<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\nIf you take more Hycamtin than you should<\/h2>\n\n\n\n Ask your doctor or pharmacist immediately if you have taken too many capsules or if a child has accidentally taken the medicine.<\/p>\n\n\n\n
If you forget to take Hycamtin<\/h2>\n\n\n\n Do not take a double dose to make up for a forgotten dose. Take the next dose at the usual time.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n
Serious side effects: tell your doctor<\/strong><\/p>\n\n\n\nThese very common <\/strong>side effects can occur in more than 1 in 10 <\/strong>people<\/strong> treated with Hycamtin:<\/p>\n\n\n\nSigns of infection<\/strong> : Hycamtin may reduce the number of white blood cells and reduce your resistance to infection . This can lead to life-threatening conditions. Symptoms include:fever<\/li> severe deterioration of your general condition<\/li> local symptoms such as sore throat or difficulty urinating (for example, a burning sensation when urinating, which may be due to a urinary tract infection).<\/li><\/ul><\/li> Diarrhea. <\/strong>It can be serious. If you get more than 3 episodes of diarrhea per day, contact your doctor immediately.<\/li>Sometimes severe abdominal pain, fever and possibly diarrhea (in rare cases bloody) can be signs of inflammation in the intestines ( colitis<\/em> ).<\/li><\/ul>\n\n\n\nThis rare <\/strong>side effect can occur in up to <\/strong>1 in 1,000 people<\/strong> treated with Hycamtin:<\/p>\n\n\n\nPneumonia<\/strong> ( interstitial lung disease<\/em> ): You are most at risk if you have a pre-existing lung disease, have had radiation therapy to your lungs, or if you have previously taken medication that caused lung damage. Signs of this can be:breathing difficulties<\/li> cough<\/li> fever.<\/li><\/ul><\/li><\/ul>\n\n\n\nContact your doctor immediately<\/strong> if you get symptoms of any of these conditions as it may be necessary to be hospitalized.<\/p>\n\n\n\nVery common side effects are<\/strong><\/p>\n\n\n\nThese may occur in more than 1 in 10 people<\/strong> treated with Hycamtin:<\/p>\n\n\n\nFeeling of general weakness and tiredness (temporary anemia <\/em>( anemia )). In some cases, you may need a blood transfusion .<\/li>Easier to get bruises and bleeding, due to a decrease in the number of coagulating cells in the blood. This can lead to major bleeding from relatively small wounds such as small cuts. In rare cases, this can lead to severe bleeding ( hemorrhage )<\/em> . Talk to your doctor for advice on how to minimize the risk of bleeding.<\/li>Weight loss and loss of appetite ( anorexia<\/em> ), fatigue, weakness.<\/li>Nausea, vomiting.<\/li> Hair loss.<\/li><\/ul>\n\n\n\nCommon side effects are<\/strong><\/p>\n\n\n\nThese can occur in up to 1 in 10 people<\/strong> treated with Hycamtin:<\/p>\n\n\n\nAllergic or hypersensitivity s<\/em> (including rash).<\/li>Inflammation and sores in the mouth, tongue or gums.<\/li> Fever.<\/li> Stomach ache, constipation, indigestion.<\/li> General feeling of discomfort.<\/li> Skin itching.<\/li><\/ul>\n\n\n\nUncommon side effects are<\/strong><\/p>\n\n\n\nThese can occur in up to 1 in 100 people<\/strong> treated with Hycamtin:<\/p>\n\n\n\nYellowish skin.<\/li><\/ul>\n\n\n\nRare side effects are<\/strong><\/p>\n\n\n\nThese can occur in up to 1 in 1,000 people<\/strong> treated with Hycamtin:<\/p>\n\n\n\nSevere allergic or anaphylactic<\/em> reactions.<\/li>Swelling due to fluid retention ( angioedema<\/em> ).<\/li>Itchy rash (or hives<\/em> ).<\/li><\/ul>\n\n\n\nSide effects are without known frequency<\/strong><\/p>\n\n\n\nThe frequency of some side effects is not known (derived from spontaneous reports and the frequency can not be calculated from the available data)<\/p>\n\n\n\n
Severe abdominal pain, nausea, vomiting of blood, black or bloody stools (possible symptoms of gastrointestinal perforation [gastrointestinal perforation]).<\/li> Sores in the mouth, difficulty swallowing, abdominal pain, nausea, vomiting, diarrhea, bloody stools (possible signs and symptoms of inflammation of the mucous membranes of the mouth, stomach and \/ or intestines [mucositis]).<\/li><\/ul>\n\n\n\nReporting of side effects<\/em><\/p>\n\n\n\nIf you get any side effects, talk to your doctor, pharmacist, or nurse. This also applies to any side effects not mentioned in this information. You can also report side effects directly to the Medical Products Agency. By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n
5. How to store Hycamtin<\/h2>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton.<\/p>\n\n\n\n
Store in a refrigerator (2\u00baC-8\u00baC).<\/p>\n\n\n\n
Do not freeze.<\/p>\n\n\n\n
Store the blister in the outer carton. Sensitive to light.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\nThe active substance is<\/strong> topotecan. Each capsule contains 0.25 mg or 1 mg of topotecan (as hydrochloride).<\/li>The other ingredients are:<\/strong> hydrogenated vegetable oil, glyceryl monostearate, gelatin, titanium dioxide (E171) and only for 1 mg capsules; red iron oxide (E172). The capsules are printed with black ink containing black iron oxide (E172), shellac, anhydrous ethanol , propylene glycol, isopropyl alcohol, butanol, concentrated ammonia solution and potassium hydroxide.<\/li><\/ul>\n\n\n\nWhat the medicine looks like and contents of the pack<\/h2>\n\n\n\n Hycamtin 0.25 mg capsules are opaque, white to off-white, and marked with \u201cHycamtin\u201d and \u201c0.25 mg\u201d.<\/p>\n\n\n\n
Hycamtin 1 mg capsules are pink and marked with \u201cHycamtin\u201d and \u201c1 mg\u201d.<\/p>\n\n\n\n
Hycamtin 0.25 mg and 1 mg are available in packs of 10 capsules.<\/p>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n Novartis Europharm Limited<\/p>\n\n\n\n
Vista Building<\/p>\n\n\n\n
Elm Park, Merrion Road<\/p>\n\n\n\n
Dublin 4<\/p>\n\n\n\n
Ireland<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nNovartis Pharmac\u00e9utica SA<\/p>\n\n\n\n
Gran Via de les Corts Catalanes, 764<\/p>\n\n\n\n
08013 Barcelona<\/p>\n\n\n\n
Spain<\/p>\n\n\n\n
Novartis Pharma GmbH<\/p>\n\n\n\n
Roonstrasse 25<\/p>\n\n\n\n
90429 Nuremberg<\/p>\n\n\n\n
Germany<\/p>\n\n\n\n
GlaxoSmithKline Manufacturing SpA<\/p>\n\n\n\n
Strada Provinciale Asolana 90<\/p>\n\n\n\n
43056 San Polo di Torrile<\/p>\n\n\n\n
Parma<\/p>\n\n\n\n
Italy<\/p>\n\n\n\n
Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\nBelgium \/ Belgique \/ Belgien<\/strong>Novartis Pharma NVTel: +32 2 246 16 11<\/td>Lithuania<\/strong>Novartis Pharma Services Inc.Tel: +370 5 269 16 50<\/td><\/tr>Bulgaria<\/strong>Novartis Bulgaria EOODTel: +359 2 489 98 28<\/td>Luxembourg \/ Luxemburg<\/strong>Novartis Pharma NVTel: +32 2 246 16 11<\/td><\/tr>Czech Republic<\/strong>Novartis sroTel: +420 225 775 111<\/td>Hungary<\/strong>Novartis Hungary Kft.Tel .: +36 1 457 65 00<\/td><\/tr>Denmark<\/strong>Sandoz A \/ STel: +45 63 95 10 00<\/td>Malta<\/strong>Novartis Pharma Services Inc.Tel: +356 2122 2872<\/td><\/tr>Germany<\/strong>Novartis Pharma GmbHTel: +49 911 273 0<\/td>The Netherlands<\/strong>Novartis Pharma BVTel: +31 26 37 82 555<\/td><\/tr>Eesti<\/strong>Novartis Pharma Services Inc.Tel: +372 66 30 810<\/td>Norway<\/strong>Sandoz A \/ STel: +45 63 95 10 00<\/td><\/tr>Greece<\/strong>Novartis (Hellas) AEBE:\u0397\u03bb: +30 210 281 17 12<\/td>Austria<\/strong>Novartis Pharma GmbHTel: +43 1 86 6570<\/td><\/tr>Spain<\/strong>BEXAL PHARMACEUTICALS, SATel: +34 900 456 856<\/td>Poland<\/strong>Novartis Poland Sp. z ooTel .: +48 22 375 4888<\/td><\/tr>France<\/strong>SandozTel: +33 800 45 57 99<\/td>Portugal<\/strong>Novartis Farma – Pharmaceutical Products, SATel: +351 21 000 8600<\/td><\/tr>Croatia<\/strong>Novartis Hrvatska dooTel. +385 1 6274 220<\/td>Romania<\/strong>Sandoz SRLTel: +40 21 40751 60<\/td><\/tr>Ireland<\/strong>Novartis Ireland LimitedTel: +353 1 260 12 55<\/td>Slovenia<\/strong>Novartis Pharma Services Inc.Tel: +386 1 300 75 50<\/td><\/tr>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td>Slovak Republic<\/strong>Novartis Slovakia sroTel: +421 2 5542 5439<\/td><\/tr>Italy<\/strong>Novartis Farma SpATel: +39 02 96 54 1<\/td>Finland \/ Finland<\/strong>Novartis Finland OyPuh \/ Tel: +358 (0) 10 6133 200<\/td><\/tr>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>Novartis Pharma Services Inc.:\u0397\u03bb: +357 22 690 690<\/td>Sweden<\/strong>Sandoz A \/ STel: +45 63 95 10 00<\/td><\/tr>Latvia<\/strong>SIA \u201cNovartis Baltics\u201dTel: +371 67 887 070<\/td>United Kingdom (Northern Ireland)<\/strong>Novartis Ireland LimitedTel: +44 1276 698370<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"Hycamtin is used to treat small cell lung cancer that has recurred after chemotherapy.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2208],"tags":[13604,13598,13600,13603,13605,13594,13597,13599,13602,13601,13595,13596],"class_list":["post-13945","post","type-post","status-publish","format-standard","hentry","category-medicines","category-h","tag-benefits-of-hycamtin","tag-benefits-of-topotecan","tag-hycamtin","tag-hycamtin-capsule","tag-hycamtin-side-effects","tag-topotecan","tag-topotecan-capsule","tag-topotecan-side-effects","tag-what-hycamtin-is-used-for","tag-what-is-hycamtin","tag-what-is-topotecan","tag-what-topotecan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13945","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13945"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13945\/revisions"}],"predecessor-version":[{"id":15226,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13945\/revisions\/15226"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13945"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13945"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13945"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}