{"id":13679,"date":"2021-09-18T16:04:23","date_gmt":"2021-09-18T16:04:23","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13679"},"modified":"2021-11-03T11:45:24","modified_gmt":"2021-11-03T11:45:24","slug":"glyxambi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/glyxambi\/","title":{"rendered":"Glyxambi &#8211; Empagliflozin \/ linagliptin uses, dose and side effects"},"content":{"rendered":"\n<p>10 mg \/ 5 mg, 25 mg \/ 5 mg&nbsp;film-coated tablets<br>empagliflozin \/ <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/trajenta\/\">linagliptin<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Glyxambi is and what it is used for<\/h2>\n\n\n\n<p><strong>What Glyxambi is<\/strong><\/p>\n\n\n\n<p>Glyxambi contains two active substances called empagliflozin and linagliptin.<\/p>\n\n\n\n<p>Both belong to a group of drugs called &#8220;oral antidiabetics&#8221;.&nbsp;These are medicines that are taken by mouth to treat type 2&nbsp;diabetes.<\/p>\n\n\n\n<p><strong>What is type 2&nbsp;diabetes?<\/strong><\/p>\n\n\n\n<p>Type 2&nbsp;diabetes&nbsp;is a condition caused by both genes and lifestyle.&nbsp;If you have type 2&nbsp;diabetes, your&nbsp;pancreas&nbsp;may not be&nbsp;producing&nbsp;enough&nbsp;insulin&nbsp;to control the level of glucose in your blood, and your body will not be able to use its own&nbsp;insulin&nbsp;effectively.&nbsp;This causes high blood sugar levels which can lead to medical problems such as heart disease, kidney disease, blindness, and poor circulation in the arms and legs.<\/p>\n\n\n\n<p><strong>How Glyxambi works<\/strong><\/p>\n\n\n\n<p>Empagliflozin belongs to a class of drugs called&nbsp;sodium-glucose&nbsp;-kotransport\u00f6r 2 (SGLT2) inhibitors.&nbsp;It works by blocking the SGLT2\u2011&nbsp;protein&nbsp;in the kidneys.&nbsp;This causes blood sugar (&nbsp;glucose&nbsp;) to be removed through the urine.<\/p>\n\n\n\n<p>Linagliptin works in a different way, namely by enabling the pancreas to make more&nbsp;insulin&nbsp;to lower blood glucose levels.&nbsp;It does this by blocking a&nbsp;protein&nbsp;called DPP \u2011 4.<\/p>\n\n\n\n<p>In this way, Glyxambi reduces the amount of sugar in the blood.<\/p>\n\n\n\n<p><strong>What Glyxambi is used for<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Glyxambi is co-administered with&nbsp;metformin&nbsp;and \/ or sulphonylurea (SU) to treat type 2&nbsp;diabetes&nbsp;in adult patients aged 18 years and older whose&nbsp;diabetes&nbsp;cannot be controlled by&nbsp;metformin&nbsp;and \/ or sulphonylurea in combination with empagliflozin, or by treatment with&nbsp;metformin&nbsp;and \/ or sulphonylurea in combination with linagliptin.<\/li><li>Glyxambi can also be used as an alternative to taking both empagliflozin and linagliptin as separate tablets.&nbsp;To avoid overdose, do not continue to take empagliflozin and linagliptin tablets separately, if you are taking this medicine.<\/li><\/ul>\n\n\n\n<p>It is important that you continue to follow the diet and exercise advice recommended by your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Glyxambi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Glyxambi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to empagliflozin, linagliptin, any other SGLT2 inhibitor (eg dapagliflozin, kanagliflozin), any other DPP \u2011 4 inhibitor (eg sitagliptin, vildagliptin) or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking this medicine and during treatment:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have type 1&nbsp;diabetes&nbsp;(your body does not make&nbsp;insulin&nbsp;).&nbsp;Glyxambi should not be used to treat type 1&nbsp;diabetes&nbsp;.<\/li><li>if you experience rapid weight loss, nausea or vomiting, abdominal pain, strong thirst, rapid and deep breathing, confusion, unusual sleepiness or fatigue, a sweet breath, a sweet taste or metallic taste in the mouth or a different smell of sweat or urine.&nbsp;Contact a doctor or nearest hospital immediately as these symptoms may be signs of \u201cdiabetic ketoacidosis\u201d &#8211; a rare but serious, sometimes life-threatening,problems you can get in&nbsp;diabetes&nbsp;due to elevated levels of &#8220;ketone bodies&#8221; in urine or blood, which can be detected in tests.&nbsp;The risk of developing diabetic ketoacidosis may increase with prolonged fasting, high alcohol consumption, dehydration, a sudden decrease in insulin dose or a greater need for insulin as a result of major surgery or a serious illness.<\/li><li>if you are taking other medicines for&nbsp;diabetes&nbsp;, so-called sulphonylureas (eg glimepiride, glipizide) and \/ or use&nbsp;insulin&nbsp;.&nbsp;Your doctor may want to reduce the&nbsp;dose of&nbsp;one of these medicines when you take them with Glyxambi to prevent your blood sugar from getting too low (&nbsp;hypoglycaemia&nbsp;).<\/li><li>if you have or have had a disease of the pancreas.<\/li><li>if you have severe kidney problems.&nbsp;Your doctor may limit your daily&nbsp;dose&nbsp;or ask you to take another medicine (see also section 3, \u201cHow to take Glyxambi\u201d).<\/li><li>if you have severe liver problems.&nbsp;Your doctor may ask you to take another medicine.<\/li><li>if you may be at risk of dehydration, for example:<ul><li>if you vomit, have diarrhea or fever, or if you can not eat or drink<\/li><li>if you are taking medicines which increase urine production (&nbsp;diuretics&nbsp;) or lowers&nbsp;blood pressure&nbsp;et<\/li><li>if you are over 75 years old<\/li><\/ul>Possible signs are listed in section 4 under &#8220;dehydration&#8221;.&nbsp;Your doctor may ask you to stop taking Glyxambi until you recover to prevent you from losing too much body fluid.&nbsp;Ask what you can do to prevent dehydration.<\/li><li>if you are 75 years of age or older, do not start taking Glyxambi.<\/li><li>if blood tests have shown that you have an increase in the number of&nbsp;red blood cells&nbsp;in your blood (&nbsp;hematocrit&nbsp;) (see also section 4, \u201cPossible side effects\u201d).<\/li><\/ul>\n\n\n\n<p>Contact your doctor if you experience any of the following during treatment with Glyxambi:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you develop symptoms of&nbsp;acute&nbsp;pancreatitis&nbsp;, such as severe and persistent abdominal pain.&nbsp;Possible signs are listed in section 4, \u201cPossible side effects\u201d.&nbsp;Your doctor may need to change your treatment.<\/li><li>if you have a serious&nbsp;infection&nbsp;in the kidneys or urinary tract along with fever.&nbsp;Your doctor may ask you to stop taking Glyxambi until you have recovered.<\/li><li>If you get blisters on your skin, it could be a sign of a condition called bullous&nbsp;pemphigoid&nbsp;.&nbsp;Your doctor may tell you to stop taking Glyxambi.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor immediately if you experience a combination of symptoms such as pain, tenderness,&nbsp;redness,&nbsp;or swelling of the genitals or the area between the genitals and the rectum along with fever or general malaise.&nbsp;These symptoms can be a sign of a rare but serious and in the worst-case life-threatening&nbsp;infection&nbsp;called&nbsp;necrotizing&nbsp;fasciitis of the perineum or Fournier&#8217;s gangrene which destroys&nbsp;the tissue&nbsp;under the skin.&nbsp;Fournier&#8217;s gangrene must be treated immediately.<\/p>\n\n\n\n<p><em>Chiropody<\/em><\/p>\n\n\n\n<p>For all patients with&nbsp;diabetes, it is important to regularly check your feet and follow all other advice on foot care provided by healthcare professionals.<\/p>\n\n\n\n<p><em>Renal function<\/em><\/p>\n\n\n\n<p>Before starting treatment with Glyxambi and regularly during treatment, your doctor will check how well your kidneys are working.<\/p>\n\n\n\n<p><i>Urine glucose<\/i><\/p>\n\n\n\n<p>Urine tests will give a positive answer for sugar while you are taking this medicine, due to the way this medicine works.<\/p>\n\n\n\n<p><strong>Children and young people<\/strong><\/p>\n\n\n\n<p>This medicine is not recommended for children and adolescents under 18 years of age, as it has not been studied in these patients.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Glyxambi<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines.&nbsp;It is especially important to tell your doctor if you are taking the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>other medicines for&nbsp;diabetes&nbsp;such as&nbsp;insulin&nbsp;or a sulphonylurea.&nbsp;Your doctor may want to lower the&nbsp;dose of&nbsp;one of these other medicines to prevent your blood sugar levels from getting too low.<\/li><li>diuretics (&nbsp;diuretics&nbsp;).&nbsp;Your doctor may ask you to stop taking Glyxambi.<\/li><li>drugs that can affect the breakdown of empagliflozin or linagliptin in the body such as rifampicin (an&nbsp;antibiotic&nbsp;used to treat&nbsp;tuberculosis&nbsp;) or certain anticonvulsant drugs (such as carbamazepine, phenobarbital or&nbsp;phenytoin&nbsp;).&nbsp;The effect of Glyxambi may be weakened.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n<p>It is unknown whether Glyxambi is harmful to the unborn baby.&nbsp;As a precautionary measure, it is best to avoid the use of this medicine during pregnancy.<\/p>\n\n\n\n<p>It is not known whether the active substances in Glyxambi pass into breast milk.&nbsp;Do not use this medicine if you are breastfeeding.<\/p>\n\n\n\n<p>It is not known whether Glyxambi affects&nbsp;human&nbsp;fertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Glyxambi has little effect on the ability to drive and use machines.<\/p>\n\n\n\n<p>Taking this medicine in combination with medicines called sulphonylureas or with&nbsp;insulin&nbsp;may cause excessive blood sugar (hypoglycemia), which may cause symptoms such as tremors, sweating, and vision changes and may affect your ability to drive and use machines.&nbsp;Do not drive or use any tools or machines if you experience any of these symptoms while taking Glyxambi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Glyxambi<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>How much to take<\/strong><\/p>\n\n\n\n<p>The usual starting dose is a film-coated tablet of Glyxambi 10 mg \/ 5 mg (10 mg empagliflozin and 5 mg linagliptin) once daily.<\/p>\n\n\n\n<p>Your doctor will decide if you need to increase the&nbsp;dose of&nbsp;one to one film-coated tablet Glyxambi 25 mg \/ 5 mg (25 mg empagliflozin and 5 mg linagliptin) once daily.&nbsp;If you are already taking 25 mg empagliflozin and 5 mg linagliptin as separate tablets and you are switching to Glyxambi, you can start immediately with Glyxambi 25 mg \/ 5 mg.<\/p>\n\n\n\n<p><em>Renal impairment:<\/em><\/p>\n\n\n\n<p>Talk to your doctor if you have kidney problems.&nbsp;Your doctor may limit your&nbsp;dose&nbsp;or decide to use another medicine.<\/p>\n\n\n\n<p><em>Hepatic impairment:<\/em><\/p>\n\n\n\n<p>Talk to your doctor if you suffer from severe hepatic impairment.&nbsp;Glyxambi is not recommended in this condition and your doctor may decide to use another medicine.<\/p>\n\n\n\n<p><em>Older:<\/em><\/p>\n\n\n\n<p>There is not much experience from patients aged 75 years and older.&nbsp;Treatment with Glyxambi should not be started in patients over 75 years of age.<\/p>\n\n\n\n<p><strong>Taking this medicine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swallow the tablet whole with water.<\/li><li>You can take Glyxambi with or without food.<\/li><li>You can take the tablet at any time of the day.&nbsp;However, try to take it at the same time each day.&nbsp;This will help you remember to take it.<\/li><\/ul>\n\n\n\n<p>Your doctor may prescribe Glyxambi together with another diabetes medicine.&nbsp;Remember to take all medicines according to your doctor&#8217;s instructions to achieve the best possible results for your health.<\/p>\n\n\n\n<p>Proper diet and exercise will help your body make better use of your blood sugar.&nbsp;It is important to continue with the diet and exercise programs recommended by your doctor when taking Glyxambi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Glyxambi than you should<\/h2>\n\n\n\n<p>If you have taken too much of this medicine, talk to a doctor immediately or go to a hospital immediately.&nbsp;Take the medicine pack with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Glyxambi<\/h2>\n\n\n\n<p>What to do if you forget to take a tablet depends on how long it takes until the next dose:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If it is 12 hours or more until the next&nbsp;dose&nbsp;, take Glyxambi as soon as you remember.&nbsp;Then take your next&nbsp;dose&nbsp;at the usual time.<\/li><li>If it is less than 12 hours until the next&nbsp;dose&nbsp;, skip the missed&nbsp;dose&nbsp;.&nbsp;Then take your next&nbsp;dose&nbsp;at the usual time.<\/li><li>Do not take a double&nbsp;dose&nbsp;of this medicine to make up for a forgotten&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Glyxambi<\/h2>\n\n\n\n<p>Do not stop taking this medicine without first discussing it with your doctor.&nbsp;Your blood sugar levels may rise when you stop taking Glyxambi.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact your doctor or nearest hospital immediately if you get any of the following side effects:<\/strong><\/p>\n\n\n\n<p><strong>Rare diabetic ketoacidosis (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<p>These are the signs of diabetic ketoacidosis (see also section 2, \u201cWarnings and precautions\u201d):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased levels of &#8220;ketone bodies&#8221; in the urine or blood<\/li><li>rapid weight loss<\/li><li>nausea or vomiting<\/li><li>abdominal pain<\/li><li>strong thirst<\/li><li>rapid and deep breathing<\/li><li>confusion<\/li><li>unusual drowsiness or fatigue<\/li><li>a sweet smell on the breath, a sweet taste or metallic taste in the mouth or a different smell on sweat or urine.<\/li><\/ul>\n\n\n\n<p>This can occur regardless of blood sugar levels.&nbsp;Your doctor may decide to temporarily or permanently discontinue your treatment with this medicine.<\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you notice any of the following side effects:<\/strong><\/p>\n\n\n\n<p><em>Allergic reactions, uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<p>This medicine can cause allergic reactions that can be serious, including hives (&nbsp;urticaria&nbsp;) and swelling of the face, lips, tongue, and throat which may cause difficulty breathing or swallowing (&nbsp;angioedema&nbsp;).<\/p>\n\n\n\n<p><em>Inflammation&nbsp;of the pancreas (&nbsp;pancreatitis&nbsp;), less common<\/em><\/p>\n\n\n\n<p>This drug can cause&nbsp;pancreatitis, which usually manifests as persistent, severe abdominal pain that can radiate to the back and is often accompanied by nausea or vomiting.&nbsp;Your doctor may need to change your treatment.<\/p>\n\n\n\n<p><em>Low blood sugar (hypoglycemia), common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<p>If you take Glyxambi with another medicine that may cause low blood sugar, such as sulphonylurea or&nbsp;insulin, you may have hypoglycaemia (hypoglycemia).&nbsp;Signs of too low blood sugar can be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>tremors, sweating, strong feeling of anxiety or confusion, rapid heartbeat<\/li><li>excessive hunger, headache<\/li><\/ul>\n\n\n\n<p>Your doctor will tell you how to treat low blood sugar levels and what to do if you get any of the above signs.&nbsp;If you have symptoms of low blood sugar;&nbsp;eat grape sugar tablets, a sugary snack, or drink fruit juice.&nbsp;If possible, measure your blood sugar and rest.<\/p>\n\n\n\n<p><em>Urinary tract infection, common<\/em><\/p>\n\n\n\n<p>Signs of urinary tract infection are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a burning sensation when urinating<\/li><li>cloudy urine<\/li><li>pain in the pelvis, or in the middle of the back (when the kidneys are infected)<\/li><\/ul>\n\n\n\n<p>Urinary incontinence or the need to urinate more often may be due to the way this medicine works, but may also be a sign of a urinary tract infection.&nbsp;If you notice an increase in these symptoms, contact your doctor.<\/p>\n\n\n\n<p><em>Loss of body fluid (dehydration), less common<\/em><\/p>\n\n\n\n<p>Signs of dehydration are not specific, but may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>unusual thirst<\/li><li>dizziness or dizziness when standing up<\/li><li>fainting spells or unconsciousness<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;when taking Glyxambi:<\/strong><\/p>\n\n\n\n<p><strong>Usual<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fungal infection, e.g.&nbsp;candida&nbsp;, around the genitals<\/li><li>inflammation&nbsp;of the nose or throat (&nbsp;nasopharyngitis&nbsp;)<\/li><li>cough<\/li><li>greater amount of urine than usual or having to urinate more often<\/li><li>itching<\/li><li>rash<\/li><li>increased levels of amylase enzyme in the blood<\/li><li>increased content of lipase enzyme in the pancreas<\/li><li>thirst<\/li><\/ul>\n\n\n\n<p><strong>Less common<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>exertion or pain when emptying the bladder<\/li><li>blood tests may show changes in blood fat levels, an increase in the amount of&nbsp;red blood cells&nbsp;(increased&nbsp;hematocrit&nbsp;) and changes linked to kidney function (decreased filtration rate and increased blood creatinine)<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sores in the mouth<\/li><\/ul>\n\n\n\n<p><strong>No known frequency (can not be calculated from the available data)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blisters on the skin (bullous&nbsp;pemphigoid&nbsp;)<\/li><li>necrotizing&nbsp;fasciitis of the perineum or Fournier&#8217;s gangrene, a severe soft tissue infection of the genitals or the area between the genitals and the rectum<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Glyxambi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Do not use this medicine if the package is damaged or shows signs of being opened earlier.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><em>Glyxambi film-coated tablets 10 mg \/ 5 mg<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are empagliflozin and linagliptin.&nbsp;Each film-coated tablet contains 10 mg empagliflozin and 5 mg linagliptin.<\/li><li>The other ingredients are:<br><em>Tablet core:<\/em>&nbsp;mannitol (E421), pregelatinized&nbsp;starch&nbsp;(maize), maize starch, copovidone, crospovidone, talc and magnesium stearate.<br><em>Film coating:<\/em>&nbsp;hypromellose, mannitol (E421), talc, titanium dioxide (E171), macrogol 6000 and yellow iron oxide (E172).<\/li><\/ul>\n\n\n\n<p><em>Glyxambi film-coated tablets 25 mg \/ 5 mg<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are empagliflozin and linagliptin.&nbsp;Each film-coated tablet contains 25 mg empagliflozin and 5 mg linagliptin.<\/li><li>The other ingredients are:<br><em>Tablet core:<\/em>&nbsp;mannitol (E421), pregelatinized&nbsp;starch&nbsp;(maize), maize starch, copovidone, crospovidone, talc and magnesium stearate.<br><em>Film coating:<\/em>&nbsp;hypromellose, mannitol (E421), talc, titanium dioxide (E171), macrogol 6000 and red iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Glyxambi 10 mg \/ 5 mg film-coated tablets (tablets) are pale yellow, rounded triangular, and smooth with a beveled edge.&nbsp;They have &#8220;10\/5&#8221; on one side and the Boehringer Ingelheim logo on the other side.&nbsp;Each side of the tablet is 8 mm long.<\/p>\n\n\n\n<p>Glyxambi 25 mg \/ 5 mg film-coated tablets (tablets) are pale pink, triangular in shape, and smooth with a beveled edge.&nbsp;They have &#8220;25\/5&#8221; on one side and the Boehringer Ingelheim logo on the other side.&nbsp;Each side of the tablet is 8 mm long.<\/p>\n\n\n\n<p>Glyxambi is available in perforated single-dose blisters of PVC \/ PVDC \/ aluminum.<\/p>\n\n\n\n<p>Pack sizes of 7 x 1, 10 x 1, 14 x 1, 28 x 1, 30 x 1, 60 x 1, 70 x 1, 90 x 1 and 100 x 1 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed in your country.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Boehringer Ingelheim International GmbH<br>Binger Str. 173<br>55216 Ingelheim am Rhein<br>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Boehringer Ingelheim Pharma GmbH &amp; Co.&nbsp;KG<br>Binger Strasse 173<br>55216 Ingelheim am Rhein<br>Germany<\/p>\n\n\n\n<p>Rottendorf Pharma GmbH<\/p>\n\n\n\n<p>Ostenfelder Strasse 51\u201161<\/p>\n\n\n\n<p>59320 Ennigerloh<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glyxambi contains two active substances called empagliflozin and linagliptin.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2207],"tags":[14130,14134,14141,14129,14131,14135,14136,14137,14142,14140,14125,14128,14133,14139,14132,14138,14126,14127],"class_list":["post-13679","post","type-post","status-publish","format-standard","hentry","category-medicines","category-g","tag-linagliptin-side-effects","tag-benefits-of-empagliflozin","tag-benefits-of-glyxambi","tag-benefits-of-linagliptin","tag-empagliflozin","tag-empagliflozin-side-effects","tag-empagliflozin-tablet","tag-glyxambi","tag-glyxambi-side-effects","tag-glyxambi-tablet","tag-linagliptin","tag-linagliptin-tablet","tag-what-empagliflozin-is-used-for","tag-what-glyxambi-is-used-for","tag-what-is-empagliflozin","tag-what-is-glyxambi","tag-what-is-linagliptin","tag-what-linagliptin-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13679"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13679\/revisions"}],"predecessor-version":[{"id":15398,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13679\/revisions\/15398"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13679"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13679"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}