adefovir dipivoxil<\/strong><\/li><\/ul>\n\n\n\n\u2192 <\/strong> Contact your<\/strong> doctor if you are taking any of these medicines.<\/p>\n\n\n\nOther types of medicines:<\/strong><\/p>\n\n\n\nTalk to your doctor if you are taking:<\/p>\n\n\n\n
- antifungals ,<\/strong> used to treat fungal infections, such as:- ketoconazole , itraconazole, voriconazole, posaconazole and fluconazole<\/li><\/ul>\n\n\n\n
- antibiotics ,<\/strong> used to treat bacterial infections including tuberculosis , which contain:rifabutin, clarithromycin and telithromycin<\/li>
- antidepressants,<\/strong> used to treat depression:- medicines containing trazodone or escitalopram<\/li>
- sedatives and hypnotics ,<\/strong> used to treat anxiety:buspirone, chlorazepate, diazepam , estazolam, flurazepam, zolpidem and lorazepam<\/li>
- immunosuppressive,<\/strong> used to control the body’s immune system after a transplant, e.g .:ciclosporin, sirolimus and tacrolimus<\/li>
- Corticosteroids are,<\/strong> including:- betamethasone, budesonide, fluticasone , mometasone, prednisone, triamquinoloneThese medicines are used to treat allergies , asthma , inflammatory bowel diseases, inflammation of the eyes, joints and muscles and other inflammatory conditions. If there are no alternatives, the medicine should be used only after a doctor’s evaluation and under the close supervision of your doctor for side effects of corticosteroids .<\/li>
- drugs used to treat diabetes<\/strong> :- metformin<\/li>
- birth control pills ,<\/strong> used to prevent pregnancy<\/li>
- drugs for erectile dysfunction ,<\/strong> used to treat impotence , e.g .:- sildenafil, tadalafil and vardenafil<\/li>
- cardiac drugs,<\/strong> eg:- digoxin , disopyramide , flecainide , lidocaine (injectable), mexiletine, propafenone , metoprolol , timolol , amlodipine, diltiazem , felodipine, nicardipine, nifedipine and verapamil<\/li>
- drugs used to treat pulmonary arterial hypertension<\/strong> :- bosentan and tadalafil<\/li>
- anticoagulants ,<\/strong> are used to prevent and treat blood clots, eg:apixaban, edoxaban, rivaroxaban and warfarin<\/li>
- bronchodilators ,<\/strong> used to treat asthma and other lung problems:- salmeterol<\/li>
- cholesterol-lowering drugs,<\/strong> eg:atorvastatin and pitavastatin<\/li>
- drugs used to treat gout<\/strong> :- colchicine<\/li><\/ul>\n\n\n\n
- antiplatelet drugs<\/strong> , used to reduce the risk of blood clots, such as:<\/li><\/ul>\n\n\n\n
-klopidogrel<\/p>\n\n\n\n
- medicines or supplements containing minerals (such as magnesium , aluminum, calcium , iron, zinc)<\/strong> , eg:<\/li><\/ul>\n\n\n\n
-mineral supplements, vitamins (including multivitamins), antacids (medicines for acid stomachs) and laxatives .<\/p>\n\n\n\n
\u2192 If you are taking medicines, supplements, antacids or laxatives that contain minerals (such as magnesium , aluminum, calcium , iron, zinc)<\/strong> , take them at least 4 hours before or at least 4 hours after Genvoya.<\/p>\n\n\n\n\u2192 <\/strong>Tell your doctor if you are taking any of these or other medicines. <\/strong>You should not stop treatment without talking to your doctor.<\/p>\n\n\n\nPregnancy and breastfeeding<\/h2>\n\n\n\n- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/li>
- Tell your doctor immediately if you are pregnant, think you may be pregnant or are planning to have a baby. <\/strong>Pregnant women should not take Genvoya. The amount of this drug in the blood may decrease during pregnancy, which may cause it to stop working properly.<\/li>
- Use <\/strong>an effective method of contraception<\/strong> while taking Genvoya.<\/li>
- Do not breast-feed during treatment with Genvoya. <\/strong>This is because some of the active substances in this medicine pass into breast milk. To avoid transmitting HIV to your baby through breast milk, do not breast-feed your baby.<\/li><\/ul>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Genvoya can cause dizziness. Do not drive or use bicycles or use tools or machines if you feel dizzy while taking Genvoya.<\/p>\n\n\n\n
Genvoya contains <\/strong>sodium<\/strong><\/p>\n\n\n\nThis medicine contains less than 1 mmol sodium (23 mg) per tablet, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
Genvoya contains <\/strong>lactose<\/strong><\/p>\n\n\n\nIf you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
\u2192<\/strong> If any of these apply to you, talk to your doctor before taking Genvoya.<\/strong><\/p>\n\n\n\n3. How to take Genvoya<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
The recommended dose is:<\/strong><\/p>\n\n\n\nAdults:<\/strong> one tablet a day with food<\/p>\n\n\n\nAdolescents and children aged 6 years and older, weighing at least 25 kg:<\/strong> one tablet a day with food.<\/p>\n\n\n\nDue to the bitter taste, it is recommended not to chew or crush the tablet.<\/p>\n\n\n\n
If you have difficulty swallowing the tablet whole, you can divide it in half. Take both halves of the tablet, one at a time, to get the full dose one. Do not save the split tablet.<\/p>\n\n\n\n
Always take the dose prescribed<\/strong> by your <\/strong>doctor<\/strong> to ensure that the medicine is effective and to reduce the risk of developing resistance to treatment. Do not change the dose unless your doctor tells you to.<\/p>\n\n\n\nDo not take antacids or multivitamins at the same time<\/strong> as Genvoya. If you are taking medicines, supplements<\/strong> , antacids or laxatives that contain minerals (such as magnesium , aluminum, calcium , iron, zinc),<\/strong> take them at least 4 hours before or at least 4 hours after Genvoya.<\/p>\n\n\n\nIf you are on dialysis<\/strong> , you should take your daily dose of Genvoya after dialysis has been completed.<\/p>\n\n\n\nIf you take more Genvoya than you should<\/h2>\n\n\n\n
If you accidentally take more than the prescribed dose of Genvoya the risk of side effects is with this drug increase (see section 4, Possible side effect s<\/em> ).<\/p>\n\n\n\nContact your doctor or nearest emergency department immediately for advice. Save the jar so you can easily describe what you have taken.<\/p>\n\n\n\n
If you forget to take Genvoya<\/h2>\n\n\n\n
It is important that you do not miss a dose of Genvoya.<\/p>\n\n\n\n
If you miss a dose:<\/p>\n\n\n\n
- If you notice it within 18 hours<\/strong> after the time you usually take Genvoya, you must take the tablet as soon as possible. The tablet must always be taken with food. Then take the next dose as usual.<\/li>
- If you notice it 18 hours or more<\/strong> after the time you usually take Genvoya, do not take the missed dose . Wait and take the next dose of food at its regular time.<\/li><\/ul>\n\n\n\n
If you vomit within less than 1 hour after a dose of Genvoya,<\/strong> take a new tablet of food.<\/p>\n\n\n\nDo not stop taking Genvoya<\/h2>\n\n\n\n
Do not stop taking Genvoya without talking to your doctor<\/strong> . If you stop taking Genvoya, it may seriously affect the effect of future treatment. If for any reason you stop taking Genvoya, talk to your doctor before taking Genvoya tablets again.<\/p>\n\n\n\nWhen your Genvoya supply starts to run low<\/strong> , get more from your<\/strong> doctor or pharmacist. This is very important because the amount of virus can start to increase even if you only stop taking the medicine for a short time. The disease can then become more difficult to treat.<\/p>\n\n\n\nIf you have both HIV – infection and hepatitis B,<\/strong> it is especially important not to stop Genvoya treatment without first talking to your doctor. You may need to submit blood samples for several months after stopping treatment. In some patients with advanced liver disease or cirrhosis , discontinuation of treatment is not recommended, as this may lead to worsening of hepatitis A, which may be life-threatening.<\/p>\n\n\n\n\u2192 <\/strong>Tell your doctor immediately<\/strong> about any new and unexpected symptoms that occur after stopping treatment, especially symptoms that you associate with hepatitis B infection .<\/p>\n\n\n\nIf you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects , although not everybody gets them.<\/p>\n\n\n\n
Possible serious side effects: Contact a doctor immediately<\/strong><\/p>\n\n\n\n- Signs of inflammation or infection . <\/strong>In some patients with advanced HIV – infection ( AIDS ) who have a history of opportunistic infection, you ( infection s that occur in people with weakened immune systems) may be signs and symptoms of inflammation from previous infections you occur shortly after HIV treatment is started . It is believed that these symptoms are due to the fact that the body’s immune system has been strengthened so that the body can fight infections that may have been present without giving any clear symptoms.<\/li>
- Autoimmune diseases,<\/strong> where the immune system attacks healthy body tissue, can also occur after you start taking medicines for HIV – infection . Autoimmune diseases can occur many months after starting treatment. Be observant of symptoms of infection or other symptoms such as:- muscle weaknessweakness that begins in the hands and feet and moves towards the torsopalpitations, tremors or hyperactivity.
\u2192 If you notice the side effects described above, tell your doctor immediately.<\/strong><\/li><\/ul>\n\n\n\nVery common side effects are<\/strong><\/p>\n\n\n\n( Can <\/em>occur <\/em>in more than 1 of 10 <\/em>users<\/em> )<\/p>\n\n\n\n