{"id":13476,"date":"2021-09-17T12:41:12","date_gmt":"2021-09-17T12:41:12","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13476"},"modified":"2021-11-05T11:52:03","modified_gmt":"2021-11-05T11:52:03","slug":"glucos-fresenius-kabi-50-mg-ml-buffered","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/glucos-fresenius-kabi-50-mg-ml-buffered\/","title":{"rendered":"Glucose Fresenius Kabi 50 mg\/ml buffered | Sodium chloride, sodium acetate trihydrate | uses, dose and side effects"},"content":{"rendered":"\n<p>infusion&nbsp;solution,&nbsp;glucose&nbsp;solution, sodium chloride, sodium acetate trihydrate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Glucos Fresenius Kabi 50 mg \/ ml buffered is and what it is used for<\/h2>\n\n\n\n<p>Glucose Fresenius Kabi 50 mg\/ml buffered contains&nbsp;electrolytes&nbsp;(salts) and&nbsp;glucose&nbsp;(sugar).&nbsp;It is used to treat dehydration and imbalance in electrolyte levels, and as an energy supplement in the form of&nbsp;glucose.&nbsp;Dehydration and\/or electrolyte imbalance can occur during, for example, surgery or injury.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Glucos Fresenius Kabi 50 mg \/ ml buffered<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Glucos Fresenius Kabi 50 mg \/ ml buffered<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;glucose&nbsp;, sodium chloride, sodium acetate trihydrate or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Glucos Fresenius Kabi 50 mg\/ml buffered if<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have&nbsp;diabetes<\/li><li>you have severe&nbsp;kidney failure&nbsp;in combination with&nbsp;edema&nbsp;(swelling)<\/li><li>your urine volume decreases or if you have no urine production<\/li><li>you have severe&nbsp;heart failure<\/li><li>you are severely malnourished<\/li><li>you drink large amounts of alcohol<\/li><li>you suffer from&nbsp;anorexia<\/li><li>you have vomited a lot during pregnancy<\/li><li>you get blood.&nbsp;Your doctor or nurse will make sure that blood is not supplied via the same tube as Rehydrex with glucose, as this may cause the blood to clot.<\/li><\/ul>\n\n\n\n<p>The amount of&nbsp;electrolytes in&nbsp;your blood can be checked with blood tests, especially if you need a lot of fluid quickly.<\/p>\n\n\n\n<p>Particular caution will be exercised if you have a disease or condition that can cause high levels of&nbsp;vasopressin, a&nbsp;hormone&nbsp;that regulates the body&#8217;s fluid balance.&nbsp;You may have too much&nbsp;vasopressin&nbsp;in your body e.g.&nbsp;if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have suffered from a sudden and serious illness<\/li><li>you have pain<\/li><li>you have undergone an operation<\/li><li>you have&nbsp;infection&nbsp;, burns or a brain disease<\/li><li>You have diseases that are associated with the heart, liver, kidneys or central nervous system&nbsp;<\/li><li>you are taking certain medicines.<\/li><\/ul>\n\n\n\n<p>This can increase the risk of low sodium levels in the blood which can lead to headaches, nausea, cramps, listlessness,&nbsp;coma, swelling of the brain, and death.&nbsp;Swelling in the brain increases the risk of death and brain damage.&nbsp;The following patients are at increased risk for brain swelling:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>children<\/li><li>women (especially of&nbsp;childbearing potential&nbsp;)<\/li><li>patients who have problems with fluid balance in the brain e.g.&nbsp;due to&nbsp;meningitis&nbsp;, skull bleeding or brain damage.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Glucos Fresenius Kabi 50 mg \/ ml buffered<\/h2>\n\n\n\n<p>Tell your doctor if you have recently taken or might take any other medicines if you are&nbsp;taking digitalis glycosides&nbsp;(used to treat&nbsp;heart failure&nbsp;and heart rhythm disorders).<\/p>\n\n\n\n<p>It is especially important that you tell your doctor if you are taking medicines that affect the&nbsp;hormone&nbsp;et&nbsp;vasopressin.&nbsp;Such drugs may be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diabetes medicine (chloropropamide)<\/li><li>cholesterol drugs (clofibrate)<\/li><li>epilepsy drug (carbamazepine)<\/li><li>amphetamine-like drugs<\/li><li>certain cancer drugs (vincristine, ifosfamide, cyclophosphamide)<\/li><li>selective serotonin reuptake inhibitors (used to treat depression)<\/li><li>antipsychotics<\/li><li>opioids&nbsp;(morphine-like drugs) used to treat severe pain&nbsp;<\/li><li>painkillers and&nbsp;anti-inflammatory&nbsp;drugs&nbsp;(so-called non-steroidal anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;))<\/li><li>drugs similar to or enhancing the effect of vasopressin, such as desmopressin (used to treat increased thirst and urination), terlipressin (used to treat esophageal bleeding) and&nbsp;oxytocin&nbsp;(used to initiate labor).<\/li><\/ul>\n\n\n\n<p>Other drugs that increase the risk of low levels of&nbsp;sodium&nbsp;in the blood (&nbsp;hyponatremia&nbsp;) also include&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;) in general and epilepsy drugs such as oxcarbazepine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or nurse for advice before taking this medicine.<\/p>\n\n\n\n<p>Rehydrex with glucose can be used during pregnancy and lactation.<\/p>\n\n\n\n<p>This medicine should be given with special caution to pregnant women during childbirth, especially if it is combined with&nbsp;oxytocin&nbsp;(a&nbsp;hormone&nbsp;that can be used to induce pain and control bleeding) due to the risk of low sodium levels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Glucose Fresenius Kabi 50 mg\/ml buffered has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Glucose Fresenius Kabi 50 mg \/ ml buffered contains sodium and glucose<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>70 mmol (or 1600 mg)&nbsp;sodium&nbsp;per 1000 ml.&nbsp;This should be taken into consideration for patients prescribed a low-salt diet.<\/li><li>50 g&nbsp;glucose&nbsp;per 1000 ml.&nbsp;This should be considered for patients with&nbsp;diabetes&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Glucos Fresenius Kabi 50 mg \/ ml buffered<\/h2>\n\n\n\n<p>Glucos Fresenius Kabi 50 mg\/ml buffered will be given to you by a doctor or nurse.&nbsp;It will be given to you as a drip into a vein (&nbsp;intravenous&nbsp;infusion&nbsp;) Your doctor will determine the right&nbsp;dose&nbsp;for you and when and how it should be given.&nbsp;Dosage&nbsp;one is individual and depends on your clinical condition.<\/p>\n\n\n\n<p>Before and after&nbsp;infusion&nbsp;one, the doctor will monitor the body&#8217;s fluid balance, the acid level in the blood and urine, and the electrolyte level (especially&nbsp;sodium&nbsp;) in the blood (mainly in patients who have high levels of&nbsp;vasopressin&nbsp;or who are taking medicines that increase its effects).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Glucos Fresenius Kabi 50 mg \/ ml buffered than you should<\/h2>\n\n\n\n<p>Glucos Fresenius Kabi 50 mg\/ml buffered is given by healthcare professionals, so it is unlikely that you will receive a larger&nbsp;dose&nbsp;than you should.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>An overdose can lead to&nbsp;osmotic&nbsp;diuresis&nbsp;(increased urinary excretion), elevated blood sugar levels and&nbsp;metabolic alkalosis&nbsp;(too low an acid level in the blood).<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thrombophlebitis&nbsp;(blood clot and&nbsp;inflammation&nbsp;at the injection site).<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Superhydration (too much fluid in the body), electrolyte imbalance<\/li><li>Tissue damage (due to the drug accidentally ending up outside the blood vessel).<\/li><li>Headache, nausea, cramps, listlessness and vomiting.&nbsp;This can be caused by low levels of&nbsp;sodium&nbsp;in the blood (&nbsp;hyponatremia&nbsp;).&nbsp;Low sodium levels can lead to brain damage and death due to swelling in the brain (see also \u201cWarnings and Precautions\u201d).<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Glucos Fresenius Kabi 50 mg \/ ml buffered<\/h2>\n\n\n\n<p>Instructions for storage of the medicine after opening can be found in the section intended for healthcare professionals.<\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the sachet and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not use this medicine if the solution is not clear and colorless\/yellowish or if the container is damaged.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substances are<br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><\/td><td>1 ml<\/td><td>1000 ml<\/td><\/tr><tr><td>Glucose monohydrate equivalent&nbsp;anhydrous&nbsp;glucose<\/td><td>50 mg<\/td><td>50 g<\/td><\/tr><tr><td>Sodium acetate trihydrate<\/td><td>3.4 mg<\/td><td>3.4 g<\/td><\/tr><tr><td>Sodium chloride<\/td><td>2.6 mg<\/td><td>2.6 g<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em>Electrolyte content:<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><\/td><td>1000 ml<\/td><\/tr><tr><td>Na&nbsp;<sup>+<\/sup><\/td><td>1600 mg<\/td><td>70 mmol \/ 1000 ml<\/td><\/tr><tr><td>Cl-<\/td><td>about 1600 mg<\/td><td>45 mmol \/ 1000 ml<\/td><\/tr><tr><td>CH&nbsp;<sub>3<\/sub>&nbsp;CO&nbsp;<sub>2&nbsp;<\/sub><sup>&#8211;<\/sup>&nbsp;(acetate)<\/td><td>1500 mg<\/td><td>25 mmol \/ 1000 ml<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The other ingredients are&nbsp;hydrochloric acid&nbsp;(&nbsp;pH&nbsp;adjustment) and water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Infusion&nbsp;solution<\/p>\n\n\n\n<p>Clear, colorless to yellowish,&nbsp;hypertonic,&nbsp;sterile,&nbsp;and pyrogen-free solution.&nbsp;<em>pH:<\/em>&nbsp;approx. 6.&nbsp;<em>Osmolality:<\/em>&nbsp;approx. 440 mOsm \/ kg water.&nbsp;<em>Energy value:<\/em>&nbsp;about 840 kJ (200 kcal) \/ 1000 ml,&nbsp;<em>carbohydrate content:<\/em>&nbsp;50 g \/ 1000 ml.<\/p>\n\n\n\n<p>It is available in the following containers and pack sizes:<\/p>\n\n\n\n<p><em>Plastic containers (EXCEL)<\/em><\/p>\n\n\n\n<p>12 x 500 ml<\/p>\n\n\n\n<p>9 x 1000 ml<\/p>\n\n\n\n<p><em>Freeflex (polypropylene bag)<\/em><\/p>\n\n\n\n<p>15 x 500 ml<\/p>\n\n\n\n<p>20 x 500 ml<\/p>\n\n\n\n<p>10 x 1000 ml<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Fresenius Kabi AB, Uppsala, Sweden<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong>&nbsp;<\/p>\n\n\n\n<p>Fresenius Kabi Norge AS, Halden, Norway<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glucose Fresenius Kabi 50 mg\/ml buffered contains electrolytes (salts) and glucose (sugar). It is used to treat dehydration and imbalance in electrolyte levels, and as an energy supplement in the form of glucose. Dehydration and\/or electrolyte imbalance can occur during, for example, surgery or injury.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2207],"tags":[14267,14273,11620,14264,14268,14269,14272,11616,11619,14266,14265,14270,11617,14271,11618],"class_list":["post-13476","post","type-post","status-publish","format-standard","hentry","category-medicines","category-g","tag-benefits-of-glucose-fresenius-kabi-50-mg-ml-buffered","tag-benefits-of-sodium-acetate-trihydrat","tag-benefits-of-sodium-chloride","tag-glucose-fresenius-kabi-50-mg-ml-buffered","tag-glucose-fresenius-kabi-50-mg-ml-buffered-side-effects","tag-sodium-acetate-trihydrat","tag-sodium-acetate-trihydrat-side-effects","tag-sodium-chloride","tag-sodium-chloride-side-effects","tag-what-glucose-fresenius-kabi-50-mg-ml-buffered-is-used-for","tag-what-is-glucose-fresenius-kabi-50-mg-ml-buffered","tag-what-is-sodium-acetate-trihydrat","tag-what-is-sodium-chloride","tag-what-sodium-acetate-trihydrat-is-used-for","tag-what-sodium-chloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13476","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13476"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13476\/revisions"}],"predecessor-version":[{"id":15459,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13476\/revisions\/15459"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13476"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13476"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}