mg taken as 6 capsules&nbsp;<strong>a<\/strong>&nbsp;once daily.<\/li><li><strong>If you are being treated for MDS \/ MPD:<\/strong>starting dose is 400 mg taken as 4 capsules&nbsp;<strong>a<\/strong>&nbsp;once daily.<\/li><li><strong>If you are being treated for HES \/ CEL:<\/strong>starting dose is 100 mg taken as a capsule,&nbsp;<strong>a<\/strong>&nbsp;once daily.&nbsp;Your doctor may decide to increase the&nbsp;dose of&nbsp;one 400 mg to be taken as 4 capsules&nbsp;<strong>a<\/strong>&nbsp;once daily, depending on how you respond to treatment.<\/li><li><strong>If you are being treated for DFSP:<\/strong>The&nbsp;dose is&nbsp;800 mg per day (8 capsules) taken as 4 capsules in the morning and 4 capsules in the evening.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Your doctor will tell you how many capsules of Imatinib Grindeks should be given to your child.&nbsp;The amount of Imatinib Grindex given depends on your child&#8217;s condition, body weight, and height.&nbsp;The total&nbsp;dose&nbsp;one for children and adolescents should not exceed 800 mg for the treatment of CML and 600 mg for the treatment of Ph + ALL.&nbsp;The treatment can either be given to your child as a single dose or the daily&nbsp;dose can&nbsp;be given on two different occasions (half in the morning and a half in the evening).<\/p>\n\n\n\n<p><strong>When and how to take Imatinib Grindeks?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Take Imatinib Grindeks with a meal.&nbsp;<\/strong>It helps to protect against stomach problems when you take Imatinib Grindeks.<\/li><li><strong>Swallow the capsules whole with a large glass of water.&nbsp;<\/strong>Do not open or crush the capsules, unless you have difficulty swallowing (eg in children).<\/li><li>If you can not swallow the capsules, you can open them and pour the powder into a glass of non-carbonated water or apple juice.<\/li><li>If you are a woman of&nbsp;childbearing potential&nbsp;trying to open the capsules, be careful to handle the contents carefully and avoid skin or eye contact or inhalation.&nbsp;Hands should be washed immediately after handling opened capsules.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Imatinib Grindeks than you should &nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested&nbsp;<strong>a<\/strong>&nbsp;medicine,&nbsp;contact&nbsp;<strong>a<\/strong>&nbsp;doctor, hospital, or poison information center&nbsp;<strong>immediately<\/strong>&nbsp;for risk assessment and advice.&nbsp;You may need medical attention.&nbsp;Take the medicine pack with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Imatinib Grindeks<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, take it as soon as you remember.&nbsp;However, skip the missed&nbsp;dose&nbsp;if it is soon time to take the next&nbsp;dose&nbsp;.<\/li><li>Then continue with your normal schedule.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Imatinib Grindeks<\/h2>\n\n\n\n<p>Continue to take Imatinib Grindeks every day for as long as your doctor tells you to.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Tell your doctor immediately if you get any of the following:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10)&nbsp;<strong>or common<\/strong>&nbsp;(may affect up to 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Rapid weight gain.&nbsp;Imatinib Grindeks can make your body bind water (severe&nbsp;fluid retention&nbsp;).<\/li><li>Signs of&nbsp;infection&nbsp;, e.g.&nbsp;fever, frostbite, sore throat or sore mouth.&nbsp;Imatinib Grindeks may reduce the number of&nbsp;white blood cells&nbsp;so that you can get&nbsp;infected&nbsp;more easily&nbsp;.<\/li><li>Sudden bleeding or sores (when you have not injured yourself).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)&nbsp;<strong>or rare<\/strong>&nbsp;(may affect up to 1 in 1,000 users)&nbsp;<strong>:<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest pain, irregular heartbeat (signs of heart problems).<\/li><li>Cough, difficulty breathing or painful breathing (signs of lung problems).<\/li><li>Feeling dizzy, dizzy or fainting (signs of low&nbsp;blood pressure&nbsp;).<\/li><li>Nausea, with decreased appetite, dark urine, yellowing of the skin or eyes (signs of liver problems).<\/li><li>Skin rash,&nbsp;redness&nbsp;with blisters on lips, eyes, skin or mouth, flaking of the skin, fever, raised red or purple skin areas,&nbsp;itching&nbsp;, burning sensation, rash with small blisters (signs of skin problems).<\/li><li>Severe abdominal pain, blood in vomit, stool or urine, black stools (signs of gastrointestinal disease).<\/li><li>Severe decreased urine output, thirst (signs of kidney problems).<\/li><li>Nausea, with diarrhea and vomiting, abdominal pain or fever (signs of intestinal problems).<\/li><li>Severe headache, weakness or paralysis of the legs or face, difficulty speaking, sudden unconsciousness (signs of nervous system problems such as bleeding or swelling of the skull \/ brain).<\/li><li>Paleness, fatigue and shortness of breath with dark urine (signs of low level of&nbsp;red blood cells&nbsp;).<\/li><li>Eye pain or impaired vision, bleeding in the eyes.<\/li><li>Pain in the hips or difficulty walking.<\/li><li>Numb or cold toes and fingers (signs of Raynaud&#8217;s syndrome).<\/li><li>Sudden swelling and&nbsp;redness&nbsp;of the skin (signs of a skin infection called&nbsp;cellulite&nbsp;).<\/li><li>Impaired hearing.<\/li><li>Muscle weakness and muscle cramps with abnormal heart rhythm (signs that indicate changes in the amount of&nbsp;potassium&nbsp;in your blood).<\/li><li>Tendency to get bruises.<\/li><li>Stomach pain with nausea.<\/li><li>Muscle cramps with fever, red-brown urine, pain or weakness in your muscles (signs of muscle problems).<\/li><li>Pelvic pain sometimes with nausea and vomiting, with unexpected vaginal bleeding, dizziness or fainting due to low&nbsp;blood pressure&nbsp;(signs of ovarian or uterine problems).<\/li><li>Nausea, shortness of breath, irregular heartbeat, cloudy urine, fatigue and \/ or joint problems associated with abnormal laboratory values \u200b\u200b(eg high&nbsp;potassium&nbsp;,&nbsp;uric acid&nbsp;and calcium levels, as well as low phosphorus levels in the blood).<\/li><li>Blood clots in small blood vessels (thrombotic microangiopathy).<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Combination of severe skin rash, nausea, fever, high levels of certain&nbsp;white blood cells&nbsp;or yellow skin or eyes (signs of jaundice) with shortness of breath, chest pain \/ discomfort, greatly reduced urine production and feeling of thirst, etc. (signs of treatment-&nbsp;related allergic reaction&nbsp;).<\/li><li>Chronic&nbsp;renal failure&nbsp;.<\/li><li>Recurrence (reactivation) of&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;when you have previously had&nbsp;hepatitis&nbsp;B (a liver infection).<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor immediately<\/strong>&nbsp;if you get any of the above.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;may include:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<p>&#8211; Headache or fatigue.<\/p>\n\n\n\n<p>&#8211; Nausea, vomiting, diarrhea, or indigestion.<\/p>\n\n\n\n<p>&#8211; Skin rash.<\/p>\n\n\n\n<p>&#8211; Muscle cramps or pain in joints, muscles, or bones during treatment with Imatinib Grindeks or after you have stopped taking Imatinib Grindeks.<\/p>\n\n\n\n<p>&#8211; Swelling around joints or swollen eyes.<\/p>\n\n\n\n<p>&#8211; Weight gain.<\/p>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite, weight loss or taste disorders.<\/li><li>Dizziness or weakness.<\/li><li>Sleep problems (&nbsp;insomnia&nbsp;).<\/li><li>Runny eyes with&nbsp;itching&nbsp;,&nbsp;redness&nbsp;and swelling (conjunctivitis), watery eyes or blurred vision.<\/li><li>Nosebleed.<\/li><li>Abdominal pain or distended abdomen, flatulence, heartburn, constipation.<\/li><li>Itching&nbsp;.<\/li><li>Unexpectedly heavy hair loss or thinning of the hair.<\/li><li>Numbness in hands and feet.<\/li><li>Sores in the mouth.<\/li><li>Joint pain with swelling.<\/li><li>Dry&nbsp;mouth&nbsp;, dry skin or dry eyes.<\/li><li>Decreased or increased sensitivity of the skin.<\/li><li>Hot flashes, chills or night sweats.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Redness&nbsp;and \/ or swelling in the palms and soles of the feet which may be accompanied by a stinging sensation or burning pain.<\/li><li>Painful changes in the skin with or without blisters.<\/li><li>Slow growth in children and adolescents.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to side effects that are not mentioned in this information.&nbsp;You can also report&nbsp;side effects&nbsp;directly (see details below).&nbsp;By reporting&nbsp;side effects, you can help increase the safety of medicines.<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>751 03 Uppsala<\/p>\n\n\n\n<p>Website: www.lakemedelsverket.se<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Imatinib Grindeks<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Do not use this medicine if the packaging is damaged or if there are visible signs of injury.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is imatinib (as mesilate).&nbsp;Each Imatinib Grindek capsule contains imatinib mesilate equivalent to 100 mg imatinib.<\/li><li>The other ingredients are: microcrystalline cellulose,&nbsp;colloidal&nbsp;anhydrous silica, crospovidone, talc, magnesium stearate.<\/li><\/ul>\n\n\n\n<p><em>Capsule shell (hard):<\/em>&nbsp;Titanium dioxide (E 171), iron oxide, red (E 172), iron oxide, yellow (E 172), gelatin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Imatinib Grindeks 100 mg capsules are brown-orange hard gelatin capsules, 19 mm long.&nbsp;The content is white to light yellow or brownish-yellow powder.<\/p>\n\n\n\n<p>The capsules are packaged in PVC \/ PVDC \/ aluminum blister.<\/p>\n\n\n\n<p>10 capsules in each blister.<\/p>\n\n\n\n<p>Pack sizes: 60 or 120 capsules.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>AS GRINDEKS<\/p>\n\n\n\n<p>Krustpils iela 53, Riga, LV 1057, Latvia<\/p>\n\n\n\n<p>Tel: +371 67083205<\/p>\n\n\n\n<p>Fax: +371 67083505<\/p>\n\n\n\n<p>Email: grindeks@grindeks.lv<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imatinib Grindeks is a medicine that contains an active substance called imatinib. The drug acts by inhibiting the growth of abnormal cells in the diseases listed below. These include certain types of cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[13132,13162,13120,13158,13163,13161,13125,13123,13160,13122,13121,13159],"class_list":["post-14148","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-imatinib","tag-benefits-of-imatinib-grindeks","tag-imatinib","tag-imatinib-grindeks","tag-imatinib-grindeks-side-effects","tag-imatinib-grindeks-tablet","tag-imatinib-side-effects","tag-imatinib-tablet","tag-what-imatinib-grindeks-is-used-for","tag-what-imatinib-is-used-for","tag-what-is-imatinib","tag-what-is-imatinib-grindeks"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14148"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14148\/revisions"}],"predecessor-version":[{"id":15048,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14148\/revisions\/15048"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}