{"id":13450,"date":"2021-09-17T11:38:40","date_gmt":"2021-09-17T11:38:40","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13450"},"modified":"2021-11-05T11:57:02","modified_gmt":"2021-11-05T11:57:02","slug":"glucobay","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/glucobay\/","title":{"rendered":"Glucobay &#8211; Acarbose uses, dose and side effects"},"content":{"rendered":"\n<p>50 mg, 100 mg&nbsp;tablets, acarbose<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. WHAT GLUCOBAY IS AND WHAT IT IS USED FOR<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance of the drug:<\/h2>\n\n\n\n<p>Agents for&nbsp;diabetes&nbsp;(blood sugar lowering).&nbsp;Glucobay acts in the gut by delaying the uptake of&nbsp;glucose&nbsp;into the bloodstream.&nbsp;Glucobay is used in non-insulin-requiring&nbsp;diabetes mellitus&nbsp;(so-called age-related diabetes or type 2&nbsp;diabetes&nbsp;) where diet alone does not give satisfactory results.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. WHAT YOU NEED TO KNOW BEFORE USING GLUCOBAY<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Glucobay<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to acarbose or any of the other ingredients of this medicine (listed in section 6),<\/li><li>if you have a&nbsp;chronic&nbsp;intestinal disease, intestinal ulcer,&nbsp;inflammatory&nbsp;bowel disease or intestinal obstruction or risk of intestinal obstruction<\/li><li>if you have impaired liver function<\/li><li>if you have&nbsp;kidney failure<\/li><li>if you are in a condition that can be aggravated by increased gas formation in the intestine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Glucobay has a hypoglycaemic effect but does not cause&nbsp;hypoglycaemia&nbsp;(abnormally low blood sugar).&nbsp;However, concomitant treatment with Glucobay and&nbsp;insulin&nbsp;or blood glucose-lowering tablets (eg sulphonylureas,&nbsp;metformin&nbsp;) may cause&nbsp;hypoglycaemia&nbsp;(abnormally low blood sugar).&nbsp;In such cases, take pure&nbsp;glucose&nbsp;(glucose tablets) and no sugar.&nbsp;In rare cases, hypoglycaemic&nbsp;coma&nbsp;may occur.<\/p>\n\n\n\n<p><strong>Other drugs and Glucobay<\/strong><\/p>\n\n\n\n<p>The treatment effect can be affected if Glucobay and digestive enzyme or cholestyramine (anti-high blood fats) are taken at the same time.&nbsp;Acarbose can affect the effect of&nbsp;digoxin&nbsp;(a heart medicine) with concomitant treatment.&nbsp;Therefore, consult a physician before concomitantly using other medications.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Glucobay with food and drink<\/h2>\n\n\n\n<p>It is important to continue with the recommended dietary advice when treating with Glucobay tablets.&nbsp;Treatment with Glucobay should not be stopped without consulting a doctor as it may lead to an increase in blood sugar.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Limited use experience.&nbsp;Glucobay should not be used during pregnancy.&nbsp;Talk to your doctor about other treatments during pregnancy.<\/p>\n\n\n\n<p>Glucobay should not be used during breastfeeding.&nbsp;Therefore consult a doctor before use during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>There is no evidence that Glucobay affects the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. HOW TO USE GLUCOBAY<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Dosage instructions<\/h2>\n\n\n\n<p>The dose&nbsp;should be determined by a doctor, who will tailor it individually for you.&nbsp;You should wait for the effect of dietary treatment before starting Glucobay.&nbsp;Glucobay tablets are swallowed whole with liquid just before meals or chewed with food at the beginning of a meal.<\/p>\n\n\n\n<p>You should start with a low&nbsp;dose&nbsp;which is then slowly increased to reduce any bowel side effects.<\/p>\n\n\n\n<p>The usual dosing schedule for adults can be:<br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>&nbsp;<\/td><td><strong>Breakfast<\/strong><\/td><td><strong>Lunch<\/strong><\/td><td><strong>Dinner<\/strong><\/td><\/tr><tr><td><strong>Week 1-3<\/strong><\/td><td>&#8211;<\/td><td>&#8211;<\/td><td>50 mg<\/td><\/tr><tr><td><strong>Week 4-6<\/strong><\/td><td>50 mg<\/td><td>&#8211;<\/td><td>50 mg<\/td><\/tr><tr><td><strong>Week 7-9<\/strong><\/td><td>50 mg<\/td><td>50 mg<\/td><td>50 mg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Continue treatment with 50 mg x 3 for a total of 4-6 weeks.&nbsp;Depending on the blood glucose response, the&nbsp;dose&nbsp;may&nbsp;then be increased according to the following dosing schedule.<br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>&nbsp;<\/td><td><strong>Breakfast<\/strong><\/td><td><strong>Lunch<\/strong><\/td><td><strong>Dinner<\/strong><\/td><\/tr><tr><td><strong>Week 1-3<\/strong><\/td><td>50 mg<\/td><td>50 mg<\/td><td>100 mg<\/td><\/tr><tr><td><strong>Week 4-6<\/strong><\/td><td>100 mg<\/td><td>50 mg<\/td><td>100 mg<\/td><\/tr><tr><td><strong>Week 7-9<\/strong><\/td><td>100 mg<\/td><td>100 mg<\/td><td>100 mg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The usual maintenance dose is 100 mg 3 times daily.<\/p>\n\n\n\n<p>The safety and efficacy of Glucobay in children and adolescents below 18 years of age have not yet been established.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Glucobay than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<p>If you take more&nbsp;dose&nbsp;you should avoid carbohydrate-containing food and drink for about 4-6 hours after taking the tablet, to avoid risk of flatulence, bloating and diarrhea.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p>Very common: (affects more than 1 patient in 10)<\/p>\n\n\n\n<p>weather voltage.<\/p>\n\n\n\n<p>Common: (less than 1 in 10 patients but more than 1 in 100 users)<\/p>\n\n\n\n<p>diarrhea, stomach \/ abdominal pain.<\/p>\n\n\n\n<p>Uncommon: (less than 1 in 100 patients but more than 1 in 1000 patients)<\/p>\n\n\n\n<p>nausea, vomiting, acid regurgitation.<\/p>\n\n\n\n<p>Rare: (less than 1 in 1,000 patients but more than 1 in 10,000)<\/p>\n\n\n\n<p>swelling,&nbsp;edema&nbsp;, jaundice.<\/p>\n\n\n\n<p>No known frequency: (can not be calculated from the available data)<\/p>\n\n\n\n<p>decreased&nbsp;platelet count&nbsp;(&nbsp;platelets&nbsp;), allergic reactions with symptoms such as skin rash and&nbsp;hives, pneumatosis cystoides intestinalis (an intestinal disease with gas-filled blisters in the intestinal mucosa),&nbsp;acute&nbsp;generalized exanthematous&nbsp;pustulosis&nbsp;(skin reaction with widespread redness and blisters)<\/p>\n\n\n\n<p>In patients receiving the usual&nbsp;dose&nbsp;(50-100 mg 3 times daily), abnormal liver function values \u200b\u200bhave been observed in rare cases.&nbsp;Values \u200b\u200bmay return to normal levels during ongoing Glucobay treatment.&nbsp;In isolated cases, more severe liver effects with or without jaundice have occurred.&nbsp;In these cases, Glucobay treatment should be stopped immediately.&nbsp;Your doctor may&nbsp;prescribe&nbsp;blood tests regularly during the first year of treatment.&nbsp;This is done in order to be able to rule out liver effects at an early stage.<\/p>\n\n\n\n<p>Following the launch, cases of liver disease, abnormal liver function and liver damage have been reported.&nbsp;Isolated cases of liver disease&nbsp;fulminant&nbsp;hepatitis&nbsp;with fatal outcome have also been reported, mainly from Japan.<\/p>\n\n\n\n<p>If you do not follow a strict diabetic diet, intestinal symptoms may worsen.&nbsp;This is especially true when consuming sugar or sugary foods due to the increase in carbohydrate fermentation in the intestine.&nbsp;In isolated, extremely rare cases, bowel movements may occur.<\/p>\n\n\n\n<p>If any of the&nbsp;side effects&nbsp;gets serious, or if you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor or pharmacist.<\/p>\n\n\n\n<p><em>Reporting of&nbsp;side effects&nbsp;ar<\/em><\/p>\n\n\n\n<p>If you get&nbsp;any side effects&nbsp;, talk to your doctor, pharmacist or nurse.&nbsp;This also applies to&nbsp;side effects&nbsp;that are not mentioned in this information.&nbsp;You can also report&nbsp;side effects&nbsp;directly (see details below).&nbsp;By reporting&nbsp;side effects&nbsp;, you can help increase drug safety information.<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>751 03 Uppsala<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. HOW TO STORE GLUCOBAY<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. CONTENTS OF THE PACKAGING AND OTHER INFORMATION<\/h2>\n\n\n\n<p><strong>Content declaration<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is acarbose.<\/li><li>The other ingredients are microcrystalline cellulose,&nbsp;colloidal&nbsp;anhydrous silica, magnesium stearate, corn starch.<\/li><\/ul>\n\n\n\n<p><strong>What the medicine looks like and contents of the pack<\/strong><\/p>\n\n\n\n<p>Tablet 50 mg: White to off-white, round tablet with notch, \u00d8 7 mm, marked with Bavarian cross and G50.<\/p>\n\n\n\n<p>The breaker is not for dividing the tablet into two equal parts, but only for easier swallowing.<\/p>\n\n\n\n<p>Tablets in blisters: 30 pcs, 120 pcs.<\/p>\n\n\n\n<p>Tablet 100 mg: White to off-white, oblong tablet with a notch, 13 mm in length, marked G100.<\/p>\n\n\n\n<p>The tablet can be divided into two equal parts.<\/p>\n\n\n\n<p>Tablets in blisters: 120 pcs.<\/p>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Bayer AB<\/p>\n\n\n\n<p>Box 606<\/p>\n\n\n\n<p>SE-169 26 Solna<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Bayer AG<\/p>\n\n\n\n<p>51368 Leverkusen<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Agents for diabetes (blood sugar lowering). Glucobay acts in the gut by delaying the uptake of glucose into the bloodstream. Glucobay is used in non-insulin-requiring diabetes mellitus (so-called age-related diabetes or type 2 diabetes ) where diet alone does not give satisfactory results.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2207],"tags":[14324,14329,14327,14328,14334,14330,14335,14333,14326,14332,14325,14331],"class_list":["post-13450","post","type-post","status-publish","format-standard","hentry","category-medicines","category-g","tag-acarbose","tag-acarbose-side-effect","tag-acarbose-tablet","tag-benefits-of-acarbose","tag-benefits-of-glucobay","tag-glucobay","tag-glucobay-side-effects","tag-glucobay-tablet","tag-what-acarbose-is-used-for","tag-what-glucobay-is-used-for","tag-what-is-acarbose","tag-what-is-glucobay"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13450","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13450"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13450\/revisions"}],"predecessor-version":[{"id":15470,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13450\/revisions\/15470"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13450"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13450"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13450"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}