{"id":13470,"date":"2021-09-17T12:37:24","date_gmt":"2021-09-17T12:37:24","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13470"},"modified":"2021-11-05T11:54:03","modified_gmt":"2021-11-05T11:54:03","slug":"glucos-fresenius-kabi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/glucos-fresenius-kabi\/","title":{"rendered":"Glucose Fresenius Kabi &#8211; Glucose uses, dose and side effects"},"content":{"rendered":"\n<p>50, 100 and 200 mg \/ mL&nbsp;infusion&nbsp;solution<br>glucose<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Glucos Fresenius Kabi is and what it is used for<\/h2>\n\n\n\n<p>Glucose Fresenius Kabi&nbsp;solution for infusion&nbsp;is a clear solution of&nbsp;glucose&nbsp;in water for&nbsp;intravenous&nbsp;infusion&nbsp;(slow&nbsp;injection&nbsp;), also called drip into a vein.<\/p>\n\n\n\n<p>Glucose Fresenius Kabi 50 and 100 mg\/ml are used when the body has lost a lot of water (&nbsp;dehydration&nbsp;).<\/p>\n\n\n\n<p>All strengths can be given when&nbsp;intravenous&nbsp;nutrition is needed, usually in combination with&nbsp;amino acid&nbsp;(&nbsp;protein&nbsp;) solutions,&nbsp;vitamins,&nbsp;and&nbsp;lipid&nbsp;(fat)&nbsp;emulsions.<\/p>\n\n\n\n<p>This leaflet covers three different strengths.&nbsp;These solutions will be collectively referred to as Glucos Fresenius Kabi in this leaflet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Glucos Fresenius Kabi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Glucos Fresenius Kabi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;glucose&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p>Or if you have one or more of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Untreated&nbsp;diabetes&nbsp;, diabetic coma.<\/li><li>Other known glucose hypersensitivity.<\/li><li>Unconsciousness due to high blood sugar (hyperosmolar&nbsp;coma&nbsp;).<\/li><li>High blood sugar (&nbsp;hyperglycaemia&nbsp;).<\/li><li>Low levels of&nbsp;potassium&nbsp;in the blood (&nbsp;hypokalaemia&nbsp;).<\/li><li>Too much acid in the body (metabolic&nbsp;acidosis&nbsp;).<\/li><li>Untreated excretion of large amounts of urine (&nbsp;<em>diabetes insipidus<\/em>&nbsp;).<\/li><li>Renal impairment without the possibility of&nbsp;haemofiltration&nbsp;or&nbsp;dialysis&nbsp;.<\/li><li>Bleeding in the brain or spine.<\/li><li>Alcohol withdrawal (&nbsp;<em>deliruim tremens<\/em>&nbsp;) if the patient is already dehydrated.<\/li><li>Acute&nbsp;state of shock and collapse.<\/li><li>Acute&nbsp;heart failure&nbsp;.<\/li><li>Fluid accumulation in the lungs (&nbsp;pulmonary edema&nbsp;).<\/li><li>Too much fluid in the body (hyperhydration).<\/li><li>Not enough fluid in the body, with low&nbsp;blood pressure&nbsp;(&nbsp;hypotonic&nbsp;dehydration&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Glucos Fresenius Kabi.<\/p>\n\n\n\n<p>Blood sugar,&nbsp;electrolytes&nbsp;(especially serum potassium and&nbsp;phosphate&nbsp;), and fluid balance should be checked regularly.<\/p>\n\n\n\n<p>Healthcare professionals will monitor you when&nbsp;infusing&nbsp;large volumes if you have too much or not enough fluid in your body, severely impaired kidney, heart, and lung function, and\/or decreased urine production.<\/p>\n\n\n\n<p>Glucose tolerance may decrease if you have impaired kidney function or&nbsp;diabetes.&nbsp;Healthcare professionals will monitor your glucose levels and&nbsp;electrolytes&nbsp;during&nbsp;administration&nbsp;if you are diabetic or have impaired kidney function.&nbsp;Your needs for&nbsp;insulin&nbsp;and\/or&nbsp;potassium&nbsp;may change.&nbsp;Your doctor will check these.<\/p>\n\n\n\n<p>If you are malnourished,&nbsp;infusion&nbsp;of carbohydrates can trigger a thiamine deficiency syndrome (&nbsp;vitamin&nbsp;B&nbsp;<sub>1<\/sub>&nbsp;).&nbsp;This is especially true if the cause of malnutrition is:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>alcohol abuse,<\/li><li>anorexia&nbsp;,<\/li><li>fasting for a long time,<\/li><li>if you are pregnant and have severe nausea and \/ or vomiting.<\/li><\/ul>\n\n\n\n<p>Your doctor may decide to give you extra&nbsp;vitamin&nbsp;B&nbsp;<sub>1<\/sub>&nbsp;before and during&nbsp;the administration of&nbsp;one of&nbsp;glucose.<\/p>\n\n\n\n<p>Use of glucose solution is not recommended if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the supply of blood to a part of the brain decreases (&nbsp;acute&nbsp;ischemic&nbsp;stroke&nbsp;) because high blood sugar has been reported to increase brain damage and impair healing.<\/li><li>you have suffered a head injury in the last 24 hours.<\/li><\/ul>\n\n\n\n<p>Blood sugar levels will be closely monitored by medical staff in case of high&nbsp;blood pressure&nbsp;in the brain.<\/p>\n\n\n\n<p>Particular caution will be exercised if you have a disease or condition that can cause high levels of&nbsp;vasopressin, a&nbsp;hormone&nbsp;that regulates the amount of fluid in your body.&nbsp;You may have too much&nbsp;vasopressin&nbsp;in your body e.g.&nbsp;if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have suffered from a sudden and serious illness<\/li><li>you have pain<\/li><li>you have undergone an operation<\/li><li>you have&nbsp;infection&nbsp;, burns or a brain disease<\/li><li>You have diseases that are associated with the heart, liver, kidneys or&nbsp;central nervous system<\/li><li>you are taking certain medicines.<\/li><\/ul>\n\n\n\n<p>This can increase the risk of low sodium levels in the blood which can cause headaches, nausea, cramps, listlessness,&nbsp;coma, swelling in the brain, and death.&nbsp;Swelling in the brain increases the risk of death and brain damage.&nbsp;The following patients are at increased risk for brain swelling:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>children<\/li><li>women (especially of&nbsp;childbearing potential&nbsp;)<\/li><li>patients who have problems with fluid balance in the brain e.g.&nbsp;due to&nbsp;meningitis&nbsp;, skull bleeding or brain damage.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Glucos Fresenius Kabi<\/h2>\n\n\n\n<p>Tell your doctor or nurse if you have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>It is especially important that you tell your doctor if you are taking medicines that affect the&nbsp;hormone&nbsp;et&nbsp;vasopressin.&nbsp;Such drugs may be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diabetes medicine (chloropropamide)<\/li><li>cholesterol drugs (clofibrate)<\/li><li>epilepsy drug (carbamazepine)<\/li><li>amphetamine-like drugs<\/li><li>certain cancer drugs (vincristine, ifosfamide, cyclophosphamide)<\/li><li>selective serotonin reuptake inhibitors (used to treat depression)<\/li><li>antipsychotics<\/li><li>opioids&nbsp;(morphine-like drugs) used to treat severe pain<\/li><li>medicines for pain and&nbsp;inflammation&nbsp;(so-called non-steroidal anti-inflammatory drugs,&nbsp;NSAIDs&nbsp;)<\/li><li>drugs similar to or enhancing the effect of vasopressin, such as desmopressin (used to treat increased thirst and urination), terlipressin (used to treat esophageal bleeding) and&nbsp;oxytocin&nbsp;(used to initiate labor).<\/li><\/ul>\n\n\n\n<p>Other drugs that also increase the risk of low sodium levels are&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;) and epilepsy drugs, such as oxcarbazepine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or nurse for advice before taking this medicine.&nbsp;Glucose&nbsp;is considered safe when used as recommended.<\/p>\n\n\n\n<p>This medicine should be given with special caution to pregnant women during childbirth, especially if it is combined with&nbsp;oxytocin&nbsp;(a&nbsp;hormone&nbsp;that can be used to induce pain and control bleeding) due to the risk of low sodium levels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Glucose Fresenius Kabi has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Glucos Fresenius Kabi<\/h2>\n\n\n\n<p>Glucos Fresenius Kabi will be given to you by a doctor or nurse.&nbsp;It will be given to you as a drip into a vein (&nbsp;intravenous&nbsp;infusion&nbsp;) or as an&nbsp;injection&nbsp;under the skin depending on the strength of Glucos Fresenius Kabi used.<\/p>\n\n\n\n<p>Your doctor will decide the right&nbsp;dose&nbsp;for you and when and how it should be given.&nbsp;Your doctor will consider your age, weight, physical condition, and what other treatments you are receiving.<\/p>\n\n\n\n<p>Before and after&nbsp;infusion&nbsp;one, the doctor will monitor the body&#8217;s fluid balance, the acid level in the blood and urine, and the electrolyte level (especially&nbsp;sodium&nbsp;) in the blood (mainly in patients who have high levels of&nbsp;vasopressin&nbsp;or who are taking medicines that increase its effects).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Glucos Fresenius Kabi than you should<\/h2>\n\n\n\n<p>Glucos Fresenius Kabi is given by healthcare professionals, so it is unlikely that you will receive a larger&nbsp;dose&nbsp;than you should.&nbsp;If you accidentally overdose, the&nbsp;administration&nbsp;one will be canceled and you will receive treatment depending on the symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p>If the dosing recommendations are exceeded,&nbsp;osmotic&nbsp;diuresis&nbsp;(increased urine production) which may lead to dehydration may occur.<\/p>\n\n\n\n<p>Other possible&nbsp;side effects&nbsp;include:<\/p>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased urine production (&nbsp;polyuria&nbsp;).<\/li><li>High blood sugar (&nbsp;hyperglycemia&nbsp;), dehydration and electrolyte imbalance, e.g.&nbsp;low levels of&nbsp;potassium&nbsp;(&nbsp;hypokalaemia&nbsp;),&nbsp;magnesium&nbsp;(&nbsp;hypomagnesaemia&nbsp;) and&nbsp;phosphate&nbsp;(&nbsp;hypophosphataemia&nbsp;) in the blood.<\/li><li>Side effects&nbsp;are related to administration techniques including fever,&nbsp;injection site&nbsp;infection&nbsp;, local pain or reaction, venous irritation,&nbsp;inflammation&nbsp;of the vein where the solution is given (&nbsp;venous thrombosis&nbsp;or&nbsp;phlebitis&nbsp;), accidental&nbsp;administration&nbsp;of the solution outside the vein (extravasation, which may damage&nbsp;tissue&nbsp;) or too much fluid in the body (&nbsp;hypervolemia&nbsp;) and fluid retention (&nbsp;edema&nbsp;) caused by overdose.<\/li><li>Headache, nausea, cramps, listlessness and vomiting.&nbsp;This can be caused by low levels of&nbsp;sodium&nbsp;in the blood (&nbsp;hyponatremia&nbsp;).&nbsp;Low sodium levels can lead to brain damage and death due to swelling in the brain (see also \u201cWarnings and Precautions\u201d).<\/li><\/ul>\n\n\n\n<p>High blood sugar (hyperglycemia),&nbsp;urinary&nbsp;glucose&nbsp;(&nbsp;glucosuria&nbsp;), and fluid in the lungs (&nbsp;pulmonary edema&nbsp;) may occur if the solution is administered too quickly.<\/p>\n\n\n\n<p>You can be monitored by healthcare professionals during treatment.&nbsp;If any side effects get worse, your doctor or nurse will help you.&nbsp;If&nbsp;side effects&nbsp;are of concern to you, talk to a doctor or nurse.<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Glucos Fresenius Kabi<\/h2>\n\n\n\n<p><em>Freeflex&nbsp;infusion&nbsp;bag<\/em><\/p>\n\n\n\n<p>50 mg \/ ml: Do not store above 25 \u00b0 C<\/p>\n\n\n\n<p>100 mg \/ ml: No special precautions for storage.<\/p>\n\n\n\n<p>200 mg \/ ml: No special storage instructions.<\/p>\n\n\n\n<p><em>Kabipac&nbsp;infusion&nbsp;bottle<\/em><\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the sachet and carton after EXP.<\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not use this medicine if you see visible particles or if the container is damaged.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;glucose&nbsp;50 mg \/ ml, 100 mg \/ ml or 200 mg \/ ml (as glucose monohydrate).<\/li><li>The other ingredients are&nbsp;hydrochloric acid&nbsp;(&nbsp;pH&nbsp;adjustment, only 50 mg \/ ml and 100 mg \/ ml), sodium hydroxide (&nbsp;pH&nbsp;adjustment, only 50 mg \/ ml and 100 mg \/ ml), water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Glucos Fresenius Kabi 50 mg\/ml and 100 mg\/ml are clear, colorless, and sterile solutions without&nbsp;electrolytes&nbsp;and visible particles.<\/p>\n\n\n\n<p>50 mg \/ ml is&nbsp;isotonic&nbsp;, 100 mg \/ ml is&nbsp;hypertonic&nbsp;.<\/p>\n\n\n\n<p>Glucos Fresenius Kabi 200 mg\/ml is a clear, colorless to pale yellow,&nbsp;hypertonic,&nbsp;and&nbsp;sterile&nbsp;solution without&nbsp;electrolytes&nbsp;and visible particles.<\/p>\n\n\n\n<p>It is available in the following containers and pack sizes:<\/p>\n\n\n\n<p><em><strong>Glucos Fresenius Kabi 50 mg \/ ml<\/strong><\/em><\/p>\n\n\n\n<p><em>Freeflex (polypropylene bag) with injection port for needle, alternatively Freeflex + with injection port for luer cap:<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>40 x 50 ml<\/td><td>40 x 100 ml<\/td><td>20 x 250 ml<\/td><td>15 x 500 ml<\/td><td>10 x 1000 ml<\/td><\/tr><tr><td>60 x 50 ml<\/td><td>50 x 100 ml<\/td><td>30 x 250 ml<\/td><td>20 x 500 ml<\/td><td><\/td><\/tr><tr><td>65 x 50 ml<\/td><td>55 x 100 ml<\/td><td>35 x 250 ml<\/td><td><\/td><td><\/td><\/tr><tr><td>70 x 50 ml<\/td><td>60 x 100 ml<\/td><td>40 x 250 ml<\/td><td><\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em>KabiPac (polyethylene bottle):<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>10 x 100 ml<\/td><td>10 x 250 ml<\/td><td>10 x 500 ml<\/td><td>10 x 1000 ml<\/td><\/tr><tr><td>40 x 100 ml<\/td><td>20 x 250 ml<\/td><td>20 x 500 ml<\/td><td><\/td><\/tr><tr><td><\/td><td>30 x 250 ml<\/td><td>30 x 500 ml<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em><strong>Glucos Fresenius Kabi 100 mg \/ ml<\/strong><\/em><\/p>\n\n\n\n<p><em>Freeflex (polypropylene bag) with injection port for the <\/em>needle, alternatively Freeflex + with injection port for Luer<em> cap:<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>15 x 500 ml<\/td><td>10 x 1000 ml<\/td><\/tr><tr><td>20 x 500 ml<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em>KabiPac (polyethylene bottle):<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>10 x 100 ml<\/td><td>10 x 250 ml<\/td><td>10 x 500 ml<\/td><td>10 x 1000 ml<\/td><\/tr><tr><td>40 x 100 ml<\/td><td>20 x 250 ml<\/td><td>20 x 500 ml<\/td><td><\/td><\/tr><tr><td><\/td><td>30 x 250 ml<\/td><td>30 x 500 ml<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em><strong>Glucos Fresenius Kabi 200 mg \/ ml<\/strong><\/em><\/p>\n\n\n\n<p><em>Freeflex (polypropylene bag) with injection port for the needle:<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>15 x 500 ml<\/td><td>10 x 1000 ml<\/td><\/tr><tr><td>20 x 500 ml<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Fresenius Kabi AB, Uppsala,<\/p>\n\n\n\n<p><strong>Manufacturer&nbsp;<\/strong><\/p>\n\n\n\n<p>Fresenius Kabi Norge AS, Halden, Norway or<\/p>\n\n\n\n<p>Fresenius Kabi Deutschland GmbH, Friedberg, Germany or<\/p>\n\n\n\n<p>Fresenius Kabi France, Louviers Cedex, France or<\/p>\n\n\n\n<p>Fresenius Kabi Polska Sp.&nbsp;z oo, Kutno, Poland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glucose Fresenius Kabi solution for infusion is a clear solution of glucose in water for intravenous infusion (slow injection ), also called drip into a vein.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2207],"tags":[14205,14212,14201,14207,14211,14206,14209,14203,14202,14208],"class_list":["post-13470","post","type-post","status-publish","format-standard","hentry","category-medicines","category-g","tag-benefits-of-glucose","tag-benefits-of-glucose-fresenius-kabi","tag-glucose","tag-glucose-fresenius-kabi","tag-glucose-fresenius-kabi-side-effects","tag-glucose-side-effects","tag-what-glucose-fresenius-kabi-is-used-for","tag-what-glucose-is-used-for","tag-what-is-glucose","tag-what-is-glucose-fresenius-kabi"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13470"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13470\/revisions"}],"predecessor-version":[{"id":15462,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13470\/revisions\/15462"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13470"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13470"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}