{"id":13985,"date":"2021-09-23T07:22:38","date_gmt":"2021-09-23T07:22:38","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13985"},"modified":"2023-02-18T13:25:45","modified_gmt":"2023-02-18T13:25:45","slug":"hypotron","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/hypotron\/","title":{"rendered":"Hypotron &#8211; Midodrine Hydrochloride Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Hypotron 2.5 mg tablets;&nbsp;5 mg tablets, 10 mg Midodrine Hydrochloride Tablets<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Is Hypotron, And What Hypotron Used For?<\/h2>\n\n\n\n<p>The name of your medicine is Hypotron. Hypotron tablets contain the active substance midodrin hydrochloride.\u00a0It belongs to a group of drugs called adrenergic and dopaminergic drugs.<\/p>\n\n\n\n<p>Midodrin hydrochloride is a drug that raises\u00a0blood pressure\u00a0and treats certain severe forms of low\u00a0blood pressure\u00a0in adults when other treatments have not worked.<\/p>\n\n\n\n<p>Midodrin hydrochloride contained in Hypotron may also be approved for treating other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before You Take Hypotron<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Hypotron If:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>You are allergic to midodrin hydrochloride or any of the other ingredients of this medicine (listed in section 6)<\/li><li>You have high\u00a0blood pressure<\/li><li>You have a slow\u00a0heart rate<\/li><li>You have difficulty urinating<\/li><li>You have certain cardiovascular diseases<\/li><li>You have increased eye pressure (\u00a0glaucoma\u00a0) or <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/visual-impairment\/\">visual impairment<\/a> due to\u00a0diabetes.<\/li><li>You have an overactive\u00a0thyroid gland.<\/li><li>You have hormonal disorders caused by a\u00a0tumor\u00a0in the adrenal medulla (\u00a0pheochromocytoma\u00a0)<\/li><li>You have a severe kidney disease<\/li><li>You have prostate enlargement.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Hypotron if you have been told that you have high&nbsp;blood pressure&nbsp;while lying down.&nbsp;If this applies to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your\u00a0blood pressure\u00a0should be\u00a0monitored regularly both when you lie down and when you get up, as there may be a risk that your\u00a0blood pressure\u00a0rises when you lie down, e.g.\u00a0at night.\u00a0If your\u00a0blood pressure\u00a0rises when you lie down and the problem is not remedied by reducing the\u00a0dose\u00a0, treatment with hypotron tablet must be stopped.<\/li><li>You mustn&#8217;t take medicine late in the evening.\u00a0Take the last\u00a0dose of the\u00a0day\u00a0at least 4 hours before bedtime.\u00a0The risk of high\u00a0blood pressure\u00a0when you lie down is less if your head is elevated at night.<\/li><\/ul>\n\n\n\n<p>Also, talk to a doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have a severe disorder of the nervous system (disorder of the\u00a0autonomic nervous system\u00a0) because taking hypotron tablet may lead to a further decrease in\u00a0blood pressure\u00a0when you get up.\u00a0If this happens, treatment with this medicine should be stopped.<\/li><li>If you have blood circulation problems, especially if you have symptoms such as <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> or cramps in the stomach after eating or pain or cramps in the legs when walking.<\/li><li>If you have a prostate disease, you may have difficulty urinating while taking this medicine.<\/li><\/ul>\n\n\n\n<p>Your doctor should check your kidney function and\u00a0blood pressure\u00a0before starting treatment.\u00a0Your blood pressure will be checked continuously during treatment, and the\u00a0dose will\u00a0be adjusted as needed.<\/p>\n\n\n\n<p>You must immediately report symptoms associated with high\u00a0blood pressure, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest pain<\/li><li>Palpitations<\/li><li>Shortness of breath<\/li><li>Headache<\/li><li>Blurred vision<\/li><\/ul>\n\n\n\n<p>Your doctor will decide if your\u00a0dose\u00a0needs to be adjusted or if Hypotron treatment needs to be stopped. Talk to your doctor if any of these warnings apply or have affected you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>This medicine should not be given to children or adolescents under 18 years of age, as the safety and efficacy of Hypotron have not been established in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Hypotron<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines. In particular, tell your doctor or pharmacist if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Concomitant use with these drugs may cause a sharp rise in blood pressure:<ul><li>Reserpine and guanetidine (antihypertensive drugs)<\/li><li>Antihistamines&nbsp;(used to treat&nbsp;allergies&nbsp;)<\/li><li>Thyroid hormone (used if the thyroid gland is not working properly)<\/li><li>Tricyclic antidepressants&nbsp;and&nbsp;MAO inhibitors&nbsp;(both used to treat <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">depression<\/a>)<\/li><li>Other&nbsp;vasoconstrictors&nbsp;(vasoconstrictors) or&nbsp;sympathomimetics&nbsp;(medicines that have a stimulating effect on certain parts of the nervous system)<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Prazosin and Phentolamine (medicines used to treat heart disease) because they prevent the effects of hypotron.<\/li><li>Digitalis preparations (medicines used to treat heart disease) as concomitant use with this medicine may impair heart function.<\/li><li>Corticosteroids\u00a0are fludrocortisone acetate (anti-inflammatory drug) as these drugs may increase the effect of Hypotron.<\/li><li>Drugs that directly or indirectly reduce the heart rate.\u00a0It is recommended that your doctor closely monitor you if Hypotron is used simultaneously as these medicines.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding And Fertility<\/h2>\n\n\n\n<p>This drug is not recommended during pregnancy or in women of childbearing potential not using contraception.\u00a0Tell your doctor if you are pregnant or want to become pregnant during treatment. Do not use this medicine while breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>This medicine is unlikely to affect the ability to drive or use machines.\u00a0However, you should be careful if you experience dizziness or unsteadiness after taking medicine.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work requiring increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections. Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Hypotron 5 Mg Tablets Contain Para-Orange Aluminum Lacquer (E110)<\/h2>\n\n\n\n<p>Para-orange aluminum lacquer (E110) can cause allergic reactions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Hypotron?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine exactly as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><li>Swallow the tablets with water.<\/li><li>This medicine can be taken with or without food.<\/li><li>The breaker is not for dividing the tablet into equal\u00a0doses but for easier swallowing.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How Much To Take Hypotron?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor will decide on a\u00a0dose\u00a0and tell you how long to take medicine.\u00a0The treatment is usually long-lasting.<\/li><li>The recommended starting dose is usually 2.5 mg three times daily.\u00a0This\u00a0dose\u00a0can be increased weekly up to 10 mg three times daily, equivalent to the usual maintenance dose of 30 mg daily.<\/li><li>The recommended daily dose should be evenly distributed over three daily doses.<\/li><\/ul>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Time for the evening dose<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Avoid taking medicine late in the evening.\u00a0Take the last\u00a0dose\u00a0at least 4 hours before bedtime.\u00a0Having your head elevated during the night reduces the risk of high\u00a0blood pressure\u00a0when you lie down.\u00a0See the Warnings and Cautions section of this leaflet for further information.<\/li><li>If you have the impression that the effect of this medicine is too strong or too weak, talk to your doctor or pharmacist.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Hypotron Than You Should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice. An\u00a0overdose\u00a0of the drug can cause:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High\u00a0blood pressure\u00a0(\u00a0hypertension\u00a0), e.g.<ul><li>Palpitations<\/li><li>Shortness of breath<\/li><li>Chest pain<\/li><li>Headache<\/li><li>Blurred vision<\/li><\/ul><\/li><li>Slow heart rate (\u00a0bradycardia\u00a0)<\/li><li>Urination difficulties<\/li><li>Goosebumps<\/li><li>Feeling <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">cold<\/a><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Hypotron<\/h2>\n\n\n\n<p>If you forget to take a\u00a0dose, take the next\u00a0dose\u00a0at the usual time and then continue to take medicine exactly as your doctor has told you.<\/p>\n\n\n\n<p>Please do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose, as it increases the risk of high\u00a0blood pressure\u00a0when lying down.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Taking Hypotron<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>No sudden drop in\u00a0blood pressure\u00a0will occur.<\/li><li>Always consult a doctor if you are considering stopping this medicine.<\/li><li>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Hypotron Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Goosebumps<\/li><li>Itching\u00a0of the scalp<\/li><li>Pain when urinating<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tingling and\u00a0itching<\/li><li>High\u00a0blood pressure\u00a0when lying down<\/li><li>Headache<\/li><li>Nausea<\/li><li>Heartburn<\/li><li>Inflammation\u00a0of the oral mucosa<\/li><li>Redness<\/li><li>Rash<\/li><li>Chills<\/li><li>Difficulty urinating<\/li><\/ul>\n\n\n\n<p><strong>Uncommon hypotron side effects (may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sleep disorders, including difficulty sleeping<\/li><li>Restlessness<\/li><li>Agitation and irritability<\/li><li>Slow heart rate<\/li><li>Urinary incontinence<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Palpitations<\/li><li>Rapid heartbeat<\/li><li>Abnormal liver function, including increase in liver enzymes.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abdominal pain<\/li><li>Vomiting<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diarrhea-in-children\/\">Diarrhea<\/a><\/li><li>Anxiety<\/li><li>Feeling of confusion<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you get any side effects.\u00a0This also applies to any side effects not mentioned in this information.\u00a0You can also report side effects directly to the Medical Products Agency.\u00a0By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Hypotron?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the outer carton and blister after EXP.\u00a0The expiration date is the last day of the specified month.\u00a0Do not store above 30 \u00b0 C.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is midodrine hydrochloride.\u00a0Each tablet contains 2.5 mg, 5, or 10 mg of midodrine hydrochloride.<\/li><li>The other ingredients are microcrystalline cellulose, maize starch, magnesium stearate and anhydrous\u00a0colloidal\u00a0silica.\u00a0Hypotron 5 mg tablets also contain para-orange aluminum lacquer (E110).\u00a0Hypotron 10 mg tablets contain brilliant blue FCF aluminum lacquer (E133).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The 2.5 mg tablets are white, round, and marked on one side with \u201cMID\u201d above the incision and \u201c2.5\u201d below the incision.<\/li><li>The 5 mg tablets are orange, round, and marked on one side with \u201cMID\u201d above the notch and \u201c5\u201d below the notch.<\/li><li>The 10 mg tablets are blue, round and marked on one side with \u201cAPO\u201d and on the other side with \u201cMID\u201d above the scoreline and \u201c10\u201d below the scoreline.<\/li><li>The medicine is available in cartons containing 50 or 100 tablets in aluminum\/aluminum blisters.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Brancaster Pharma Ireland Ltd.<\/p>\n\n\n\n<p>Garadice House<\/p>\n\n\n\n<p>3-4 Fairview<\/p>\n\n\n\n<p>Dublin 3, D03X0Y5<\/p>\n\n\n\n<p>Ireland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When various treatments have failed to treat certain severe kinds of low blood pressure in adults, hypotron is used.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2208],"tags":[13473,13467,13469,13474,13472,13463,13468,13466,13471,13470,13464,13465],"class_list":["post-13985","post","type-post","status-publish","format-standard","hentry","category-medicines","category-h","tag-benefits-of-hypotron","tag-benefits-of-midodrine-hydrochloride","tag-hypotron","tag-hypotron-side-effects","tag-hypotron-tablet","tag-midodrine-hydrochloride","tag-midodrine-hydrochloride-side-effects","tag-midodrine-hydrochloride-tablet","tag-what-hypotron-is-used-for","tag-what-is-hypotron","tag-what-is-midodrine-hydrochloride","tag-what-midodrine-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13985","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13985"}],"version-history":[{"count":55,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13985\/revisions"}],"predecessor-version":[{"id":49673,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13985\/revisions\/49673"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13985"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13985"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13985"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}