{"id":13738,"date":"2021-09-20T08:01:54","date_gmt":"2021-09-20T08:01:54","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13738"},"modified":"2021-11-02T09:52:05","modified_gmt":"2021-11-02T09:52:05","slug":"heminevrin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/heminevrin\/","title":{"rendered":"Heminevrin &#8211; Clomethiazole disilate uses, dose and side effects"},"content":{"rendered":"\n<p>300 mg&nbsp;soft capsules<br>clomethiazole disilate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Heminevrin is and what it is used for<\/h2>\n\n\n\n<p>Heminevrin has sedative, sleep-inducing, and antispasmodic effects due to the inhibitory effect of the drug on some of the brain&#8217;s functions.<\/p>\n\n\n\n<p>Heminevrin capsules are used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>confusion, anxiety and difficulty sleeping in geriatric care<\/li><li>treatment of various symptoms after alcohol abuse<\/li><\/ul>\n\n\n\n<p>Clomethiazole disilate contained in Heminevrin may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Heminevrin<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Heminevrin:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to clomethiazole disilate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have poor lung function<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Heminevrin.<\/p>\n\n\n\n<p>If you have&nbsp;sleep apnea&nbsp;syndrome, impaired lung function, liver damage, or impaired kidney function, consult a physician before starting treatment with Heminevrin.&nbsp;The same applies to people who are at risk of brain or heart complications during the treatment (due to the risk of low&nbsp;blood pressure&nbsp;and palpitations), this is especially true of elderly patients.<\/p>\n\n\n\n<p>Heminevrin can be addictive and there is a risk that the body will get used to Heminevrin during prolonged use and that the effect will thus diminish.&nbsp;A period of poor sleep can occur when you stop taking Heminevrin and therefore Heminevrin should only be used for a short time.<\/p>\n\n\n\n<p>Concomitant use of Heminevrin and alcohol should be avoided (risk of inhibition of brain function).&nbsp;The same risk exists with the concomitant use of other drugs with inhibitory effects on some of the brain&#8217;s functions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Children and adolescents under 18 years of age should not take Heminevrin soft capsules.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Heminevrin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>Heminevrin may affect or be affected by certain medicines containing the following active substances:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cimetidine (medicine for&nbsp;stomach ulcers&nbsp;)<\/li><li>Chlorzoxazone (muscle relaxant)<\/li><li>Carbamazepine (drugs against&nbsp;epilepsy&nbsp;)<\/li><li>Propranolol (medicine for high&nbsp;blood pressure&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Heminevrin with alcohol<\/h2>\n\n\n\n<p>Concomitant use of Heminevrin and alcohol should be avoided (see \u201cWarnings and Precautions\u201d).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy:<\/em>&nbsp;Clometiazole should not be used during pregnancy unless there are strong reasons for use.&nbsp;Talk to your doctor before using Heminevrin during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding:<\/em>&nbsp;Clomethiazole is excreted in human milk but is unlikely to affect the breast-fed baby.&nbsp;However, consult a physician before using Heminevrin during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>When treating with Heminevrin capsules, avoid driving and using machines.&nbsp;This is because the medicine may reduce your ability to react.&nbsp;When Heminevrin capsules are used as a sleeping pill, day-after-day effects may occur even if they are uncommon.&nbsp;The risk increases when consuming alcohol.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Heminevrin contains sorbitol<\/h2>\n\n\n\n<p>One Heminevrin capsule contains 7 mg sorbitol.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Heminevrin<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Always follow your doctor&#8217;s&nbsp;prescription&nbsp;and the instructions on the pharmacy label.&nbsp;Dose&nbsp;one is determined by the doctor who adjusts it individually for you.<\/p>\n\n\n\n<p>The soft capsules should be swallowed whole with a sufficient amount of water.&nbsp;Other modes of administration, such as rectal administration or chewing or dividing the capsules, are not recommended.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Heminevrin than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Heminevrin<\/h2>\n\n\n\n<p>Take the missed&nbsp;dose&nbsp;as soon as you remember.&nbsp;If it is soon time for your next&nbsp;dose, skip the missed&nbsp;dose.&nbsp;Do not take a double&nbsp;dose&nbsp;(two&nbsp;doses&nbsp;at the same time) to compensate for a missed&nbsp;dose&nbsp;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Heminevrin<\/h2>\n\n\n\n<p>A period of poor sleep can occur when you stop taking Heminevrin.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Stop taking Heminevrin and contact a doctor immediately if you get any of the following symptoms:<\/strong><\/p>\n\n\n\n<p>Sudden wheezing, swelling of the lips, tongue and throat or body, rash, fainting or difficulty swallowing (&nbsp;allergic reaction&nbsp;).<\/p>\n\n\n\n<p>This is a rare side effect and affects less than 1 in 1,000 people.<\/p>\n\n\n\n<p><em>Common&nbsp;<\/em><em>(affects more than 1 user in 100):<\/em>&nbsp;Irritation of the nose and eyes (may decrease or disappear with continued treatment).<\/p>\n\n\n\n<p><em>Uncommon&nbsp;<\/em><em>(affects less than 1 user in 100):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastrointestinal disorders (acid regurgitation, stomach pain, nausea, diarrhea, vomiting)<\/li><li>Itching<\/li><li>Hives<\/li><li>Runny nose and nasal congestion<\/li><li>Increased mucus production in the throat and trachea<\/li><li>Elevated liver enzyme levels (goes back when you stop taking the medicine)<\/li><li>Headache<\/li><\/ul>\n\n\n\n<p><em>Rare&nbsp;<\/em><em>(affects less than 1 user in 1,000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reaction<\/li><li>Bladder-like rash<\/li><li>Low&nbsp;blood pressure<\/li><li>Liver effects including jaundice<\/li><\/ul>\n\n\n\n<p><em>No known frequency (cannot be calculated from the available data):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stinging sensations (ant crawls)<\/li><li>Severe&nbsp;hypersensitivity reaction&nbsp;(anaphylactic&nbsp;shock&nbsp;)<\/li><li>Impaired respiratory function<\/li><li>Cardiac arrest<\/li><li>Facial edema<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Heminevrin<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is clomethiazole 192 mg equivalent to clomethiazole disilate 300 mg.<\/li><li>The other ingredients are medium&nbsp;chain triglycerides&nbsp;, gelatin,&nbsp;glycerol&nbsp;85%, mannitol, sorbitol (sweetener), hydrogenated partially hydrolysed&nbsp;starch&nbsp;, titanium dioxide (dye E 171), brown iron oxide (dye E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Heminevrin capsules are soft and gray-brown.&nbsp;They are provided in glass jars with 25 or 3 x 100 capsules.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>CHEPLAPHARM Arzneimittel GmbH<\/p>\n\n\n\n<p>Ziegelhof 24<\/p>\n\n\n\n<p>17489 Greifswald<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>CHEPLAPHARM Arzneimittel GmbH<\/p>\n\n\n\n<p>Ziegelhof 23-24<\/p>\n\n\n\n<p>17489 Greifswald<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>For further information on this medicine, please contact:<\/strong><\/p>\n\n\n\n<p>Propharma Group AB<\/p>\n\n\n\n<p>Fleminggatan 18<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Tel.&nbsp;08-21 54 45<\/p>\n\n\n\n<p>Fax.&nbsp;08- 21 54 46<\/p>\n\n\n\n<p>Email: pharmacovigilance.SE@propharmagroup.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Heminevrin has sedative, sleep-inducing, and antispasmodic effects due to the inhibitory effect of the drug on some of the brain&#8217;s functions.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2208],"tags":[13875,13880,13871,13874,13876,13877,13881,13882,13873,13879,13872,13878],"class_list":["post-13738","post","type-post","status-publish","format-standard","hentry","category-medicines","category-h","tag-benefits-of-clomethiazole-disilate","tag-benefits-of-heminevrin","tag-clomethiazole-disilate","tag-clomethiazole-disilate-capsule","tag-clomethiazole-disilate-side-effects","tag-heminevrin","tag-heminevrin-capsule","tag-heminevrin-side-effects","tag-what-clomethiazole-disilate-is-used-for","tag-what-heminevrin-is-used-for","tag-what-is-clomethiazole-disilate","tag-what-is-heminevrin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13738"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13738\/revisions"}],"predecessor-version":[{"id":15319,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13738\/revisions\/15319"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}