{"id":13365,"date":"2021-09-07T05:49:13","date_gmt":"2021-09-07T05:49:13","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13365"},"modified":"2021-11-09T10:58:39","modified_gmt":"2021-11-09T10:58:39","slug":"gefitinib-avansor","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/gefitinib-avansor\/","title":{"rendered":"Gefitinib Avansor &#8211; Gefitinib uses, dose and side effects"},"content":{"rendered":"\n<p>gefitinib&nbsp;250 mg film-coated tablet<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Gefitinib Avansor 250 mg film-coated tablets are and what they are used for<\/h2>\n\n\n\n<p>Gefitinib Avansor contains the active substance gefitinib which blocks a&nbsp;protein&nbsp;called&nbsp;epidermal&nbsp;growth&nbsp;factor&nbsp;receptor (EGFR).&nbsp;This&nbsp;protein&nbsp;is involved in the growth and spread of cancer cells.<\/p>\n\n\n\n<p>Gefitinib Avansor is used to treat adults with non-small cell lung cancer.&nbsp;This cancer is a disease in which malignant (cancerous) cells form in the lung tissue.<\/p>\n\n\n\n<p>Gefitinib contained in Gefitinib Advansor may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Gefitinib Avansor 250 mg film-coated tablets<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Gefitinib Avansor 250 mg film-coated tablets<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are&nbsp;<strong>allergic to gefitinib or any of the other ingredients<\/strong>&nbsp;of this medicine (listed in section 6, \u201cContents of contents\u201d).<\/li><li>if you&nbsp;<strong>are breast-feeding<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Gefitinib Avansor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have ever had&nbsp;<strong>other lung problems<\/strong>&nbsp;before&nbsp;.&nbsp;Some lung problems may be aggravated by treatment with Gefitinib Avansor.<\/li><li>if you have ever had&nbsp;<strong>liver problems<\/strong>&nbsp;<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Gefitinib Advance is not intended for use in children and adolescents below 18 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Gefitinib Avansor 250 mg film-coated tablets<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>In particular, tell your doctor or pharmacist if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>phenytoin<\/strong>&nbsp;or<strong>&nbsp;carbamazepine<\/strong>&nbsp;(for&nbsp;epilepsy&nbsp;).<\/li><li><strong>rifampicin<\/strong>&nbsp;(for&nbsp;tuberculosis&nbsp;).<\/li><li><strong>itraconazole<\/strong>&nbsp;(against fungal infections).<\/li><li><strong>barbiturate&nbsp;s<\/strong>&nbsp;(a type of medicines for sleep problems).<\/li><li>herbal medicines containing&nbsp;<strong>St. John&#8217;s wort<\/strong>&nbsp;(Hypericum perforatum, which is used for depression and anxiety).<\/li><li><strong>proton pump inhibitors<\/strong>&nbsp;,<strong>&nbsp;H2-&nbsp;antagonist&nbsp;s<\/strong>&nbsp;and<strong>&nbsp;antacids<\/strong>&nbsp;(for&nbsp;gastric ulcer&nbsp;, indigestion, heartburn and to reduce the acid in the stomach).<\/li><\/ul>\n\n\n\n<p>These medicines may affect the effect of Gefitinib Avansor.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Warfarin<\/strong>&nbsp;(a so-called&nbsp;oral&nbsp;anticoagulant to prevent blood clots).&nbsp;If you are taking a medicine containing this active substance, your doctor may need to take blood samples more often.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you, or if you are not sure, talk to your doctor or pharmacist before taking Gefitinib Avansor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant, pregnant, or breastfeeding, ask your doctor for advice before taking this medicine.<\/p>\n\n\n\n<p>It is recommended that you avoid becoming pregnant while being treated with Gefitinib Avansor as Gefitinib Avansor may harm your baby.<\/p>\n\n\n\n<p>For the safety of your baby, do not use Gefitinib Avansor if you are breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Should you feel weak while using this medicine, you should be careful when driving or using machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Gefitinib Avansor 250 mg film-coated tablets contain excipients<\/h2>\n\n\n\n<p><strong>Gefitinib Avansor&nbsp;<\/strong>&nbsp;<strong>contains&nbsp;lactose<\/strong><\/p>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Gefitinib Avansor contains croscarmellose sodium and sodium lauryl sulfate<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie&nbsp;essentially &#8216;sodium-free.&nbsp;is next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Gefitinib Avansor 250 mg film-coated tablets<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is 1 tablet (250 mg) daily.<\/li><li>Take the tablet at about the same time each day.<\/li><li>You can take the tablet with or without food.<\/li><li>Do not take antacids (to reduce the amount of acid in your stomach) 2 hours before or 1 hour after taking Gefitinib Avansor.<\/li><\/ul>\n\n\n\n<p>If you have problems swallowing the tablet, you can dissolve it in half a glass of water that does not contain carbon dioxide.&nbsp;Do not use any other liquid.&nbsp;Do not crush the tablet.&nbsp;Swirl the glass until the tablet has dissolved.&nbsp;This can take up to 20 minutes.&nbsp;Then drink the liquid immediately.&nbsp;To be sure that you have ingested all the medicine, rinse the glass very thoroughly with half a glass of water and drink from it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Gefitinib Avansor 250 mg film-coated tablets than you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Gefitinib Avansor 250 mg film-coated tablets<\/h2>\n\n\n\n<p>What to do if you forget to take a tablet depends on how much time is left until the next&nbsp;dose.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If it is 12 hours or more until the next dose: take the forgotten tablet as soon as you remember that you forgot it.&nbsp;Then take the next&nbsp;dose&nbsp;at the usual time.<\/li><li>If it is less than 12 hours until you take the next dose: skip the missed&nbsp;dose&nbsp;.&nbsp;Then take the next&nbsp;dose&nbsp;at the usual time.<\/li><\/ul>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;(two&nbsp;doses&nbsp;at the same time) to compensate for a missed&nbsp;dose.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact your doctor immediately if you get any of the following&nbsp;side effects&nbsp;&#8211; you may need immediate medical attention:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reaction&nbsp;(common) especially if the symptoms include swelling of the face, lips, tongue or throat, difficulty swallowing, hives,&nbsp;hives&nbsp;and difficulty breathing.<\/li><li>Severe shortness of breath, or sudden worsening of shortness of breath and possibly also cough and fever.&nbsp;This may mean that you have an&nbsp;inflammation&nbsp;of the lungs called &#8220;interstitial lung disease&#8221;.&nbsp;It affects approximately 1 in 100 patients taking Gefitinib Avansor and may be life-threatening.<\/li><li>Severe skin reactions (rare) that affect large areas of the body.&nbsp;Signs of this can be&nbsp;redness&nbsp;, pain, sores, blisters and flaking of the skin.&nbsp;Lips, nose, eyes and genitals can also be affected.<\/li><li>Dehydration (common) caused by prolonged or severe diarrhea, vomiting, nausea or loss of appetite.<\/li><li>Eye problems (rare) such as pain, red eyes, watery eyes, photosensitivity, changes in vision or that the&nbsp;eyelashes&nbsp;grow inwards.&nbsp;This may mean that you have a wound on the surface of the eye (cornea).<\/li><\/ul>\n\n\n\n<p><strong>Talk to your doctor as soon as possible if you get any of the following side effects:<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Loss of appetite<\/li><li>Diarrhea<\/li><li>Vomiting<\/li><li>Nausea<\/li><li>Red or sore mouth<\/li><li>Skin reactions, such as acne-like rashes that sometimes itch and include dry and \/ or cracked skin<\/li><li>Weakness<\/li><li>Elevation of the liver enzyme&nbsp;alanine aminotransferase&nbsp;in blood samples;&nbsp;if too high, your doctor may urge you to stop taking Gefitinib Advances<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dry mouth<\/li><li>Dry, red or itchy eyes<\/li><li>Red and sore eyelids<\/li><li>Nail problems<\/li><li>Hair loss<\/li><li>Fever<\/li><li>Bleeding (eg nosebleeds or blood in the urine)<\/li><li>Elevation of&nbsp;bilirubin&nbsp;and liver enzyme&nbsp;aspartate aminotransferase&nbsp;in blood tests;&nbsp;if too high, your doctor may urge you to stop taking Gefitinib Advances<\/li><li>Increased levels of&nbsp;creatinine&nbsp;in blood tests (shows how your kidneys are working),&nbsp;protein&nbsp;in the urine (seen in urine tests)<\/li><li>Cystitis&nbsp;(burning sensation when urinating and frequent, acute urges)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation&nbsp;of the pancreas.&nbsp;It is characterized by very severe pain in the upper abdomen and severe nausea and vomiting.<\/li><li>Holes (&nbsp;perforation&nbsp;are) in the gastrointestinal tract<\/li><li>Inflammation&nbsp;of the liver.&nbsp;The symptoms may be a general feeling of illness with or without any jaundice (the skin and whites of the eyes turn yellow).&nbsp;This&nbsp;side effect&nbsp;is less common, but some patients have died from it.<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation&nbsp;of the blood vessels in the skin.&nbsp;It may look like bruises or blemishes on the skin that do not fade away.<\/li><li>Hemorrhagic&nbsp;cystitis&nbsp;(burning sensation when urinating and frequent, acute urination with blood in the urine)<\/li><\/ul>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong>&nbsp;<\/p>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any&nbsp;side effects&nbsp;not mentioned in this information.&nbsp;You can also report&nbsp;side effects&nbsp;directly (see details below).&nbsp;By reporting&nbsp;side effects, you can help increase the safety of medicines.<\/p>\n\n\n\n<p>L\u00e4kemedelsverket<br>Box 26<br>751 03<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Gefitinib Avansor 250 mg film-coated tablets<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is gefitinib.&nbsp;Each tablet contains 250 mg of gefitinib.<\/li><li>The other ingredients (excipients) are sodium lauryl&nbsp;sulphate&nbsp;,&nbsp;lactose monohydrate&nbsp;, microcrystalline cellulose, povidone, croscarmellose sodium, magnesium stearate, polyvinyl alcohol, macrogol, talc, red iron oxide (E172), yellow iron oxide (E172) and black iron oxide.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Gefitinib Avansor brown, round, biconvex&nbsp;coated&nbsp;tablets (about 11 mm in diameter) marked with G9FB 250 on one side.<\/p>\n\n\n\n<p>Gefitinib Avansor is supplied in blister packs of 30 tablets or 30 x 1 tablets.&nbsp;The blister foil may be perforated or unperforated.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorisation Holder<\/p>\n\n\n\n<p>Avansor Pharma Oy<\/p>\n\n\n\n<p>Technician 14<\/p>\n\n\n\n<p>02150 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>Manufacturer<\/p>\n\n\n\n<p>Synthon Hispania SL<\/p>\n\n\n\n<p>Castell\u00f3 1, Pol\u00edgono Las Salinas<\/p>\n\n\n\n<p>08830 Sant Boi de Llobregat<\/p>\n\n\n\n<p>Spain &nbsp;<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Synthon BV<\/p>\n\n\n\n<p>Microweg 22<\/p>\n\n\n\n<p>6545 CM<\/p>\n\n\n\n<p>Nijmegen<\/p>\n\n\n\n<p>Netherlands<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gefitinib Avansor contains the active substance gefitinib which blocks a protein called epidermal growth factor receptor (EGFR). This protein is involved in the growth and spread of cancer cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2207],"tags":[12366,14586,12361,14582,14587,14585,12365,12364,14584,12363,12362,14583],"class_list":["post-13365","post","type-post","status-publish","format-standard","hentry","category-medicines","category-g","tag-benefits-of-gefitinib","tag-benefits-of-gefitinib-avansor","tag-gefitinib","tag-gefitinib-avansor","tag-gefitinib-avansor-side-effects","tag-gefitinib-avansor-tablet","tag-gefitinib-side-effects","tag-gefitinib-tablet","tag-what-gefitinib-avansor-is-used-for","tag-what-gefitinib-is-used-for","tag-what-is-gefitinib","tag-what-is-gefitinib-avansor"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13365","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13365"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13365\/revisions"}],"predecessor-version":[{"id":15584,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13365\/revisions\/15584"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13365"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13365"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}