{"id":13347,"date":"2021-09-06T07:12:58","date_gmt":"2021-09-06T07:12:58","guid":{"rendered":"https:\/\/zeepedia.com\/?p=13347"},"modified":"2021-11-09T10:59:25","modified_gmt":"2021-11-09T10:59:25","slug":"gastrographine","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/gastrographine\/","title":{"rendered":"Gastrographine &#8211; Sodium amidotrizoate \/ Meglumine amidotrizoate uses, dose and side effects"},"content":{"rendered":"\n<p>370 mg \/ l \/ ml&nbsp;oral \/ rectal solution<br>sodium amidotrizoate \/ meglumine amidotrizoate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Gastrography is and what it is used for<\/h2>\n\n\n\n<p>This medicine is for diagnostic purposes only.&nbsp;It is given either as a solution taken by mouth or as an&nbsp;enema&nbsp;(rectal solution).<\/p>\n\n\n\n<p>Gastrography is an&nbsp;X-ray contrast&nbsp;agent&nbsp;used in X-ray examinations, including&nbsp;computed tomography, of the gastrointestinal tract.&nbsp;It is used to depict constrictions, cavities, enlargements, foreign bodies,&nbsp;tumors, etc.<\/p>\n\n\n\n<p>The active, contrast-enhancing substance in Gastrography contains iodine.&nbsp;Iodine absorbs X-rays and thus creates a stronger contrast between the fluid and the surrounding&nbsp;tissue&nbsp;than what happens in the absence of contrast agents.&nbsp;This gives the doctor a better picture of the intestine and gives him a greater opportunity to make a correct diagnosis.<\/p>\n\n\n\n<p>Gastrography can sometimes be used to treat meconium ileus, a special form of intestinal obstruction.<\/p>\n\n\n\n<p>Sodium amidotrizoate and meglumine amidotrizoate contained in Gastrografin may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you receive Gastrography<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Gastrography<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to sodium amidotrizoate and meglumine amidotrizoate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>Gastrography should not be given undiluted:<ul><li>to children and dehydrated patients.<\/li><li>if you have a tendency to put food \/ drink in your esophagus (aspiration) or if your doctor suspects that you have an increased risk of aspiration.<\/li><li>if you have an abnormal connection (&nbsp;fistula&nbsp;) between the trachea and esophagus.<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before receiving Gastrography.<\/p>\n\n\n\n<p>Take special care with Gastrography<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (eg have hay fever or hives) or have&nbsp;bronchial asthma<\/li><li>if you are hypersensitive to or have previously reacted to iodinated contrast media<\/li><li>if you have suspected or known overactive&nbsp;thyroid gland&nbsp;or&nbsp;goiter&nbsp;(enlarged&nbsp;thyroid gland&nbsp;)<\/li><li>if you have a cardiovascular disease<\/li><li>if you have a very bad general condition<\/li><\/ul>\n\n\n\n<p>Hydrogenation<\/p>\n\n\n\n<p>It is important that you get enough fluids before and after the examination, as Gastrography can cause dehydration and&nbsp;electrolyte imbalance.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Before receiving Gastrography, tell your doctor if any of the above apply to you.&nbsp;The doctor will assess whether you can undergo the planned examination or not.<\/li><\/ul>\n\n\n\n<p><strong>Children<\/strong><\/p>\n\n\n\n<p>The doctor will check the thyroid function in newborns who have received Gastrografin, or if the mother has received Gastrografin during pregnancy.&nbsp;Gastrography can cause an underactive&nbsp;thyroid gland&nbsp;that may need treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Gastrography<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>This is especially true for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>beta-blockers&nbsp;(medicines for high&nbsp;blood pressure&nbsp;or irregular heartbeat)&nbsp;Hypersensitivity reactions&nbsp;may be exacerbated in patients treated with&nbsp;beta-blockers&nbsp;, especially in people with&nbsp;bronchial asthma&nbsp;.<\/li><li>Interleukin&nbsp;-2 (used in eg cancer and transplants)<\/li><\/ul>\n\n\n\n<p>Your doctor will advise you on what to do if any of the above apply to you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Gastrography with food, drink and alcohol<\/h2>\n\n\n\n<p>The bowel should be emptied before examination with Gastrography.&nbsp;Your doctor will advise you on this.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor if you are pregnant or planning to have a baby as Gastrografin should be used with caution during pregnancy.<\/li><li>If you are breast-feeding, talk to your doctor.&nbsp;Children who are breastfed are unlikely to be affected.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No known effect on the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Gastrography contains sodium<\/h2>\n\n\n\n<p>This medicine contains 374 mg of&nbsp;sodium&nbsp;(the main ingredient in table salt\/table salt) per 100 ml of solution.&nbsp;This corresponds to 18.7% of the maximum recommended daily&nbsp;sodium&nbsp;intake&nbsp;for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Gastrography<\/h2>\n\n\n\n<p>This medicine is always given by hospital staff.<\/p>\n\n\n\n<p>Gastrography will be given either as a solution taken orally or as an&nbsp;enema&nbsp;(rectal solution).&nbsp;Your doctor will calculate the&nbsp;dose&nbsp;of Gastrography that is right for you.&nbsp;Dose&nbsp;one depends on your age and the type of X-ray examination to be performed.&nbsp;Gastrography is sometimes given in combination with another contrast agent (barium sulfate).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have received too much Gastrography<\/h2>\n\n\n\n<p>Overdose is unlikely.&nbsp;If it should happen, after all, the doctor will treat the symptoms that appear.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.&nbsp;The side effects&nbsp;are usually mild to moderate and transient.&nbsp;However, serious and life-threatening reactions, as well as fatal reactions, have been reported.<\/p>\n\n\n\n<p><strong>Talk to your doctor or radiologist immediately if you experience any of the following rare reactions:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>As with other contrast agents,&nbsp;<strong>allergic-like reactions<\/strong>&nbsp;may occur, including severe reactions (&nbsp;shock&nbsp;) that require immediate medical attention.&nbsp;Slight swelling of the face, lips, tongue or throat, cough,&nbsp;itching&nbsp;, runny nose, sneezing and&nbsp;hives&nbsp;may be the first signs that a serious reaction is developing.<\/li><li><strong>Delayed allergy-like reactions<\/strong>&nbsp;, which occur hours or days after receiving Gastrography have been observed in rare cases.<\/li><li><strong>Severe skin reaction,<\/strong>&nbsp;with intense&nbsp;redness&nbsp;, skin detachment and large blisters (&nbsp;<em>toxic epidermal necrolysis<\/em>&nbsp;).<\/li><\/ul>\n\n\n\n<p>Other possible&nbsp;side effects&nbsp;are listed below,&nbsp;depending on how common they are:<\/p>\n\n\n\n<p><strong>Common&nbsp;adverse&nbsp;s<\/strong>&nbsp;(occurring in more than 1 in 100): nausea, vomiting, diarrhea<\/p>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;are<\/strong>&nbsp;(by less than 1 in 1000):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cardiac arrest, rapid&nbsp;pulse&nbsp;(&nbsp;<em>tachycardia<\/em>&nbsp;)<\/li><li>Shock&nbsp;, low&nbsp;blood pressure<\/li><li>Breathing difficulties (&nbsp;<em>dyspnoea&nbsp;,&nbsp;bronchospasm<\/em>&nbsp;), inhalation of contrast medium (&nbsp;<em>aspiration<\/em>&nbsp;), fluid in the lungs (&nbsp;<em>pulmonary&nbsp;edema&nbsp;after aspiration<\/em>&nbsp;),&nbsp;pneumonia&nbsp;(&nbsp;<em>aspiration pneumonia<\/em>&nbsp;)<\/li><li>Hole in the intestine (&nbsp;<em>intestinal&nbsp;perforation<\/em>&nbsp;), abdominal pain, blisters in the mouth<\/li><li>Disorders of consciousness, headache, dizziness<\/li><li>Overactive&nbsp;thyroid gland&nbsp;(&nbsp;<em>hyperthyroidism<\/em>&nbsp;)<\/li><li>Disturbed fluid \/ electrolyte balance<\/li><li>Hives&nbsp;(&nbsp;urticaria&nbsp;), rash, severe&nbsp;itching&nbsp;(&nbsp;<em>pruritus<\/em>&nbsp;), redness of the skin, swelling of the face (&nbsp;<em>edema<\/em>&nbsp;)<\/li><li>Fever, sweating.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users)&nbsp;<strong>:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Underactive&nbsp;thyroid gland&nbsp;(&nbsp;<em>hypothyroidism<\/em>&nbsp;)<\/li><\/ul>\n\n\n\n<p><strong>Gastrointestinal tract:<\/strong><\/p>\n\n\n\n<p>Gastrography can cause diarrhea, but it stops as soon as the bowel is emptied.&nbsp;Ongoing&nbsp;inflammation&nbsp;in the intestine may be temporarily exacerbated.&nbsp;If there is a blockage in the intestine, it may prevent gastrography from passing and tissue damage may occur.<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any side effects not mentioned in this information.&nbsp;You can also report side effects directly to the Medical Products Agency.&nbsp;By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to Store Gastrography<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>Store in the outer carton in order to protect from light.&nbsp;Store under X-ray protection.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bottle after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are sodium amidotrizoate and meglumine amidotrizoate.1 ml contains 0.1 g sodium amidotrizoate and 0.66 g meglumine amidotrizoate (370 mg I \/ ml)<\/li><li>Other excipients are disodium edetate, saccharin sodium, polysorbate 80, star anise oil, purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Gastrography is a clear, colorless to slightly yellow solution.<\/p>\n\n\n\n<p>Package contents: 10 bottles with 100 ml solution.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Bayer AB<\/p>\n\n\n\n<p>Box 606<\/p>\n\n\n\n<p>SE-169 26 Solna<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>BerliMed SA<\/p>\n\n\n\n<p>28806 Alcala de Henares, Madrid<\/p>\n\n\n\n<p>Spain<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This medicine is for diagnostic purposes only. It is given either as a solution taken by mouth or as an enema (rectal solution).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2207],"tags":[14636,14626,14631,14632,14622,14635,14625,14627,14630,14634,14633,14623,14624,14629],"class_list":["post-13347","post","type-post","status-publish","format-standard","hentry","category-medicines","category-g","tag-benefits-of-gastrographine","tag-benefits-of-meglumine-amidotrizoate","tag-benefits-of-sodium-amidotrizoate","tag-gastrographine","tag-meglumine-amidotrizoate","tag-side-effects-of-gastrographine","tag-side-effects-of-meglumine-amidotrizoate","tag-sodium-amidotrizoate","tag-sodium-amidotrizoate-side-effects","tag-what-gastrographine-is-used-for","tag-what-is-gastrographine","tag-what-is-meglumine-amidotrizoate","tag-what-meglumine-amidotrizoate-is-used-for","tag-what-sodium-amidotrizoate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=13347"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13347\/revisions"}],"predecessor-version":[{"id":15590,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/13347\/revisions\/15590"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=13347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=13347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=13347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}