{"id":13850,"date":"2021-09-21T06:33:25","date_gmt":"2021-09-21T06:33:25","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13850"},"modified":"2021-11-02T10:07:54","modified_gmt":"2021-11-02T10:07:54","slug":"hexyon","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/hexyon\/","title":{"rendered":"Hexyon &#8211; Vaccine uses, dose and side effects"},"content":{"rendered":"\n<p>injection,&nbsp;suspension<\/p>\n\n\n\n<p>Vaccine against&nbsp;diphtheria, tetanus, pertussis (acellular, component),&nbsp;hepatitis&nbsp;B (rDNA), polio (inactivated), and&nbsp;<em>Haemophilus influenzae<\/em>&nbsp;type b conjugate (&nbsp;adsorbed&nbsp;)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Hexyon is and what it is used for<\/h2>\n\n\n\n<p>Hexyon (DTaP-IPV-&nbsp;HB&nbsp;-Hib) is a vaccine used to protect against infectious diseases.<\/p>\n\n\n\n<p>Hexyon helps protect against&nbsp;diphtheria, tetanus, pertussis,&nbsp;hepatitis&nbsp;B, polio, and serious diseases caused by&nbsp;<em>Haemophilus influenzae<\/em>&nbsp;type b. Hexyon is given to children from six weeks of age.<\/p>\n\n\n\n<p>The vaccine works by getting the body to produce its protection (&nbsp;antibodies&nbsp;) against bacteria and&nbsp;viruses&nbsp;that cause these various infections:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Diphtheria&nbsp;is an infectious disease that usually first affects the throat.&nbsp;In the throat,&nbsp;infection&nbsp;causes&nbsp;a pain and swelling that can lead to suffocation.&nbsp;Bacteria that cause the disease also produce a&nbsp;toxin&nbsp;(poison) that can damage the heart, kidneys and nerves.<\/li><li>tetanus (&nbsp;tetanus&nbsp;) is usually caused by tetanus bacteria entering the body through a deep wound.&nbsp;The bacteria produce a&nbsp;toxin&nbsp;(poison) that causes muscle spasms which lead to difficulty breathing and the risk of suffocation.<\/li><li>whooping cough (pertussis) is a highly contagious disease that affects the respiratory tract.&nbsp;The disease causes severe cough that can cause breathing problems.&nbsp;The cough often has a &#8220;peeking&#8221; sound.&nbsp;The cough can last for one to two months or longer.&nbsp;Whooping cough can also cause ear infections, respiratory tract infections (&nbsp;bronchitis&nbsp;) that can last for a long time,&nbsp;pneumonia&nbsp;, seizures, brain damage and even death.<\/li><li>hepatitis&nbsp;B is caused by the&nbsp;hepatitis&nbsp;B&nbsp;virus&nbsp;.&nbsp;It causes the liver to swell (become inflamed).&nbsp;In some people, the&nbsp;virus&nbsp;can&nbsp;remain in the body for a long time and can eventually cause serious liver problems, including&nbsp;liver cancer.<\/li><li>polio (poliomyelitis) is caused by&nbsp;viruses&nbsp;that affect the nerves.&nbsp;It can lead to paralysis or muscle weakness, usually in the legs.&nbsp;Paralysis of muscles that control breathing and swallowing can cause death.<\/li><li>infection&nbsp;with&nbsp;<em>Haemophilus influenzae<\/em>&nbsp;type b (often called just Hib) are serious bacterial infections that can cause&nbsp;meningitis&nbsp;(&nbsp;inflammation&nbsp;of the outer membranes of the brain), which can lead to brain damage, deafness,&nbsp;epilepsy&nbsp;or&nbsp;partial&nbsp;blindness.&nbsp;Infection&nbsp;can also cause&nbsp;inflammation&nbsp;and swelling in the throat, which in turn leads to difficulty breathing and swallowing;&nbsp;infection&nbsp;can affect other parts of the body such as&nbsp;the blood, lungs, skin, bone tissue and joints.<\/li><\/ul>\n\n\n\n<p><strong>Important information about how the vaccine works<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hexyon only helps to protect against these diseases if they are caused by the bacteria and&nbsp;viruses for&nbsp;which the vaccine is intended.&nbsp;Your child can get diseases with similar symptoms if they are caused by other bacteria or&nbsp;viruses&nbsp;.<\/li><li>The vaccine does not contain any live bacteria or&nbsp;viruses&nbsp;and can not cause any of the infectious diseases that it protects against.<\/li><li>This vaccine does not protect against&nbsp;infection&nbsp;caused by other types of&nbsp;<em>Haemophilus influenzae&nbsp;<\/em>, nor against&nbsp;meningitis&nbsp;caused by other&nbsp;microorganisms&nbsp;.<\/li><li>Hexyon does not protect against hepatitis infection caused by other&nbsp;viruses&nbsp;such as hepatitis A,&nbsp;hepatitis&nbsp;C and hepatitis E or other liver pathogens.<\/li><li>Because symptoms of&nbsp;hepatitis&nbsp;B take a long time to develop, it is possible that undetected hepatitis B&nbsp;infection&nbsp;may occur at the time of vaccination.&nbsp;The vaccine may not be able to prevent hepatitis B&nbsp;infection&nbsp;in such cases.<\/li><li>As with all vaccines, Hexyon may not provide protection in 100% of the children who receive the vaccine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before your child receives Hexyon<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Hexyon<\/h2>\n\n\n\n<p>To ensure that Hexyon is suitable for your child, it is important to talk to a doctor or nurse if any of the points listed below apply to your child.&nbsp;If there is anything you do not understand, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<p><strong>Do not use Hexyon if your child:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have had respiratory problems or swelling of the face (&nbsp;anaphylactic reaction&nbsp;) after&nbsp;administration&nbsp;of Hexyon<\/li><li>have had an&nbsp;allergic reaction<ul><li>against the active substances<\/li><li>against any of the other ingredients listed in section 6<\/li><li>against glutaraldehyde, formaldehyde,&nbsp;neomycin&nbsp;, streptomycin or polymyxin B as these substances are used during the manufacturing process.<\/li><li>after previous&nbsp;administration&nbsp;of Hexyon or other vaccines containing&nbsp;diphtheria&nbsp;, tetanus, pertussis, polio,&nbsp;hepatitis&nbsp;B or Hib<\/li><\/ul><\/li><li>have had a severe reaction affecting the brain (&nbsp;encephalopathy&nbsp;) within 7 days after a previous&nbsp;dose&nbsp;of a pertussis vaccine (acellular or whole cell pertussis)<\/li><li>have an uncontrolled disease state or serious illness that affects the brain and nervous system (uncontrolled neurological disorder) or uncontrolled&nbsp;epilepsy&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before vaccination about your child:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have a moderate or high fever or an&nbsp;acute&nbsp;illness (eg fever, sore throat, cough, cold or&nbsp;flu&nbsp;).&nbsp;Vaccination with Hexyon may need to be postponed until your child feels better.<\/li><li>have had any of the following after receiving the pertussis vaccine, as the decision to give additional&nbsp;doses&nbsp;of pertussis vaccine needs to be carefully considered:<ul><li>fever at 40 \u00b0 C or above within 48 hours after vaccination due to no other identifiable cause.<\/li><li>collapse or shock-like condition with hypotonic-hyporesponsive episode (loss of energy) within 48 hours after vaccination.<\/li><li>persistent and inconsolable crying lasting 3 hours or more and occurring within 48 hours after vaccination.<\/li><li>seizures with or without fever that occur within 3 days after vaccination.<\/li><\/ul><\/li><li>previously had&nbsp;Guillain-Barr\u00e9 syndrome&nbsp;(temporary&nbsp;inflammation&nbsp;of the nerves causing pain, paralysis and sensory disturbances) or brachial&nbsp;neuritis&nbsp;(severe pain and reduced mobility in the arm and shoulder) after receiving a vaccine containing tetanus toxoid (an inactivated form of tetanus vaccine).&nbsp;In this case, the decision to give additional vaccines containing tetanus toxoid should be evaluated by a physician.<\/li><li>follows a treatment that suppresses the immune system (the body&#8217;s natural defenses) or has a disease that causes a weakened immune system.&nbsp;In these cases, the&nbsp;immune response&nbsp;to the vaccine&nbsp;may be&nbsp;reduced.&nbsp;Then it is normally recommended that the vaccination be postponed until the end of the treatment or the disease.&nbsp;Children with long-term problems with the immune system such as&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;(&nbsp;AIDS&nbsp;) can still be Hexyon but the protection may not be as good as in children whose immune system is healthy.<\/li><li>suffers from an&nbsp;acute&nbsp;or&nbsp;chronic&nbsp;disease, including chronic renal impairment or&nbsp;renal failure&nbsp;(kidneys do not function properly).<\/li><li>suffers from an undiagnosed disease of the brain or uncontrolled&nbsp;epilepsy&nbsp;.&nbsp;Your doctor will then assess the potential benefits of vaccination.<\/li><li>have a bleeding disorder that causes slight bruising or bleeding for a long time after minor wounds.&nbsp;Your doctor will tell you if your child can get Hexyon.<\/li><\/ul>\n\n\n\n<p>Fainting can occur after, or even before, the needle stick.&nbsp;Therefore, tell your doctor or nurse if your child has previously fainted in connection with needle sticks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines or vaccines and Hexyon<\/h2>\n\n\n\n<p>Tell your doctor or nurse if your child is taking, has recently taken, or might take any other medicines or vaccines.<\/p>\n\n\n\n<p>Hexyon can be given at the same time as other vaccines such as pneumococcal vaccines, measles-mumps-rubella vaccines, rotavirus vaccines, or meningococcal vaccines.<\/p>\n\n\n\n<p>When Hexyon is given at the same time as other vaccines, the&nbsp;injections&nbsp;will&nbsp;be given in different places.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Hexyon contains phenylalanine, potassium and sodium<\/h2>\n\n\n\n<p>Hexyon contains 85 micrograms of phenylalanine per 0.5 ml&nbsp;dose.&nbsp;Phenylalanine can be harmful if you have phenylketonuria (PKU), a rare, inherited disease that leads to the accumulation of high levels of phenylalanine in your body.<\/p>\n\n\n\n<p>Hexyon contains less than 1 mmol (39 mg)&nbsp;potassium&nbsp;and less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per&nbsp;dose, ie essentially &#8216;potassium free and &#8216;sodium-free.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Hexyon<\/h2>\n\n\n\n<p>Hexyon is given to your child by a doctor or nurse who is trained in the use of vaccines and who can handle less common severe allergic reactions to the&nbsp;injection&nbsp;(see section 4. Possible&nbsp;side effects&nbsp;).<\/p>\n\n\n\n<p>Hexyon is given as an&nbsp;injection&nbsp;into the muscle (&nbsp;intramuscular route of&nbsp;administration, im) in the upper part of your baby&#8217;s leg or upper arm.&nbsp;The vaccine is never given in a blood vessel, in or under the skin.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is as follows:<\/p>\n\n\n\n<p>First vaccination series (primary vaccination)<\/p>\n\n\n\n<p>Your child will receive either two&nbsp;injections&nbsp;given in an interval of two months or three&nbsp;injections&nbsp;given in an interval of one to two months (at least four weeks apart).&nbsp;This vaccine should be used according to the local vaccination program.<\/p>\n\n\n\n<p>Additional&nbsp;injection&nbsp;(booster)<\/p>\n\n\n\n<p>After the first series of injections, your child will receive a booster dose, according to local recommendations, at least 6 months after the last&nbsp;dose of&nbsp;one in the first vaccination series.&nbsp;Your doctor will tell you when this&nbsp;dose&nbsp;should be given.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you miss a dose of Hexyon<\/h2>\n\n\n\n<p>If your child misses a scheduled&nbsp;injection, you must discuss it with your doctor or nurse who will decide when the missed&nbsp;dose&nbsp;should be given.<\/p>\n\n\n\n<p>It is important to follow the instructions from the doctor or nurse so that your child completes the entire vaccination series, otherwise, your child may not have complete protection against the diseases.<\/p>\n\n\n\n<p>If you have any further questions on the use of this vaccine, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this vaccine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Severe allergic reactions&nbsp;<\/strong><strong>(&nbsp;anaphylactic reaction&nbsp;)<\/strong><\/p>\n\n\n\n<p>Contact a doctor IMMEDIATELY if any of these symptoms occur after your child has been injected:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>breathing difficulties<\/li><li>bluish discoloration of tongue or lips<\/li><li>rash<\/li><li>swelling of the face or neck<\/li><li>sudden and severe malaise with falling&nbsp;blood pressure&nbsp;causing dizziness and unconsciousness, increased heart rate associated with difficulty breathing.<\/li><\/ul>\n\n\n\n<p>These signs or symptoms (signs and symptoms of&nbsp;anaphylactic reaction&nbsp;) usually occur very soon after receiving an&nbsp;injection&nbsp;and while the child is still in the clinic or doctor&#8217;s office.<\/p>\n\n\n\n<p>Severe allergic reactions are rare (may affect up to 1 in 1,000 people) after vaccination with this vaccine.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>If your child experiences any of the following&nbsp;side effects, talk to&nbsp;your&nbsp;doctor, pharmacist, or nurse.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Very common&nbsp;side effects&nbsp;(may affect more than 1 in 10 people) are:<ul><li>loss of appetite (&nbsp;anorexia&nbsp;)<\/li><li>crying<\/li><li>drowsiness (&nbsp;somnolence&nbsp;)<\/li><li>vomiting<\/li><li>pain,&nbsp;redness&nbsp;or swelling at the injection site<\/li><li>irritability<\/li><li>fever (body temperature 38 \u00b0 C or higher).<\/li><\/ul><\/li><li>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people) are:<ul><li>abnormal crying (persistent crying)<\/li><li>diarrhea<\/li><li>induration&nbsp;at the injection site (&nbsp;induration&nbsp;).<\/li><\/ul><\/li><li>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people) are:<ul><li>allergic reaction<\/li><li>tubercle at the injection site<\/li><li>high fever (body temperature 39.6 \u00b0 C or higher).<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people) are:<ul><li>rash<\/li><li>major injection site reactions (greater than 5 cm), including extensive swelling of the arm or leg, extending from the injection site over one or more joints.&nbsp;These reactions begin within 24-72 hours after vaccination and may be associated with&nbsp;redness&nbsp;, warmth, tenderness or pain at the injection site and resolve within 3\u20135 days without the need for treatment.<\/li><li>seizures with or without fever.<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Very rare&nbsp;side effects&nbsp;(may affect up to 1 in 10,000 people) are:<ul><li>episodes when your child goes into a shock-like state or is pale, limp and uncontactable for a period of time (hypotonic reactions or hypotonic-hyporesponsive episodes, HHE).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Any&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Isolated cases of other&nbsp;side effects&nbsp;not listed above have been reported with other vaccines containing&nbsp;diphtheria, tetanus, pertussis, poliomyelitis,&nbsp;hepatitis&nbsp;B or Hib and not directly with Hexyon:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>temporary&nbsp;inflammation&nbsp;of nerves causing pain, paralysis and sensory disturbances (&nbsp;Guillain-Barr\u00e9 syndrome&nbsp;) as well as severe pain and reduced mobility of the arm and shoulder (brachial&nbsp;neuritis&nbsp;) have been reported after&nbsp;administration&nbsp;of vaccine containing tetanus<\/li><li>inflammation&nbsp;of several nerves causing sensory disturbances or weakness in the&nbsp;extremities&nbsp;(polyradiculoneuritis), facial paralysis, visual disturbances, sudden blurred vision or loss of vision (&nbsp;optic&nbsp;neuritis&nbsp;),&nbsp;inflammatory&nbsp;disease of the brain and spinal cord (demyelination of the&nbsp;central nervous system&nbsp;,&nbsp;multiple sclerosis&nbsp;) have been reported after&nbsp;administration&nbsp;of a vaccine containing&nbsp;hepatitis&nbsp;B&nbsp;antigen<\/li><li>swelling or&nbsp;inflammation&nbsp;of the brain (encephalopathy \/ encephalitis).<\/li><li>in children born very prematurely (at or before the 28th week of pregnancy) longer than normal breathing intervals may occur for 2-3 days after vaccination<\/li><li>swelling of one or both feet and lower&nbsp;extremities&nbsp;which may occur together with a bluish discoloration of the skin (cyanosis),&nbsp;redness&nbsp;, small areas of bleeding under the skin (transient purpura) and severe crying after vaccination with vaccine containing&nbsp;<em>Haemophilus influenzae<\/em>&nbsp;type b. About this reaction occurs usually after the first (primary)&nbsp;injections&nbsp;and occurs within the first hours after vaccination.&nbsp;All symptoms go away completely within 24 hours without the need for treatment.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Hexyon<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and label after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/p>\n\n\n\n<p>Do not freeze.<\/p>\n\n\n\n<p>Store in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are per&nbsp;dose&nbsp;(0.5 ml)&nbsp;<sup>1<\/sup>&nbsp;:<\/li><li><\/li><\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Diphtheria toxoid<\/td><td>not less than 20 IU&nbsp;<sup>2<\/sup><\/td><\/tr><tr><td>Tetanus toxoid<\/td><td>not less than 40 IU&nbsp;<sup>2.3<\/sup><\/td><\/tr><tr><td><em>Bordetella pertussis&nbsp;&#8211;&nbsp;antigen&nbsp;is<\/em><\/td><td>&nbsp;<\/td><\/tr><tr><td>Pertussis toxoid<\/td><td>25 micrograms<\/td><\/tr><tr><td>Filamentous hemagglutinin<\/td><td>25 micrograms<\/td><\/tr><tr><td>Poliovirus (inactivated)&nbsp;<sup>4<\/sup><\/td><td>&nbsp;<\/td><\/tr><tr><td>Type 1 (Mahoney)<\/td><td>40 D antigen units&nbsp;<sup>5<\/sup><\/td><\/tr><tr><td>Type 2 (MEF-1)<\/td><td>8 D antigen units&nbsp;<sup>5<\/sup><\/td><\/tr><tr><td>Type 3 (Saukett)<\/td><td>32 D antigen units&nbsp;<sup>5<\/sup><\/td><\/tr><tr><td>Hepatitis&nbsp;B surface antigen&nbsp;<sup>6<\/sup><\/td><td>10 micrograms<\/td><\/tr><tr><td><em>Haemophilus influenzae<\/em>&nbsp;type b polysaccharide<\/td><td>12 micrograms<\/td><\/tr><tr><td>(polyribosyl ribitol phosphate)<\/td><td>&nbsp;<\/td><\/tr><tr><td>conjugated to tetanus protein<\/td><td>22\u201336 micrograms<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em><sup>1<\/sup>&nbsp;Adsorbed on aluminum hydroxide, hydrated (0.6 mg Al&nbsp;<sup>3+<\/sup>&nbsp;)<\/em><\/p>\n\n\n\n<p><em><sup>2<\/sup>&nbsp;IU international unit<\/em><\/p>\n\n\n\n<p><em><sup>3<\/sup>&nbsp;Or equivalent activity determined by an immunogenicity evaluation<\/em><\/p>\n\n\n\n<p><em><sup>4<\/sup>&nbsp;Cultivated in Vero cells<\/em><\/p>\n\n\n\n<p><em><sup>5<\/sup>&nbsp;corresponding antigen amounts in the vaccine<\/em><\/p>\n\n\n\n<p><em><sup>6<\/sup>&nbsp;Cultured in yeast cells Hansenula polymorpha using&nbsp;recombinant DNA&nbsp;technology<\/em><\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p>disodium hydrogen phosphate, potassium dihydrogen phosphate, <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tribonate\/\">trometamol<\/a>, sucrose, essential&nbsp;amino acids&nbsp;including L-phenylalanine, sodium hydroxide and \/ or acetic acid and \/ or&nbsp;hydrochloric acid&nbsp;(for&nbsp;pH&nbsp;adjustment) and water for injections.<\/p>\n\n\n\n<p>The vaccine may contain traces of glutaraldehyde, formaldehyde,&nbsp;neomycin, streptomycin, and polymyxin B.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Hexyon was provided as&nbsp;an injection,&nbsp;suspension&nbsp;in a&nbsp;vial&nbsp;(0.5 ml).<\/p>\n\n\n\n<p>Hexyon is available in a pack containing 10 vials.<\/p>\n\n\n\n<p>The normal appearance of the vaccine after shaking is a whitish and cloudy&nbsp;suspension.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorization Holder:<br>Sanofi Pasteur Europe, 14 Espace Henry Vall\u00e9e, 69007 Lyon, France<\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>Sanofi Pasteur, 1541 avenue Marcel M\u00e9rieux, 69280 Marcy l&#8217;Etoile, France<\/p>\n\n\n\n<p>Sanofi Pasteur, Incarville Industrial Park, 27100 Val de Reuil, France<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<p>Sanofi AB<\/p>\n\n\n\n<p>Tel: +46 8-634 50 00<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hexyon (DTaP-IPV- HB -Hib) is a vaccine used to protect against infectious diseases.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2208],"tags":[13764,13758,13762,13765,13761,13763,2356,13760,13759],"class_list":["post-13850","post","type-post","status-publish","format-standard","hentry","category-medicines","category-h","tag-benefits-of-hexyon","tag-hexyon","tag-hexyon-dosage","tag-hexyon-side-effects","tag-hexyon-vaccine","tag-side-effects-of-hexyon","tag-vaccine","tag-what-hexyon-is-used-for","tag-what-is-hexyon"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13850","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13850"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13850\/revisions"}],"predecessor-version":[{"id":15277,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13850\/revisions\/15277"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13850"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13850"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}