{"id":13736,"date":"2021-09-20T07:59:17","date_gmt":"2021-09-20T07:59:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13736"},"modified":"2021-11-02T09:52:40","modified_gmt":"2021-11-02T09:52:40","slug":"hemangiol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/hemangiol\/","title":{"rendered":"Hemangiol &#8211; Propranolol uses, dose and side effects"},"content":{"rendered":"\n<p>3.75 mg \/ ml&nbsp;oral&nbsp;solution<br>propranolol<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What HEMANGIOL is and what it is used for<\/h2>\n\n\n\n<p><strong>What HEMANGIOL is<\/strong><\/p>\n\n\n\n<p>The name of the drug is HEMANGIOL.&nbsp;The active substance is propranolol.<\/p>\n\n\n\n<p>Propranolol belongs to a group of medicines called&nbsp;beta-blockers.<\/p>\n\n\n\n<p><strong>What it is used for<\/strong><\/p>\n\n\n\n<p>This medicine is used to treat a condition called a hemangioma.&nbsp;A hemangioma is a collection of extra blood vessels that have formed a lump in or under the skin.&nbsp;Hemangiomas can be superficial or deep.&nbsp;They are sometimes called &#8220;strawberry marks&#8221; because the surface of a hemangioma resembles a strawberry.<\/p>\n\n\n\n<p>Hemangiol treatment should be started in infants aged 5 weeks to 5 months when:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the location and \/ or extent of the damage is life-threatening or functional (may damage vital organs or senses such as sight or hearing);<\/li><li>the hemangioma is sore (ie wounds on the skin that do not heal) and painful, and \/ or does not get better with regular wound care;<\/li><li>there is a risk of permanent scarring or disfigurement.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before your child gets HEMANGIOL<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not give HEMANGIOL<\/h2>\n\n\n\n<p>About your child:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>has been born prematurely and has not reached 5 weeks of corrected age (the corrected age is the age a premature baby would have had if he \/ she had been born at the estimated time).<\/li><li>is allergic to propranolol or any of the other ingredients of this medicine (listed in section 6).&nbsp;An&nbsp;allergic reaction&nbsp;can manifest itself as a rash,&nbsp;itching&nbsp;or shortness of breath.<\/li><li>have&nbsp;asthma&nbsp;or have previously had difficulty breathing.<\/li><li>has a slow heart rate for its age.&nbsp;Consult a doctor if you are unsure.<\/li><li>have heart problems (such as arrhythmias and&nbsp;heart failure&nbsp;).<\/li><li>have very low&nbsp;blood pressure&nbsp;.<\/li><li>have circulatory problems that cause toes and fingers to become numb and turn white.<\/li><li>have easy to get low blood sugar.<\/li><li>have high&nbsp;blood pressure&nbsp;caused by a&nbsp;tumor&nbsp;on the adrenal gland.&nbsp;This is called a &#8220;pheochromocytoma&#8221;.<\/li><\/ul>\n\n\n\n<p>If you are breast-feeding your baby, and if you are taking medicines that must not be used with HEMANGIOL, (see &#8220;If you are breast-feeding your baby&#8221; and &#8220;Other medicines and HEMANGIOL&#8221;),&nbsp;<strong>do not give<\/strong>&nbsp;this medicine to your child.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><strong>Before your child receives HEMANGIOL, tell your doctor:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If your child has problems with their liver or kidneys.&nbsp;This medicine is not recommended in case of renal or hepatic impairment.<\/li><li>If your child has had an&nbsp;allergic reaction&nbsp;before, for whatever reason (eg medicines or nutritional products, etc.).&nbsp;An&nbsp;allergic reaction&nbsp;can manifest itself as a rash,&nbsp;itching&nbsp;or shortness of breath.<\/li><li>If your child has&nbsp;psoriasis&nbsp;(a skin condition that causes red, dry scales of thickened skin), this medicine may worsen the symptoms of this condition.<\/li><li>If your child has&nbsp;diabetes&nbsp;.&nbsp;In&nbsp;diabetes&nbsp;, your child&#8217;s blood sugar level should be checked more often.<\/li><li>If your child has PHACE syndrome (a combination of hemangiomas and vascular malformations such as blood vessels in the brain), this medicine may increase the risk of&nbsp;stroke&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>Important signs to pay attention to after&nbsp;administering&nbsp;HEMANGIOL<\/strong><\/p>\n\n\n\n<p><strong>Risk of low&nbsp;blood pressure&nbsp;and slow&nbsp;heart rate<\/strong><\/p>\n\n\n\n<p>HEMANGIOL can lower&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;) and&nbsp;heart rate&nbsp;(&nbsp;bradycardia&nbsp;).&nbsp;This is why your child will be closely monitored clinically and the heart rate will be monitored for 2 hours after taking the first&nbsp;dose&nbsp;one or after an increase in&nbsp;dose&nbsp;one.&nbsp;Thereafter, the doctor will periodically examine the child during treatment.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Contact your doctor immediately if your child has symptoms such as&nbsp;fatigue, chills, paleness, bluish skin,<\/strong> or fainting when he\/she<strong> gets HEMANGIOL.<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Risk of low blood sugar<\/strong><\/p>\n\n\n\n<p>This medicine may obscure warning signs of low blood sugar (hypoglycemia), especially if the child does not eat if he vomits, or in case of overdose.&nbsp;These characters can be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Mild: pallor, fatigue, sweating, tremors, palpitations, anxiety, hunger, difficulty waking up.<\/li><li>Severe: abnormal amount of sleep, less contact, poor appetite, lowering of body temperature, seizures, shortness of breath, unconsciousness.<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Feed your child regularly during treatment to avoid low blood sugar.&nbsp;If your child does not eat, develops another disease,<\/strong> or vomits, the&nbsp;dose&nbsp;should be&nbsp;skipped.&nbsp;DO NOT GIVE HEMANGIOL TO YOUR CHILD UNTIL IT EATS PROPERLY AGAIN.<br>If your child shows signs of low blood sugar while receiving HEMANGIOL, try to get your child to drink a <strong>fluid that contains sugar and, if symptoms persist, contact a doctor immediately or go directly to the hospital.<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Risks of&nbsp;bronchospasm&nbsp;(difficulty breathing)<\/strong><\/p>\n\n\n\n<p>Discontinue treatment and contact your doctor immediately if, after giving HEMANGIOL to your child, you notice the following symptoms that indicate&nbsp;bronchospasm&nbsp;(temporary contraction of the trachea leading to difficulty breathing): cough, rapid breathing, or difficulty breathing or wheezing, possibly in combination with bluish skin.<\/p>\n\n\n\n<p><strong>Risk of&nbsp;hyperkalemia<\/strong><\/p>\n\n\n\n<p>HEMANGIOL may increase the level of&nbsp;potassium&nbsp;in the blood (hyperkalemia).&nbsp;If the hemangioma is large and sore, your baby&#8217;s potassium levels in the blood should be measured.<\/p>\n\n\n\n<p><strong>If your child is to be anesthetized (get anesthesia)<\/strong><\/p>\n\n\n\n<p>Tell your doctor that your child is getting HEMANGIOL.&nbsp;Your child may have low&nbsp;blood pressure&nbsp;if he\/she is given certain anesthetics at the same time as treatment with this medicine (see &#8220;Other medicines and HEMANGIOL&#8221;).&nbsp;HEMANGIOL treatment may need to be stopped at least 48 hours before anesthesia.<\/p>\n\n\n\n<p><strong>If you are breast-feeding your baby<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor before giving this medicine.<\/li><li>Do not give this medicine to your child if you are taking medicines that must not be used with HEMANGIOL (see &#8220;Other medicines and HEMANGIOL&#8221;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and HEMANGIOL<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor, pharmacist or nurse if you are giving, have recently given or might give other medicines to your child.&nbsp;HEMANGIOL may alter the effect of other medicines, and some medicines may affect the effect of HEMANGIOL.<\/li><li>If you are breast-feeding your baby, it is also important to tell your doctor, pharmacist or nurse which medicines you are taking, as these may pass into breast milk and affect the treatment of your baby.&nbsp;Your doctor will decide if you need to stop breast-feeding or not.<\/li><\/ul>\n\n\n\n<p>You must tell your doctor or pharmacist if you (if you are breast-feeding) or your baby is taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drugs for&nbsp;diabetes&nbsp;.<\/li><li>Medicines for cardiovascular problems such as irregular heartbeat, chest pain or angina, high&nbsp;blood pressure&nbsp;,&nbsp;heart failure&nbsp;.<\/li><li>Drugs for the treatment of anxiety and depression as well as more serious mental health problems, and&nbsp;epilepsy&nbsp;.<\/li><li>Drugs for the treatment of&nbsp;tuberculosis&nbsp;.<\/li><li>Medicines for the treatment of pain and&nbsp;inflammation&nbsp;.<\/li><li>Drugs used to lower blood fats.<\/li><li>Drugs used in anesthesia and anesthesia.<\/li><\/ul>\n\n\n\n<p><strong>If you have any further questions, ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HEMANGIOL contains sodium and propylene glycol<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, ie&nbsp;essentially &#8216;&nbsp;sodium-free.&nbsp;is next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<p>This medicine contains 2.08 mg propylene glycol \/ kg \/ day.&nbsp;If your child is younger than 4 weeks, talk to a doctor or pharmacist before giving this child this medicine, especially if your child is taking other medicines that contain propylene glycol or alcohol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to give HEMANGIOL to your child<\/h2>\n\n\n\n<p>The treatment of your child should be started by a doctor who has the competence to diagnose, treat and treat hemangiomas in infants (infantile hemangiomas).<\/p>\n\n\n\n<p>Always give this medicine to your child according to the doctor&#8217;s or pharmacist&#8217;s instructions.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Never change the&nbsp;dose&nbsp;yourself&nbsp;that you give to your child.&nbsp;Each&nbsp;dose&nbsp;increase&nbsp;and each dose adjustment adjusted to your child&#8217;s weight must be made by your doctor.<\/strong><\/p>\n\n\n\n<p><strong>Dose<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dosage&nbsp;one is based on the child&#8217;s weight, see the table below.<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Week(daily&nbsp;dose&nbsp;)<\/td><td>Dos&nbsp;per intag<\/td><td>Time of ingestion<\/td><\/tr><tr><td>The first week(1 mg \/ kg \/ day)<\/td><td>0.5 mg \/ kg<\/td><td>once in the morning once in the late afternoon at least 9 hours between each intake<\/td><\/tr><tr><td>Second week(2 mg \/ kg \/ day)<\/td><td>1 mg \/ kg<\/td><\/tr><tr><td>From the third week (3 mg\/kg\/day)<\/td><td>1.5 mg \/ kg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>If necessary, you can mix the medicine with a little infant formula or age-appropriate apple juice and \/ or orange juice, and give it to your baby in a baby bottle.&nbsp;Do not mix the medicine with a full bottle of milk or juice.For children weighing up to 5 kg, you can mix&nbsp;dose&nbsp;one with a teaspoon of milk (about 5 ml).&nbsp;For children weighing more than 5 kg, a&nbsp;dose&nbsp;can&nbsp;be mixed with a tablespoon of milk or fruit juice (about 15 ml).Use&nbsp;mixture&nbsp;one within 2 hours after preparation.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to give HEMANGIOL to your child<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>HEMANGIOL should be taken by mouth (orally).<\/li><li>The medicine should be given during or immediately after breast-feeding \/ feeding.<\/li><li>Dose&nbsp;one should always be measured using the dosing syringe that comes with the bottle.<\/li><li>Give HEMANGIOL directly into your baby&#8217;s mouth using the dosing syringe provided with the bottle.<\/li><li>Feed your baby regularly to avoid prolonged fasting.<\/li><li>If your child does not eat or vomits, the&nbsp;dose&nbsp;should be&nbsp;skipped.<\/li><li>If your child spits out a&nbsp;dose&nbsp;or you are unsure if the child has ingested all the medicine, do not give another&nbsp;dose&nbsp;but wait until it is time for the next&nbsp;dose&nbsp;.<\/li><li>HEMANGIOL and food must be given by the same person to reduce the risk of low blood sugar.&nbsp;If different people are involved, good communication is very important to ensure your child&#8217;s safety.<\/li><\/ul>\n\n\n\n<p><strong>Instructions for use:<\/strong><\/p>\n\n\n\n<p><strong>Step 1. Remove the items from the box<\/strong><\/p>\n\n\n\n<p><br>The carton contains the following items that you need to give the medicine:<\/p>\n\n\n\n<p>&#8211; The glass bottle contains 120 ml propranolol&nbsp;oral&nbsp;solution<br>&#8211; A dosing syringe graduated in mg is included with this medicine<\/p>\n\n\n\n<p>Take the bottle and dosing syringe out of the carton and take the dosing syringe out of the plastic bag.<br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><strong>Step 2. Check&nbsp;dose&nbsp;one<\/strong><\/p>\n\n\n\n<p><br>Check HEMANGIOL-&nbsp;dose&nbsp;one in milligrams (mg), which is prescribed by the doctor.&nbsp;Find the number of mg on the dosing syringe.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/18c5d072-4c78-4e09-8384-92d9355527e4\" alt=\"Picture 3\" title=\"Picture 3\"\/><\/a><\/figure>\n\n\n\n<p><strong>Step 3. Open the bottle<\/strong><\/p>\n\n\n\n<p>The bottle has been fitted with a child-resistant cork.&nbsp;To open the bottle: Press down on the plastic cap and at the same time turn the cap counterclockwise (to the left).<\/p>\n\n\n\n<p>Do not shake the bottle before use.<br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><br><strong>Step 4. Insert the syringe.<\/strong><br>Insert the tip of the dosing syringe into the bottle while holding the bottle upright and push the plunger down.<\/p>\n\n\n\n<p>Do not remove the syringe adapter from the neck of the bottle.<br>Use only the dosing syringe provided with the medicine to measure and&nbsp;dose&nbsp;one.<br>Do not use a spoon or other dosage measure.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Pierre20Fabre20Pharma20Norden20AB\/Media\/Hemangiol\/Bild20420PIL.jpg\" alt=\"Picture 4\" title=\"Picture 4\"\/><\/a><\/figure>\n\n\n\n<p><strong>Step 5: Pull up&nbsp;dose&nbsp;one<br><\/strong>With the dosing syringe in place, turn the bottle upside down.<br>Pull the plunger out of the syringe up to the number of mg you need.<br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><strong>Step 6: Check for air bubbles<br><\/strong>If you see air bubbles in the syringe, hold the syringe straight up.&nbsp;Push the plunger back just enough to expel large air bubbles.&nbsp;Then the&nbsp;dose&nbsp;in the syringe is&nbsp;adjusted&nbsp;to the one prescribed by the doctor.<br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><strong>Step 7. Remove the syringe<br><\/strong>Turn the vial correctly again and remove the entire dosing syringe from the vial.&nbsp;Be careful not to push the plunger when removing the syringe.<br><br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><strong>Step 8. Close the bottle<br><\/strong>Screw the plastic cap onto the bottle by turning it clockwise (to the right).<br><br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><strong>Step 9. Give HEMANGIOL to your child<br><\/strong>Put the dosing syringe in your child&#8217;s mouth and place it on the inside of the cheek.<br>You can now slowly&nbsp;inject&nbsp;HEMANGIOL from the dosing&nbsp;syringe&nbsp;directly into the baby&#8217;s mouth.<br>Do not lay the child down immediately after receiving the medicine.<br><br><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p><strong>Step 10: Clean the syringe.<br><\/strong>Do not disassemble the dosing syringe.&nbsp;Rinse the empty dosing syringe after use in a glass of clean water:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Bring out a glass of clean water<\/li><li>Pull out the plunger<\/li><li>Spray&nbsp;the water in your sink<\/li><li><strong>Repeat this cleaning process three times.<\/strong><\/li><\/ol>\n\n\n\n<p><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130410000148#\" rel=\"noopener\"><\/a><br><br>Do not use soap or alcohol-based products for cleaning.&nbsp;Wipe the outside dry.<\/p>\n\n\n\n<p>Do not clean the dosing syringe in a sterilizer or dishwasher.<\/p>\n\n\n\n<p>Keep the bottle and dosing syringe together in the carton in a safe place where your child can not see or reach it, until the next time it is to be used.&nbsp;Discard the dosing syringe when the bottle is empty.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you give too much HEMANGIOL to your child<\/h2>\n\n\n\n<p>If you have given your child too much HEMANGIOL, contact a doctor immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to give HEMANGIOL to your child<\/h2>\n\n\n\n<p>Skip the missed&nbsp;dose&nbsp;one and do not give a double&nbsp;dose&nbsp;to compensate for a missed&nbsp;dose.&nbsp;Continue treatment at the usual frequency: one&nbsp;dose&nbsp;in the morning and one in the afternoon.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop giving HEMANGIOL to your child<\/h2>\n\n\n\n<p>You can stop giving HEMANGIOL immediately when your doctor decides to stop treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p>Be aware of important warning signs of possible&nbsp;side effects&nbsp;after&nbsp;administration&nbsp;of HEMANGIOL, such as low&nbsp;blood pressure, low heart rate, low blood sugar, and&nbsp;bronchospasm&nbsp;(difficulty breathing) after&nbsp;administration&nbsp;of HEMANGIOL;<\/p>\n\n\n\n<p>See section 2 of this leaflet.<\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(may affect more than 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bronchitis&nbsp;(&nbsp;inflammation&nbsp;of the trachea).<\/li><li>Sleep disorders (insomnia, poor sleep quality and difficulty waking up).<\/li><li>Diarrhea and vomiting.<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bronchospasm&nbsp;(difficulty breathing).<\/li><li>Bronchiolitis (&nbsp;inflammation&nbsp;of small airways with difficulty breathing and wheezing in the chest) associated with cough and fever).<\/li><li>Lowered&nbsp;blood pressure&nbsp;.<\/li><li>Decreased appetite.<\/li><li>Anxiety, nightmares, irritability.<\/li><li>Somnolence.<\/li><li>Cold arms and legs.<\/li><li>Constipation, abdominal pain.<\/li><li>Erythema&nbsp;(reddening of the skin).<\/li><li>Diaper rash.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people<\/strong>&nbsp;)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Disorders of the heart&#8217;s conduction system or heart rhythm disorders (slow or irregular heartbeat).<\/li><li>Hives&nbsp;(&nbsp;allergic reaction&nbsp;in the skin),&nbsp;alopecia&nbsp;(hair loss).<\/li><li>Lowered blood sugar levels.<\/li><li>Decreased&nbsp;white blood cell count&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>The frequency of the following&nbsp;side effects&nbsp;is unknown (frequency cannot be calculated from the available data)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Seizures due to low blood sugar (&nbsp;hypoglycaemia&nbsp;).<\/li><li>Bradycardia&nbsp;(abnormally slow heartbeat).<\/li><li>Low&nbsp;blood pressure&nbsp;.<\/li><li>Very low levels of&nbsp;white blood cells&nbsp;, which fight&nbsp;infection&nbsp;you.<\/li><li>Circulatory problems that cause toes and fingers to become numb and turn white.<\/li><li>Elevated potassium levels in the blood.<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store HEMANGIOL<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and bottle label.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store the bottle in the outer carton.&nbsp;Sensitive to light.&nbsp;Keep the bottle and the oral dosing syringe in the outer carton between each use.&nbsp;Do not freeze.<\/p>\n\n\n\n<p>After the first opening, the medicine should be used within 2 months.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is propranolol.&nbsp;Each ml contains 4.28 mg of propranolol hydrochloride corresponding to 3.75 mg of propranolol.<\/li><li>The other ingredients are hydroxyethylcellulose, sodium saccharin, strawberry flavor (contains propylene glycol), vanilla flavor (contains propylene glycol), citric acid monohydrate and purified water.&nbsp;For more information, see section 2 under \u201cHEMAGIOL contains&nbsp;sodium&nbsp;and propylene glycol\u201d.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>HEMANGIOL is a clear, colorless to pale yellow&nbsp;oral&nbsp;solution, with a fruity scent.<\/li><li>It comes in a 120-ml amber glass bottle, with child-resistant screw cap.&nbsp;Carton with 1 bottle.<\/li><li>A polypropylene dosing syringe, graded in mg propranolol, is included with each bottle.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>PIERRE FABRE DERMATOLOGY<\/p>\n\n\n\n<p>45 Place Abel Gance<\/p>\n\n\n\n<p>92100 BOULOGNE<\/p>\n\n\n\n<p>FRANCE<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>FARMEA<\/p>\n\n\n\n<p>10 rue Bouch\u00e9 Thomas<\/p>\n\n\n\n<p>ZAC Sud d&#8217;Orgemont<\/p>\n\n\n\n<p>49000 ANGERS<\/p>\n\n\n\n<p>FRANCE<\/p>\n\n\n\n<p>Or<\/p>\n\n\n\n<p>PIERRE FABRE MEDICAMENT PRODUCTION<\/p>\n\n\n\n<p>PROGIPHARM site, Rue du Lyc\u00e9e<\/p>\n\n\n\n<p>45500 GIEN<\/p>\n\n\n\n<p>FRANCE<\/p>\n\n\n\n<p>Contact the marketing authorization holder to find out more about this medicine.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The name of the drug is HEMANGIOL. The active substance is propranolol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2208],"tags":[13891,13886,13888,13892,13883,13887,13890,13889,13884,13885],"class_list":["post-13736","post","type-post","status-publish","format-standard","hentry","category-medicines","category-h","tag-benefits-of-hemangiol","tag-benefits-of-propranolol","tag-hemangiol","tag-hemangiol-side-effects","tag-propranolol","tag-propranolol-side-effects","tag-wat-hemangiol-is-used-for","tag-what-is-hemangiol","tag-what-is-propranolol","tag-what-propranolol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13736","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13736"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13736\/revisions"}],"predecessor-version":[{"id":15320,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13736\/revisions\/15320"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13736"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13736"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13736"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}