{"id":13942,"date":"2021-09-23T06:48:34","date_gmt":"2021-09-23T06:48:34","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13942"},"modified":"2021-11-02T10:35:47","modified_gmt":"2021-11-02T10:35:47","slug":"hyalgan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/hyalgan\/","title":{"rendered":"Hyalgan &#8211; Sodium hyaluronate uses, dose and side effects"},"content":{"rendered":"\n<p>10 mg \/ ml\u00a0injection\u00a0solution<br>of sodium hyaluronate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Hyalgan is and what it is used for<\/h2>\n\n\n\n<p>Hyalgan contains sodium hyaluronate, which is a body-specific substance that is found in the body&#8217;s joints, among other things.&nbsp;In the case of joint wear and tear (&nbsp;osteoarthritis&nbsp;), the levels of sodium hyaluronate in the synovial fluid fall.&nbsp;By&nbsp;injecting the&nbsp;substance&nbsp;directly into the joint, the body is stimulated to produce more sodium hyaluronate.<\/p>\n\n\n\n<p>Hyalgan is used to treat mild to moderate&nbsp;osteoarthritis&nbsp;of the knee joint.&nbsp;The drug reduces pain and improves joint function.&nbsp;The effect lasts for a few months.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Hyalgan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Hyalgan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sodium hyaluronate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if the bone to be injected has a reduced outflow of blood or&nbsp;lymph&nbsp;.<\/li><li>if you are allergic to chicken protein.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If your skin in the injection site is infected or affected by another disease.<\/li><li>If your knee joint is severely inflamed.<\/li><li>Hypersensitivity reactions&nbsp;may occur, but as the product is highly purified, it is very uncommon.<\/li><li>Injection&nbsp;must be given in a careful and hygienic manner to minimize the risk of&nbsp;infection&nbsp;.<\/li><li>Before treatment with Hyalgan, any excess synovial fluid should be removed.<\/li><li>Hyalga must not be injected into blood vessels.<\/li><li>Experience of treating children is lacking.<\/li><li>One should avoid strenuous physical activity and carrying heavy hours after&nbsp;injection&nbsp;one.<\/li><li>Hyalgan should also not be used at the same time as disinfectants that contain so-called quaternary ammonium salts, as these can destroy the active substance.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Hyalgan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Hyalgan<\/h2>\n\n\n\n<p>Hyalgan should not be injected into the knee joint at the same time as any other drug is injected into the same joint, as there is no experience of this.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy:<\/em>&nbsp;Experience with Hyalgan during pregnancy is limited.<\/p>\n\n\n\n<p><em>Breast-feeding:<\/em>&nbsp;Sodium hyaluronate passes into breast milk but is unlikely to affect the baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Hyalgae can in rare cases cause pain and swelling in the knee.&nbsp;This can affect safety when driving a vehicle.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Hyalgan contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, ie essentially &#8216;sodium-free.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Hyalgan<\/h2>\n\n\n\n<p>Hyalgae will be given to you by healthcare professionals, as an&nbsp;injection&nbsp;into the knee joint.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Hyalgan than you should&nbsp;<\/h2>\n\n\n\n<p>If you have received too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Rare (affects less than 1 user in 1,000):<\/em><\/p>\n\n\n\n<p>Local reactions: pain, vomiting, swelling, irritation,&nbsp;inflammation&nbsp;,&nbsp;redness&nbsp;, reduced joint mobility, discomfort, feeling hot, hypersensitivity,&nbsp;itching&nbsp;, rash.<\/p>\n\n\n\n<p><em>Very rare (affects less than 1 user in 10,000):<\/em><\/p>\n\n\n\n<p>Local reactions: bleeding, lump, lump, numbness, blistering,&nbsp;inflammation&nbsp;of the joint capsule or joint, joint stiffness,&nbsp;infection&nbsp;in the joint, (severe)&nbsp;hypersensitivity reactions&nbsp;, various types of skin rashes and redness,&nbsp;eczema&nbsp;,&nbsp;itching&nbsp;,&nbsp;hives&nbsp;.&nbsp;General fever, fever, serum sickness (&nbsp;delayed hypersensitivity reaction&nbsp;such as&nbsp;itching&nbsp;, rash, fever, joint pain and fatigue), various types of swelling such as swelling of the oral and throat mucosa and face.<\/p>\n\n\n\n<p>Stop taking Hyalgan and contact a doctor immediately if you get any of the following symptoms (&nbsp;angioedema&nbsp;):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, tongue or throat<\/li><li>difficulty swallowing<\/li><li>hives&nbsp;and difficulty breathing<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Hyalgan<\/h2>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store in the original package.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;dat.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is sodium hyaluronate 10 mg \/ ml.<\/li><li>The other ingredients are sodium chloride, disodium phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Hyalgan&nbsp;injection&nbsp;is a clear and viscous solution.<\/p>\n\n\n\n<p><em>Pack sizes:<\/em><\/p>\n\n\n\n<p>Vial&nbsp;glass with rubber stopper and aluminum seal: 1&#215;2 ml (unit dose), 5&#215;2 ml (single dose).<\/p>\n\n\n\n<p>Pre-filled&nbsp;syringe&nbsp;in glass with plastic flask and rubber seal: 1&#215;2 ml (single dose), 5&#215;2 ml (single dose).<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Takeda Pharma AB<\/p>\n\n\n\n<p>Vasagatan 7, 6 tr<\/p>\n\n\n\n<p>111 20 Stockholm<\/p>\n\n\n\n<p>Tel.&nbsp;08-731 28 00<\/p>\n\n\n\n<p>Email: infosweden@takeda.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hyalgan contains sodium hyaluronate, which is a body-specific substance that is found in the body&#8217;s joints, among other things. In the case of joint wear and tear ( osteoarthritis ), the levels of sodium hyaluronate in the synovial fluid fall. By injecting the substance directly into the joint, the body is stimulated to produce more sodium hyaluronate.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2208],"tags":[13616,13610,13612,13615,13617,13606,13609,13611,13614,13613,13607,13608],"class_list":["post-13942","post","type-post","status-publish","format-standard","hentry","category-medicines","category-h","tag-benefits-of-hyalgan","tag-benefits-of-sodium-hyaluronate","tag-hyalgan","tag-hyalgan-injection","tag-hyalgan-side-effects","tag-sodium-hyaluronate","tag-sodium-hyaluronate-injection","tag-sodium-hyaluronate-side-effects","tag-what-hyalgan-is-used-for","tag-what-is-hyalgan","tag-what-is-sodium-hyaluronate","tag-what-sodium-hyaluronate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13942","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13942"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13942\/revisions"}],"predecessor-version":[{"id":15227,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13942\/revisions\/15227"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13942"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13942"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13942"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}