{"id":14120,"date":"2021-09-25T06:50:33","date_gmt":"2021-09-25T06:50:33","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14120"},"modified":"2023-01-07T07:45:18","modified_gmt":"2023-01-07T07:45:18","slug":"idotrim","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/idotrim\/","title":{"rendered":"Idotrim &#8211; Trimethoprim Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Idotrim 100 mg and idotrim 160 mg\u00a0Trimethoprim Tablets<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Idotrim Is And What Is It Used For<\/h2>\n\n\n\n<p>Idotrim is used for urinary tract infections and as a preventative treatment for patients with recurrent urinary tract infections. Idotrim prevents bacterial growth in urinary tract infections.<\/p>\n\n\n\n<p>Trimethoprim contained in Idotrim may also be approved for treating other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Idotrim<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Idotrim<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to trimethoprim or any of the other ingredients of this medicine (listed in section 6).<\/li><li>If you have severe renal or hepatic impairment.<\/li><li>If you have a blood disorder called\u00a0blood dyscrasia.<\/li><li>If you have megaloblastic\u00a0anaemia\u00a0(\u00a0vitamin\u00a0B\u00a0<sub>12\u00a0<\/sub>deficiency\u00a0or\u00a0folate\u00a0).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Idotrim:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have kidney disease<\/li><li>If you have a rare blood disorder called\u00a0porphyria<\/li><li>If you are older or your child is using this medicine for long-term treatment<\/li><li>If you have suspected or confirmed folate deficiency.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor if you suffer from diarrhoea during treatment.<\/p>\n\n\n\n<p>Concomitant intake of trimethoprim with certain other drugs, e.g.\u00a0spironolactone, may lead to severe\u00a0hyperkalemia\u00a0(elevated blood potassium levels).\u00a0Symptoms of severe\u00a0hyperkalemia\u00a0may include <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle cramps<\/li><li>Irregular heartbeat<\/li><li>Diarrhoea<\/li><li>Nausea<\/li><li>Dizziness<\/li><li>Headache<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Idotrim<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;Especially:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Warfarin\u00a0(to prevent blood clotting)<\/li><li>Glibenclamide (for the treatment of\u00a0diabetes\u00a0)<\/li><li>Phenytoin\u00a0(for the treatment of\u00a0epilepsy\u00a0)<\/li><li>Ciclosporin (to prevent transplant rejection)<\/li><li>Antibiotics\u00a0such as rifampicin, dapsone<\/li><li>Zidovudine (for viral infection,\u00a0HIV\u00a0)<\/li><li>Diuretics\u00a0(\u00a0diuretics\u00a0), e.g.\u00a0spironolactone<\/li><li>ACE inhibitors\u00a0(for the treatment of high\u00a0blood pressure\u00a0)<\/li><li>Digoxin\u00a0(for the treatment of heart problems)<\/li><li>Pyrimethamine (for the treatment of\u00a0malaria\u00a0)<\/li><li>Methotrexate (for the treatment of <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a> or your immune system)<\/li><li>Drugs that cause bone marrow suppression.<\/li><\/ul>\n\n\n\n<p>Trimethoprim can affect the test that determines the creatinine concentration in the body.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>The use of Idotrim is not recommended during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Idotrim passes into breast milk but is unlikely to affect breastfed infants.&nbsp;However, consult your doctor if you use Idotrim more than temporarily during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Idotrim has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work requiring increased attention.\u00a0One of the factors that can affect your ability in this regard is the use of drugs due to their effects and\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Idotrim Contains Lactose<\/h2>\n\n\n\n<p>Idotrim contains\u00a0lactose\u00a0.\u00a0If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use Idotrim<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take Idotrim exactly as your doctor has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><li><em>It is important to follow the prescribed course, so the\u00a0infection\u00a0does not flare up again.<\/em><\/li><li>Dose\u00a0one is determined by the doctor, who adjusts it individually for you.<\/li><li><strong>Adults<\/strong><ul><li><em>The recommended\u00a0dose\u00a0for lower uncomplicated <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/urinary-tract-infection\/\">urinary tract infection<\/a>:<\/em><ul><li>150-200 mg twice a day or 300 mg at night.<\/li><\/ul><\/li><li><em>The recommended\u00a0dose\u00a0for long-term treatment:<\/em><ul><li>100 mg at night.<\/li><\/ul><\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use For Children And Adolescents.<\/h2>\n\n\n\n<p><em>The recommended&nbsp;dose&nbsp;for lower uncomplicated urinary tract infection:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Children over 3 months:\u00a0Dose\u00a0one is determined by the doctor, who adjusts it according to the child&#8217;s weight (age) and disease state.<\/li><li>Children over 12 years: 150-200 mg twice daily or 300 mg at night.<\/li><\/ul>\n\n\n\n<p><em>The recommended&nbsp;dose&nbsp;for long-term treatment:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Children over 3 months:\u00a0Dose\u00a0one is determined by the doctor, who adjusts it according to the child&#8217;s weight (age) and disease state.<\/li><li>Children over 12 years: 100 mg at night.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Idotrim Than You Should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Idotrim Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines,\u00a0although not everybody gets them.<\/p>\n\n\n\n<p>Discontinue treatment and contact a doctor or the nearest emergency department immediately if you get any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, tongue or throat<ul><li>Difficulty swallowing<\/li><li>Hives\u00a0and difficulty breathing (\u00a0angioedema may affect up to 1 in 1,000 people).<\/li><\/ul><\/li><li>Prolonged or severe diarrhoea (intestinal inflammation, may occur in up to 1 in 1000 users)<\/li><li>An extremely severe\u00a0allergic reaction\u00a0with skin rash, usually in the form of blisters or sores in the oral cavity and eyes as well as other mucous membranes, such as genitals (may occur in up to 1 in 1000 users).<\/li><li>Severe skin damage (skin detachment of the epidermis and superficial mucous membranes) (may affect up to 1 in 10,000 users).<\/li><\/ul>\n\n\n\n<p>Idotrim can, in rare cases, affect the white\u00a0blood cells\u00a0so that the\u00a0defence against\u00a0infection deteriorates.\u00a0Get an infection with symptoms such as <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">fever<\/a> with severe deterioration of the general condition or fever with local infection symptoms such as sore throat\/pharynx\/mouth or difficulty urinating. You should see a doctor as soon as possible so that a blood test can rule out a lack of\u00a0white blood cells\u00a0(\u00a0agranulocytosis may affect up to 1 in 1000 users).\u00a0It is important that you then have information about your medication.<\/p>\n\n\n\n<p><strong>Other\u00a0side effects\u00a0may occur.<\/strong><\/p>\n\n\n\n<p><em>Common<\/em> Idotrim side effects\u00a0(may affect up to 1 in 10 people): <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea<\/li><li>Vomiting<\/li><li>Tongue inflammation<\/li><li>Itching<\/li><li>Rash<\/li><\/ul>\n\n\n\n<p><em>Uncommon<\/em>\u00a0(may affect up to 1 in 100 people): <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hives<\/li><li>Blood clots (increased or decreased number of certain\u00a0blood cells\u00a0)<\/li><\/ul>\n\n\n\n<p><em>Rare<\/em>\u00a0(may affect up to 1 in 1,000 people):\u00a0<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Meningitis<\/li><li>Hypersensitivity reactions\u00a0(e.g. fever, allergic\u00a0shock\u00a0)<\/li><li>Diarrhoea<\/li><li>Sensitivity to sunlight<\/li><li>Skin changes (sometimes severe)<\/li><li>Inflammation\u00a0of the eye (conjunctivitis)<\/li><li>Blood count changes<\/li><\/ul>\n\n\n\n<p><em>Very rare<\/em>\u00a0(may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Serum disease (e.g. skin rash and swelling<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a> and glandular swelling)<\/li><li>Inflammation\u00a0of the eye (\u00a0uveitis\u00a0)<\/li><li>Elevated levels of\u00a0potassium\u00a0in the blood<\/li><\/ul>\n\n\n\n<p><em>Has been reported<\/em>&nbsp;(cannot be calculated from the available data): Bile stasis, fungal overgrowth in the oral cavity and abdomen.<\/p>\n\n\n\n<p><strong>Reporting of\u00a0side effects\u00a0are<\/strong><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you get any side effects.\u00a0This also applies to\u00a0side effects\u00a0that are not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly (see details below).\u00a0By reporting\u00a0side effects, you can help increase the safety of medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Idotrim<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>No special temperature instructions.\u00a0Store in the original package.\u00a0Sensitive to light.<\/li><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is trimethoprim.\u00a0One tablet contains 100 mg and 160 mg of trimethoprim, respectively.<\/li><li>The other ingredients are\u00a0lactose monohydrate\u00a055 mg and 88 mg, microcrystalline cellulose, maize\u00a0starch, pregelatinised\u00a0starch, crospovidone, magnesium stearate, polysorbate 80, povidone, hypromellose, propylene glycol.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><em>Appearance<\/em><ul><li>100 mg tablets are white, film-coated, round, cup with a notch, and have a diameter of 9 mm.<\/li><li>160 mg tablets are white, film-coated, round, cupped, and 11 mm in diameter.<\/li><\/ul><\/li><li><em>Pack sizes<\/em><ul><li>100 mg tablets: Plastic jars with 30 and 100 tablets.<\/li><li>160 mg tablets: Plastic jars with 14, 20, and 100 tablets.<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Orion Corporation<\/p>\n\n\n\n<p>Orionintie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Orion Corporation Orion Pharma<\/p>\n\n\n\n<p>Orionintie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>Orion Corporation Orion Pharma<\/p>\n\n\n\n<p>Joensuunkatu 7<\/p>\n\n\n\n<p>FI-24100 Salo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>For further information on this medicine, please get in touch with your local representative:<\/p>\n\n\n\n<p>Orion Pharma AB, Danderyd<\/p>\n\n\n\n<p>medinfo@orionpharma.com<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>751 03 Uppsala<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Idotrim is used for urinary tract infections and as a preventative treatment for patients with recurrent urinary tract infections.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[13266,13261,13262,13265,13267,3459,3461,13260,13264,13263,9413,13259],"class_list":["post-14120","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-benefits-of-idotrim","tag-benefits-of-trimethoprim","tag-idotrim","tag-idotrim-tablet","tag-side-effects-of-idotrim","tag-trimethoprim-2","tag-trimethoprim-side-effects","tag-trimethoprim-tablet","tag-what-idotrim-is-used-for","tag-what-is-idotrim","tag-what-is-trimethoprim","tag-what-trimethoprim-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14120","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14120"}],"version-history":[{"count":41,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14120\/revisions"}],"predecessor-version":[{"id":43798,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14120\/revisions\/43798"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14120"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14120"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}