{"id":14138,"date":"2021-09-25T07:06:27","date_gmt":"2021-09-25T07:06:27","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14138"},"modified":"2021-10-23T11:13:36","modified_gmt":"2021-10-23T11:13:36","slug":"imatinib-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/imatinib-accord\/","title":{"rendered":"Imatinib Accord &#8211; Imatinib uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg and 400 mg&nbsp;film-coated tablets<br>imatinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Imatinib Accord is and what it is used for<\/h2>\n\n\n\n<p>Imatinib Accord is a medicine that contains an active substance called imatinib.&nbsp;The drug acts by&nbsp;inhibiting the&nbsp;growth of abnormal cells in the diseases listed below.&nbsp;These include certain types of cancer.<\/p>\n\n\n\n<p><strong>Imatinib Accord is a treatment for adults and children and adolescents for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Chronic myeloid leukemia&nbsp;(CML).&nbsp;<\/strong>Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;usually help the body fight&nbsp;infection&nbsp;.&nbsp;Chronic myeloid leukemia&nbsp;is a form of&nbsp;leukemia in&nbsp;which certain abnormal&nbsp;white blood cells&nbsp;(so-called myeloid cells) begin to grow out of control.<\/li><li><strong>Philadelphia chromosome-positive&nbsp;acute lymphoblastic leukemia&nbsp;(&nbsp;Ph-&nbsp;positive ALL).&nbsp;<\/strong>Leukemia&nbsp;is a cancer of the white&nbsp;blood cells&nbsp;.&nbsp;These&nbsp;white blood cells&nbsp;normally help the body fight&nbsp;infection&nbsp;.&nbsp;Acute lymphoblastic leukemia&nbsp;is a form of&nbsp;leukemia&nbsp;in which certain abnormal, immature&nbsp;white blood cells&nbsp;(so-called&nbsp;lymphoblasts&nbsp;) begin to grow out of control.&nbsp;Imatinib Accord inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p><strong>Imatinib Accord is also an adult treatment for:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Myelodysplastic \/ myeloproliferative disorders (MDS \/ MPD).&nbsp;<\/strong>These are a group of blood diseases in which certain blood cells begin to grow out of control.&nbsp;Imatinib Accord inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Hypereosinophilic syndrome (HES) and \/ or&nbsp;chronic&nbsp;eosinophilic&nbsp;leukemia&nbsp;(CEL).&nbsp;<\/strong>These are blood diseases in which certain blood cells (so-called&nbsp;eosinophils&nbsp;) begin to grow out of control.&nbsp;Imatinib Accord inhibits the growth of these cells in a certain subset of these diseases.<\/li><li><strong>Dermatofibrosarcoma protuberans (DFSP).&nbsp;<\/strong>DFSP is a cancer of the&nbsp;tissue&nbsp;under the skin in which certain cells begin to grow out of control.&nbsp;Imatinib Accord inhibits the growth of these cells.<\/li><\/ul>\n\n\n\n<p>In the rest of this leaflet, abbreviations will be used when talking about these diseases.<\/p>\n\n\n\n<p>Ask your doctor if you have any questions about how this medicine works or why this medicine has been prescribed for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Imatinib Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Imatinib Accord<\/h2>\n\n\n\n<p>Imatinib Accord will only be prescribed to you by a doctor with medical experience in treating different types of blood cancers or solid&nbsp;tumors.<\/p>\n\n\n\n<p>Follow all of your doctor&#8217;s instructions carefully, although these may differ from the general information in this leaflet.<\/p>\n\n\n\n<p><strong>Do not take Imatinib Accord:<\/strong><\/p>\n\n\n\n<p>&#8211; if you are allergic to imatinib or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n<p>If this applies to you,&nbsp;<strong>do not take Imatinib Accord without&nbsp;<\/strong><strong>telling your doctor.<\/strong><\/p>\n\n\n\n<p>If you think you may be allergic but are not sure, ask your doctor for further advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Imatinib Accord:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had a liver, kidney or heart disease.<\/li><li>if you are taking the medicine levothyroxine due to&nbsp;that your&nbsp;thyroid gland&nbsp;has been removed.<\/li><li>if you have ever had or may now have a&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;.&nbsp;The reason for this is that Imatinib Accord can cause your&nbsp;hepatitis&nbsp;B to become active again, which in some cases can be fatal.&nbsp;Patients will be closely monitored by their physician for signs of this&nbsp;infection&nbsp;before starting treatment.<\/li><li>if you get bruises, bleeding, fever, get very tired and confused when taking Imatinib Accord, contact your doctor.&nbsp;This may be a sign of an injury to the blood vessels called thrombotic microangiopathy (TMA).<\/li><\/ul>\n\n\n\n<p>If any of these apply to you,&nbsp;<strong>tell your doctor before taking Imatinib Accord.<\/strong><\/p>\n\n\n\n<p>You may become more sensitive to the sun while taking Imatinib Accord.&nbsp;It is important to cover exposed areas of the skin and use sunscreen with a high sun protection factor (SPF).&nbsp;These precautions also apply to children.<\/p>\n\n\n\n<p><strong>When taking Imatinib Accord, tell your doctor immediately<\/strong>&nbsp;if you gain weight quickly.&nbsp;Imatinib Accord can cause your body to bind fluid (severe&nbsp;fluid retention&nbsp;).<\/p>\n\n\n\n<p>When you are taking Imatinib Accord, your doctor will regularly check that the medicine is working.&nbsp;You will also be given blood samples and weighed regularly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Imatinib Accord is also a treatment for children and adolescents with CML.&nbsp;There is no experience from children and adolescents with CML under 2 years.&nbsp;There is limited experience from children and adolescents with&nbsp;Ph-positive ALL and very limited experience from children and adolescents with MDS \/ MPD, DFSP, and HES \/ CEL.<\/p>\n\n\n\n<p>Some children and adolescents taking Imatinib Accord may grow more slowly than usual.&nbsp;Your doctor will regularly check your growth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Imatinib Accord<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription (eg&nbsp;paracetamol&nbsp;) and herbal medicines (eg&nbsp;St. John&#8217;s wort&nbsp;).&nbsp;Some medicines may affect the effect of Imatinib Accord when taken together.&nbsp;They may increase or decrease the effect of Imatinib Accord and either leads to more&nbsp;side effects&nbsp;or make Imatinib Accord less effective.&nbsp;Imatinib Accord can do the same for some other medicines.<\/p>\n\n\n\n<p>Tell your doctor if you are taking medicines that prevent the formation of blood clots.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<\/li><li>Imatinib Accord is not recommended during pregnancy unless clearly necessary as it may harm your baby.&nbsp;Your doctor will discuss the possible risks of taking Imatinib Accord during pregnancy.<\/li><li>Women who may become pregnant are advised to use effective contraception during treatment and for 15 days after stopping treatment.<\/li><li>Do not breast-feed during treatment with Imatinib Accord and for 15 days after stopping treatment as it may be harmful to your baby.<\/li><li>Patients who are concerned about their&nbsp;fertility&nbsp;when taking Imatinib Accord are advised to consult their doctor.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may feel dizzy or tired or have blurred vision when using this medicine.&nbsp;If this happens, do not drive or use any tools or machines until you feel well again.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Imatinib Accord<\/h2>\n\n\n\n<p>Your doctor has prescribed Imatinib Accord because you are suffering from a serious illness.&nbsp;Imatinib Accord can help you fight this condition.<\/p>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;It is important that you do this as long as your doctor or pharmacist tells you to.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Do not stop taking Imatinib Accord unless your doctor tells you to.&nbsp;If you can not take the medicine according to your doctor&#8217;s&nbsp;prescription&nbsp;or if you feel that you do not need it anymore, contact your doctor immediately.<\/p>\n\n\n\n<p><strong>How much Imatinib Accord to take?<\/strong><\/p>\n\n\n\n<p><strong>Use for adults<\/strong><\/p>\n\n\n\n<p>Your doctor will tell you exactly how many Imatinib Accord tablets to take.<\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>If you are being treated for KML:<\/strong><\/p>\n\n\n\n<p>Depending on your condition, the usual starting dose is either 400 mg or 600 mg:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>400 mg<\/strong>&nbsp;taken as 4 tablets of 100 mg and 1 tablet of 400 mg of&nbsp;<strong>a<\/strong>&nbsp;once a day,<\/li><li><strong>600 mg<\/strong>&nbsp;taken as 6 tablets of 100 mg and 1 tablet of 400 mg plus 2 tablets of 100 mg,&nbsp;<strong>a<\/strong>&nbsp;once a day.<\/li><\/ul>\n\n\n\n<p>&#8211; At KML, your doctor may prescribe a higher or lower&nbsp;dose&nbsp;depending on how you respond to treatment.&nbsp;If your daily&nbsp;dose&nbsp;is 800 mg (8 tablets of 100 mg or 2 tablets of 400 mg) you should take 4 tablets of 100 mg or 1 tablet of 400 mg in the morning and 4 tablets of 100 mg or 1 tablet of 400 mg in the evening.<\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>If you are being treated for&nbsp;Ph-positive ALL:<\/strong><\/p>\n\n\n\n<p>the starting dose is 600 mg taken as 6 tablets of 100 mg and 1 tablet of 400 mg plus 2 tablets of 100 mg,&nbsp;once daily.<\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>If you are being treated for MDS \/ MPD:<\/strong><\/p>\n\n\n\n<p>the starting dose is 400 mg taken as 4 tablets of 100 mg and 1 tablet of 400 mg&nbsp;once daily.<\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>If you are being treated for HES \/ CEL:<\/strong><\/p>\n\n\n\n<p>the starting dose is 100 mg taken as 1 tablet of 100 mg,&nbsp;once daily.&nbsp;Your doctor may decide to increase the&nbsp;dose of&nbsp;one 400 mg to be taken as 4 tablets of 100 mg and 1 tablet of 400 mg&nbsp;once daily, depending on how you respond to treatment.<\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>If you are being treated for DFSP:<\/strong><\/p>\n\n\n\n<p>The&nbsp;dose is&nbsp;800 mg per day taken as 4 tablets of 100 mg or 1 tablet of 400 mg in the morning and 4 tablets of 100 mg or 1 tablet of 400 mg in the evening.<\/p>\n\n\n\n<p><strong>Use for children and adolescents<\/strong><\/p>\n\n\n\n<p>Your doctor will tell you how many Imatinib Accord tablets to give to your child.&nbsp;The amount of Imatinib Accord given depends on your child&#8217;s condition, body weight, and height.&nbsp;The total&nbsp;dose&nbsp;one for children and adolescents should not exceed 800 mg for CML and 600 mg for&nbsp;Ph-positive ALL.&nbsp;The treatment can either be given to your child as a single dose or alternatively the daily&nbsp;dose can&nbsp;be given on two different occasions (half in the morning and a half in the evening).<\/p>\n\n\n\n<p><strong>When and how to take Imatinib Accord?<\/strong><\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>Take Imatinib Accord with a meal.&nbsp;<\/strong>It helps to protect against stomach problems when you take Imatinib Accord.<\/p>\n\n\n\n<p>&#8211;&nbsp;<strong>Swallow the capsules whole with a large glass of water.<\/strong><\/p>\n\n\n\n<p>If you have difficulty swallowing the tablets, you can dissolve them in a glass of non-carbonated water or apple juice.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Use about 50 ml for a 100 mg tablet or 200 ml for a 400 mg tablet.<\/li><li>Stir with a spoon until the tablet has completely dissolved.<\/li><li>When the tablets are completely dissolved, drink the entire contents of the glass at once.&nbsp;Traces of the dissolved tablet may remain in the glass.<\/li><\/ul>\n\n\n\n<p><strong>How long to take Imatinib Accord?<\/strong><\/p>\n\n\n\n<p>Continue to take Imatinib Accord every day for as long as your doctor tells you to.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Imatinib Accord than you should<\/h2>\n\n\n\n<p>Contact your doctor&nbsp;<strong>immediately<\/strong>&nbsp;if you have accidentally taken too many tablets.&nbsp;You may need medical attention.&nbsp;Take the medicine pack with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Imatinib Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, take it as soon as you remember.&nbsp;However, skip the missed&nbsp;dose&nbsp;if it is soon time to take the next&nbsp;dose&nbsp;.<\/li><li>&#8211; Then continue with your normal schedule.<\/li><li>&#8211; Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;They are usually of mild to moderate severity.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Tell your doctor immediately if you get any of the following:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 in 10 people)&nbsp;<strong>or common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Rapid weight gain.&nbsp;Imatinib Accord can cause your body to bind water (severe&nbsp;fluid retention&nbsp;).<\/li><li>Signs of&nbsp;infection&nbsp;, e.g.&nbsp;fever, frostbite, sore throat or sore mouth.&nbsp;Imatinib Accord can lead to a reduction in the number of&nbsp;white blood cells&nbsp;so that you can get&nbsp;infection&nbsp;more easily&nbsp;.<\/li><li>Sudden bleeding or sores (when you have not injured yourself).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)&nbsp;<strong>or rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest pain, irregular heartbeat (signs of heart problems).<\/li><li>Cough, difficulty breathing or painful breathing (signs of lung problems).<\/li><li>Feeling dizzy, dizzy or fainting (signs of low&nbsp;blood pressure&nbsp;).<\/li><li>Nausea, with decreased appetite, dark-colored urine, yellowing of the skin or eyes (signs of liver problems).<\/li><li>Skin rash,&nbsp;redness&nbsp;with blisters on lips, eyes, skin or mouth, flaking of the skin, fever, raised red or purple skin areas,&nbsp;itching&nbsp;, burning sensation, rash with small blisters (signs of skin problems).<\/li><li>Severe abdominal pain, blood in vomit, stool or urine, black stools (signs of gastrointestinal disease).<\/li><li>Severe decreased urine output, thirst (signs of kidney problems).<\/li><li>Nausea, with diarrhea and vomiting, abdominal pain or fever (signs of intestinal problems).<\/li><li>Severe headache, weakness or paralysis of the legs or face, difficulty speaking, sudden unconsciousness (signs of nervous system problems such as bleeding or swelling of the skull \/ brain).<\/li><li>Paleness, fatigue and shortness of breath with dark urine (signs of low level of&nbsp;red blood cells&nbsp;).<\/li><li>Eye pain or impaired vision, bleeding in the eyes.<\/li><li>Pain in the hips or difficulty walking.<\/li><li>Numb or cold toes and fingers (signs of Raynaud&#8217;s syndrome).<\/li><li>Sudden swelling and&nbsp;redness&nbsp;of the skin (signs of a skin infection called&nbsp;cellulite&nbsp;).<\/li><li>Hearing loss.<\/li><li>Muscle weakness and muscle cramps with abnormal heart rhythm (signs that indicate changes in the amount of&nbsp;potassium&nbsp;in your blood).<\/li><li>Tendency to get bruises.<\/li><li>Stomach pain, with nausea.<\/li><li>Muscle cramps, with fever, red-brown urine, pain or weakness in your muscles (signs of muscle problems).<\/li><li>Pelvic pain sometimes with nausea and vomiting, with unexpected vaginal bleeding, dizziness or fainting due to low&nbsp;blood pressure&nbsp;(signs of ovarian or uterine problems).<\/li><li>Nausea, shortness of breath, irregular heartbeat, cloudy urine, fatigue and \/ or joint problems associated with abnormal laboratory values \u200b\u200b(eg high&nbsp;potassium&nbsp;,&nbsp;uric acid&nbsp;and calcium levels, as well as low phosphorus levels in the blood).<\/li><li>Blood clots in small blood vessels (thrombotic microangiopathy).<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Combination of severe skin rash, nausea, fever, high levels of certain&nbsp;white blood cells&nbsp;or yellow skin or eyes (signs of jaundice) with shortness of breath, chest pain \/ discomfort, greatly reduced urine production and feeling of thirst, etc. (signs of treatment-&nbsp;related allergic reaction&nbsp;).<\/li><li>Chronic&nbsp;renal failure<\/li><li>Recurrence (reactivation) of&nbsp;hepatitis&nbsp;B&nbsp;infection&nbsp;when you have previously had&nbsp;hepatitis&nbsp;B (a liver infection).<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor immediately<\/strong>&nbsp;if you get any of the above.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;may include:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache or fatigue.<\/li><li>Nausea, vomiting, diarrhea or indigestion.<\/li><li>Rash.<\/li><li>Muscle cramps or pain in joints, muscles or bones during treatment with Imatinib Accord or after stopping Imatinib Accord.<\/li><li>Swelling around joints or swollen eyes.<\/li><li>Weight gain.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased appetite, weight loss or taste disorders.<\/li><li>Dizziness or weakness.<\/li><li>Sleep problems (&nbsp;insomnia&nbsp;).<\/li><li>Runny eyes with&nbsp;itching&nbsp;,&nbsp;redness&nbsp;and swelling (conjunctivitis), watery eyes or blurred vision.<\/li><li>Nosebleed.<\/li><li>Abdominal pain or distended abdomen, flatulence, heartburn, constipation.<\/li><li>Itching&nbsp;.<\/li><li>Unexpectedly heavy hair loss or thinning of the hair.<\/li><li>Numbness in hands and feet.<\/li><li>Sores in the mouth.<\/li><li>Joint pain with swelling.<\/li><li>Dry&nbsp;mouth&nbsp;, dry skin or dry eyes.<\/li><li>Decreased or increased sensitivity of the skin.<\/li><li>Hot flashes, chills or night sweats.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Redness&nbsp;and \/ or swelling in the palms and soles of the feet which may be accompanied by a stinging sensation or burning pain.<\/li><li>Painful changes in the skin with or without blisters.<\/li><li>Slow growth in children and adolescents.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;if any of these affect you seriously.<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Imatinib Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton and blister after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/li><li>For PVC \/ PVdC \/ aluminum blisters Store below<br>30 \u00b0 C.<\/li><li>For aluminum \/ aluminum blisters<br>No special precautions for storage.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Do not use if any packaging is damaged or shows signs of having been opened or otherwise handled improperly.<\/li><li>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is imatinib mesylate.&nbsp;Each 100 mg film-coated tablet Imatinib Accord contains 100 mg imatinib (as mesylate).Each 400 mg film-coated tablet Imatinib Accord contains 400 mg imatinib (as mesylate).<\/li><li>The other ingredients are microcrystalline cellulose, crospovidone, hypermellose 6 cps (E464), magnesium stearate and anhydrous&nbsp;colloidal&nbsp;silica.&nbsp;The film coating is made of hypromellose 6 cps (E464), talc (E553b), polyethylene glycol, iron oxide, yellow (E172) and iron oxide, red (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Imatinib Accord 100 mg film-coated tablets are brown-orange, round, biconvex, film-coated tablets, marked &#8220;IM&#8221; and &#8220;T1&#8221; on one side of the breaker, and unlabeled on the other side.<\/p>\n\n\n\n<p>Imatinib Accord 400 mg film-coated tablets are brown-orange, oval, biconvex, film-coated tablets marked &#8220;IM&#8221; and &#8220;T2&#8221; on one side of the breaker, and unlabeled on the other side.<\/p>\n\n\n\n<p>Imatinib Accord 100 mg film-coated tablets are supplied in packs of 20, 60, 120, or 180 tablets, but not all pack sizes may be marketed.<\/p>\n\n\n\n<p>Imatinib Accord 100 mg tablets are also available in perforated single-dose blisters of PVC \/ PVdC \/ aluminum in pack sizes of 30&#215;1, 60&#215;1, 90&#215;1, 120&#215;1 and 180&#215;1 film-coated tablets.<\/p>\n\n\n\n<p>Imatinib Accord 400 mg film-coated tablets are supplied in packs of 10, 30, or 90 tablets, but not all pack sizes may be marketed.<\/p>\n\n\n\n<p>Imatinib Accord 400 mg tablets are also available in perforated single-dose blisters of PVC \/ PVdC \/ aluminum in pack sizes containing 30&#215;1, 60&#215;1 and 90&#215;1 film-coated tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Accord Healthcare SLU<\/p>\n\n\n\n<p>World Trade Center, Moll de Barcelona, \u200b\u200bs \/ n,<\/p>\n\n\n\n<p>Edifici Est 6\u00aa planta,<\/p>\n\n\n\n<p>08039 Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Accord Healthcare Limited<\/p>\n\n\n\n<p>Sage House, 319 Pinner Road<\/p>\n\n\n\n<p>North Harrow,<\/p>\n\n\n\n<p>Middlesex, HA1 4HF<\/p>\n\n\n\n<p>UK<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Accord Healthcare Polska Sp.z oo,<\/p>\n\n\n\n<p>ul.&nbsp;Lutomierska 50,95-200 Pabianice, Poland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Imatinib Accord is a medicine that contains an active substance called imatinib. The drug acts by inhibiting the growth of abnormal cells in the diseases listed below. These include certain types of cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[13132,13185,13120,13181,13184,13125,13123,13186,13183,13122,13121,13182],"class_list":["post-14138","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-imatinib","tag-benefits-of-imatinib-accord","tag-imatinib","tag-imatinib-accord","tag-imatinib-accord-tablet","tag-imatinib-side-effects","tag-imatinib-tablet","tag-side-effects-of-imatinib-accord","tag-what-imatinib-accord-is-used-for","tag-what-imatinib-is-used-for","tag-what-is-imatinib","tag-what-is-imatinib-accord"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14138"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14138\/revisions"}],"predecessor-version":[{"id":15079,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14138\/revisions\/15079"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}