{"id":14112,"date":"2021-09-25T06:46:26","date_gmt":"2021-09-25T06:46:26","guid":{"rendered":"https:\/\/zeepedia.com\/?p=14112"},"modified":"2021-10-23T11:15:25","modified_gmt":"2021-10-23T11:15:25","slug":"idelvion","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/idelvion\/","title":{"rendered":"Idelvion &#8211; Albutrepenonakog alpha uses, dose and side effects"},"content":{"rendered":"\n<p>250 IU, 500 IU, 1000 IU, 2000 IU, and 3500 IU&nbsp;powder and solvent for&nbsp;injection, solution<br>albutrepenonakog alpha (&nbsp;recombinant&nbsp;coagulation factor&nbsp;IX)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What IDELVION is and what it is used for<\/h2>\n\n\n\n<p><strong>What is IDELVION?<\/strong><\/p>\n\n\n\n<p>IDELVION is medicine for&nbsp;haemophilia&nbsp;that replaces natural&nbsp;coagulation factor&nbsp;(clotting factor) IX.&nbsp;The active substance in IDELVION is albutrepenone and alpha (&nbsp;recombinant&nbsp;fusion protein linking coagulation factor IX to albumin (RIX-FP)).<\/p>\n\n\n\n<p>Factor IX is involved in blood clotting.&nbsp;Patients with&nbsp;haemophilia&nbsp;B have a deficiency of this factor, which means that their blood cannot clot as quickly as it should and therefore there is an increased tendency to bleed.&nbsp;IDELVION works by replacing factor IX in patients with&nbsp;haemophilia&nbsp;B so that their blood can clot.<\/p>\n\n\n\n<p><strong>What is IDELVION used for?<\/strong><\/p>\n\n\n\n<p>IDELVION is used for preventing or stopping bleeding caused by a lack of functioning factor IX in patients of all ages with&nbsp;haemophilia&nbsp;B (also known as congenital factor IX deficiency or Christmas disease).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using IDELVION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use IDELVION<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to the active substance (albutrepenonacog alfa) or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are allergic to hamster protein.&nbsp;<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>It is strongly recommended that each time you use IDELVION make a note of the product name and batch number, in order to have control over which products and batches you have used.<\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using IDELVION.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic&nbsp;hypersensitivity reactions&nbsp;may occur.&nbsp;The product contains traces of hamster proteins (see also &#8220;Do not use IDELVION&#8221;).&nbsp;<strong>If symptoms of an&nbsp;allergic reaction&nbsp;occur, stop using the medicine immediately and contact your doctor&nbsp;<\/strong><strong>or treatment center&nbsp;<\/strong><strong>where you are being monitored&nbsp;<\/strong><strong>.&nbsp;Your doctor should inform you of early signs of&nbsp;hypersensitivity reaction&nbsp;.&nbsp;<\/strong>These include hives, generalized skin rash, chest tightness, wheezing, low&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;) and&nbsp;anaphylaxis&nbsp;(a severe&nbsp;allergic reaction&nbsp;that causes severe difficulty breathing or dizziness).<\/li><li>Due to the risk of allergic reactions with factor IX, your first&nbsp;dose&nbsp;of IDELVION should be given under medical supervision where appropriate medical care for allergic reactions can be given.<\/li><li>The&nbsp;<strong>formation of inhibitors<\/strong>&nbsp;(&nbsp;antibodies&nbsp;) is a known complication that has been reported during treatment with IDELVION.&nbsp;The inhibitors cause the treatment to stop working properly.&nbsp;Tell your doctor immediately if your bleeding cannot be controlled with IDELVION.&nbsp;You should be monitored regularly for the formation of inhibitors.<\/li><li>If you have liver or heart disease or if you have recently had major surgery, tell your doctor as there is an increased risk of blood clots (coagulation).<\/li><li>If you need to use a central venous catheter (CVK for&nbsp;injection&nbsp;of IDELVION), the risk of complications should be considered by your doctor, including local&nbsp;infections&nbsp;, bacteria in the blood (&nbsp;bacteremia&nbsp;) and the formation of blood clots in blood vessels (&nbsp;thrombosis&nbsp;) where the catheter is located.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and IDELVION<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/li><li>During pregnancy and lactation, IDELVION should only be given if absolutely necessary.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>IDELVION does not affect the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">IDELVION contains sodium<\/h2>\n\n\n\n<p>This medicine contains up to 8.6 mg&nbsp;sodium&nbsp;(the main ingredient in table salt\/table salt) per&nbsp;vial.&nbsp;This corresponds to 0.4% of the highest recommended daily intake of&nbsp;sodium&nbsp;for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use IDELVION<\/h2>\n\n\n\n<p>Your treatment should be started and carried out under the supervision of a doctor who has experience in the treatment of bleeding disorders.<\/p>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Consult a doctor if you are unsure.<\/p>\n\n\n\n<p>Your doctor will calculate the&nbsp;dose&nbsp;you need of IDELVION.&nbsp;The amount of IDELVION you need and the treatment time depends on:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the severity of your illness<\/li><li>where the bleeding is and how extensive it is<\/li><li>your clinical condition and treatment response<\/li><li>your body weight.<\/li><\/ul>\n\n\n\n<p>IDELVION is administered by your doctor or nurse as an&nbsp;injection&nbsp;into a vein by&nbsp;intravenous, (iv)&nbsp;injection&nbsp;after&nbsp;reconstitution&nbsp;of the powder with the supplied solvent.&nbsp;You or someone else can also&nbsp;administer&nbsp;IDELVION as an IV&nbsp;injection, but only after receiving appropriate training.<\/p>\n\n\n\n<p><strong>If you use more IDELVION then you should<\/strong><\/p>\n\n\n\n<p>Contact your doctor immediately if you inject more IDELVION than your doctor recommended.<\/p>\n\n\n\n<p><strong>If you stop using IDELVION<\/strong><\/p>\n\n\n\n<p>Do not stop using IDELVION without consulting a doctor.<\/p>\n\n\n\n<p><strong>Preparation&nbsp;and&nbsp;<\/strong><strong>administration<\/strong><\/p>\n\n\n\n<p><em><strong>General instructions<\/strong><\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The powder must be mixed with the diluent and withdrawn from the vial while keeping the drug sterile (bacteria-free).&nbsp;Your doctor will show you how to prepare the solution and how to draw the solution correctly from the vial.<\/li><li>IDELVION must not be mixed with other medicinal products or solutions other than those mentioned in section 6.<\/li><li>The solution should be clear and slightly opalescent (semi-transparent), yellow to colorless, ie it may glisten if held up to the light but must not contain any visible particles.&nbsp;After filtering or filling the syringe (see below), the solution should be visually inspected before use.&nbsp;Do not use the solution if it is cloudy or contains flakes or particles.<\/li><li>Any unused product or waste material should be disposed of in accordance with local requirements and as directed by your physician.<\/li><\/ul>\n\n\n\n<p><em><strong>Preparation<\/strong><\/em><\/p>\n\n\n\n<p>Before opening the vials, IDELVION powder and liquid should be warmed to room or body temperature.&nbsp;This can be done either by allowing the bottles to stand at room temperature for about an hour or by holding them in your hands for a few minutes.<\/p>\n\n\n\n<p>DO NOT expose the vials to direct heat.&nbsp;The vials must not be heated above body temperature (37 \u00baC).<\/p>\n\n\n\n<p>Carefully remove the plastic lids from the bottles and clean the surfaces of the rubber stoppers with an alcohol wipe.&nbsp;Allow the vials to dry before opening the Mix2Vial package (containing the transfer kit with filter).&nbsp;Then follow the instructions below.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20150408000028#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/7927a0e0-c542-46cf-b35d-8f34cf3eafa4\" alt=\"Preparation 1\" title=\"Preparation 1\"\/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20150408000028#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/e23a202f-2419-4ead-99f2-4a7dc9a5c247\" alt=\"Preparation 2\" title=\"Preparation 2\"\/><\/a><\/figure>\n\n\n\n<p><em><strong>Commissioning and&nbsp;administration<\/strong><\/em><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20150408000028#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/082f7c5c-0636-48e0-a55e-7e712f9eb0e9\" alt=\"Preparation 3\" title=\"Preparation 3\"\/><\/a><\/figure>\n\n\n\n<p>Use the supplied venipuncture set and insert the needle into a vein.&nbsp;Let the blood flow back to the end of the tube.&nbsp;Attach the syringe to the threaded locking device at the end of the venipuncture set.&nbsp;Slowly inject the reconstituted solution&nbsp;into the vein&nbsp;(as convenient for you, up to a maximum of 5 ml\/min<strong>),<\/strong>&nbsp;according to the instructions given to you by your doctor.&nbsp;Be careful not to get any blood into the syringe with a reconstituted solution.<\/p>\n\n\n\n<p>See if you get any immediate&nbsp;side effects.&nbsp;If you experience any&nbsp;side effects&nbsp;that may be due to the&nbsp;administration&nbsp;of IDELVION,&nbsp;the injection&nbsp;should&nbsp;be discontinued (see also sections 2 and 4).<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>if you get symptoms of an&nbsp;allergic reaction&nbsp;(see below)<\/strong><\/li><li><strong>if you notice that the medicine is not working properly<\/strong><\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been observed with factor IX drugs:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><em>Hypersensitivity&nbsp;s&nbsp;<\/em><em>the allergic<\/em>&nbsp;are possible (less common) and may include these symptoms: hives, skin rash (generalized&nbsp;urticaria&nbsp;), chest tightness, wheezing, low&nbsp;blood pressure&nbsp;and&nbsp;anaphylaxis&nbsp;(a severe&nbsp;allergic reaction&nbsp;that causes breathing difficulties, dizziness).&nbsp;Stop using the medicine and contact a doctor immediately if you get any such symptoms.<\/li><li><em>Inhibitors: the<\/em>&nbsp;drug stops working properly (continued bleeding).&nbsp;You can develop an inhibitor (neutralizing&nbsp;antibody&nbsp;) to factor IX (occurs in an unknown number of users), which means that factor IX no longer works properly.&nbsp;If this happens, stop using the medicine immediately and contact your doctor.<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been observed&nbsp;<strong>commonly<\/strong>&nbsp;with IDELVION (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Injection site reactions<\/li><li>Dizziness<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been&nbsp;<strong>reported uncommonly<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Rash<\/li><li>Eczema<\/li><\/ul>\n\n\n\n<p><strong>Side effects&nbsp;are in children and adolescents<\/strong><\/p>\n\n\n\n<p>Side effects&nbsp;in children are expected to be the same as in adults.<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store IDELVION<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the label and carton.<\/li><li>Do not store above 25 \u00b0 C.<\/li><li>Do not freeze.<\/li><li>Keep the vial in the outer carton.&nbsp;Sensitive to light.<\/li><li>The finished product should preferably be used immediately.<\/li><\/ul>\n\n\n\n<p>If the reconstituted product is not administered immediately, the storage time and conditions before use are the responsibility of the user.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><strong>The active substance is:<\/strong><\/p>\n\n\n\n<p>250 IU per vial: after&nbsp;reconstitution&nbsp;with 2.5 ml of water for injections, the solution contains 100 IU \/ ml albutrepenone and alfa.<\/p>\n\n\n\n<p>500 IU per vial: after&nbsp;reconstitution&nbsp;with 2.5 ml of water for injections, the solution contains 200 IU \/ ml albutrepenone and alfa.<\/p>\n\n\n\n<p>1000 IU per vial: after&nbsp;reconstitution&nbsp;with 2.5 ml of water for injections, the solution contains 400 IU \/ ml albutrepenone and alfa.<\/p>\n\n\n\n<p>2000 IU per vial: after&nbsp;reconstitution&nbsp;with 5 ml of water for injections, the solution contains 400 IU \/ ml albutrepenone and alfa.<\/p>\n\n\n\n<p>3500 IU per vial: after&nbsp;reconstitution&nbsp;with 5 ml of water for injections, the solution contains 700 IU \/ ml albutrepenone and alfa.<\/p>\n\n\n\n<p><strong>Other ingredients are:<\/strong><\/p>\n\n\n\n<p>Sodium citrate, polysorbate 80, mannitol, sucrose, and&nbsp;hydrochloric acid&nbsp;(for&nbsp;pH&nbsp;adjustment)<\/p>\n\n\n\n<p>See the last paragraph in section 2.<\/p>\n\n\n\n<p>Diluent: Water for injections<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>IDELVION is a light yellow to white powder and is supplied with water for injections as&nbsp;diluent.<\/p>\n\n\n\n<p>The reconstituted solution should be clear or slightly opalescent, yellow to colorless, ie it may glisten if held against the light, but it must not contain any visible particles.<\/p>\n\n\n\n<p><strong>Packaging designs:<\/strong><\/p>\n\n\n\n<p>A pack of 250, 500, or 1000 IU contains:<\/p>\n\n\n\n<p>1&nbsp;vial&nbsp;of powder<\/p>\n\n\n\n<p>1&nbsp;vial&nbsp;with 2.5 ml of water for injections<\/p>\n\n\n\n<p>1 transfer set with filter 20\/20<\/p>\n\n\n\n<p>The inner carton contains:<\/p>\n\n\n\n<p>1 5 ml disposable syringe<\/p>\n\n\n\n<p>1 venipuncture set<\/p>\n\n\n\n<p>2 alcohol dryers<\/p>\n\n\n\n<p>1 non-sterile&nbsp;patch<\/p>\n\n\n\n<p>A pack of 2000 IU or 3500 IU contains:<\/p>\n\n\n\n<p>1&nbsp;vial&nbsp;of powder<\/p>\n\n\n\n<p>1&nbsp;vial&nbsp;with 5 ml water for injections<\/p>\n\n\n\n<p>1 transfer set with filter 20\/20<\/p>\n\n\n\n<p>The inner carton contains:<\/p>\n\n\n\n<p>1 10 ml disposable syringe<\/p>\n\n\n\n<p>1 venipuncture set<\/p>\n\n\n\n<p>2 alcohol dryers<\/p>\n\n\n\n<p>1 non-sterile&nbsp;patch<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>CSL Behring GmbH<\/p>\n\n\n\n<p>Emil-von-Behring-Stra\u00dfe 76<\/p>\n\n\n\n<p>35041 Marburg<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>CSL Behring NV<br><br>Tel: +32 15 28 89 20<\/td><td><strong>Lithuania<\/strong>CSL Behring GmbHTel: +4 9 69 30584437<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>This is the FARM BULGARIA LADTel: +359 2 810 3949<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>CSL Behring NVTel: +32 15 28 89 20<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>CSL Behring sroTel: + 420 702 137 233<\/td><td><strong>Hungary<\/strong>CSL Behring Kft.Tel .: +36 1 213 4290<\/td><\/tr><tr><td><strong>Denmark<\/strong>CSL Behring ABTel: +46 8 544 966 70<\/td><td><strong>Malta<\/strong>AM Mangion Ltd.Tel: +356 2397 6333<\/td><\/tr><tr><td><strong>Germany<\/strong>CSL Behring GmbHTel: +49 69 30584437<\/td><td><strong>The Netherlands<\/strong>CSL Behring BVTel: + 31 85 111 96 00<\/td><\/tr><tr><td><strong>Eesti<\/strong>CSL Behring GmbHTel: +4 9 69 30584437<\/td><td><strong>Norway<\/strong>CSL Behring ABTel: +46 8 544 966 70<\/td><\/tr><tr><td><strong>Greece<\/strong>CSL Behring \u0395\u03a0\u0395:\u0397\u03bb: +30 210 7255 660<\/td><td><strong>Austria<\/strong>CSL Behring GmbHTel: +43 1 80101 2463<\/td><\/tr><tr><td><strong>Spain<\/strong>CSL Behring SATel: +34 933 67 1870<\/td><td><strong>Poland<\/strong>CSL Behring Sp.z ooTel: +48 22 213 22 65<\/td><\/tr><tr><td><strong>Croatia<\/strong>Marti Farm doo<br>Tel: +385 1 5588297<\/td><td><strong>Romania<\/strong>Prisum International Trading srlTel: +40 21 322 0171<\/td><\/tr><tr><td><strong>Ireland<\/strong>CSL Behring UK Ltd.Tel: +44 1444 447405<\/td><td><strong>Slovenia<\/strong>MediSanus dooTel: +386 1 25 71 496<\/td><\/tr><tr><td><strong>Iceland<\/strong>CSL Behring ABPhone: +46 8 544 966 70<\/td><td><strong>Slovak Republic<\/strong>CSL Behring sroTel: + 421 911 653 862<\/td><\/tr><tr><td><strong>Italy<\/strong>CSL Behring SpATel: +39 02 34964 200<\/td><td><strong>Finland \/ Finland<\/strong>CSL Behring ABPuh \/ Tel: +46 8 544 966 70<\/td><\/tr><tr><td><strong>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>CSL Behring \u0395\u03a0\u0395:\u0397\u03bb: +30 210 7255 660<\/td><td><strong>Sweden<\/strong>CSL Behring ABTel: +46 8 544 966 70<\/td><\/tr><tr><td><strong>Latvia<\/strong>CSL Behring GmbHTel: +49 69 30584437<\/td><td><strong>United Kingdom<\/strong>CSL Behring UK Ltd.Tel: +44 1444 447405<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>IDELVION is medicine for haemophilia that replaces natural coagulation factor (clotting factor) IX. The active substance in IDELVION is albutrepenone and alpha ( recombinant fusion protein linking coagulation factor IX to albumin (RIX-FP)).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,12116],"tags":[13291,13294,13296,13295,13301,13297,13300,13302,13293,13299,13292,13298],"class_list":["post-14112","post","type-post","status-publish","format-standard","hentry","category-medicines","category-i","tag-albutrepenonakog-alpha","tag-albutrepenonakog-alpha-injection","tag-albutrepenonakog-alpha-side-effects","tag-benefits-of-albutrepenonakog-alpha","tag-benefits-of-idelvion","tag-idelvion","tag-idelvion-injection","tag-idelvion-side-effects","tag-what-albutrepenonakog-alpha-is-used-for","tag-what-idelvion-is-used-for","tag-what-is-albutrepenonakog-alpha","tag-what-is-idelvion"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14112","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=14112"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14112\/revisions"}],"predecessor-version":[{"id":15092,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/14112\/revisions\/15092"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=14112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=14112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=14112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}